KEGG ENZYME: 2.7.1.134

ENZYME: 2.7.1.134

Entry

EC 2.7.1.134                Enzyme

Name

inositol-tetrakisphosphate 1-kinase;
1D-myo-inositol-tetrakisphosphate 1-kinase;
inositol-trisphosphate 6-kinase;
1D-myo-inositol-trisphosphate 6-kinase;
ATP:1D-myo-inositol-1,3,4-trisphosphate 6-phosphotransferase;
inositol-trisphosphate 5-kinase;
1D-myo-inositol-trisphosphate 5-kinase;
ATP:1D-myo-inositol-1,3,4-trisphosphate 5-phosphotransferase

Class

Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor

Sysname

ATP:1D-myo-inositol-3,4,5,6-tetrakisphosphate 1-phosphotransferase

Reaction(IUBMB)

ATP + 1D-myo-inositol 3,4,5,6-tetrakisphosphate = ADP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate [RN:R03479]

Reaction(KEGG)

R03479

Substrate

ATP [CPD:C00002];
1D-myo-inositol 3,4,5,6-tetrakisphosphate [CPD:C04520]

Product

ADP [CPD:C00008];
1D-myo-inositol 1,3,4,5,6-pentakisphosphate [CPD:C01284]

Comment

This enzyme also phosphorylates Ins(1,3,4)P3 on O-5 and O-6. The phosphotransfer from ATP to either inositol 1,3,4-trisphosphate or inositol 3,4,5,6-tetrakisphosphate appears to be freely reversible to the extent that the enzyme can act like an inositol polyphosphate phosphatase in the presence of ADP. It can also catalyse an isomerization between Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 in the presence of ADP. The enzymes from animals and plants also have the activity of EC 2.7.1.159, inositol-1,3,4-trisphosphate 5/6-kinase.

History

EC 2.7.1.134 created 1990, (EC 2.7.1.133 created 1989, incorporated 2002, EC 2.7.1.139 created 1992, incorporated 2002), modified 2002

Pathway

ec00562

Inositol phosphate metabolism

ec01100

Metabolic pathways

Orthology

K00913

inositol-1,3,4-trisphosphate 5/6-kinase / inositol-tetrakisphosphate 1-kinase

Genes

HSA:	3705(ITPK1)

PTR:	453121(ITPK1)

PPS:	100980755(ITPK1)

GGO:	101134664(ITPK1)

PON:	100448118(ITPK1)

PPYG:

129012101(ITPK1)

NLE:	100590495(ITPK1)

HMH:	116456328(ITPK1)

SSYN:

129487503(ITPK1)

MCC:	698756(ITPK1)

MCF:	102119398(ITPK1)

MTHB:

126959672

MNI:	105467527(ITPK1)

CSAB:

103229579(ITPK1)

CATY:

105596596(ITPK1)

PANU:

101022831(ITPK1)

TGE:	112628636(ITPK1)

MLEU:

105547947(ITPK1)

RRO:	104679048(ITPK1)

RBB:	108519106(ITPK1)

TFN:	117071511(ITPK1)

PTEH:

111538240(ITPK1)

CANG:

105517028(ITPK1)

CJC:	100396941(ITPK1)

SBQ:	101039869(ITPK1)

CIMI:

108316845(ITPK1)

ANAN:

105717783(ITPK1)

CSYR:

103275203(ITPK1)

MMUR:

105856742(ITPK1)

LCAT:

123645174(ITPK1)

PCOQ:

105819060

OGA:	100954286(ITPK1)

MMU:	217837(Itpk1)

MCAL:

110307175(Itpk1)

MPAH:

110324479(Itpk1)

RNO:	500709(Itpk1)

MCOC:

116079633(Itpk1)

ANU:	117697439(Itpk1)

ASYL:

127687011(Itpk1)

MUN:	110541472(Itpk1)

CGE:	100768438(Itpk1)

MAUA:

101823265(Itpk1)

PROB:

127231087(Itpk1)

PLEU:

114706069(Itpk1)

MORG:

121434439(Itpk1)

MFOT:

126507269

AAMP:

119819409(Itpk1)

NGI:	103724593(Itpk1)

HGL:	101700462(Itpk1)

CPOC:

100717610(Itpk1)

CCAN:

109693572(Itpk1)

DORD:

105986629(Itpk1)

DSP:	122118804(Itpk1)

PLOP:

125363658(Itpk1)

NCAR:

124977037

MMMA:

107144651(Itpk1)

ITI:	101967140(Itpk1)

OCU:

100345790

OPI:	101533405(ITPK1)

TUP:	102479480(ITPK1)

GVR:	103610819(ITPK1)

CFA:	490591(ITPK1)

CLUD:

112672682(ITPK1)

VVP:	112909607(ITPK1)

VLG:	121492932(ITPK1)

NPO:	129514990(ITPK1)

AML:	100484787(ITPK1)

UMR:	103673773(ITPK1)

UAH:	113267338(ITPK1)

UAR:	123798875(ITPK1)

ELK:

111148744

LLV:

125104278

MPUF:

101684430(ITPK1)

MNP:	132000211(ITPK1)

MLK:	131836928(ITPK1)

NVS:	122894464(ITPK1)

ORO:	101385854(ITPK1)

EJU:	114205219(ITPK1)

ZCA:	113909512(ITPK1)

MLX:	118002511(ITPK1)

NSU:	110571751(ITPK1)

FCA:	101087672(ITPK1)

PYU:	121032216(ITPK1)

PCOO:

112855983(ITPK1)

PBG:	122469466(ITPK1)

PVIV:

125167860(ITPK1)

LRUF:

124512560

LGF:	123582063(ITPK1)

AJU:

106980827

PTG:	102951160(ITPK1)

PPAD:

109274481(ITPK1)

PUC:

125909231

PLEZ:

122223075(ITPK1)

HHV:	120220241(ITPK1)

BTA:	518488(ITPK1)

BOM:	102279411(ITPK1)

BIU:	109575578(ITPK1)

BBUB:

102415988(ITPK1)

BBIS:

104985868(ITPK1)

CHX:	102183460(ITPK1)

OAS:	101115161(ITPK1)

BTAX:

128066442(ITPK1)

CSUM:

138095178(ITPK1)

ODA:	120874979(ITPK1)

CCAD:

122454855(ITPK1)

MREE:

136147217(ITPK1)

OVR:	110126340(ITPK1)

MBEZ:

129550596(ITPK1)

SSC:	100152339(ITPK1)

CFR:	102508931(ITPK1)

CBAI:

105079999(ITPK1)

CDK:	105095826(ITPK1)

VPC:	102531390(ITPK1)

BACU:

103011955(ITPK1)

BMUS:

118890554(ITPK1)

LVE:	103084508(ITPK1)

OOR:	101270326(ITPK1)

LALB:

132529912(ITPK1)

DLE:	111176142(ITPK1)

PCAD:

102992293(ITPK1)

PSIU:

116748928(ITPK1)

NASI:

112393868(ITPK1)

ECB:	100063828(ITPK1) 111770385

EPZ:	103556533(ITPK1)

EAI:	106825383(ITPK1)

MYB:	102246792(ITPK1)

MYD:	102764458(ITPK1)

MMYO:

118659788(ITPK1)

MLF:	102426532(ITPK1)

MDT:	132230304(ITPK1)

MYUM:

139009319 139010277

PKL:	118704212(ITPK1)

EFUS:

103302901(ITPK1)

MNA:	107531577(ITPK1)

DRO:	112311350(ITPK1)

SHON:

118976637(ITPK1)

AJM:	119037888(ITPK1)

PDIC:

114492322(ITPK1)

PHAS:

123808540(ITPK1)

MMF:	118631619(ITPK1)

PPAM:

129065815(ITPK1)

HAI:	109376793(ITPK1)

RFQ:	117023519(ITPK1)

PALE:

102877958(ITPK1)

PGIG:

120619630(ITPK1)

PVP:	105300812(ITPK1)

RAY:	107511245(ITPK1)

MJV:	108409820(ITPK1)

TOD:	119239449(ITPK1)

SARA:

101550768(ITPK1)

SFUM:

130041383(ITPK1)

SETR:

126003578(ITPK1)

LAV:	100668527(ITPK1)

TMU:

101341573

ETF:	101657568(ITPK1)

DNM:	105744380(ITPK1)

MDO:	100014342(ITPK1)

GAS:	123237854(ITPK1)

SHR:	100924957(ITPK1)

AFZ:

127549383

PCW:	110217744(ITPK1)

TVP:	118828218(ITPK1)

PBRV:

138159699(ITPK1)

OAA:	100079832(ITPK1)

TACU:

119930459(ITPK1)

GGA:	423421(ITPK1)

PCOC:

116228893(ITPK1)

MGP:	100541150(ITPK1)

CJO:	107315185(ITPK1)

TPAI:

128085550(ITPK1)

LMUT:

125695594(ITPK1)

NMEL:

110402115(ITPK1)

APLA:

101801656(ITPK1)

ACYG:

106033487(ITPK1)

CATA:

118244385(ITPK1)

AFUL:

116489779(ITPK1)

TGU:	100222999(ITPK1)

LSR:	110476414(ITPK1)

SCAN:

103826463(ITPK1)

PMOA:

120503728(ITPK1)

OTC:	121341610(ITPK1)

PRUF:

121355947(ITPK1)

ATRC:

139589820(ITPK1)

GFR:	102034047(ITPK1)

FAB:	101819235(ITPK1)

OMA:	130254201(ITPK1)

PHI:	102106037(ITPK1)

PMAJ:

107205493(ITPK1)

CCAE:

111929864(ITPK1)

CCW:	104688688(ITPK1)

CBRC:

103612217(ITPK1)

ACOE:

138111787(ITPK1)

ETL:	114060630(ITPK1)

ZAB:	102065748(ITPK1)

ZLE:	135448116(ITPK1)

ACHL:

103803575(ITPK1)

SVG:	106858038(ITPK1)

MMEA:

130576179(ITPK1)

HRT:	120753993(ITPK1)

SATI:

136362876(ITPK1)

CCIC:

134045651(ITPK1)

FPG:	101920131(ITPK1)

FCH:	102048369(ITPK1)

CCRI:

104158315(ITPK1)

NNT:	104413430(ITPK1)

SHAB:

115606892(ITPK1)

ACUN:

113480449(ITPK1)

TALA:

104357295(ITPK1)

ACHC:

115349380(ITPK1)

HALD:

104322798(ITPK1)

HLE:	104841876(ITPK1)

AGEN:

126050626

HHAR:

128139908(ITPK1)

GCL:

127017401

CSTI:

104563893(ITPK1)

LDI:	104345780(ITPK1)

MNB:	103775268(ITPK1)

DPUB:

104306341(ITPK1)

PPUS:

135174871(ITPK1)

AVIT:

104268513(ITPK1)

BRHI:

104502212(ITPK1)

EGZ:	104135355(ITPK1)

NNI:	104022228(ITPK1)

PCRI:

104031062(ITPK1)

PCAO:

104047984(ITPK1)

PADL:

103923943(ITPK1)

AFOR:

103900298(ITPK1)

FGA:	104072571(ITPK1)

GSTE:

104259981(ITPK1)

CLV:	102088692(ITPK1)

MUI:	104539256(ITPK1)

PGUU:

104466659(ITPK1)

PLET:

104625058(ITPK1)

EHS:	104506372(ITPK1)

CMAC:

104483181(ITPK1)

CUCA:

104057771(ITPK1)

TEO:	104377954(ITPK1)

BREG:

104638952(ITPK1)

OHA:	104331548(ITPK1)

ACAR:

104532972(ITPK1)

CPEA:

104394198(ITPK1)

CVF:	104295708(ITPK1)

RTD:	128908680(ITPK1)

CRID:

134514598(ITPK1)

AAM:	106483074(ITPK1)

AROW:

112972647(ITPK1)

NPD:	112953422(ITPK1)

TGT:	104565724(ITPK1)

DNE:	112990288(ITPK1)

SCAM:

104153805(ITPK1)

ASN:	102373418(ITPK1) 112548809

AMJ:	102575334(ITPK1) 109280689

CPOO:

109321703(ITPK1)

GGN:	109298509(ITPK1)

PSS:	102452019(ITPK1)

CMY:	102932685 102933310(ITPK1)

CCAY:

125628202 125638052(ITPK1)

DCC:	119847095 119857183(ITPK1)

CPIC:

101948262(ITPK1) 101949054

TST:	117876182(ITPK1) 117888741

CABI:

116822434 116827590(ITPK1)

MRV:	120388697 120403887(ITPK1)

ACS:	100566274(itpk1)

ASAO:

132763091(ITPK1)

PVT:	110083634(ITPK1)

SUND:

121919437(ITPK1)

PBI:	103054635(ITPK1)

PMUR:

107295460(ITPK1)

CTIG:

120318375(ITPK1)

TSR:	106549451(ITPK1)

PGUT:

117665930(ITPK1)

APRI:

131187867(ITPK1)

PTEX:

113444506(ITPK1)

VKO:	123026962(ITPK1)

PMUA:

114590768(ITPK1)

PRAF:

128407696(ITPK1)

ZVI:	118080978(ITPK1)

HCG:	128329708(ITPK1)

GJA:	107123858(ITPK1)

STOW:

125426663(ITPK1)

EMC:	129325307(ITPK1)

XLA:	108698651(XB5961849.L) 108700483(itpk1.S) 108700676(XB5961849.S) 379828(itpk1.L)

XTR:	100144987 549890(itpk1)

NPR:	108788675(ITPK1) 108804962

RTEM:

120913422 120921043(ITPK1)

BBUF:

120978272 120982050(ITPK1)

BGAR:

122922135(ITPK1) 122946405

PWL:	138259284 138260081(ITPK1)

MUO:	115477710(ITPK1) 115480378

GSH:	117364055(ITPK1) 117365641

DRE:	100148744(itpk1b) 406290(itpk1a)

SRX:	107711651 107721336 107731940(itpk1) 107755687

SANH:

107659161 107664466 107665329 107703450

SGH:	107561681 107586239 107586822 107602955

CCAR:

109044835 109081343 109081348 109108860(itpk1a)

CAUA:

113060546 113062907 113075671 113117113 113120916

CGIB:

127938901 127984441 128031687

PTET:

122325074(itpk1a) 122361739(itpk1b)

LROH:

127179950(itpk1b) 127182890(itpk1a)

OMC:	131522861(itpk1b) 131527522(itpk1a)

PPRM:

120475689(itpk1b) 120493467(itpk1a)

RKG:	130088336(itpk1b) 130091846(itpk1a)

MAMB:

125268972(itpk1b) 125277922(itpk1a)

CIDE:

127499000 127502053

CERY:

137006944(itpk1b) 137018983(itpk1a)

MASI:

127410297 127411334 127416482 127454873

TROS:

130560007(itpk1b) 130566111(itpk1a)

TDW:	130434709(itpk1a) 130436645(itpk1b)

MANU:

129417476(itpk1b) 129429540(itpk1a)

PDAB:

135737965 135738825(itpk1a) 135778126(itpk1b)

IPU:	108257830(itpk1a) 108270336(itpk1b) 108277840

IFU:	128601055(itpk1a) 128601157 128612408(itpk1b)

PHYP:

113538713(itpk1) 113544625 113547677

SMEO:

124377349(itpk1a) 124389844(itpk1b)

TFD:	113637823 113643345(itpk1a) 113659458(itpk1b)

TVC:	132843017(itpk1a) 132852602(itpk1b) 132858242

CGAR:

128515397(itpk1a) 128533482 128535916(itpk1b)

NGRA:

132883097(itpk1a) 132894421(itpk1b) 132900174

TRN:	134320126(itpk1a) 134325229(itpk1b)

AMEX:

103031945(itpk1b) 103039449(itpk1a)

CMAO:

118797196 118815664(itpk1a) 118824009(itpk1b)

EEE:	113570559 113583305

CHAR:

105897040(itpk1a) 105909690

SPIL:

134067331(itpk1b) 134097488(itpk1a) 134099432

TRU:	101069194(itpk1) 101072928

TFS:	130535290 130539684(itpk1b)

TNG:	GSTEN00026785G001 GSTEN00032247G001

LCO:	104927221 109142672(itpk1)

NCC:	104941855(itpk1) 104945354

TBEN:

117470023 117477794(itpk1b)

CGOB:

115017677 115017929 115027170(itpk1)

PGEO:

117467674(itpk1b)

GACU:

117550030(itpk1b)

EMAC:

134880236 134881291(itpk1b)

ELY:	117259817 117267012(itpk1b)

EFO:	125888865 125900464(itpk1b)

PLEP:

121942983 121953725(itpk1b)

SLUC:

116035499(itpk1b) 116038963

ECRA:

117936056(itpk1b) 117942589

ESP:	116670676(itpk1) 116681334

PFLV:

114547221(itpk1) 114553241

GAT:	120823661 120832914(itpk1b)

PPUG:

119216237 119227175(itpk1b)

AFB:	129091902 129103319(itpk1b)

CLUM:

117741987 117751166(itpk1b)

PSWI:

130202045(itpk1b) 130210982

CANA:

137787310(itpk1b) 137791132

CVE:	137869299 137884494

MSAM:

119883006 119910030(itpk1b)

SCHU:

122862295(itpk1b) 122878498

CUD:	121522245 121526496(itpk1b)

SPUL:

138591553(itpk1b) 138604598

LMIX:

132979817 132993291(itpk1b)

ALAT:

119004416(itpk1b) 119033877

ASTR:

137596604 137611387(itpk1b)

MZE:	101469029(itpk1) 101485309

ONL:	100691819 100698428(itpk1)

OAU:	116321627 116334744(itpk1b)

OLA:	101157334(itpk1)

OML:	112145038(itpk1b)

CSAI:

133462250(itpk1b)

XMA:	102220593(itpk1)

XCO:	114133945(itpk1)

XHE:	116708711(itpk1)

PRET:

103458928(itpk1)

PFOR:

103154786

PLAI:

106956954(itpk1)

PMEI:

106928494(itpk1)

GAF:	122845983(itpk1b)

PPRL:

129374749(itpk1b)

CVG:	107099127(itpk1)

CTUL:

119771439(itpk1b)

GMU:	124855132(itpk1b)

NFU:	107392041(itpk1)

KMR:	108237618(itpk1b)

ALIM:

106521176(itpk1)

NWH:	119427549(itpk1b)

AOCE:

111566021 111578952(itpk1b)

EJA:	138197047 138199913(itpk1b)

BFRE:

138618544 138630484(itpk1b)

MCEP:

125013256 125023572(itpk1b)

CSEM:

103377198(itpk1) 103378259

POV:	109634402 109647265

SSEN:

122773178 122782661(itpk1b)

SSOE:

131445155(itpk1b) 131462973

HHIP:

117755878(itpk1b) 117772629

HSP:	118106234 118116460(itpk1b)

PPLT:

128440380 128450587(itpk1b)

SMAU:

118285633(itpk1b) 118299411

LCF:	108883135 108891823 108892538(itpk1b)

SDU:	111225701(itpk1) 111232797

SLAL:

111654242 111659818(itpk1)

XGL:	120792565 120795007(itpk1b)

HCQ:	109510866 109516026(itpk1)

SSCV:

125971759 125980665(itpk1b)

SBIA:

133504913 133513218(itpk1b)

PEE:	133405397 133412469(itpk1b)

PTAO:

133481937 133487684(itpk1b)

BPEC:

110153603 110155270(itpk1)

ENY:	140370181(itpk1b) 140371725

MALB:

109955064(itpk1)

BSPL:

114848330(itpk1b)

SJO:	128359808 128375552(itpk1b)

SSCO:

133980538 134000550

GMH:	115543985(itpk1) 115561475

SASA:

106571690(itpk1) 106580902 106597151

STRU:

115162264 115162804 115172556 115174636

OTW:	112250446(itpk1a) 112256745(itpk1b) 112261728 112265274

OMY:	110497861 110505606(itpk1b) 110507571 110529743(itpk1a)

OGO:	123990876(itpk1a) 123992315 124002089 124046500

ONE:	115107882 115137805 115138552 115146182

OKI:	109894462 109900861 109904093 109906063

OKE:	118362552 118368256 118396942 118398525(itpk1a)

OMM:	135505838(itpk1a) 135508164 135525823 135552719

OCLA:

139375182 139383348 139385414 139415244

SALP:

111949749 111954658 111963320 111968685

SNH:	120018641 120023839 120024115(itpk1a) 120060329

CCLU:

121539329 121544863 121552857(itpk1a) 121563896

ELS:	105015588 105017670

OEP:	134024765(itpk1a) 134027160(itpk1b) 134029528

SFM:	108919611(itpk1)

PKI:	111838846(itpk1) 111854941

AANG:

118208907 118229489 118231456

AROT:

135237043 135249642 135257138

CCOG:

133108362 133129631 133133789

LOC:	102683027 102693298(itpk1)

PSPA:

121303893 121304850 121324402 121330127

ARUT:

117414905 117422543 117962632

PSEX:

120533699

LCM:	102351625(ITPK1) 102366649

CMK:	103185398(itpk1a)

RTP:

109929038

CPLA:

122542774 122553438(itpk1a)

HOC:	132818378(itpk1a) 132836601

LERI:

129699961(itpk1a) 129714116 129714118

PMRN:

116939790 116948276

LRJ:	133347297(ITPK1)

BFO:	118404175 118413213

BBEL:

109463636 109475020

CIN:

100181853

SCLV:

120335626

SPU:

580408

LPIC:

129265089

AJJ:

139972004

APLC:

110977634

ARUN:

117297963

AAMU:

139947555

AFIL:

140153650

SKO:

102806915

PFLL:

139150015

AME:

551726

ACER:

107994503

ALAB:

122710425

ADR:

102679234

AFLR:

100871017

BIM:

100740014

BBIF:

117209626

BVK:

117234605

BVAN:

117158611

BHUN:

126866653

BTER:

100647743

BAFF:

126926101

BPYO:

122572192

BPAS:

132909313

FVI:

122536487

CCAL:

108625595

OBB:

114880042

OLG:

117605807

MGEN:

117223447

NMEA:

116426113

CGIG:

122402622

SOC:

105195554

MPHA:

105840617

AEC:

105150186

ACEP:

105618310

PBAR:

105426206

VEM:

105569711

COBS:

139103859

TLN:

139819062

HST:

105181094

DQU:

106743443

CFO:

105250081

FEX:

115234407

PMEC:

138941056

LHU:

105673912

PGC:

109863770

OBO:

105280103

PCF:

106784291

PFUC:

122520621

VPS:

122638024

VCRB:

124428021

VVE:

124946757

NVI:

100117094

CSOL:

105361542

TPRE:

106658451

LHT:

122505432

LBD:

127278564

MDL:

103578390

CGLO:

123264471

FAS:

105270176

DAM:

107048650

AGIF:

122851371

VCAN:

122415869

CCIN:

107263896

DSM:

124413248

NPT:

124221823

NFB:

124185130

NLO:

107218311

NVG:

124307535

AROA:

105690793

TCA:

660348

TMOL:

138132789

DPA:

109544935

ESIM:

136408094

EFOR:

136342841

SOY:

115886107

AGRG:

126737456

ATD:

109595277

CSET:

123314815

HAXR:

123674475

AGB:

108906123

LDC:

111504364

DVV:

114327223

NVL:

108567762

APLN:

108733110

PPYR:

116168817

OTU:

111415796

BMOR:

101744563

MSEX:

115442955

DPL:	KGM_207895

BANY:

112048167

MJU:

123872983

NIQ:

126769348

VCD:

124535566

MCIX:

123661248

PMAC:

106719950

PPOT:

106101603

PXU:

106121615

BPHI:

137929709

PRAP:

110991381

PBX:

123717600

PNAP:

125051573

ZCE:

119832883

CCRC:

123697388

LSIN:

126968074

AAGE:

121734911

HAW:

110378751

HZE:

124636139

TNL:

113495593

SLIU:

111356499

OFU:

114360747

ONU:

135078234

ATRA:

106135711

GMW:

113512807

PXY:

105397344

PGW:

126373014

LGLY:

125235376

CSTB:

134747993

CCRN:

123292727

API:

100159102

DNX:

107163234

AGS:

114125796

RMD:

113548798

ACOO:

126834395

DVT:

126905520

BTAB:

109030649

CLEC:

106662859

HHAL:

106683832

NLU:

111054941

HVI:

124358128

MQU:

128985599

PHU:	Phum_PHUM230610

FOC:

113218210

TPAL:

117641348

ZNE:

110837839

CSEC:

111872081 111874476

SGRE:

126292161

BROR:

134527894

IEL:

124153576

HAMR:

139688265

FCD:

110844108

DPX:	DAPPUDRAFT_301724

DMK:

116930195

DPZ:

124340425

PVM:

113809605

PJA:

122243253

PCHN:

125039986

PMOO:

119575539

HAME:

121861033

PCLA:

123775189

CQD:

128694259

PTRU:

123514722

ESN:

126995738

MNZ:

135219102

MRJ:

136855906

PORN:

139760326

HAZT:

108677926

DSV:

119435525

RSAN:

119401323

RMP:

119163988

VDE:

111243985

VJA:

111262704

TUT:	107370058 107371154

DPTE:

113793158

DFR:

124492815

CSCU:

111635823

CVS:

136969584

PTEP:

107453142

ABRU:

129975216

UDV:

129232816

SDM:

118187866

PMEO:

129583283

HRO:	HELRODRAFT_194518

LGI:	LOTGIDRAFT_127367

PVUL:

126822044

PCAN:

112570001

LSAX:

138951655

BGT:

106055341

GAE:

121371138

HRF:

124140664

HRJ:

124279382

HASI:

137293693

HCRA:

139444403

CRG:

105337850

CANU:

128176713

CVN:

111130239

OED:

125650656

MYI:

110440574

PMAX:

117323184

AIRR:

138318595

MCAF:

127732730

MMER:

123531371

RPHI:

132719706

DPOL:

127873332 127880886

MAEA:

128209586

OBI:

106874910

OSN:

115209398

LJP:

135469156

LAK:	106160604 106170393 106171083

SMM:	Smp_098320

SHX:	MS3_00007331(ITPK1_1)

OVI:	T265_09366 T265_09369

LLON:

135484096 135484099

NVE:

5508018

EPA:

110247170

ATEN:

116308392

AMIL:

114966681

MCAZ:

138026058

MFOO:

137979447

PDAM:

113668546

SPIS:

111319149

DGT:	114520227 114536682

XEN:

124441063

HMG:	100204780 100211606 100215092

HSY:	130648535 130648903 130649034

RES:	135691611 135695336

TAD:	TRIADDRAFT_57121

ATH:	AT4G08170 AT4G33770 AT5G16760(ITPK1)

ALY:	9303232 9309859 9310588 9319911

CRB:	17877434 17882423 17884037

CSAT:

104705970 104716774 104721437 104722146 104729872 104735712 104736861 104769964 104772301 104773596

EUS:	EUTSA_v10014130mg EUTSA_v10022771mg EUTSA_v10025442mg

BRP:	103834460 103844358 103846299 103849070 103856211 103860402 103862265

BNA:	106359776 106361132 106371954 106387691 106404797 106412019 106432792 106438554 106439740 106441157 111204326 125590168

BOE:	106307058 106313146 106324602 106329077 106331834 106333305

RSZ:	108814325 108819938 108830306 108843921 108848887 108851395 108857551 130503074 130508363

THJ:	104799839 104807207 104820897 104825803 104827199

CPAP:

110806975 110807834 110810477

CIT:	102618028 102618843 102621784 102623644 102629950

CIC:	CICLE_v10001756mg CICLE_v10021128mg CICLE_v10024487mg CICLE_v10024568mg CICLE_v100287892m

PVY:	116106681 116108141 116129209 116130645 116132374

MINC:

123195519 123203013 123204658 123223424 123227635 123230085

TCC:	18591899 18599545 18606781 18608125

GRA:	105769390 105774216 105787950 105795156 105800315 105802002

GHI:	107886971 107890607 107905183 107907287 107912173 107923679 107930531 107935207 107950542 107957873 121210601 121214831

GAB:	108453113 108454385 108454783 108463237 108463901 108466720 108475927

HSYR:

120118518 120133556 120135032 120171635 120175033 120191666 120194521 120206724 120207094 120209854 120213557 120214929 120216587

DZI:	111276121 111276908 111280806 111281794 111290312 111304668 111309035 111312513

EGR:	104419801 104442035 104443532

RARG:

115735990 115737008 115739595 115743199

GMX:	100127408(ITPK2) 100127409(ITPK3) 100127410(ITPK4) 100127430(ITPK1) 100776901 100779381 100794373

GSJ:	114369542 114390544 114393824 114403913 114409155 114415191

PVU:	137807873 137808669 137821494 137828424

VRA:	106753331 106762117 106770808 106777318 106780148

VAR:	108324293 108331691 108331730 108335333 108344323

VUN:	114163097 114174259 114175756 114178345 114189841

VUM:	124822562 124823644 124823646 124831388 124831389 124840592 124841986

CCAJ:

109791328 109796596 109810819 109812231 109817019

APRC:

113845979 113851222 113864527 113869558 113872970

MTR:	11428245 11437604 25485299 25493763

TPRA:

123882190 123885814 123907855 123921112

CAM:	101496144 101510649 101515004

PSAT:

127073923 127075024 127076845 127094570

VVO:	131601992 131620572 131622364 131636389 131643408 131652627

LJA:	130711210 130711609 130718603 130727655 130740155

ADU:	107461048 107471301 107487187 107488659 107491809

AIP:	107606263 107624436 107632154 107642335 107643287

AHF:	112695385 112706310 112716303 112722341 112747418 112764714 112784965 112800031 112801209

LANG:

109327002 109327608 109328570 109330496 109332643 109336804 109350257 109362481

PCIN:

129293646 129302257 129310617 129320166 129321622

QSA:	O6P43_011850 O6P43_015457 O6P43_022709 O6P43_025140 O6P43_030865 O6P43_031156 O6P43_033338

FVE:	101292561 101308465 101309301 101312158

AANS:

126782929 126793389 126796177 126802492

RCN:	112172788 112172949 112177047 112179721

PPER:

18767691 18777458 18785753 18792697

PMUM:

103319395 103333485 103335030 103336869

PAVI:

110758620 110760197 110772105 110772420

PDUL:

117614794 117619036 117628820 117638703

MDM:	103403679 103420816 103428854 103436308 103436916 103441763 103444921 103445688 114825442

MSYL:

126587348 126608475 126621731 126625087 126625862 126626055 126628600 126632405

PXB:	103928083 103928193 103932352 103938119 103943282 103951494 103960446

PCOX:

137711139 137717748 137720401 137724902 137727977 137729450 137731322 137733915

ZJU:	107408660 107414875 107426149 107435278

MNT:	21386897 21400765 21402601 21408206

CSAV:

115695287 115716459 133031693 133038085

CSV:	101206636 101211366 101211396 101218009 101223134

CMO:	103488158 103490768 103498372 103498455 103503561

BHJ:	120076365 120078525 120087753 120087879 120091042

MCHA:

111004509 111004909 111014868 111017207

CMAX:

111466852 111484264 111484270 111492079 111496260 111498432 111499970 111499976 111500155

CMOS:

111431034 111431242 111448363 111448365 111451086 111451089 111454526 111462935 111463848

CPEP:

111776732 111777536 111785867 111794755 111795408 111795517 111799094 111800839 111805405 111809705 111811338

RCU:	8268910 8280498 8288086

MEAN:

126659716 126673906 126683977

JCU:	105630780 105632459

HBR:	110635067 110643582 110647189 110649301 110661899 110673132 110673515

MESC:

110606551 110615946 110619522 110620064

POP:	18094146 18108288 7469654 7489780 7491867

PEU:	105109413 105117948 105121550 105128262 105138604

PALZ:

118028349 118030151 118039247 118042934 118046489 118059069

PNZ:	133667915 133680294 133689723 133694600 133700820

JRE:	108992108 108992384 109004669 109012407 109015498 109022215

CILL:

122281535 122289069 122296007 122310519 122311356 122312842

CAVE:

132162712 132174855 132177702 132185031

AGLU:

133854196 133855232 133865765 133881998

QSU:	112004346 112006601 112006602 112006606 112006621 112006623 112015849 112034521 136065940 136070362

QLO:	115960390 115960446 115962243 115968657 115970051 115972397

TWL:	119981492 119982153 119992430 120010882 120016083

VVI:	100242009 100267838 100853468

VRI:	117906938 117907385 117933904 117934087

SLY:	101246342 101248031 101253265 101262094 101262540 101262819 101265624

SPEN:

107005342 107013010 107013860 107015624 107021629 107026836 107027164

SOT:	102577926(IPKA) 102584612 102585707 102593136 102598871 107060680

SSTN:

125842526 125857036 125858470 125859747 125861713 125875131 125878383

SDUL:

129880588 129888772 129895014 129898907 129902600

CANN:

107850486 107850725 107862895 107862921 107867306 107870752 107875799

LBB:	132602721 132604045 132609720 132627702 132632286 132635314

NTA:	107764060 107770443 107778733 107785683 107799749 107804003 107813251 107813668 107814144 107815734 107830477 107832605

NSY:	104214334 104218768 104230155 104235587 104238992 104249518

NTO:	104091977 104106303 104108064 104114013 104117581 104119291

NAU:	109213048 109215967 109219793 109220392 109239463 109242156

INI:	109146505 109153336 109153361 109170040

ITR:	115999090 116022537 116026626 116027417

SIND:

105159068 105160205 105165150 105169348 105179082

OEU:	111380716 111383350 111386493 111393693 111396007 111396097

EGT:	105957462 105959294 105961618 105964646

SSPL:

121753902 121755376 121756259 121756342 121756925 121758710 121758885 121760261 121761943 121763585 121763625 121788447 121792786 121793016 121803245 121809138

SMIL:

131005238 131010636 131014980 131016107

SHIS:

125191935 125201502 125219319 125220775 125222228 125222238

APAN:

127240140 127246785 127248343 127252352 127252365 127259724 127264934

HAN:	110864567 110899432 110906326 110916325 110919889 110920107 110930253

ECAD:

122582408 122597270 122597272 122600009 122607473

LSV:	111884189 111894708 111898297 111898382 111918111

CCAV:

112503467 112510271 112511098 112523965 112527910

DCR:	108205361 108209750 108211360 108213312 108215400 108215892

CSIN:

114279310 114281532 114299547 114310839 114313576

RVL:	131307817 131329216 131333700

AEW:	130755694 130757836 130764447 130765655 130767048 130775509 130776145 130793239

DLT:	127787398 127806204 127808105

BVG:	104887991 104887992 104897568 104904836 104905734 104908161

SOE:	110786125 110791914 110794403 110797685 110804679

CQI:	110685009 110688755 110693036 110712456 110717936 110719966 110730160 110732563 110740001

ATRI:

130798097 130801596 130806398 130810515 130821779 130826623

MOF:	131161280 131164137

NNU:	104585640 104589111 104604214 104609603

MING:

122070684 122084598 122085004 122089168

TSS:	122644612 122658421 122662295 122665373

PSOM:

113285399 113288463 113299909 113299910 113322293 113331938 113347377 113362196

OSA:	4329322(ITPK4) 4332146(DSM3) 4333967(OsITPK3) 4347947(ITPK1) 4349492(ITPK5)

DOSA:

Os02g0466400 Os03g0230500 Os03g0726200 Os10g0103800 Os10g0576100

OBR:	102699763 102705982 102706787 102709030 102711679

OGL:	127753115 127762532 127767562 127767635 127786004

BDI:	100821944 100824610 100824952 100839314

ATS:	109732807 109748791 109751093 109759444

TDC:	119273184 119285016 119286627 119286815 119291113 119294902 119333438 119337486 119338367 119348963

TAES:

123050359 123062556 123085097 123087024 123090936 123092886 123095966 123098166 123125975 123139798 123154092 123159722 123166273 123181474 123182602

TUA:	125523690 125524495 125550490 125552439

LPER:

127293068 127294426 127296312 127298034 127312697 127317861

LRD:	124646490 124649855 124656745 124657926 124661822 124670877 124671152 124701848 124704107

SBI:	8055098 8055136 8056852 8059973 8084482

ZMA:	100194132 100282774 100282992 103627151 732818

MFLO:

136473570 136473595 136519295 136526890 136527450 136535306 136539060

SITA:

101760267 101767712 101772461 101775806 101776470 101777153 101781965

SVS:	117835850 117838000 117839800 117840449 117849286 117862938

PVIR:

120649911 120651552 120687250 120687869 120688517 120689016 120692366 120701183

PHAI:

112873481 112874997 112875034 112875785 112895088

PAUA:

133903031 133903379 133907550 133907641 133911962 133913206 133915540 133918914

PDA:	103704259 103704715 103705347 103707628 103711755

EGU:	105034864 105052534 105053838 105055908 105058175 105060139

MUS:	103978347 135582304 135605750 135607009 135607011 135608274 135610169

ZOF:	121981121 121985004 121989840 121992923 121996918 121998798 122009910 122012030 122016122 122017982 122019348 122023113 122026076 122030617 122039748 122043742 122043751 122048337 122048340 122048341 122048346 122049186 122051477 122056012

DCT:	110104742 110105426 110113941

PEQ:	110020760 110024926 110031979

AOF:	109822557 109825073 109834328

MSIN:

131218801 131228945 131232581 131248011

ACAK:

137934561 137948345 137952865

NCOL:

116246407 116249646 116250722 116252853 116255645 116266486

ATR:	18442479 18443476 18443787

CJF:	131073646 131073649 131077627 131078954

SMO:	SELMODRAFT_228325 SELMODRAFT_232261

PPP:	112272933 112274637 112289031 112290042 112296035

CRE:	CHLRE_01g018400v5

VCN:	VOLCADRAFT_97715

CSL:	COCSUDRAFT_64519

CVR:	CHLNCDRAFT_143754

APRO:

F751_4717

MIS:	MICPUN_84098

GSL:	Gasu_02310

CCP:	CHC_T00001462001

MBR:	MONBRDRAFT_33295

SRE:	PTSG_01647

DDI:	DDB_G0269746(ITPK1)

DPP:	DICPUDRAFT_146695

DFA:	DFA_02662(ITPK1)

EHI:	EHI_042120(11.t00022) EHI_100310(151.t00008)

EDI:	EDI_127070 EDI_256970

EIV:	EIN_046820

ACAN:

ACA1_117040

TET:	TTHERM_00530360

PTM:	GSPATT00028192001 GSPATT00034987001

PTI:	PHATRDRAFT_39499

FCY:	FRACYDRAFT_167635

TPS:	THAPSDRAFT_261937

PIF:	PITG_12275

PSOJ:

PHYSODRAFT_486429

TVA:	TVAG_2v1048890

GTT:	GUITHDRAFT_111570

» show all

Reference

1 [PMID:2829850]

Authors

Stephens LR, Hawkins PT, Morris AJ, Downes PC.

Title

L-myo-inositol 1,4,5,6-tetrakisphosphate (3-hydroxy)kinase.

Journal

Biochem J 249:283-92 (1988)
DOI:10.1042/bj2490283

Reference

2 [PMID:3497156]

Authors

Balla T, Guillemette G, Baukal AJ, Catt KJ.

Title

Metabolism of inositol 1,3,4-trisphosphate to a new tetrakisphosphate isomer in angiotensin-stimulated adrenal glomerulosa cells.

Journal

J Biol Chem 262:9952-5 (1987)

Reference

3 [PMID:2823793]

Authors

Shears SB, Parry JB, Tang EK, Irvine RF, Michell RH, Kirk CJ.

Title

Metabolism of D-myo-inositol 1,3,4,5-tetrakisphosphate by rat liver, including the synthesis of a novel isomer of myo-inositol tetrakisphosphate.

Journal

Biochem J 246:139-47 (1987)
DOI:10.1042/bj2460139

Reference

4 [PMID:2584198]

Authors

Shears SB.

Title

The pathway of myo-inositol 1,3,4-trisphosphate phosphorylation in liver. Identification of myo-inositol 1,3,4-trisphosphate 6-kinase, myo-inositol 1,3,4-trisphosphate 5-kinase, and myo-inositol 1,3,4,6-tetrakisphosphate 5-kinase.

Journal

J Biol Chem 264:19879-86 (1989)

Reference

5 [PMID:11042108]

Authors

Yang X, Shears SB.

Title

Multitasking in signal transduction by a promiscuous human Ins(3,4,5,6)P(4) 1-kinase/Ins(1,3,4)P(3) 5/6-kinase.

Journal

Biochem J 351 Pt 3:551-5 (2000)

Sequence

[hsa:3705]

Reference

6 [PMID:11909533]

Authors

Ho MW, Yang X, Carew MA, Zhang T, Hua L, Kwon YU, Chung SK, Adelt S, Vogel G, Riley AM, Potter BV, Shears SB.

Title

Regulation of Ins(3,4,5,6)P(4) signaling by a reversible kinase/phosphatase.

Journal

Curr Biol 12:477-82 (2002)
DOI:10.1016/S0960-9822(02)00713-3

Sequence

[hsa:3705]

Other DBs

ExplorEnz - The Enzyme Database:

2.7.1.134

IUBMB Enzyme Nomenclature:

2.7.1.134

ExPASy - ENZYME nomenclature database:

2.7.1.134

BRENDA, the Enzyme Database:

2.7.1.134

CAS:	187175-98-0

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DBGET integrated database retrieval system