KEGG   ENZYME: 2.3.2.32
Entry
EC 2.3.2.32                 Enzyme                                 
Name
cullin-RING-type E3 NEDD8 transferase;
RBX1 (gene name)
Class
Transferases;
Acyltransferases;
Aminoacyltransferases
Sysname
[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine:[cullin] [NEDD8-protein] transferase (isopeptide bond-forming; RING-type)
Reaction(IUBMB)
[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine + [cullin]-L-lysine = [E2 NEDD8-conjugating enzyme]-L-cysteine + [cullin]-N6-[NEDD8-protein]-yl-L-lysine
Substrate
[E2 NEDD8-conjugating enzyme]-S-[NEDD8-protein]-yl-L-cysteine;
[cullin]-L-lysine
Product
[E2 NEDD8-conjugating enzyme]-L-cysteine;
[cullin]-N6-[NEDD8-protein]-yl-L-lysine
Comment
Some RING-type E3 ubiquitin transferase (EC 2.3.2.27) are not able to bind a substrate protein directly. Instead, they form a complex with a cullin scaffold protein and a substrate recognition module, which is named CRL for Cullin-RING-Ligase. The cullin protein needs to be activated by the ubiquitin-like protein NEDD8 in a process known as neddylation. The transfer of NEDD8 from a NEDD8-specific E2 enzyme onto the cullin protein is a secondary function of the RING-type E3 ubiquitin transferase in the CRL complex. The process requires auxiliary factors that belong to the DCN1 (defective in cullin neddylation 1) family.
History
EC 2.3.2.32 created 2017
Orthology
K03868  E3 ubiquitin-protein ligase RBX1
Genes
HSA9978(RBX1)
PTR458860(RBX1)
PPS100970959 100981636(RBX1)
GGO101151577(RBX1)
PON100441665(RBX1)
NLE100596079(RBX1)
MCC710252(RBX1)
MCF102132483(RBX1)
CSAB103223367(RBX1)
CATY105572541(RBX1)
PANU101025661(RBX1)
TGE112633503(RBX1)
RRO104673455(RBX1)
RBB108528465(RBX1)
TFN117096433(RBX1)
PTEH111532697 111548968(RBX1)
CJC100391523(RBX1)
SBQ101031903(RBX1)
CSYR103260489(RBX1)
MMUR105858549(RBX1)
LCAT123640318(RBX1)
OGA100963359(RBX1)
MMU56438(Rbx1)
MCAL110310464(Rbx1)
MPAH110334961(Rbx1)
RNO300084(Rbx1)
MCOC116076358(Rbx1)
MUN110550435(Rbx1)
CGE100762556(Rbx1)
MAUA101838028(Rbx1)
PLEU114694298(Rbx1) 114707186
MORG121444018 121461000(Rbx1)
AAMP119823435(Rbx1)
NGI103743488(Rbx1)
HGL101712475(Rbx1)
CPOC100714763(Rbx1)
CCAN109686914(Rbx1)
DORD105992090(Rbx1)
DSP122123619(Rbx1)
NCAR124983356
OCU103352470(RBX1)
OPI101519048(RBX1)
TUP102468598(RBX1)
CFA474494(RBX1)
VVP112934005(RBX1)
VLG121491679(RBX1)
UMR103674160(RBX1)
UAH113241739(RBX1)
UAR123780699(RBX1)
ELK111157501
LLV125106731
MPUF101687674(RBX1)
ORO101363104(RBX1)
EJU114218392(RBX1)
ZCA113911560 113921968(RBX1)
MLX117998640(RBX1)
FCA101087758(RBX1)
PYU121040293(RBX1)
PBG122472803(RBX1)
PTG102955881(RBX1)
PPAD109265611(RBX1)
AJU113602716(RBX1)
HHV120234320(RBX1) 120234672 120236827
BTA518880(RBX1) 780968
BOM102272719(RBX1)
BIU109559850(RBX1)
BBUB102414522(RBX1)
CHX102187112(RBX1) 102188771
OAS101109871(RBX1)
ODA120857602(RBX1)
CCAD122423474(RBX1) 122426581 122445122
SSC110260638(RBX1)
CFR102515877(RBX1)
CBAI105073197(RBX1)
CDK105091911(RBX1)
VPC102535913(RBX1)
BACU102998295(RBX1)
LVE103090829(RBX1)
OOR101287254(RBX1) 101289349
DLE111186303(RBX1)
PCAD102983946(RBX1)
PSIU116749210 116760644(RBX1)
ECB100055581(RBX1)
EPZ103556120(RBX1)
EAI106842455(RBX1)
MYB102243164 102243482 102254932 102260998(RBX1)
MYD102760790(RBX1)
MMYO118650853(RBX1) 118659026 118663966 118663967
MLF102431403(RBX1)
MNA107531277(RBX1)
PKL118730800(RBX1)
HAI109392275(RBX1)
DRO112321770(RBX1)
SHON119002280(RBX1)
AJM119060371(RBX1)
PDIC114513192(RBX1)
PHAS123816194(RBX1)
MMF118618357 118624414(RBX1)
RFQ117029081(RBX1)
PALE102893437(RBX1)
PGIG120602973(RBX1)
PVP105298053(RBX1)
RAY107519712(RBX1)
MJV108394317(RBX1)
TOD119247226(RBX1)
SARA101542238(RBX1) 101554111
LAV100657479(RBX1)
TMU101349359
DNM101444027(RBX1)
MDO100013521(RBX1)
GAS123250747(RBX1)
SHR100918404(RBX1)
PCW110205825(RBX1)
OAA100076928(RBX1)
GGA418001(RBX1)
PCOC116233383(RBX1)
MGP100543550(RBX1)
CJO107312930(RBX1)
NMEL110392307(RBX1)
APLA101796040(RBX1)
ACYG106035919(RBX1)
AFUL116501779(RBX1)
TGU100190092(RBX1)
LSR110483089(RBX1)
SCAN103813288(RBX1)
PMOA120510088(RBX1)
OTC121342452(RBX1)
PRUF121361199(RBX1)
GFR102037823(RBX1)
FAB101806409(RBX1)
PHI102102832(RBX1)
PMAJ107204430(RBX1)
CCAE111934630(RBX1)
CCW104696532(RBX1)
ETL114058064(RBX1)
ZAB102069638(RBX1)
FPG101916874(RBX1)
FCH102049129(RBX1)
CLV102095842(RBX1)
ACUN113488055(RBX1)
TALA104364386(RBX1)
PADL103915729(RBX1)
ACHC115352685(RBX1)
AAM106488968(RBX1)
AROW112965730(RBX1)
NPD112946469(RBX1)
DNE112984067(RBX1)
ASN102372162(RBX1)
AMJ102571619(RBX1)
CPOO109316717(RBX1)
GGN109295958(RBX1)
PSS102451113(RBX1)
CMY102943754(RBX1)
CPIC101936281(RBX1)
TST117880076(RBX1)
CABI116829058(RBX1)
MRV120381008 120384740
ACS100566553(rbx1)
PVT110076073(RBX1)
SUND121932202(RBX1)
PBI103065423(RBX1)
PMUR107285413(RBX1)
TSR106537822(RBX1) 106553210
PGUT117655425(RBX1)
VKO123036074(RBX1)
PMUA114605459(RBX1)
ZVI118091458(RBX1)
GJA107117140(RBX1)
STOW125435698(RBX1)
XLA108714482(rbx1.L) 108715730(rbx1.S)
XTR100379935(rbx1)
NPR108788200(RBX1)
RTEM120945492(RBX1)
BBUF120979112(RBX1)
BGAR122943674(RBX1)
DRE449846(rbx1)
SRX107723609 107748812
SANH107672143(rbx1) 107695112
SGH107580054 107602336(rbx1)
CCAR109076699(rbx1)
CAUA113046818 113047604
PPRM120462132(rbx1)
MAMB125273687(rbx1)
IPU100528272(rbx1) 108279000 108279790
PHYP113524074(rbx1)
SMEO124381909(rbx1)
TFD113640136(rbx1)
AMEX107197156(rbx1)
EEE113583718(rbx1)
TRU101079814 115248454 115249889 115249890
TNGGSTEN00008999G001
LCO104932083(rbx1)
NCC104945083(rbx1)
CGOB115012294(rbx1)
ELY117268068(rbx1)
PLEP121956973(rbx1) 121966503
SLUC116065292(rbx1)
ECRA117958649(rbx1)
PFLV114569772(rbx1)
GAT120827413(rbx1)
PPUG119220154(rbx1)
MSAM119884920(rbx1)
CUD121529177(rbx1)
ALAT119013730(rbx1)
MZE101480103(rbx1)
ONL100696705(rbx1)
OAU116327876(rbx1)
OLA101170590(rbx1)
OML112146889(rbx1)
XMA102233269(rbx1)
XCO114160562(rbx1)
XHE116736204(rbx1)
PRET103468459(rbx1)
PFOR103153424(rbx1)
PLAI106961597(rbx1)
PMEI106930562(rbx1)
GAF122822198(rbx1)
CVG107093096(rbx1)
CTUL119799435(rbx1)
GMU124863171 124864508
NFU107376330(rbx1)
KMR108236172(rbx1)
ALIM106520678(rbx1)
NWH119422119(rbx1)
AOCE111570331(rbx1)
CSEM103393328(rbx1)
POV109643626(rbx1)
SSEN122785647(rbx1)
HHIP117766292(rbx1)
HSP118122773(rbx1)
LCF108877581(rbx1)
SDU111230345(rbx1)
SLAL111645594 111647571(rbx1)
XGL120783375(rbx1)
HCQ109514860(rbx1)
BPEC110162377(rbx1)
MALB109952664(rbx1)
BSPL114860326 114860329(rbx1)
SASA100136424(rbx1) 106601243(rbx1)
OTW112226161 112247600 112258810
OMY100301858(rbx1) 110486413
OGO124000287 124015661
ONE115104268 115109887
SALP111965561 111981970 112072990
SNH120034372 120037660
ELS105025789(rbx1)
SFM108926071(rbx1) 108939936 108939944
PKI111845210(rbx1) 111853244
AANG118216689(rbx1) 118218515
PSPA121306188(rbx1)
LCM102352187(RBX1)
CMK103189242(rbx1)
RTP109921792(rbx1)
BFO118419573
BBEL109487751
CIN100182516
SCLV120342351
SPU115918507 591601
APLC110984414
DMEDmel_CG16982(Roc1a) Dmel_CG16988(Roc1b)
DER6545155 6555510
DSE6610179 6615886
DSIDsimw501_GD11014(Dsim_GD11014) Dsimw501_GD16520(Dsim_GD16520)
DYADyak_GE16630 Dyak_GE17622 Dyak_GE21084
DAN6496786 6500186 6504852
DSR110178156 110181408 110181527 110181780
DPODpse_GA14260 Dpse_GA22841 Dpse_GA23017 Dpse_GA24410
DPE6590337 6597670 6599516 6600097
DMN108151726 108157979 108158743 108164784
DWI6637565 6638168 6642959 6644881 6645940 6652807 6653602
DGR6558239 6559441 6562654 6569282
DMODmoj_GI14277 Dmoj_GI16422 Dmoj_GI16738 Dmoj_GI20142 Dmoj_GI25778
DAZ108609727 108613301 108618888 108620113
DNV108651181 108655043 108656193 115562720
DHE111601088 111603518 111604779 111605125
DVI6622041 6626811 6634529 6635721
CCAT101452937 101454374
BOD106621760 106627011 118679759 118681423
MDE101897666 101900642
SCAC106096045
LCQ111684342 111688763
LSQ119604129 119604908
HIS119656903
AGAAgaP_AGAP005202
ACOZ120947991
AARA120898375
ASTE118509359
AAG5565270
AALB109423057 109432379 115260693
CQUCpipJ_CPIJ012886
CPII120417029
CNS116347560
BCOO119080998
AME408691
ACER107996873
ALAB122718323
BIM100750218
BBIF117206781
BVK117236796
BVAN117155771
BTER100643234
BPYO122575860
CCAL108631453
OBB114871947
MGEN117217818
NMEA116430110
CGIG122398060
SOC105195164
MPHA105839647
AEC105148347
ACEP105626311
PBAR105432274
VEM105568857
HST105188519
DQU106740675
CFO105252239
FEX115233657
LHU105674184
PGC109852514
OBO105284276
PCF106787165
PFUC122515250
VPS122636059
NVI100115578
CSOL105361251
TPRE106652040
MDL103578781
CGLO123261074
FAS105267552
DAM107041044
AGIF122852012
CCIN107266769
TCA655935
DPA109536288
SOY115874647
ATD109603625 109606400
CSET123309188
AGB108917391
LDC111512846
NVL108557707
APLN108733335
PPYR116168719
OTU111417661
BMOR692971
BMAN114248509
MSEX115445862
DPLKGM_211860
BANY112053517
PMAC106708735
PPOT106100422
PXU106123473
PRAP110992851
ZCE119833226
HAW110372277
TNL113508302
SLIU111358319
OFU114365077
PXY105397966
API100162035 100162097
DNX107162314
AGS114120761 114122273 114123391
RMD113552893 113556289
BTAB109044484
DCI103511407 103524839 103524844
CLEC106666282
HHAL106682125
NLU111058671
PHUPhum_PHUM087130
FOC113211873
TPAL117639298
ZNE110832453
CSEC111870542
FCD110848901
DPXDAPPUDRAFT_40730 DAPPUDRAFT_60651 DAPPUDRAFT_65504 DAPPUDRAFT_65506 DAPPUDRAFT_65509
DMK116925355
PVM113818542
PJA122244209
PCHN125046917
HAME121862336
PCLA123756750
PTRU123509381
HAZT108678153
EAF111714026
LSM121123682
PPOI119099374 119099407 119105838 119105852
ISCIscW_ISCW018511
DSV119449384
RSAN119382413
RMP119178187
VDE111249014
VJA111266216
TUT107362230
DPTE113789362
DFR124497975
CSCU111619728 111633535 111638739 111640208
PTEP107454093
SDM118193171
CELCELE_ZK287.5(rbx-1)
CBRCBG_19342(Cbr-rbx-1)
BMYBM_BM14000(Bma-rbx-1)
LOALOAG_03239
NAINECAME_02269
HROHELRODRAFT_86393
LGILOTGIDRAFT_206883
PCAN112559116
GAE121375242
HRF124143675
HRJ124284529
CRG105317988
MYI110455961
PMAX117328726
MMER123557832
OBI106882699
OSN115218629
LAK106150763
OVIT265_11722
EGLEGR_00753 EGR_04378
NVE5509443
EPA110249442
ATEN116291507
ADF107349974
AMIL114969829
PDAM113677930
SPIS111341613
DGT114530307
XEN124445670
HMG100204043
TADTRIADDRAFT_50330
AQU100636037
ATHAT3G42830 AT5G20570(RBX1)
ALY9308017
CRB17881315 17886885
CSAT104706402 104710838 104736126 104770432 104780213 104790623
EUSEUTSA_v10015047mg
BRP103845664 103851357 103856451
BNA106371726 106385158 106408993 106425686 106434840 111213972
BOE106316076 106325067 106332287
RSZ108817515 108827876 108846167
THJ104808880 104811002 104815338 104826593
CPAP110817690
CIT102613162 102622192
CICCICLE_v10009952mg CICLE_v10026815mg
PVY116120238 116126404
MINC123193858 123200043
TCC18588272
GRA105767665 105792942 105795701
GHI107903283 107929974 107932188 107932799 107960807 121204775
GAB108468083 108469121 108488019
DZI111274703 111286458 111299190 111303054
EGR104436408 104437993 104438034 104439002
GMX100500045 100526919 100789570 100798515
GSJ114374500 114378027 114378451 114397039 114417297
PVUPHAVU_005G114500g PHAVU_011G105100g
VRA106754365 106761091 106761707
VAR108333295 108338955
VUN114168583 114183876
CCAJ109790424 109806089
APRC113855424 113858391
MTRMTR_2g088570 MTR_4g046877
CAM101496300 101503002
LJALj0g3v0042719.1(Lj0g3v0042719.1) Lj0g3v0262469.1(Lj0g3v0262469.1) Lj3g3v1339080.1(Lj3g3v1339080.1)
ADU107462077 107477744
AIP107613945 107624456 107629957
AHF112707013 112737543 112771395 112789617
LANG109325667 109352320 109353407
FVE101301042 101302106 101307444
RCN112174210 112179375 112196401 112199925
PPER18785603 18786902
PMUM103331948 103331952
PAVI110746319 110748081 110769275
PDUL117617435 117619981
MDM103405253 103439121 103450248
PXB103942118 103964642
ZJU107423885
MNT21410023
CSV101209538 101209687
CMO103492371 103498857
BHJ120071482 120079716
MCHA111016444 111021926
CMAX111465785 111467761 111485682
CMOS111440096 111444049 111461500
CPEP111779645 111793107 111798730
RCU8259356 8281168
JCU105631381 105637971
HBR110634308 110639647 110664598
MESC110612954 110626830
POP18094715 18100330 7471662
PEU105133432 105133967
PALZ118034841 118037983 118048083
JRE108981134 109009026
QSU111993014 112001342 112001674
QLO115969583 115988613
TWL119982225 119992954 120005634
VVI100246271 100259489
VRI117921577 117925760
SLY101249890 101259644
SPEN107005489 107021447
SOT102583049 102595356 107059797
CANN107840900 107861671 107876064
NTA107759896 107776199 107780326 107784644 107824015 107829306
NSY104214032 104219570 104236463
NTO104092250 104104527 104120680
NAU109217886 109221000 109225596 109239640
INI109147674 109158438 109186622
ITR115999746 116012189 116019189
SIND105161929 105173683
OEU111379972 111384856 111411455
EGT105968134 105970859
SSPL121746682 121750403 121783554 121786269 121793382 121801447
HAN110880261 110893699 110897767 110916508
ECAD122588767 122588803 122607398
LSV111882147 111892622 111902717
CCAV112509462 112511044 112516390
DCR108193846 108211059 108219676 108224330
CSIN114302496 114302498
BVG104883468 104899743
SOE110798000 110804025
CQI110682960 110684393 110688077 110733846
NNU104600540
MING122076653 122083431
TSS122640521 122641411 122648264 122653778 122658402 122663617 122667975
PSOM113293923 113326900 113327705 113339765
NCOL116259708 116262899
OSA4326152 4330476
DOSAOs01t0106800-01(Os01g0106800) Os02t0708300-01(Os02g0708300)
OBR102707436 102714616
BDI100826136 100841533
ATS109737146 109777151
TDC119266566 119274241 119317601 119323775
TAES123068146 123128144 123137940 123145238 123172046 123172497
TUA125514298 125542236
SBI8073850 8079092
ZMA100192928 103634739 103649912
SITA101761659 101778950
SVS117835140 117856011
PVIR120649760 120656974 120676393 120706260
PHAI112879972 112893014
PDA103701991 103711519 120113304
EGU105056281 105058733
MUS103968770 103977230 103981809 103987360
DCT110096489 110100420
PEQ110019661
AOF109828983 109844953
ATR105421056 18439492
SMOSELMODRAFT_269625 SELMODRAFT_269937
PPP112284365 112288983 112295784
CRECHLRE_12g543450v5
VCNVOLCADRAFT_75918
MNGMNEG_4176
CSLCOCSUDRAFT_21809
APROF751_6626
OLUOSTLU_119493(rbx1)
OTAOT_ostta02g00480
BPGBathy07g04140
MISMICPUN_113936(RBX1)
MPPMICPUCDRAFT_25062
CMECYME_CMQ353C
GSLGasu_48170
CCPCHC_T00009192001
SCEYOL133W(HRT1)
SEUBDI49_2274
SPAOSPAR_O00240
AGOAGOS_ADL181W
ERCEcym_2029
KLAKLLA0_E07151g
KMXKLMA_70161(HRT1)
LTHKLTH0F19228g
VPOKpol_1014p16
ZROZYRO0C03058g
CGRCAGL0E01567g
NCSNCAS_0C04480(NCAS0C04480)
NDINDAI_0G03860(NDAI0G03860)
TPFTPHA_0P01470(TPHA0P01470)
TBLTBLA_0B08710(TBLA0B08710)
TDLTDEL_0A00470(TDEL0A00470)
TGBHG536_0E02510
KAFKAFR_0C01780(KAFR0C01780)
KNGKNAG_0A01280(KNAG0A01280)
ZMKHG535_0F01980
PPAPAS_chr4_0436
DHADEHA2F17666g
PICPICST_37145(HRT1)
SPAASPAPADRAFT_61897
LELLELG_02061
CALCAALFM_C302450WA(HRT1)
CTPCTRG_02424
COTCORT_0B04130
CDUCD36_82410
CTENCANTEDRAFT_103250
YLIYALI0B17358g
CLUCLUG_04212
CLUSA9F13_04g03124
CAURCJI97_001914
PKZC5L36_0C07065
BNNFOA43_001196
BBRXBRETT_002341
OPAHPODL_05342
SLUDSCDLUD_005007
NTENEUTE1DRAFT116888(NEUTE1DRAFT_116888)
SMPSMAC_07095
PANPODANSg5275
MTMMYCTH_2304045
CTHRCTHT_0023610
MGRMGG_08844
PPEIPpBr36_00516
TMNUCRPA7_1639
SSCKSPSK_02774
FGRFGSG_02497
FPUFPSE_08616
FVRFVEG_09167
FOXFOXG_10518
NHENECHADRAFT_42915
TRETRIREDRAFT_121950
TRRM419DRAFT_104643
MAWMAC_01896
MAJMAA_00593
CMTCCM_05836
VALVDBG_08639
VDAVDAG_06301
CFJCFIO01_11879
CHIGCH63R_02620
SAPOSAPIO_CDS3010
ELAUCREL1_3121
PFYPFICI_12609
SSLSS1G_00027
BFUBCIN_03g07500(Bchrt1)
MBEMBM_08230
PSCOLY89DRAFT_688943
GLZGLAREA_01075
ANIAN8844.2
AFMAFUA_5G05790
ACTACLA_009060
NFINFIA_037330
AORAO090009000684
ANGANI_1_294154(An17g02100)
AFVAFLA_010686
ALUCAKAW2_70780S(RBX1)
ACHEACHE_11205A(RBX1)
APUUAPUU_70423A(RBX1)
PCSPc20g00850
PDPPDIP_22460
TMFPMAA_086620
TRGTRUGW13939_07977
CIMCIMG_06244
CPWCPC735_027760
UREUREG_04145
PBLPAAG_07371
PBNPADG_05868
ABEARB_07022
TVETRV_07648
AJEHCAG_03036
BGHBDBG_08548
PNOSNOG_09105
PTEPTT_16968
BZECOCCADRAFT_95811
BSCCOCSADRAFT_82242
BORCOCMIDRAFT_103083
AALTCC77DRAFT_1049904
ZTRMYCGRDRAFT_46230
PFJMYCFIDRAFT_88404
FFUCLAFUR5_07092
BCOMBAUCODRAFT_106019
NPAUCRNP2_3000
TMLGSTUM_00002417001
SPOSPAC23H4.18c(rbx1)
CNECNB03140
CNBCNBB2560
CNGCNAG_03823
CGICGB_A3220W
TMSTREMEDRAFT_30658
TVSTRAVEDRAFT_31548
DSQDICSQDRAFT_136248
PCOPHACADRAFT_253837
SHSSTEHIDRAFT_96405
HIRHETIRDRAFT_441743
PSQPUNSTDRAFT_80891
ADLAURDEDRAFT_83065
FMEFOMMEDRAFT_126450
GTRGLOTRDRAFT_101369
LBCLACBIDRAFT_317013
MRRMoror_7592
MOREE1B28_013366(RBX1)
CCICC1G_08674
SCMSCHCODRAFT_77263
ABPAGABI1DRAFT130185(AGABI1DRAFT_130185)
ABVAGABI2DRAFT139777(AGABI2DRAFT_139777)
PCUBJR316_0006035 JR316_0013262
CPUTCONPUDRAFT_106740
SLASERLADRAFT_385744
WSEWALSEDRAFT_27573
WICJ056_004250
UMAUMAG_10917
PFPPFL1_04680
MGLMGL_0788
MRTMRET_0028
PGRPGTG_10430 PGTG_18192
MLRMELLADRAFT_106109
ECUECU01_1095
EINEint_011010
EHEEHEL_010980
EROEROM_010900
NCENCER_101168
MBRMONBRDRAFT_18418
SREPTSG_04800
DDIDDB_G0287629(rbx1)
DPPDICPUDRAFT_88388
EHIEHI_151630(2.t00108)
EDIEDI_254030
EIVEIN_381390 EIN_381400
ACANACA1_368020
PFAPF3D7_0319100
PFDPFDG_02979
PFHPFHG_00876
PREIPRSY57_0318400
PGABPGSY75_0319100
PYOPY17X_0809400
PCBPCHAS_080650(PC000269.01.0)
PBEPBANKA_0806200
PVVPVVCY_1000790
PKNPKNH_0822400
PVXPVX_095280
PCYPCYB_083070
TANTA10565
TPVTP04_0669
TOTTOT_040000249
BBOBBOV_III007590(17.m07664)
BMICBmR1_04g06125
BBIGBBBOND_0306580
CPVcgd8_930
CHOChro.80112
TGOTGME49_213690
TETTTHERM_00313710
PTMGSPATT00005494001 GSPATT00011131001 GSPATT00021114001 GSPATT00023020001 GSPATT00024170001 GSPATT00030724001
SMINv1.2.005788.t1(symbB.v1.2.005788.t1)
PTIPHATRDRAFT_39090(Rbx1)
FCYFRACYDRAFT_206499
TPSTHAPSDRAFT_40817
NGDNGA_0441600(RBX1)
AAFAURANDRAFT_22764 AURANDRAFT_8889
PIFPITG_01524
PSOJPHYSODRAFT_285454
SPARSPRG_11654
EHXEMIHUDRAFT_358602 EMIHUDRAFT_49116 EMIHUDRAFT_50030
GTTGUITHDRAFT_86348
TBRTb10.70.6035
TBGTbgDal_V5200 TbgDal_X2190 TbgDal_X9640
TCR503965.20 506495.9
LMALMJF_21_0023 LMJF_24_1610
LIFLINJ_21_0040 LINJ_24_1680
LDOLDBPK_210040 LDBPK_241680
LMILMXM_21_0023 LMXM_24_1610
LBZLBRM_21_0040 LBRM_24_1670
LPANLPMP_210030 LPMP_241580
NGRNAEGRDRAFT_5552
TVATVAG_104450 TVAG_104530 TVAG_399840
 » show all
Reference
1  [PMID:18826954]
  Authors
Kim AY, Bommelje CC, Lee BE, Yonekawa Y, Choi L, Morris LG, Huang G, Kaufman A, Ryan RJ, Hao B, Ramanathan Y, Singh B
  Title
SCCRO (DCUN1D1) is an essential component of the E3 complex for neddylation.
  Journal
J Biol Chem 283:33211-20 (2008)
DOI:10.1074/jbc.M804440200
Reference
2  [PMID:18206966]
  Authors
Kurz T, Chou YC, Willems AR, Meyer-Schaller N, Hecht ML, Tyers M, Peter M, Sicheri F
  Title
Dcn1 functions as a scaffold-type E3 ligase for cullin neddylation.
  Journal
Mol Cell 29:23-35 (2008)
DOI:10.1016/j.molcel.2007.12.012
Reference
3  [PMID:20832729]
  Authors
Scott DC, Monda JK, Grace CR, Duda DM, Kriwacki RW, Kurz T, Schulman BA
  Title
A dual E3 mechanism for Rub1 ligation to Cdc53.
  Journal
Mol Cell 39:784-96 (2010)
DOI:10.1016/j.molcel.2010.08.030
Reference
4  [PMID:24949976]
  Authors
Scott DC, Sviderskiy VO, Monda JK, Lydeard JR, Cho SE, Harper JW, Schulman BA
  Title
Structure of a RING E3 trapped in action reveals ligation mechanism for the ubiquitin-like protein NEDD8.
  Journal
Cell 157:1671-84 (2014)
DOI:10.1016/j.cell.2014.04.037
Reference
5  [PMID:23201271]
  Authors
Monda JK, Scott DC, Miller DJ, Lydeard J, King D, Harper JW, Bennett EJ, Schulman BA
  Title
Structural conservation of distinctive N-terminal acetylation-dependent interactions across a family of mammalian NEDD8 ligation enzymes.
  Journal
Structure 21:42-53 (2013)
DOI:10.1016/j.str.2012.10.013
Other DBs
ExplorEnz - The Enzyme Database: 2.3.2.32
IUBMB Enzyme Nomenclature: 2.3.2.32
ExPASy - ENZYME nomenclature database: 2.3.2.32
BRENDA, the Enzyme Database: 2.3.2.32
LinkDB

DBGET integrated database retrieval system