Entry |
|
Name |
nicotinamide phosphoribosyltransferase;
NMN pyrophosphorylase;
nicotinamide mononucleotide pyrophosphorylase;
nicotinamide mononucleotide synthetase;
NMN synthetase;
nicotinamide-nucleotide:diphosphate phospho-alpha-D-ribosyltransferase
|
Class |
Transferases;
Glycosyltransferases;
Pentosyltransferases
|
Sysname |
nicotinamide-D-ribonucleotide:diphosphate phospho-alpha-D-ribosyltransferase
|
Reaction(IUBMB) |
nicotinamide D-ribonucleotide + diphosphate = nicotinamide + 5-phospho-alpha-D-ribose 1-diphosphate [RN: R01271]
|
Reaction(KEGG) |
|
Substrate |
nicotinamide D-ribonucleotide [CPD: C00455];
diphosphate [CPD: C00013]
|
Product |
nicotinamide [CPD: C00153];
5-phospho-alpha-D-ribose 1-diphosphate [CPD: C00119]
|
History |
EC 2.4.2.12 created 1961
|
Pathway |
ec00760 | Nicotinate and nicotinamide metabolism |
|
Orthology |
K03462 | nicotinamide phosphoribosyltransferase |
|
Genes |
PTR: | 463648(NAMPT) 741031 |
CJC: | 100393546(NAMPT) 100402410 |
PLEU: | 114688826 114708446(Nampt) |
NGI: | 103732185(Nampt) 103743693 |
ZCA: | 113912041(NAMPT) 113939659 |
NSU: | 110574280(NAMPT) 110593898 |
TVP: | 118844560 118850298(NAMPT) |
XLA: | 398502(nampt.S) 735059(nampt.L) |
DRE: | 100330160(nampt1) 324211(nampt2) |
SRX: | 107705339 107718548 107728616 107739284 |
SANH: | 107656408 107658946 107696850 |
SGH: | 107550476 107583940(nampt) 107590159 |
CCAR: | 109047414 109064254 109066351 |
CAUA: | 113047893 113055252 113064575 113067909 113076104 113092089 113101511 |
CGIB: | 127956871 127968168 127978869 128022393 |
PTET: | 122342815(nampt1) 122354539(nampt2) |
LROH: | 127164051(nampt1) 127173147(nampt2) |
OMC: | 131539219(nampt1) 131549701(nampt2) |
PPRM: | 120470956(nampt1) 120480461(nampt2) |
RKG: | 130075956(nampt2) 130080053(nampt1) |
MAMB: | 125245168(nampt1) 125256331(nampt2) |
CIDE: | 127510741 127522040 |
CERY: | 137021589(nampt2) 137024183(nampt1) |
MASI: | 127426416 127427960 127435286 127436530 |
TROS: | 130548217(nampt1) 130571476(nampt2) |
TDW: | 130410398(nampt2) 130420917(nampt1) |
MANU: | 129428157(nampt2) 129431866(nampt1) |
IPU: | 108255025(nampt2) 108279799(nampt1) |
IFU: | 128623428(nampt1) 128625074(nampt2) |
PHYP: | 113532099(nampt) 113539570 |
SMEO: | 124401159(nampt1) 124402429(nampt2) |
TFD: | 113645426(nampt1) 113661848(nampt2) |
TVC: | 132837890(nampt2) 132858866(nampt1) |
TRN: | 134301523(nampt2) 134312550(nampt1) |
AMEX: | 103041462(nampt2) 103042355(nampt1) |
CMAO: | 118799353(nampt2) 118812667(nampt1) |
EEE: | 113575803(nampt) 113587333 |
CHAR: | 105896742(nampt1) 105912295(nampt2) |
LCO: | 104922484 104934037(nampt) |
TBEN: | 117483120(nampt1) 117493295(nampt2) |
CGOB: | 115008611 115028197(nampt) |
PGEO: | 117446191(nampt2) 117468429(nampt1) |
GACU: | 117557519(nampt2) 117560023(nampt1) |
EMAC: | 134878942(nampt1) 134882706(nampt2) |
ELY: | 117249213(nampt1) 117250801 117257049(nampt2) |
EFO: | 125882713(nampt1) 125885583(nampt2) |
PLEP: | 121952237(nampt2) 121961171(nampt1) |
SLUC: | 116034546(nampt2) 116039784(nampt1) |
ECRA: | 117938391(nampt1) 117943068(nampt2) |
ESP: | 116672787(nampt) 116687964 |
PFLV: | 114549975(nampt) 114554450 |
GAT: | 120817431(nampt1) 120834841(nampt2) |
PPUG: | 119210530(nampt1) 119230014(nampt2) |
AFB: | 129105623(nampt2) 129112232(nampt1) |
CLUM: | 117726247(nampt1) 117730745(nampt2) |
PSWI: | 130200626(nampt1) 130208113(nampt2) |
MSAM: | 119886246(nampt2) 119918255(nampt1) |
SCHU: | 122871073(nampt1) 122883610(nampt2) |
CUD: | 121505386(nampt1) 121506854(nampt2) |
ALAT: | 119021617(nampt2) 119032651(nampt1) |
OLA: | 101156645 101167087(nampt) |
OML: | 112145448(nampt2) 112155898(nampt1) |
CSAI: | 133423793(nampt1) 133449546(nampt2) |
XMA: | 102220339 102232015(nampt) |
XCO: | 114135936 114161249(nampt) |
XHE: | 116710812 116737127(nampt) |
PRET: | 103459433(nampt) 103465472 |
PFOR: | 103129527 103150295 103156950(nampt) |
PLAI: | 106946294 106959170(nampt) |
PMEI: | 106905456 106905851 106932544 |
GAF: | 122826581(nampt1) 122833697(nampt2) |
PPRL: | 129358427(nampt2) 129375604(nampt1) |
CTUL: | 119772608(nampt2) 119776346(nampt1) |
KMR: | 108235115(nampt1) 108240353(nampt2) |
ALIM: | 106530702 106535825(nampt) |
AOCE: | 111576719 111578827(nampt) |
MCEP: | 125000006(nampt1) 125007051(nampt2) |
POV: | 109632705(nampt) 109640359 |
SSEN: | 122766704(nampt1) 122768439(nampt2) |
HHIP: | 117757215(nampt1) 117762258(nampt2) |
HSP: | 118101554(nampt1) 118104925(nampt2) |
PPLT: | 128428587(nampt1) 128456214(nampt2) |
SMAU: | 118309327(nampt2) 118319349(nampt1) |
LCF: | 108873533(nampt2) 108888920(nampt1) |
SDU: | 111221675 111224669(nampt) |
SLAL: | 111663698(nampt) 111668643 |
XGL: | 120804225(nampt1) 120807423(nampt2) |
HCQ: | 109513519(nampt) 109514513 |
BPEC: | 110161662(nampt) 110165776 |
MALB: | 109951434 109959864(nampt) |
BSPL: | 114855563(nampt2) 114862336(nampt1) |
SJO: | 128353440(nampt1) 128356211(nampt2) |
SASA: | 100380855(nampt) 106561705(nampt) 106565851 106609207 |
STRU: | 115180000 115197667 115198747 115207669 |
OTW: | 112214341(nampt1) 112216868 112219097(nampt2) 112238280 |
OMY: | 110490269 110494490(nampt2) 110500207 110500466 |
OGO: | 123994644 124003681(nampt2) 124014313 124032262 |
ONE: | 115106959 115116225 115133159 115143310 |
OKI: | 109864323 109867082 109896755 109896974 |
OKE: | 118373568 118374842 118388437(nampt2) 118392341 |
SNH: | 120032167 120049894 120059900(nampt2) 120066497 |
CCLU: | 121531558 121543662 121546224(nampt1) 121574946(nampt2) |
ELS: | 105017246 105025655(nampt) 105029720 |
SFM: | 108918794(nampt) 108923454 108931584 |
PKI: | 111834574 111835587 111857433(nampt) |
AANG: | 118211552(nampt2) 118219008 118231476(nampt1) |
LOC: | 102687550 102689605(nampt) |
PSPA: | 121297879 121318311 121319793(nampt1) 121329382 |
ARUT: | 117414206 117415973(nampt1) 117419927 117972040 |
PSEX: | 120533993(nampt1) 120540093(nampt2) |
CMK: | 103179768(nampt2) 103186243(nampt1) |
CPLA: | 122559257(nampt2) 122559519(nampt1) |
HOC: | 132822481(nampt2) 132824988(nampt1) |
LERI: | 129704485(nampt2) 129706206(nampt1) |
PMRN: | 116947429 116952276 |
LPIC: | 129257887 129257888 |
PJA: | 122250105 122256723 122258658 |
PCHN: | 125031477 125031535 |
PMOO: | 119591793 119593412 119593700 |
HAME: | 121869935 121869936 121873813 121873830 |
PCLA: | 123745860 123746029 123752573 123763149 |
CQD: | 128685590 128694635 128696732 |
PTRU: | 123505608 123505669 123505762 |
ESN: | 126980698 127001507 127001678 |
MNZ: | 135204962 135208018 135209624 |
RSAN: | 119397675 119397676 |
LPOL: | 106469485 106469665 |
MCAF: | 127727212 127727213 |
RPHI: | 132720979 132734641 |
ATEN: | 116302032 116308254 |
AAF: | AURANDRAFT_29036 AURANDRAFT_39495 |
HDU: | HD_1447(nadV1) HD_1455(nadV2) |
XPH: | XppCFBP6546_08205(XppCFBP6546P_08205) |
PSYC: | DABAL43B_2513(pncB3) |
MBAH: | HYN46_07910 HYN46_15680 |
SCAA: | TUM17387_03530(nadV) |
MTHD: | A3224_00620 A3224_08185 |
MII: | BTJ40_00545 BTJ40_19890 |
MISZ: | MishRS11D_10020(pbeF) |
PBRY: | NDK50_10735 NDK50_27890 |
AVV: | RvVAT039_17690(pbeF) |
AVF: | RvVAR031_04830(pbeF) |
METG: | HT051_05405 HT051_05475 |
CFV: | CFVI03293_0021(nadV) |
CAMP: | CFT03427_0021(nadV) |
CAMZ: | CVIC12175_1622(nadV) |
CGEL: | psyc5s11_25820(nadV) |
MSAK: | MSAS_02650(pbeF_1) MSAS_08820 MSAS_13980(pbeF_2) MSAS_13990(pbeF_3) MSAS_14080(pbeF_4) |
MPAA: | MKK62_18000 MKK62_18005 MKK62_18040 |
GJI: | H1R19_00415 H1R19_20255 |
FSB: | GCM10025867_12290(nadV) GCM10025867_48420 |
PDX: | Psed_2146 Psed_2158 Psed_2182 |
PAUT: | Pdca_09570(pbeF_1) Pdca_20140(pbeF_2) Pdca_20850(pbeF_3) |
SYY: | SYNGTS_2731(slr0788) |
SYT: | SYNGTI_2730(slr0788) |
SYS: | SYNPCCN_2729(slr0788) |
SYQ: | SYNPCCP_2729(slr0788) |
MTAI: | Mtai_v1c02500(pncB) |
ATK: | AUTU_01160(nadV) AUTU_17910(pbeF) |
» show all
|
Reference |
|
Authors |
PREISS J, HANDLER P. |
Title |
Enzymatic synthesis of nicotinamide mononucleotide. |
Journal |
J Biol Chem 225:759-70 (1957) |
Other DBs |
ExplorEnz - The Enzyme Database: | 2.4.2.12 |
ExPASy - ENZYME nomenclature database: | 2.4.2.12 |
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LinkDB |
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