Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
BRITE hierarchy

O-acetyl-L-homoserine:methanethiol 3-amino-3-carboxypropyltransferase

O-acetyl-L-homoserine + methanethiol = L-methionine + acetate [RN:R00651]

R00651;
(other) R01287 R04859
Reaction

O-acetyl-L-homoserine [CPD:C01077];
methanethiol [CPD:C00409]

Also reacts with other thiols and H2S, producing homocysteine or thioethers. The name methionine synthase is more commonly applied to EC 2.1.1.13, methionine synthase. The enzyme from baker's yeast also catalyses the reaction of EC 2.5.1.47 cysteine synthase, but more slowly.

EC 2.5.1.49 created 1972 as EC 4.2.99.10, transferred 2002 to EC 2.5.1.49