| Entry |
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| Name |
benzoylsuccinyl-CoA thiolase;
bbsAB (gene names)
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| Class |
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
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| Sysname |
(S)-2-benzoylsuccinyl-CoA:CoA benzoyltransferase (benzoyl-CoA-forming)
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| Reaction(IUBMB) |
(S)-2-benzoylsuccinyl-CoA + CoA = benzoyl-CoA + succinyl-CoA [RN: R05587]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
The enzyme, characterized from the bacteria Thauera aromatica and Geobacter metallireducens, participates in an anaerobic toluene degradation pathway.
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| History |
EC 2.3.1.310 created 2022
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| Pathway |
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| Orthology |
| K07549 | benzoylsuccinyl-CoA thiolase BbsA subunit |
| K07550 | benzoylsuccinyl-CoA thiolase BbsB subunit |
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| Genes |
| EBA: | c2A315(bbsB) c2A316(bbsA) |
| APET: | ToN1_01600(bbsB) ToN1_01610(bbsA) |
| AZI: | AzCIB_4525 AzCIB_4526 |
| AZD: | CDA09_07420 CDA09_07425 CDA09_21990 CDA09_21995 |
| TAK: | Tharo_3089 Tharo_3090 |
| GME: | Gmet_1528(bbsA) Gmet_1529(bbsB) |
| GEO: | Geob_2427(bbsA) Geob_2428(bbsB) |
| DTO: | TOL2_C01480(bbsB) TOL2_C04900(bhsA) |
| DMM: | dnm_089750(bhsA) dnm_089760(bhsB) |
| DGI: | Desgi_0641 Desgi_0642 |
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| Reference |
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| Authors |
Leuthner B, Heider J |
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| Title |
Anaerobic toluene catabolism of Thauera aromatica: the bbs operon codes for enzymes of beta oxidation of the intermediate benzylsuccinate. |
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| Journal |
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| Sequence |
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| Reference |
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| Authors |
Weidenweber S, Schuhle K, Lippert ML, Mock J, Seubert A, Demmer U, Ermler U, Heider J. |
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| Title |
Finis tolueni: a new type of thiolase with an integrated Zn-finger subunit catalyzes the final step of anaerobic toluene metabolism. |
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| Journal |
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| Sequence |
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| Other DBs |
| ExPASy - ENZYME nomenclature database: | 2.3.1.310 |
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| LinkDB |
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