KEGG   ENZYME: 2.4.1.170
Entry
EC 2.4.1.170                Enzyme                                 
Name
isoflavone 7-O-glucosyltransferase;
uridine diphosphoglucose-isoflavone 7-O-glucosyltransferase;
UDPglucose-favonoid 7-O-glucosyltransferase;
UDPglucose:isoflavone 7-O-glucosyltransferase
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
Sysname
UDP-glucose:isoflavone 7-O-beta-D-glucosyltransferase
Reaction(IUBMB)
UDP-glucose + an isoflavone = UDP + an isoflavone 7-O-beta-D-glucoside [RN:R07332]
Reaction(KEGG)
Substrate
UDP-glucose [CPD:C00029];
isoflavone [CPD:C00799]
Product
UDP [CPD:C00015];
isoflavone 7-O-beta-D-glucoside [CPD:C04074]
Comment
The 4'-methoxy isoflavones biochanin A and formononetin and, more slowly, the 4'-hydroxyisoflavones genistein and daidzein, can act as acceptors. The enzyme does not act on isoflavanones, flavones, flavanones, flavanols or coumarins.
History
EC 2.4.1.170 created 1989
Pathway
ec00943  Isoflavonoid biosynthesis
ec01110  Biosynthesis of secondary metabolites
Orthology
K13263  isoflavone 7-O-glucosyltransferase
Genes
GMX100101902(IF7GT) 100776806(UGT8) 100777343(UGT7)
GSJ114389413 114389415 114390098
PVUPHAVU_004G104200g
VRA106763357
VAR108344639(AdGt-5) 108344857
VUN114181375 114181452
APRC113867100
Reference
1  [PMID:6458246]
  Authors
Koster J, Barz W.
  Title
UDP-glucose:isoflavone 7-O-glucosyltransferase from roots of chick pea (Cicer arietinum L.).
  Journal
Arch Biochem Biophys 212:98-104 (1981)
DOI:10.1016/0003-9861(81)90347-7
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.170
IUBMB Enzyme Nomenclature: 2.4.1.170
ExPASy - ENZYME nomenclature database: 2.4.1.170
BRENDA, the Enzyme Database: 2.4.1.170
CAS: 97089-62-8
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