Entry
Name
1,2-diacylglycerol 3-alpha-glucosyltransferase;
mgs (gene name);
UDP-glucose:diacylglycerol glucosyltransferase;
UDP-glucose:1,2-diacylglycerol glucosyltransferase;
uridine diphosphoglucose-diacylglycerol glucosyltransferase;
UDP-glucose-diacylglycerol glucosyltransferase;
UDP-glucose:1,2-diacylglycerol 3-D-glucosyltransferase;
UDP-glucose:1,2-diacyl-sn-glycerol 3-D-glucosyltransferase;
1,2-diacylglycerol 3-glucosyltransferase (ambiguous)
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
BRITE hierarchy
Sysname
UDP-alpha-D-glucose:1,2-diacyl-sn-glycerol 3-alpha-D-glucosyltransferase
Reaction(IUBMB)
UDP-alpha-D-glucose + a 1,2-diacyl-sn-glycerol = UDP + a 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol [RN:
R10850 R12902 ]
Reaction(KEGG)
Substrate
UDP-alpha-D-glucose [CPD:
C00029 ];
1,2-diacyl-sn-glycerol [CPD:
C00641 ]
Product
UDP [CPD:
C00015 ];
1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol [CPD:
C06364 ]
Comment
The enzyme from the bacterium Acholeplasma laidlawii, which lacks a cell wall, produces the major non-bilayer lipid in the organism. The enzyme from the bacterium Agrobacterium tumefaciens acts under phosphate deprivation, generating glycolipids as surrogates for phospholipids. The enzyme belongs to the GT4 family of configuration-retaining glycosyltransferases. Many diacylglycerols with long-chain acyl groups can act as acceptors. cf. EC
2.4.1.336 , monoglucosyldiacylglycerol synthase.
History
EC 2.4.1.337 created 2015
Pathway
Orthology
K19002 1,2-diacylglycerol 3-alpha-glucosyltransferase
K27597 1,2-diacylglycerol 3-alpha-glucosyltransferase/glucuronosyltransferase
Genes
PAEB : NCGM1900_3080(grtA)
PCQ : PcP3B5_44980(mgtA_2)
LCJ : NCTC11976_00592(mgtA_1)
MSZE : MSZNOR_1382 MSZNOR_1448
MPIN : LGT42_002320 LGT42_003665 LGT42_004010
NWR : E3U44_00960 E3U44_10035
TLR : Thiosp_03885(mgtA_3)
TFRI : Thiofri_00856(mgtA_1) Thiofri_03220(epsD)
TWG : Thiowin_02331(mgtA_2)
MFRA : D5125_10120 D5125_10160
HAK : KO116_01620 KO116_03650
HPRO : LMS44_03150 LMS44_15130
HALF : QEN58_03030 QEN58_12850
HAAH : HALA3H3_200069 HALA3H3_750013
HABD : OM794_03370 OM794_14565
HAFN : KF947_03905 KF947_14990
HAAZ : HaloA020_00530 HaloA020_01670
HSPE : IT895_03090 IT895_10265 IT895_10295
HSR : HSBAA_09480 HSBAA_44290
HPIZ : GYM47_12155 GYM47_12720
HNP : SR894_02755 SR894_13380
HTT : HZS52_00715 HZS52_12990
HMD : CTT34_12870 CTT34_13415
REH : H16_A1028(h16_A1028)
BTRM : SAMEA390648701401(mgtA_2)
AXX : ERS451415_05977(mgtA_2)
AIS : BUW96_24410 BUW96_24700
ACIP : CBP36_03040 CBP36_12875
ACIS : CBP35_06045 CBP35_15900
OTK : C6570_15650 C6570_15675
OTD : J1M35_06730 J1M35_15420
LIM : L103DPR2_01077(mgtA)
LIH : L63ED372_02124(mgtA_2)
METP : C1M51_00970 C1M51_04655
PCAZ : ACMDW7_04920 ACMDW7_04955
BBAG : E1O_09070 E1O_30200
MUV : FIT94_04605 FIT94_04635
MEDZ : MTDW_17180 MTDW_18130
URU : DSM104443_03146(mgtA_1) DSM104443_03293(mgtA_2)
UPL : DSM104440_02640(mgtA)
BEBA : BWI17_10530 BWI17_11180
AMIH : CO731_02433(mgtA_1)
RBS : RHODOSMS8_02330(mgtA)
HOE : IMCC20628_00545 IMCC20628_00552
BJA : bll5903(bll5903) bll6635(bll6635) bll8163(gtrA)
BJU : BJ6T_27900 BJ6T_38090
BJP : RN69_13625 RN69_18470
BRC : BCCGELA001_09815 BCCGELA001_25120
BRAD : BF49_5014 BF49_5742
BIC : LMTR13_28160 LMTR13_31725
BRK : CWS35_07480 CWS35_31445 CWS35_33820
BOT : CIT37_21435 CIT37_24785
BRQ : CIT40_21465 CIT40_25050
BGQ : X265_10035 X265_14185
BGZ : XH91_08950 XH91_11975
BSYM : CIT39_20795 CIT39_24015
BBET : F8237_23540 F8237_26865
BARH : WN72_32735 WN72_37965
BVZ : BRAD3257_2617 BRAD3257_3212
BEL : BE61_05080 BE61_35660 BE61_41120
BDG : LPJ38_14210 LPJ38_31535
BSEP : HAP48_0003115 HAP48_0047185
BQB : J4P68_0006380 J4P68_0008835 J4P68_0017930
BSEI : KMZ68_18595 KMZ68_21150
BBAN : J4G43_035335 J4G43_039385
BCAN : BcanWSM471_26185 BcanWSM471_29245
BAUT : QA635_13215 QA635_15960
BBRA : QA636_13040 QA636_16470
BGK : IC762_24470 IC762_26965
BCOU : IC761_08790 IC761_12170
BPAH : QA639_29105 QA639_31565
BROS : QUH67_25505 QUH67_28535
BRAZ : LRP30_27185 LRP30_35310
BRAY : ML401_22725 ML401_27120
BRAI : FJV43_05450 FJV43_09585
BRAA : NL528_31015 NL528_35185
BLUP : AB3L03_26065 AB3L03_30455
RPX : Rpdx1_3722 Rpdx1_4227
MAQU : Maq22A_c09225(rfaG)
MPOL : RZS28_09655 RZS28_13160 RZS28_17095
BBAI : CU048_02510 CU048_13605
PLEO : OHA_1_04372(mgtA_2)
MAAD : AZF01_03935 AZF01_18345
AUZ : Sa4125_26460 Sa4125_39390
LABR : CHH27_05875 CHH27_10415
LABP : FJ695_09780 FJ695_13285 FJ695_23040
RPOP : K1718_10860 K1718_14110
CAUB : AMEJIAPC_00378(mgtA)
BVY : NCTC9239_02839(mgtA)
BREN : KKHFBJBL_02495(mgtA)
ASTM : MMA231_00354(mshA_1)
TSV : DSM104635_03310(mgtA)
SPAG : sphantq_03179(mgtA_2)
SFLA : SPHFLASMR4Y_00452(mgtA)
RPM : RSPPHO_00472 RSPPHO_01663
MGY : MGMSRv2__2852 MGMSRv2__4110
MGRY : MSR1_22900(mgtA_1) MSR1_35040(mgtA_3)
MAGN : WV31_01585 WV31_13655
AFH : GL267_001640 GL267_006845
TBE : Trebr_0432 Trebr_0970
SFC : Spiaf_0092 Spiaf_0093
SGP : SpiGrapes_0163 SpiGrapes_0367 SpiGrapes_0753 SpiGrapes_1078 SpiGrapes_2889
CABY : Cabys_1107 Cabys_2433
DTH : DICTH_0026 DICTH_0815
BSM : BSM4216_3294 BSM4216_3566
LGZ : NCTC10812_02558(pimB_3)
SVB : NCTC12167_00600(ugtP)
SMEN : SAMEA4412692_0129(mgtA)
SFER : NCTC12278_01377(mgtA)
SCAI : NCTC12191_00029(mgtA)
SPSU : NCTC13786_01835(pimB_1)
SPOC : NCTC10925_01327(mgtA)
SAUP : NCTC3168_01326(mgtA_3)
SURN : NCTC13766_01601(mgtA)
SVF : NCTC3166_01422(mgtA_1)
SMIE : NCTC11169_00647(mgtA)
LAI : LAC30SC_02290 LAC30SC_05115
LAY : LAB52_02175 LAB52_05070
LAMY : B1745_05795 B1745_07745
LUU : H4B44_02850 H4B44_10920
ECEC : NCTC12421_01432(pimB_2)
AUI : APT62_02240 APT62_06805
AVS : AWM76_03390 AWM76_08155
CML : BN424_2419(rfaG) BN424_2460(rfaG-2)
CAE : SMB_G2571(mgtA) SMB_G3635
CMAH : C1I91_09965 C1I91_15085
CRW : CROST_032050 CROST_045080
CFB : CLFE_003020 CLFE_031970
CAUN : CLAUR_029980 CLAUR_044230
HHW : NCTC503_01926(mgtA_2)
CSS : Cst_c07770 Cst_c17340
DGI : Desgi_1986 Desgi_4030
BPRO : PMF13cell1_02046 PMF13cell1_04337 PMF13cell1_04561
BCOC : BLCOC_10920(mshA) BLCOC_35590
LBW : C3V36_09360 C3V36_10780
CLE : Clole_0152 Clole_2186
CEW : EKH84_03935 EKH84_13115
PIV : NCTC13079_00132(mgtA)
MBP : MBSPM3_v1c0110(mgs) MBSPM3_v1c0120(mgs)
RPHY : RP166_0110(rfaG) RP166_0120(rfaG)
PASE : QN326_00110 QN326_00120
AHK : NCTC10172_00220(mgtA_1) NCTC10172_00268(mgtA_2)
NAD : NCTC11293_03530(pimA_1)
MFOL : DXT68_08870 DXT68_15565
ORN : DV701_07875 DV701_15600
DCO : SAMEA4475696_0403(cotSA)
PPC : HMPREF9154_0269 HMPREF9154_1531
TES : BW730_00425 BW730_05100
TEZ : BKM78_00290 BKM78_09055
TDF : H9L22_05890 H9L22_15370 H9L22_16430
TLA : TLA_TLA_00060 TLA_TLA_01828(mgs)
PRV : G7070_06030 G7070_10065
NGV : CDO52_05980 CDO52_21295
STRR : EKD16_02860(mgs) EKD16_06985(pimB4)
AWS : ACN3XK_00875 ACN3XK_64680
PRY : Prubr_28730 Prubr_33830
AIR : AIF0345_0386 AIF0345_3247
ASLA : NCTC11923_01626(pimB_3)
AVC : NCTC10951_00474(mgtA)
CYC : PCC7424_5786 PCC7424_5790
CCZ : CCALI_02181 CCALI_02532
DMR : Deima_0594 Deima_2949
DGO : DGo_CA2214 DGo_CA2495
DSW : QR90_00770 QR90_08125
DEIN : DAAJ005_08760 DAAJ005_16600
DGA : DEGR_04410 DEGR_09070
BBGW : UT28_C0001G0809(mgtA)
» show all
Taxonomy
Reference
Authors
Karlsson OP, Dahlqvist A, Vikstrom S, Wieslander A.
Title
Lipid dependence and basic kinetics of the purified 1,2-diacylglycerol 3-glucosyltransferase from membranes of Acholeplasma laidlawii.
Journal
Reference
Authors
Li L, Storm P, Karlsson OP, Berg S, Wieslander A
Title
Irreversible binding and activity control of the 1,2-diacylglycerol 3-glucosyltransferase from Acholeplasma laidlawii at an anionic lipid bilayer surface.
Journal
Reference
Authors
Berg S, Edman M, Li L, Wikstrom M, Wieslander A.
Title
Sequence properties of the 1,2-diacylglycerol 3-glucosyltransferase from Acholeplasma laidlawii membranes. Recognition of a large group of lipid glycosyltransferases in eubacteria and archaea.
Journal
Sequence
Reference
Authors
Semeniuk A, Sohlenkamp C, Duda K, Holzl G
Title
A bifunctional glycosyltransferase from Agrobacterium tumefaciens synthesizes monoglucosyl and glucuronosyl diacylglycerol under phosphate deprivation.
Journal
Sequence
Other DBs
ExPASy - ENZYME nomenclature database: 2.4.1.337
LinkDB
All DBs