Entry
Name
S-sulfo-L-cysteine synthase (O-acetyl-L-serine-dependent);
cysteine synthase B;
cysM (gene name);
CS26 (gene name)
Class
Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
BRITE hierarchy
Sysname
O-acetyl-L-serine:thiosulfate 2-amino-2-carboxyethyltransferase
Reaction(IUBMB)
O-acetyl-L-serine + thiosulfate = S-sulfo-L-cysteine + acetate [RN:
R03132 ]
Reaction(KEGG)
Substrate
Product
Comment
In plants, the activity is catalysed by a chloroplastic enzyme that plays an important role in chloroplast function and is essential for light-dependent redox regulation within the chloroplast. The bacterial enzyme also catalyses the activity of EC
2.5.1.47 , cysteine synthase. cf. EC
2.8.5.1 , S-sulfo-L-cysteine synthase (3-phospho-L-serine-dependent).
History
EC 2.5.1.144 created 2018
Pathway
ec00270 Cysteine and methionine metabolism
Orthology
K12339 S-sulfo-L-cysteine synthase (O-acetyl-L-serine-dependent)
K22846 S-sulfo-L-cysteine synthase (O-acetyl-L-serine-dependent)
Genes
CSAT : 104744457 104744525 104763989 104788662
HSYR : 120113880 120153904
APRC : 113860942 113862220
TPRA : 123891629 123920746
MSYL : 126593464 126600109
CPEP : 111785878 111791892
PSOM : 113310566 113321748
TAES : 123062394 123071176 123079538
MFLO : 136450510 136456732 136460058
PVIR : 120672803 120708446
ECOO : ECRM13514_3246(cysM)
ECOH : ECRM13516_3107(cysM)
ELR : ECO55CA74_14610(cysM)
ECW : EcE24377A_2707(cysM)
ECOA : APECO78_15835(cysM)
EDJ : ECDH1ME8569_2355(cysM)
ECOI : ECOPMV1_02623(cysM)
SEM : STMDT12_C24590(cysM)
SETC : CFSAN001921_04565(cysM)
SEEN : SE451236_18425(cysM)
SENH : CFSAN002069_19555(cysM)
SEEH : SEEH1578_21525(cysM)
SENJ : CFSAN001992_21375(cysM)
SEEC : CFSAN002050_19150(cysM)
SEEB : SEEB0189_007360(cysM)
SENC : SEET0819_19655(cysM)
KPE : KPK_1370(cysM) KPK_1752
KPK : A593_01915 A593_04105(cysM)
KVD : KR75_01405 KR75_25915
KVQ : SP68_06070 SP68_07925
KOX : KOX_18690 KOX_26885(cysM)
KOY : J415_10740(cysM) J415_18930
KOM : HR38_17055 HR38_25045(cysM)
KOK : KONIH1_12480 KONIH1_21125(cysM)
REE : electrica_01350(cysM)
RON : TE10_18740 TE10_20800(cysM)
CLAP : NCTC11466_01171(cysM)
KIE : NCTC12125_00278(cysM)
BAGE : BADSM9389_11490(cysM)
AHN : NCTC12129_01401(cysM_2)
MPHG : MPHASIOC01_002730(cysM)
YPG : YpAngola_A2765(cysM)
YPI : YpsIP31758_1303(cysM)
YKI : HRD70_10830(cysM) HRD70_18000
SMW : SMWW4_v1c35640(cysM)
SERS : SERRSCBI_17320(cysM)
SFJ : SAMEA4384070_3583(cysM)
SOF : NCTC11214_03214(cysM)
SSAR : SSARUM_003440(cysM)
GQU : AWC35_07105 AWC35_18835(cysM)
PAQU : DMB82_0016360(cysM)
PPOO : LW347_02460 LW347_04200(cysM)
PACB : M9782_04515 M9782_06475(cysM)
PARL : PEC302110_07800(cysM) PEC302110_35360
DAQ : DAQ1742_00860(cysM) DAQ1742_02336
DIC : Dpoa569_003151(cysM)
BNG : EH206_14245 EH206_18075(cysM)
TCI : A7K98_12380 A7K98_14415
TPTY : NCTC11468_02701(cysM_2)
PHEI : NCTC12003_01469(cysM)
PRJ : NCTC6933_02487(cysM)
LRI : NCTC12151_01012(cysM)
VAU : VANGNB10_cI0442c(cysM)
VPL : SA104470976_02191(cysM_2)
PAEB : NCGM1900_1786(cysM)
PPUD : DW66_1228 DW66_1590
PVD : CFBP1590__1567(cysM)
PPRC : PFLCHA0_c45210(cysM)
PMUD : NCTC8068_03866(cysM)
PFW : PF1751_v1c40030(cysM)
PPUU : PputUW4_04107(cysM)
PTRT : HU722_0021195(cysM)
PTAE : NCTC10697_01135(cysM)
PPSE : BN5_1558(cysM1) BN5_1910(cysM3)
PSYC : DABAL43B_0442(cysM)
MCAT : MC25239_00185(cysM)
MCUN : NCTC10297_00621(cysM)
MEEF : JWZ97_16430(cysM) JWZ97_19495(cysM)
MISZ : MishRS11D_16830(cysM)
TIB : THMIRHAM_12490(cysM)
TSE : THMIRHAS_12010(cysM)
TFRI : Thiofri_03696(cysM)
TNI : TVNIR_0833(cysM_[H])
GAI : IMCC3135_11790(cysM)
THIC : TspCOW1_15840(cysM)
HAAH : HALA3H3_940005(cysM)
ALCA : ASALC70_03827(cysM)
AEL : NCTC12917_01362(cysM_2)
CCAH : DWG20_09845 DWG20_14615
BMV : BMASAVP1_A2562(cysM)
BML : BMA10229_A0938(cysM)
BPM : BURPS1710b_2984(cysM)
BPL : BURPS1106A_2937(cysM)
BFN : OI25_2427(cysM) OI25_7456(cysM)
PLAD : PPGU16_08250(cysM_1)
POLT : TUM22923_12750(cysM)
PLG : NCTC10937_04045(cysM)
LMIR : NCTC12852_01258(cysM)
CABA : SBC2_26740(cysM_1) SBC2_57030(cysM_2) SBC2_72250(cysM_3)
BUO : BRPE64_ACDS20580(cysM)
BTRM : SAMEA390648703838(cysM_2)
AXX : ERS451415_01618(cysM)
LIM : L103DPR2_02463(cysM)
LIH : L63ED372_02366(cysM)
SMIO : CATMQ487_47520(cysM)
URU : DSM104443_02625(cysM)
UPL : DSM104440_02348(cysM)
ARES : IWH25_03190 IWH25_10065(cysM)
APET : ToN1_15200(cysM) ToN1_48830
AZA : AZKH_2772(cysM) AZKH_3550(cysM)
AZD : CDA09_12025 CDA09_17530
THAG : CKCBHOJB_01314(cysM)
FPHO : SHINM1_014200(cysM)
GBN : GEOBRER4_10410(cysM)
AORY : AMOR_01730 AMOR_46360
SAMY : DB32_003077 DB32_003961
ACOU : A5CBH24_06840(cysM)
ADA : A5CPEGH6_16790(cysM)
CBAM : PIECOFPK_01108(cysM)
SMIZ : 4412673_03140(cysM)
SDJ : NCTC13534_04450(cysM_2)
STHA : NCTC11429_02614(cysM)
RHOZ : GXP67_32725(cysM) GXP67_36225
PSEZ : HME7025_02459(cysK)
REK : N6H18_12475(cysM) N6H18_12775
AALG : AREALGSMS7_04294(cysM)
PTAN : CRYO30217_01637(cysM)
NFR : ERS450000_01532(cysK_1)
SXT : KPP03845_101366(cysM_1)
DLY : Dehly_0236 Dehly_1596
LOKI : Lokiarch_29980(cysM_1) Lokiarch_30500(cysM_2) Lokiarch_42820(cysK_2)
» show all
Taxonomy
Reference
Authors
Hensel G, Truper HG
Title
O-Acetylserine sulfhydrylase and S-sulfocysteine synthase activities of Rhodospirillum tenue.
Journal
Reference
Authors
Nakamura T, Iwahashi H, Eguchi Y
Title
Enzymatic proof for the identity of the S-sulfocysteine synthase and cysteine synthase B of Salmonella typhimurium.
Journal
Reference
Authors
Bermudez MA, Paez-Ochoa MA, Gotor C, Romero LC
Title
Arabidopsis S-sulfocysteine synthase activity is essential for chloroplast function and long-day light-dependent redox control.
Journal
Sequence
Reference
Authors
Bermudez MA, Galmes J, Moreno I, Mullineaux PM, Gotor C, Romero LC
Title
Photosynthetic adaptation to length of day is dependent on S-sulfocysteine synthase activity in the thylakoid lumen.
Journal
Sequence
Reference
Authors
Gotor C, Romero LC
Title
S-sulfocysteine synthase function in sensing chloroplast redox status.
Journal
Other DBs
ExPASy - ENZYME nomenclature database: 2.5.1.144
LinkDB
All DBs