KEGG   ENZYME: 2.3.1.291
Entry
EC 2.3.1.291                Enzyme                                 
Name
sphingoid base N-palmitoyltransferase;
mammalian ceramide synthase 5;
CERS5 (gene name);
LASS5 (gene name)
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
Sysname
palmitoyl-CoA:sphingoid base N-palmitoyltransferase
Reaction(IUBMB)
palmitoyl-CoA + a sphingoid base = an N-(palmitoyl)-sphingoid base + CoA
Reaction(KEGG)
(other) R01496 R06517
Substrate
palmitoyl-CoA [CPD:C00154];
sphingoid base
Product
N-(palmitoyl)-sphingoid base;
CoA [CPD:C00010]
Comment
Mammals have six ceramide synthases that exhibit relatively strict specificity regarding the chain-length of their acyl-CoA substrates. Ceramide synthase 5 (CERS5) is specific for palmitoyl-CoA as the acyl donor. It can use multiple sphingoid bases including sphinganine, sphingosine, and phytosphingosine.
History
EC 2.3.1.291 created 2019, modified 2019
Pathway
ec00600  Sphingolipid metabolism
ec01100  Metabolic pathways
Orthology
K23727  sphingoid base N-palmitoyltransferase
K28195  ceramide synthase
Genes
HSA253782(CERS6) 91012(CERS5)
PTR451891(CERS5) 741293(CERS6)
PPS100980816(CERS5) 100985038(CERS6)
GGO101126713(CERS6) 101131185(CERS5)
PON100452162(CERS6) 100454836(CERS5)
PPYG129010916(CERS5) 129031281(CERS6)
NLE100580966(CERS5) 100606355(CERS6)
HMH116461859(CERS5) 116810705(CERS6)
SSYN129489392(CERS6) 129491091(CERS5)
MCC704953(CERS6) 713449(CERS5)
MCF101926756(CERS6) 102116993(CERS5)
MTHB126931016 126932012
MNI105483289(CERS6) 105492850(CERS5)
CSAB103217252(CERS6) 103238299(CERS5)
CATY105576085 105580163(CERS6) 105580356(CERS5)
PANU101007470(CERS5) 101010164(CERS6)
TGE112635263(CERS5) 112635963(CERS6)
MLEU105528019(CERS5) 105545301(CERS6)
RRO104655030(CERS6) 104679692(CERS5)
RBB108520506(CERS6) 108543894(CERS5)
TFN117090138(CERS5) 117094902(CERS6)
PTEH111523514(CERS6) 111542010(CERS5)
CANG105507604(CERS5) 105525059(CERS6)
CJC100400191(CERS5) 100406593(CERS6)
SBQ101031310(CERS5) 101042109(CERS6)
CIMI108297035 108316081(CERS5)
ANAN105708871(CERS6) 105709374(CERS5)
CSYR103259017 103264586(CERS5) 103275446(CERS6)
MMUR105869901(CERS5) 105880675(CERS6)
LCAT123640385(CERS5) 123643926(CERS6)
PCOQ105815535(CERS6) 105818316(CERS5)
OGA100944197(CERS5) 100965109(CERS6)
MMU241447(Cers6) 71949(Cers5)
MCAL110285303(Cers6) 110310406(Cers5)
MPAH110318337(Cers6) 110334738(Cers5)
RNO366065(Cers6) 366984(Cers5)
MCOC116079726(Cers5) 116090263(Cers6)
ANU117703402(Cers6) 117718956(Cers5)
ASYL127667240(Cers5) 127685423(Cers6)
MUN110547416(Cers5) 110547789(Cers6)
CGE100761613(Cers6) 100774213(Cers5)
MAUA101835560(Cers5) 101842471(Cers6)
PROB127222453(Cers6) 127226073(Cers5)
PLEU114696680(Cers5) 114701812(Cers6)
MORG121433167(Cers6) 121441512(Cers5)
MFOT126488792 126489294
AAMP119819939(Cers6) 119823323(Cers5)
NGI103737993(Cers6) 103746545(Cers5)
HGL101701089(Cers5) 101713278(Cers6)
CPOC100713053(Cers6) 100713687(Cers5)
CCAN109689224(Cers6) 109695422(Cers5)
DORD105987427(Cers5) 105994475(Cers6)
DSP122106337(Cers5) 122120081(Cers6)
DMER138826407(Cers6) 138840560(Cers5)
PLOP125350590(Cers6) 125364921(Cers5)
NCAR124980060 124983009
MMMA107136644(Cers6) 107148621(Cers5)
ITI101956450(Cers5) 101967695(Cers6)
OCU100339974 100344726
OPI101516066(CERS6) 101531778(CERS5) 105942315
TUP102474397(CERS5) 102484493(CERS6)
GVR103599008(CERS5) 103604689(CERS6)
CFA477611(CERS5) 488387(CERS6)
CLUD112668042(CERS6) 112678319(CERS5)
VVP112916440(CERS6) 112921132(CERS5)
VLG121471816(CERS6) 121480093(CERS5)
NPO129498640(CERS6) 129517275(CERS5)
AML100473865(CERS6) 100474398(CERS5)
UMR103659527(CERS6) 103675475(CERS5)
UAH113250813(CERS6) 113257628(CERS5)
UAR123781107(CERS6) 123794754(CERS5)
ELK111145572 111157957
LLV125095680 125106796
MPUF101679078(CERS5) 101689555(CERS6)
MNP132013807(CERS6) 132019669(CERS5)
MLK131827132(CERS6) 131838780(CERS5)
NVS122891487(CERS5) 122902562(CERS6)
ORO101373517(CERS6) 101384709(CERS5)
EJU114223534(CERS6) 114225788(CERS5)
ZCA113919738(CERS6) 113922517(CERS5)
MLX118008859(CERS5) 118012363(CERS6)
NSU110591834(CERS6) 110593522(CERS5)
LWW102725602(CERS6) 102729437(CERS5)
FCA101084386(CERS6) 101087243(CERS5)
PYU121030655(CERS6) 121038586(CERS5)
PCOO112867277(CERS5) 112871758(CERS6)
PBG122473381(CERS5) 122481418(CERS6)
PVIV125170491(CERS5) 125171961(CERS6)
LRUF124501461 124515850
LGF123590761(CERS5) 123599026(CERS6)
AJU106969231 106970310
PTG102948771(CERS6) 102961799(CERS5)
PPAD109249101(CERS5) 109272468(CERS6)
PUC125911857 125920235
PLEZ122224539(CERS5) 122226200(CERS6)
HHV120237896(CERS5) 120242834(CERS6)
BTA530776(CERS5) 616901(CERS6)
BOM102271413(CERS5) 102282095(CERS6)
BIU109559116(CERS5) 109575183(CERS6) 109575194
BBUB102394124(CERS5) 102412267(CERS6)
BBIS105001498(CERS5) 105002359(CERS6)
CHX102170388 102170747(CERS5) 102176466(CERS6)
OAS101117661(CERS5) 101122252(CERS6)
BTAX128043173(CERS6) 128047483(CERS5)
CSUM138075877(CERS6) 138078161(CERS5)
ODA120854885(CERS6) 120858190(CERS5)
CCAD122427691(CERS5) 122453803(CERS6)
MREE136165357(CERS6) 136167142(CERS5)
OVR110146995(CERS5) 110150398(CERS6)
MBEZ129537121(CERS5) 129538651(CERS6)
SSC100126279(CERS6) 110260661(CERS5)
CFR102507747(CERS5) 102509169(CERS6)
CBAI105076226(CERS5) 105081974(CERS6)
CDK105091057(CERS6) 105097208(CERS5)
VPC102527280(CERS6) 102542785(CERS5)
BACU103007274(CERS5) 103008265(CERS6)
BMUS118898187(CERS6) 118902562(CERS5)
LVE103076535(CERS6) 103088889(CERS5)
OOR101282056(CERS6) 101282990(CERS5)
LALB132522323(CERS6) 132529581(CERS5)
GMF115841326(CERS5) 115850985(CERS6)
DDP132428585(CERS6) 132434528(CERS5)
DLE111172828(CERS6) 111174012(CERS5)
PCAD102983287(CERS6) 112064695(CERS5)
PSIU116756288(CERS6) 116760255(CERS5)
PPHC136125665(CERS6) 136130758(CERS5)
NASI112393999(CERS5) 112407376(CERS6)
ECB100052305(CERS6) 100059999(CERS5)
EPZ103546204(CERS5) 103567735(CERS6)
EAI106843426(CERS6) 106845048(CERS5)
MYB102246479(CERS6) 102262839(CERS5)
MYD102760303(CERS5) 102772688(CERS6)
MMYO118650380(CERS5) 118661337(CERS6)
MLF102436571(CERS5) 102440851(CERS6)
MDT132227603(CERS5) 132238571(CERS6)
MYUM139007144(CERS5) 139015260(CERS6)
PKL118709783(CERS6) 118729927(CERS5)
EFUS103283349(CERS6) 103285289(CERS5)
MNA107527415(CERS6) 107528263(CERS5)
DRO112318384(CERS5) 112322198(CERS6)
SHON118976441(CERS5) 118985744(CERS6)
AJM119042790(CERS5) 119045847(CERS6)
PDIC114494743(CERS6) 114512942(CERS5)
PHAS123813037(CERS5) 123823852(CERS6)
MMF118624460(CERS5) 118625117(CERS6)
PPAM129061757(CERS6) 129084856(CERS5)
HAI109390309(CERS6) 109393272(CERS5)
RFQ117026070(CERS6) 117029327(CERS5)
PALE102880099(CERS5) 102896376(CERS6)
PGIG120597041(CERS6) 120618175(CERS5)
PVP105290776(CERS6) 105297590(CERS5)
RAY107514286(CERS5) 107521030(CERS6)
MJV108385188(CERS6) 108406540(CERS5)
TOD119247907(CERS5) 119255898(CERS6)
SARA101551440(CERS6) 101558293(CERS5)
SFUM130019671(CERS6) 130029171(CERS5)
SETR126001797 126009167(CERS6) 126022550(CERS5)
LAV100660076(CERS6) 100674871(CERS5)
TMU101353143 101360537
ETF101644034(CERS6) 101646397(CERS5)
DNM101413515(CERS5) 101434663(CERS6)
MDO100024030(CERS6)
GAS123242227(CERS6) 123249238(CERS5)
SHR100924117(CERS6) 100929507(CERS5)
AFZ127539064 127554582
PCW110193982(CERS5) 110211536(CERS6)
TVP118838894(CERS6) 118851728(CERS5)
PBRV138154820(CERS6) 138164645(CERS5)
MLAO141507794(CERS6) 141514830(CERS5)
OAA100083235(CERS6) 114814501(CERS5)
TACU119932292(CERS6) 119933063(CERS5)
GGA426879(CERS5) 771503(CERS6)
PCOC116232888(CERS6) 116239661(CERS5)
MGP100544401(CERS6) 104913603(CERS5)
CJO107316742(CERS6) 107325704(CERS5)
TPAI128076801(CERS6) 128091855(CERS5)
LMUT125685531(CERS5) 125696558(CERS6)
NMEL110389242(CERS5) 110400020(CERS6)
APLA101789541(CERS5) 101804816(CERS6)
ACYG106029829(CERS6) 106047737(CERS5)
CATA118260209(CERS5) 118261711(CERS6)
AFUL116490567(CERS6) 116499847(CERS5)
TGU100225623(CERS6) 100231332(CERS5)
LSR110472763(CERS6) 110478539(CERS5)
SCAN103814409(CERS6) 103823883(CERS5)
PMOA120498351(CERS6) 120500684(CERS5)
OTC121333717(CERS5) 121335462(CERS6)
PRUF121353965(CERS5) 121356581(CERS6)
ATRC139585881(CERS5) 139593716(CERS6)
GFR102038365(CERS5) 102041033(CERS6)
FAB101816156(CERS5) 101818852(CERS6)
OMA130255514(CERS6) 130265926(CERS5)
PHI102105774(CERS5) 102111990(CERS6)
PMAJ107207352(CERS6) 107215686(CERS5)
CCAE111932124(CERS6) 111940481(CERS5)
CCW104694173(CERS6)
CBRC103613219(CERS5) 103616649(CERS6)
ACOE138099914(CERS5) 138113005(CERS6)
ETL114069957(CERS5) 114073750(CERS6)
ZAB102062883(CERS6) 102070566(CERS5)
ZLE135450161(CERS6) 135459221(CERS5)
ACHL103797040(CERS5) 103810631(CERS6)
SVG106862102(CERS6) 106863124(CERS5)
MMEA130576804(CERS6) 130584935(CERS5)
HRT120755375(CERS6) 120764411(CERS5)
SATI136363536(CERS6) 136372839(CERS5)
CCIC134047128(CERS6) 134054980(CERS5)
FPG101913508(CERS5) 101920423(CERS6)
FCH102052030(CERS5) 102052115(CERS6)
CCRI104161428 104162691(CERS5)
NNT104401556(CERS5) 104409598(CERS6)
SHAB115608675(CERS6) 115618785(CERS5)
ACUN113482330(CERS6) 113491052(CERS5)
TALA104360950(CERS5) 104365809(CERS6)
ACHC115343159(CERS6) 115350995(CERS5)
HALD104311178(CERS5) 104322568(CERS6)
HLE104831136(CERS5) 104831596(CERS6)
AGEN126043408 126046295
HHAR128144372(CERS6) 128151964(CERS5)
GCL127018542 127028395
CSTI104561729(CERS5)
LDI104340808(CERS5) 104351137(CERS6)
MNB103778648(CERS5)
DPUB104304738(CERS6) 104304827(CERS5)
PPUS135174275(CERS5) 135186145(CERS6)
AVIT104268928(CERS5) 104278558(CERS6)
BRHI104489274(CERS6) 104492605(CERS5)
EGZ104127999(CERS6) 104132784(CERS5)
NNI104010021(CERS6) 104011985(CERS5)
PCRI104032713(CERS5) 104035165(CERS6)
PCAO104050742(CERS5)
PADL103914717(CERS5) 103918187(CERS6)
AFOR103894934(CERS5) 103895414(CERS6)
FGA104076342(CERS5)
GSTE104252040(CERS5)
CBOY140644525(CERS5) 140657551(CERS6)
CLV102089975(CERS6) 102090443(CERS5)
CNIC135990422(CERS6) 136000598(CERS5)
MUI104538151 104548789(CERS5)
PGUU104458884(CERS5) 104461600(CERS6)
PLET104619430(CERS6) 104626983(CERS5)
EHS104511671(CERS5) 104513181
CMAC104487460(CERS5)
CUCA104054617(CERS6) 104055135(CERS5)
TEO104382953(CERS5)
BREG104632558(CERS5) 104642774
OHA104326608(CERS5) 104329048(CERS6)
ACAR104527401 104533047(CERS5)
CPEA104385608(CERS5) 104387526(CERS6)
CVF104284833(CERS5) 104294953(CERS6)
RTD128901229(CERS5) 128912925(CERS6)
CRID134518716(CERS6) 134526836(CERS5)
AAM106499105(CERS6) 106499436(CERS5)
AROW112974982(CERS6) 112975208(CERS5)
NPD112947661(CERS6) 112950288(CERS5)
TGT104573584(CERS6) 104575197(CERS5)
DNE112979643(CERS6) 112991671(CERS5)
SCAM104138588(CERS6) 104144041(CERS5)
ASN102380256(CERS6) 102383725(CERS5)
AMJ102562554(CERS6) 102569929(CERS5)
CPOO109322838(CERS6) 109324422(CERS5)
GGN109293341(CERS5) 109301529(CERS6)
PSS102452005(CERS5) 102460649(CERS6)
CMY102935736(CERS6) 102939527(CERS5)
CCAY125627787(CERS5) 125644896(CERS6)
DCC119845951(CERS5) 119863763(CERS6)
CPIC101938783(CERS5) 101947382(CERS6)
TST117884876(CERS6) 117888487(CERS5)
CABI116819314(CERS6) 116825906(CERS5)
MRV120374746(CERS6) 120391341(CERS5)
ACS100552770(cers5) 100563712(cers6)
ASAO132768287(CERS5) 132776628(CERS6)
PVT110074286(CERS5) 110076893(CERS6)
SUND121919678(CERS6) 121922289(CERS5)
PBI103050325(CERS5) 103062842(CERS6)
PMUR107287846(CERS6) 107302713(CERS5)
CTIG120316541(CERS5) 120318131(CERS6)
TSR106545288(CERS5) 106546629(CERS6)
PGUT117662796(CERS5) 117671124(CERS6)
PCAE139312758(CERS5) 139327201(CERS6)
APRI131190826(CERS5) 131202319(CERS6)
PTEX113434098(CERS6) 113447298(CERS5)
NSS113420170(CERS5) 113423598(CERS6)
VKO123016992(CERS6) 123019263(CERS5)
PMUA114586906(CERS5) 114606000(CERS6)
PRAF128407110(CERS5) 128423559(CERS6)
ZVI118081592(CERS5) 118093633(CERS6)
HCG128331418(CERS6) 128344238(CERS5)
GJA107119688(CERS6) 107122515(CERS5)
STOW125426129(CERS6) 125429405(CERS5)
EMC129324390(CERS6) 129329432(CERS5)
XLA108701361 108702983 399185(cers5.L) 495501(cers5.S)
XTR100101657(cers5) 100489264(cers6)
NPR108789979(CERS5) 108796981(CERS6)
RTEM120929081(CERS5) 120944047(CERS6)
ACAT141127036(CERS5) 141147028(CERS6)
BBUF120996226(CERS5) 121008458(CERS6)
BGAR122932495(CERS5) 122944931(CERS6)
DTC141049380(CERS6) 141049562(CERS5)
PWL138285397(CERS6) 138292326(CERS5)
MUO115466758(CERS5) 115474134(CERS6)
GSH117357903(CERS5)
DRE323020(cers5) 564867(cers6)
SRX107707597 107708313 107712190 107718462
SANH107677898 107694004 107698577
SGH107564136 107566328 107566751 107590873
CCAR109054523(cers6) 109096437 109101475 109102223
CAUA113039395 113040386 113052943(cers6) 113080556 113100953 113108267
CGIB127942858 127965543 127988163 128020071
PTET122327386(cers5) 122352073(cers6)
LROH127153284(cers5) 127171107(cers6)
GRF141340665(cers6)
OMC131529797(cers5) 131547412(cers6)
PPRM120486726(cers5) 120487022(cers6)
RKG130073753(cers5) 130105447(cers6)
MAMB125263379(cers5) 125270740(cers6)
CIDE127518473 127519781
CERY137028006(cers5) 137035626(cers6)
MASI127438108 127439211 127447646 127448416
TROS130549153(cers5) 130555419(cers6)
TDW130427700(cers6) 130430064(cers5)
MANU129451740(cers6) 129453749(cers5)
PDAB135721242(cers5) 135733571(cers6)
IPU108255109 108266969
IFU128608927(cers6) 128624998(cers5)
PHYP113526149(cers6) 113537857(cers5)
SMEO124383158(cers6) 124402259(cers5)
TFD113639059(cers5) 113654356(cers6)
TVC132837867(cers5) 132850259(cers6)
CGAR128511711(cers5) 128524631(cers6)
NGRA132874437(cers5) 132891940(cers6)
TRN134302098(cers5) 134324422(cers6)
AMEX103028461(cers6) 103035123(cers5)
CMAO118799283(cers5) 118806149(cers6)
EEE113577516(cers6) 113580588(cers5)
CHAR105907936(cers6) 105911943 122129874(cers5)
SPIL134071651 134078222(cers6) 134092660(cers5)
TRU101069548(cers5) 101069883(cers6) 105416273
TFS130522729(cers6) 130524850(cers5) 130530054
TNGGSTEN00033223G001 GSTEN00033850G001 GSTEN00034621G001
LCO104924188(cers6) 104928376(cers5) 104935436
NCC104956311 104961144 104967145(cers5)
TBEN117479466 117485735(cers6) 117489750(cers5)
CGOB115008103(cers5) 115011230 115026753(cers6)
PGEO117447251(cers5) 117450133 117466239(cers6)
GACU117538359(cers6) 117539539(cers5) 117540761
EMAC134866804(cers6) 134879861 134882889(cers5)
ELY117251840(cers6) 117257181(cers5) 117258080
EFO125889337(cers5) 125891306 125899476(cers6)
PLEP121946445 121949499(cers6) 121959331(cers5)
SLUC116048950(cers6) 116051423(cers5) 116062012
ECRA117942945(cers5) 117947484 117952532(cers6)
ESP116688268(cers5) 116693172 116697638(cers6)
PFLV114553897(cers5) 114558757 114564086(cers6)
GAT120828931 120833686(cers6) 120835436(cers5)
PPUG119222399 119228533(cers6) 119229875(cers5)
AFB129099895 129104563(cers6) 129105541(cers5)
CLUM117731072(cers5) 117750098(cers6)
PSWI130199218 130200145(cers6) 130209077(cers5)
CANA137783331(cers6) 137796209(cers5) 137800897
CVE137867568(cers6) 137873942(cers5) 137886927
MSAM119886324(cers5) 119904068(cers6) 119905629
SCHU122883333 122884933(cers5) 122885608(cers6)
CUD121505618(cers5) 121517503 121523085(cers6)
SPUL138589660 138592322(cers6) 138605879(cers5)
LMIX132978209(cers5) 132987369(cers6) 132989424
ALAT119021569(cers5) 119022413 119026496(cers6)
ASTR137595987(cers5) 137604791 137604850(cers6)
MZE101465150 101466824(cers6) 101466872(cers5)
ONL100693585 100695512(cers5) 100700285(cers6)
OAU116319368(cers5) 116323067(cers6) 116324792
OLA101156449(cers6) 101166550 101175231(cers5)
OML112144547(cers5) 112155476(cers6) 112159097
CSAI133446453(cers6) 133448365(cers5) 133457065
XMA102228308(cers5) 102231596 102234372(cers6)
XCO114135628(cers5) 114143560 114148177(cers6)
XHE116708203 116710701(cers5) 116722749(cers6)
PRET103461713(cers6) 103464664(cers5) 103467553
PFOR103134348(cers6) 103134554(cers5) 103145066
PLAI106939936 106948004 106959521(cers5)
PMEI106926443(cers6) 106928826 106929006(cers5)
GAF122828957 122834553(cers5) 122839969(cers6)
PPRL129361016(cers6) 129370228 129372647(cers5)
CVG107082007(cers6) 107097563 107101127(cers5)
CTUL119774092 119780272(cers6) 119788651(cers5)
GMU124856671(cers5) 124870794(cers6) 124874118
NFU107385395 107390055(cers6) 107391072
KMR108231679(cers5) 108232041 108240800(cers6)
ALIM106512928(cers6) 106517657 106523186 106536835(cers5)
NWH119411855(cers5) 119416757 119419127(cers6)
AOCE111572807(cers6) 111576050(cers5) 111588345
EJA138193309 138197311(cers5) 138200836(cers6)
BFRE138616637(cers5) 138623172(cers6) 138636353
MCEP125007024(cers5) 125017914 125018172(cers6)
CSEM103385495 103386746(cers5) 103392228(cers6)
POV109631475(cers6) 109635146 109635609(cers5)
SSEN122765528(cers6) 122768432(cers5) 122777674
SSOE131461394(cers5) 131468125 131475404(cers6)
HHIP117754754(cers6) 117761336(cers5) 117765323
HSP118103435(cers5) 118110575 118120188(cers6)
PPLT128442764 128456405(cers6) 128457911(cers5)
SMAU118282486(cers6) 118309462(cers5) 118316253
LCF108884121 108886075 108888662 108889493
SDU111217339 111218344(cers6) 111233599(cers5)
SLAL111648435(cers5) 111654505(cers6) 111667195
XGL120801585(cers6) 120803324 120807600(cers5)
HCQ109507970(cers5) 109526957(cers6) 109528680
SSCV125973569(cers6) 125977894(cers5) 125987712
SBIA133506924 133507660(cers5) 133512008(cers6)
PEE133403614 133408567(cers5) 133410528(cers6)
PTAO133480412 133483575(cers5) 133486455(cers6)
BPEC110155830(cers5) 110158056 110163953(cers6)
ENY140359406(cers6) 140363259 140365398(cers5)
MALB109957097(cers6) 109964292 109964621
BSPL114847408(cers6) 114855110(cers5) 114858540
SJO128355735(cers5) 128356863 128367910(cers6)
SSCO133977564(cers5) 133987630 133992933(cers6)
GMH115533462(cers6) 115552527 115557500(cers5)
SASA106566192 106566664 106581790(cers6) 106583695 106583702 106586203
STRU115150046(cers5) 115156050(cers6) 115160733 115168474 115207294
OTW112222046 112222283 112225207(cers6) 112236284 112246295(cers5)
OMY110492480 110494816 110501482(cers6) 110520083 110528577(cers5)
OGO124003996 124018470 124042801(cers6) 124043845 124045635
ONE115102035 115108751 115124173 115131870(cers5) 115145419(cers6)
OKI109866408 109869053 109871346(cers6) 109879088(cers5) 109899933
OKE118367098 118371421 118376336(cers5) 118381854 118386015(cers6)
OMM135519581 135527916 135540414 135541347(cers5) 135547194(cers6)
OCLA139368843 139371442 139380270 139406019 139413883
SALP111959739 111970771(cers5) 111974822 111976765 112071209
SNH120057836 120058239 120061373 120064402(cers6) 120065488
CCLU121536805 121538600 121545346 121552238(cers6) 121574729
ELS105016697(cers5) 105022463(cers6) 109614588
OEP134017864(cers6) 134018817 134027302(cers5)
SFM108920298 108931341(cers5)
PKI111835271(cers5) 111836391(cers6) 111852288
AANG118208513 118211526(cers5) 118223886(cers6)
AROT135235154 135238587(cers5) 135250783(cers6)
CCOG133110316(cers5) 133124746(cers6)
LOC102694432(cers6) 102696759(cers5)
PSPA121301802 121308831(cers5) 121321532 121323660
ARUT117401105 117404579 117426584 117433315 117966995
PSEX120526433 120531796(cers6)
LCM102345762(CERS5) 102354959(CERS6)
CMK103172411 103176381(cers6) 103190303
RTP109915855 109926281 109926491(cers6)
CPLA122539874 122543363 122551653(cers6)
HOC132805828(cers5) 132817431(cers6) 132830712
LERI129698587(cers6) 129710282 129714657
HAKA140728560 140741101(cers5) 140741376
PMRN116938597 116941053
LRJ133344763 133346045
BFO118424561
BBEL109478803
CIN778662 778663(lag1-like1)
SCLV120332580 120332645 120347204
SPU115926214 582683
AJJ139958883
APLC110973426
ARUN117300287
AAMU139949312
AFIL140162576
AJC117106772
SKO100373352
PFLL139141338
DMEDmel_CG3576(schlank)
DER6551335
DSE6612295
DSIDsimw501_GD28007(Dsim_GD28007)
DYADyak_GE16474
DAN26514187
DSR110181935
DPO4814776
DPE6603077
DMN108164752
DWI6648628
DGR6565933
DMODmoj_GI21529
DAZ108618444
DNV108655797
DHE111598102
DVI6634510(schlank)
CCAT101462193
BOD106623226
BDR105226359
RZE108359033
AOQ129237546
ALUD128858579
TDA119661815
MDE101890389
SCAC106081429
LCQ111685485
LSQ119600467
CVJ135957957(schlank)
GFS119637069
ECOE129945445
CLON129607822 129608129
HIS119656157
AGA1281413
ACOZ120953999
AARA120893705
AMER121591071
ASTE118504466
AMAP126558265
AFUN125764732
AMOU128297476
AMRS128719840
AALI118468545
ACOS131260550
AAG5571461
AALB109432412
ASUA134225234
CQUCpipJ_CPIJ012963
CPII120414849
CBRI134828219
CNS116349858
BCOO119084431
LLL129795625
PPAP129803627
AME727350
ACER107992919
ALAB122719222
ADR102677838
AFLR100863664
BIM100742830
BBIF117214553
BVK117242673
BVAN117156442
BHUN126866879
BTER100650450
BAFF126925542
BPYO122572179
BPAS132909006
FVI122536147
CCAL108621905 108623525
OBB114878598
OLG117602441
MGEN117229463
NMEA116432360
CGIG122400982
SOC105202455 105202760
MPHA105834422
AEC105147584
ACEP105623188
ACOC108691388
MZT108728601(schlank)
CCOA108778140
PBAR105429305
VEM105558072
COBS139105517(Schlank)
TLN139823848(Schlank)
HST105190345
DQU106748799
CFO105251260
FEX115242037
PMEC138944736(Schlank)
LHU105679186(schlank)
PGC109859190
OBO105276915
PCF106788439 106790267
PFUC122513576 122513581 122513582 122515260 122522526
VPS122634726
VCRB124429949
NVI100124217
CSOL105361245
TPRE106659191
LHT122510284
LBD127279274
MDL103573253
CGLO123267428
CTYP141528789(Schlank)
FAS105273287
DAM107046384
AGIF122856851
CINS118068585
VCAN122419541
CCIN107270358
DSM124409691
NPT124218027(schlank)
NFB124180347
NLO107224365
NVG124303919
AROA105685121
TCA103313757 103314249 656365 656449
TMOL138127623 138127624 138127626 138127678 138128210 138128211 138129019
DPA109544248
ESIM136412602(schlank)
EFOR136347533(schlank)
SOY115883107
AGRG126740209
ATD109604206
CSET123320817
HAXR123675900
AGB108906836
LDC111515909
DVV114331757 114332390 114334108
NVL108563163
APLN108745073
PPYR116161117 116162415 116168852 116169757 116177087
OTU111416207
BMOR101735559 101746948
MSEX115441317 115441318 115441319
DPLKGM_206860
BANY112045917 112053654
MJU123871131 123871132
NIQ126775451 126775453
VCD124532879 124533176
MCIX123663280 123663540
PMAC106712959 106712960 106712961
PPOT106107812 106107830
PXU106117619 106118032
BPHI137924145 137924241
PRAP110997056 110997057
PBX123713188 123713837
PNAP125056137 125060189
ZCE119833225 119833241
CCRC123700584 123700585
LSIN126974201 126974205
AAGE121727823 121727824
HAW110380732 110380734
HZE124639677 124639879
TNL113502767 113502772
SLIU111360032 111360375 111360450
OFU114358327 114361483 114361490 114363875
ONU135082122 135082388
ATRA106129893 106130029
GMW113514977 113515081
PXY105391568
PGW126376270 126376271
LGLY125233292 125236428 125236539 125240055
CSTB134749938 134749940
CFUM141430994 141430999 141431062
CFEL113377105
CCRN123302357
API100164476 100168238
DNX107162818
AGS114120474
RMD113551978
ACOO126842922
DVT126900888
BTAB109034368 109036148 109036156 109036161 109036176 109036278 109036335
CLEC106662291
HHAL106683384(schlank)
NLU111064616
HVI124362599
MQU128989643 128989688
PHUPhum_PHUM115780
FOC113202527
TPAL117640517
ZNE110827521
CSEC111864128
PAME138696907(schlank)
SGRE126298372
BROR134528312 134529724
IEL124157686
HAMR139686307(schlank)
FCD110845774 110848678 110855638
DPXDAPPUDRAFT_202055 DAPPUDRAFT_220106 DAPPUDRAFT_309267
DMK116919551 116922943 116922982
DPZ124325367 124328452 124343275
AFRA136029895 136029896
PVM113815251(schlank) 113819878 113819881 113819883 113819885 138859161
PJA122259873 122260028 122260091 122260102 122260122
PCHN125041733 125042092 125042093 125042094 125042183
PMOO119581958 119581959 119581961 119581962
HAME121877662 121877663 121880097 121880098 121880198
PCLA123757625 123757630 123757685 123760291 123760507
CQD128689240 128689469 128689471 128689480 138852889
PTRU123520078 123520079 123520080
ESN126981082 126981083
MNZ135213036 135213038 135213039 135213040 135213314
MRJ136835355 136835357 136835358 136835359 136835755(schlank)
PORN139748622
HAZT108664530 108664543 108672980 108679150 108680560 108680697 108680703 108680708 108680710
EAF111700142 111709730 111711161 111711434
LSM121116035(schlank)
TCF131880585 131882202 131886837 131892677
PPOI119096296
ISC8051766
DSV119442028
RSAN119387907
RMP119159735
VDE111252683
VJA111259237
GOE100907321
TUT107361924
DPTE113795595
DFR124496419
CSCU111642175
CVS136969149
PTEP107453820
ABRU129975042
UDV129227604
SDM118190732
LPOL106458468 106464745 106475190
PMEO129582967 129602802
CELCELE_C09G4.1(hyl-1) CELE_K02G10.6(hyl-2)
CBRCBG_14524(Cbr-hyl-2) CBG_15635(Cbr-hyl-1)
CRQGCK72_015265 GCK72_024303
NAINECAME_16352
BMYBM_BM4772(Bm4772)
LOALOAG_08632
TSPTsp_02045
HROHELRODRAFT_131704 HELRODRAFT_82517
LGILOTGIDRAFT_219624 LOTGIDRAFT_226091
PVUL126807700 126828723 126832542
PCAN112564114 112565008
LSAX138982388 138983245
BGT106074898 106079942
GAE121380469 121380788
HRF124121261 124121268 124123088
HRJ124273151 124276679 124276681
HASI137255251 137255622 137255624
HCRA139464964 139473369 139473403
CRG105332957 105335972
CANU128162543 128164270
CVN111111442 111114931
OED125665629 125667499
MYI110442549 110449442 110449450 110449461 110463359 110463365
PMAX117343242 117343783 117344169 117344187 117344188 117344192
AIRR138306994 138314338 138315078 138315079 138315081 138316415
MCAF127730687
MMER123531411 123532052 123532663
RPHI132732908 132740486 132749128 132751841 132752481
DPOL127840421 127842787 127855635
MAEA128225445 128232150 128239652
OBI106870521 106872705 106882761
OSN115219755 115225548 115230564
LJP135477555 135478118
LAK106153017 106153023
SMMSmp_042440
SHXMS3_00007422(CERS3_1)
OVIT265_11353
EGLEGR_07006
LLON135500250
NVE5511770 5515822
EPA110239328 110239732
ATEN116291181 116302865
ADF107356367
AMIL114965228
MCAZ138030137
MFOO137967603
PDAM113665414
SPIS111326256
DGT114517562 114522109
XEN124440805 124440809
HMG100197598 101237570
HSY130621496 130645108 130645110
RES135682261
ATHAT3G19260(LOH2)
ALY9321369
CRB17892809 17900891
CSAT104742498 104746311 104758311 104759882 104765789 104777883 109124739
EUSEUTSA_v10021239mg
BRP103837468 103859801 103869475
BNA106363310 106379803 106390312 106439526 106451897 111204768 125574803
BOE106296166 106323887 106336069
RSZ108806267 108859167 108862183 130503190 130512693 130512763
THJ104803454 104818546
CPAP110813806
CIT102616134
CICCICLE_v10028986mg
PVY116118499 116140883
MINC123215140
TCC18607938
GRA105762820 105782771
GHI107894263 107937954 107953398 121225645
GAB108464598 108478476
HSYR120120500 120120917 120122108 120149558 120186826 120187653 120204946 120211207
DZI111283138 111296248 111308039 111308933
EGR104418738 104453199 104453200
RARG115735998 115737200
GMX100803951 100804749
GSJ114388573 114419689
PVU137808742
VRA106767204
VAR108343571
VUN114176332
VUM124834377
CCAJ109801348
APRC113858556
MTR11444594
TPRA123924332
CAM101500130
PSAT127106692
VVO131602595
LJA130715131
ADU107469738
AIP107624103
AHF112715579 112784253
LANG109331407 109349439
PCIN129292152
QSAO6P43_031028
FVE101294739
AANS126783019
RCN112174438
PPER18768705
PMUM103335271 103335305
PAVI110771697
PDUL117637647
MDM103436493 114823140
MSYL126584690 126622136
PXB103941039 103942228
PCOX137725653
ZJU107427061
MNT21410145
CSAV115702927
CSV101205881
CMO103495235
BHJ120078363
MCHA111008054
CMAX111471005 111486095
CMOS111434695 111455365
CPEP111792771 111811319
RCU8275302
MEAN126662274
HBR110654605 110673298
MESC110619713 110624444
POP18097787 7457532
PEU105108030 105111629
PALZ118050807 118059220
PNZ133679385 133699909
JRE108982945 108988944
CILL122311158 122313806
CAVE132178542
AGLU133880896
QSU112025007
QLO115968467
TWL119990694 120001485 120005779
VVI104878786
VRI117911896
SLY101267275
SPEN107013278
SOT102597726
SSTN125850833
SDUL129885545
CANN107840291
LBB132599053
NTA107776446 107784206 107798179 107820623
NSY104247587 104249006
NTO104094407 104103202
NAU109206855 109223552
INI109161368 109161895
ITR116010721 116023335 116029241 116033004
SIND105169545 105172720
OEU111389098 111389117 111398669
EGT105952093 105953008 105957416
SSPL121742369 121745477
SMIL131000882
SHIS125216280
APAN127261099
PEBU140813246 140841878
HAN110877970
ECAD122600932
LSV111903161
CCAV112500607
DCR108200958
CSIN114264035
RVL131326775
AEW130754166 130774132 130779303 130781208
DLT127791002
BVG104903670
SOE110798070
CQI110699587 110738139
ATRI130806896
SLAF141599286
MOF131155794
NNU104601788 104606459
MING122063942 122085888
TSS122660475
PSOM113289506 113297751
OSA4332339(OJ1012B02.1)
DOSAOs03g0264000
OBR102702924
OGL127765041
BDI100822162
ATS109763657
TDC119285197 119290903
TAES123085368 123092671 123097976
TUA125552205
LPER127296125
LRD124708234 124708237
SBI8078808
ZMA100192594 100282886
MFLO136502070 136535955 136540207
SITA101782546
SVS117837587
PVIR120652923 120689859
PHAI112877993
PAUA133912115 133916467
TANG140765718
PDA103711170
EGU105034907 105046373
MUS103968954
ZOF122040269 122049658 122053922 122056680
DCT110108793 110114857
PEQ110018176 110031016
AOF109848904
MSIN131236391
ACAK137937835 137941852
NCOL116258655
ATR18428660
CJF131048311
SMOSELMODRAFT_170071
PPP112275510
CRECHLRE_17g726400v5
VCNVOLCADRAFT_55921
CSLCOCSUDRAFT_66904
APROF751_5640
ECUECU08_1350
EINEint_081340
EHEEHEL_081340
EROEROM_081360
NCENCER_100162
NGRNAEGRDRAFT_68950
 » show all
Reference
1  [PMID:16100120]
  Authors
Lahiri S, Futerman AH
  Title
LASS5 is a bona fide dihydroceramide synthase that selectively utilizes palmitoyl-CoA as acyl donor.
  Journal
J Biol Chem 280:33735-8 (2005)
DOI:10.1074/jbc.M506485200
  Sequence
[hsa:91012]
Reference
2  [PMID:15772421]
  Authors
Xu Z, Zhou J, McCoy DM, Mallampalli RK
  Title
LASS5 is the predominant ceramide synthase isoform involved in de novo sphingolipid synthesis in lung epithelia.
  Journal
J Lipid Res 46:1229-38 (2005)
DOI:10.1194/jlr.M500001-JLR200
  Sequence
[mmu:71949]
Reference
3  [PMID:15823095]
  Authors
Mizutani Y, Kihara A, Igarashi Y
  Title
Mammalian Lass6 and its related family members regulate synthesis of specific ceramides.
  Journal
Biochem J 390:263-71 (2005)
DOI:10.1042/BJ20050291
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.291
IUBMB Enzyme Nomenclature: 2.3.1.291
ExPASy - ENZYME nomenclature database: 2.3.1.291
BRENDA, the Enzyme Database: 2.3.1.291
LinkDB

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