KEGG   ENZYME: 2.7.1.138
Entry
EC 2.7.1.138                Enzyme                                 
Name
ceramide kinase;
acylsphingosine kinase
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
Sysname
ATP:ceramide 1-phosphotransferase
Reaction(IUBMB)
ATP + ceramide = ADP + ceramide 1-phosphate [RN:R01495]
Reaction(KEGG)
R01495
Substrate
ATP [CPD:C00002];
ceramide [CPD:C00195]
Product
ADP [CPD:C00008];
ceramide 1-phosphate [CPD:C02960]
History
EC 2.7.1.138 created 1992
Pathway
ec00600  Sphingolipid metabolism
ec01100  Metabolic pathways
Orthology
K04715  ceramide kinase
Genes
HSA64781(CERK)
PTR458921(CERK)
PPS100993780(CERK)
GGO101151827(CERK)
PON100458044(CERK)
NLE100604178(CERK)
MCC714480(CERK)
MCF102127587(CERK)
CSAB103223647(CERK)
CATY105586910(CERK)
PANU101017998(CERK)
TGE112633301(CERK)
RRO104675624(CERK)
RBB108514496(CERK)
TFN117096301(CERK)
PTEH111548894(CERK)
CJC100389728(CERK)
SBQ101034547(CERK)
CSYR103257452(CERK)
MMUR105867150(CERK)
OGA100942132(CERK)
MMU223753(Cerk)
MCAL110310695(Cerk)
MPAH110334693(Cerk)
RNO300129(Cerk)
MCOC116077541(Cerk)
MUN110562370(Cerk)
CGE100763715(Cerk)
PLEU114699210(Cerk)
NGI103732300(Cerk)
HGL101720871(Cerk)
CPOC100724424(Cerk)
CCAN109696288(Cerk)
DORD105992712(Cerk)
DSP122123592(Cerk)
NCAR124982988
OCU100359094(CERK)
OPI101530946(CERK)
TUP102495155(CERK)
CFA474464(CERK)
VVP112935858(CERK)
VLG121490912(CERK)
AML100475487(CERK)
UMR103674127(CERK)
UAH113241567(CERK)
UAR123780540(CERK)
ELK111157462
LLV125107403
MPUF101680864(CERK)
ORO101364658(CERK)
EJU114218485(CERK)
ZCA113921874(CERK)
MLX117998465(CERK)
FCA101098065(CERK)
PBG122473695(CERK)
PTG102956613(CERK)
PPAD109265253(CERK)
AJU106967322(CERK)
HHV120234045(CERK)
BTA100336737(CERK)
BOM102267143(CERK)
BBUB102395822(CERK)
CHX102180489(CERK)
OAS101111625(CERK)
ODA120858461(CERK)
CCAD122423865(CERK)
SSC110260834(CERK)
CFR102520729(CERK)
CBAI105073176(CERK)
CDK105091835(CERK)
VPC102534863(CERK)
BACU103006157(CERK)
LVE103084594(CERK)
OOR101279664(CERK)
DLE111186394(CERK)
PCAD102984572(CERK)
PSIU116760045(CERK)
ECB100053604(CERK)
EPZ103541838(CERK)
EAI106845987(CERK)
MYB102255282(CERK)
MYD102752321(CERK)
MMYO118650384(CERK)
MLF102420658(CERK)
MNA107539750(CERK)
PKL118708767(CERK)
HAI109387642(CERK)
DRO112322045
SHON118989260(CERK)
AJM119060378(CERK)
PDIC114513958(CERK)
PHAS123816034(CERK)
MMF118641161(CERK)
RFQ117028287(CERK)
PALE102891072(CERK)
PGIG120602785(CERK)
PVP105305890(CERK)
RAY107500977(CERK)
MJV108406723(CERK)
TOD119248168(CERK)
SARA101540302(CERK)
LAV100656915(CERK)
TMU101344308
DNM101413619(CERK)
MDO100023501(CERK)
GAS123250273(CERK)
SHR100918913(CERK)
PCW110201623(CERK)
OAA100073563 100074743(CERK)
GGA425523(CERK)
PCOC116235019(CERK)
MGP100551089(CERK)
CJO107308211(CERK)
NMEL110392417(CERK)
APLA101803203(CERK)
ACYG106042026(CERK)
AFUL116485519(CERK)
TGU100225105(CERK)
LSR110467618(CERK)
SCAN103813710(CERK)
PMOA120510702(CERK)
OTC121336336(CERK)
PRUF121357398(CERK)
GFR102033498(CERK)
FAB101821837(CERK)
PHI102107221(CERK)
PMAJ107204847(CERK)
CCAE111923029(CERK)
CCW104686910(CERK)
ETL114061556(CERK)
ZAB102062163(CERK)
FPG101911886(CERK)
FCH102052067(CERK)
CLV102087252(CERK)
EGZ104123804(CERK)
NNI104010786(CERK)
ACUN113490126(CERK)
TALA104367482(CERK)
PADL103917278(CERK)
ACHC115341323(CERK)
AAM106487726(CERK)
AROW112960899(CERK)
NPD112953323(CERK)
DNE112980478(CERK)
ASN102374674(CERK)
AMJ102562077(CERK)
CPOO109315690(CERK)
GGN109292068(CERK)
PSS102445981 102462104(CERK)
CMY102936368(CERK) 102938596
CPIC101931362(CERK) 101942222
TST117875752(CERK)
CABI116817772(CERK) 116823439
MRV120388749 120391562(CERK)
ACS100555340(cerk) 100566923
PVT110080794(CERK) 110089201
SUND121922697 121931289(CERK)
PBI103052975 103055107(CERK)
PMUR107284208 107294274(CERK)
TSR106550042(CERK)
PGUT117675544 117679826(CERK)
VKO123020054(CERK) 123029962
PMUA114587308 114605271(CERK)
ZVI118091211(CERK) 118097668
GJA107112367(CERK) 107117363
STOW125434865(CERK)
XLA108699970 108704494(XB5892679.L) 444466(cerk.S) 444656(cerk.L)
XTR100487080(cerk) 779592
NPR108784942(CERK) 108791351
RTEM120914227 120931805(CERK)
BBUF120982228(CERK) 121009143
BGAR122919833 122927903(CERK) 122946661
DRE558496(cerk) 791197(zgc:158263)
SRX107710741 107716164 107721152
SANH107666216(cerk) 107668552 107689729 107695826
SGH107552286 107568456 107571455 107600034
CCAR109055268 109064309 109094430 109094552
CAUA113048069 113057940 113070521
PPRM120463823(zgc:158263) 120477109(cerk)
MAMB125244753(cerk) 125260444(zgc:158263)
IPU108276042(zgc:158263) 108279906(cerk)
PHYP113530631 113532018(cerk)
SMEO124398952(zgc:158263) 124401244(cerk)
TFD113641672(zgc:158263) 113645697(cerk)
AMEX103022908(cerk) 103040162
EEE113578603 113580191(cerk)
TRU101066930 101071768 101075523 115248180
TNGGSTEN00016056G001 GSTEN00019833G001 GSTEN00028121G001
LCO104926583 104932850 104932994
NCC104959447(cerk) 104967525
CGOB115009206 115009207 115010628 115028383(cerk)
ELY117248966(cerk) 117258524(zgc:158263) 117262176
PLEP121947473(zgc:158263) 121950743 121961605(cerk)
SLUC116036266 116039320(zgc:158263) 116039803(cerk)
ECRA117938862(cerk) 117947767(zgc:158263) 117949035
PFLV114550529 114559180 114560396
GAT120809239 120817989(cerk) 120829095(zgc:158263)
PPUG119196299(cerk) 119223331(zgc:158263)
MSAM119893588 119905501(zgc:158263) 119918286(cerk)
CUD121514786(cerk) 121517414(zgc:158263)
MZE101473714 101474144 101484257
ONL100699400 100702731 100704071
OAU116317483 116325814(zgc:158263) 116334953(cerk)
OLA101165056 101167008(cerk)
OML112153088(cerk) 112159029(zgc:158263)
XMA102228448(cerk) 102235563 102236610
XCO114146928 114158812 114160854
XHE116707888 116726892 116736583(cerk)
PRET103459525(cerk) 103465659 103467319
PFOR103141165 103149365 103155970(cerk)
PLAI106935741 106940780 106957636(cerk)
PMEI106903964 106914963 106927311(cerk)
GAF122826686(cerk) 122835192 122837611(zgc:158263)
CVG107086790 107093605 107099102(cerk)
CTUL119776266(cerk) 119780459 119782179(zgc:158263)
GMU124869770(zgc:158263) 124882735(cerk) 124884266
NFU107383858 107390850 107396077(cerk)
KMR108244042(cerk) 108244565(zgc:158263) 108249879
ALIM106524848 106525207 106530944(cerk)
NWH119415885 119417280(zgc:158263) 119428384(cerk)
AOCE111566194 111576527 111578634
CSEM103382938(cerk) 103384587
POV109624489 109630663 109632871(cerk)
SSEN122766532(cerk) 122776107 122777365(zgc:158263)
HHIP117757259(cerk) 117763413 117764771(zgc:158263)
LCF108876500 108893773 108899840
SDU111219249 111225074(cerk) 111235976
SLAL111665078 111667351 111670741
XGL120793660 120796821(cerk) 120804500(zgc:158263)
HCQ109520134 109522963 109528422
BPEC110161655 110164636 110169654
MALB109956432 109960999(cerk) 109969808
SASA106561037 106567014 106572704 106575992 106584603(cerk)
OTW112216776(cerk) 112218226 112218443 112221670(zgc:158263) 112232718
OMY110490163(cerk) 110491938(zgc:158263) 110492691 110521313 110532722
OGO123994729(cerk) 124032306 124037582 124039099 124046117(zgc:158263)
ONE115102676 115106863 115132514 115134476 115144772
SALP111951545 111962164 111966823 111971914 111976222
SNH120032228 120052373 120059591 120060961 120066130
ELS105006385 105013519 105020192(cerk)
SFM108920752 108931338 108939079
PKI111853395(cerk) 111857069
AANG118207826(zgc:158263) 118219031 118231865
LOC102683222 102691686(cerk)
PSPA121318341 121319754 121329110(zgc:158263)
ARUT117401623 117404159 117414678(cerk) 117419933 117968746 117968921
LCM102359903 102367605(CERK)
CMK103177038(cerk) 103179174
RTP109911504(cerk)
BFO118415986
BBEL109465520
CIN100178612
SCLV120326007
SPU115919524 593404
APLC110990169
SKO100378628
DMEDmel_CG16708(Cerk)
DER6552394
DSE6613931
DSIDsimw501_GD19624(Dsim_GD19624)
DYADyak_GE25291
DAN6500501
DSR110177104
DPODpse_GA14094
DPE6591764
DMN108157079
DWI6651003
DGR6567751
DMODmoj_GI10206
DAZ108608627
DNV108660212
DHE111604930
DVI6632896
CCAT101455427
BOD106619025
MDE101894449
SCAC106085818
LCQ111677899
AGAAgaP_AGAP002932
ACOZ120949238
AARA120908369
AAG5579301
AALB109405947 109406925
CQUCpipJ_CPIJ003342
CPII120425467
CNS116350882
AME408315
ACER107995902
ALAB122717987
BIM100746104
BBIF117211330
BVK117237354
BVAN117160900
BTER100645684
BPYO122572404
CCAL108629349
OBB114880721
MGEN117225261
NMEA116433615
CGIG122397477
SOC105207520
MPHA105829938
AEC105151775
ACEP105623648
PBAR105426473
VEM105567492
HST105183577
DQU106746607
CFO105254556
FEX115245407
LHU105676815
PGC109856454
OBO105288249
PCF106789375
PFUC122518535
VPS122631917
NVI100115381
CSOL105367759
TPRE106660413
MDL103577437
CGLO123263075
FAS105264209
DAM107042240
AGIF122854612
CCIN107273382
TCA657676
DPA109540932
SOY115887151
ATD109599334
CSET123321341
AGB108910988
LDC111514662
NVL108558915
APLN108733777
PPYR116165725 116180295
OTU111425382
BTAB109034768
NLU111049376 120354595
PHUPhum_PHUM614990
FOC113217498
ZNE110833010
CSEC111870120
FCD110850691
PJA122261105
PCHN125039087
HAME121860585
PCLA123759644
PTRU123499597
HAZT108665614
LSM121117520
ISCIscW_ISCW009373
DSV119461266
RSAN119396286
RMP119174519
VDE111246278
VJA111272010
TUT107363999
DPTE113789820
DFR124499794
CSCU111618012
PTEP107444911
SDM118205179
CELCELE_T10B11.2(cerk-1)
CBRCBG_12724
BMYBM_BM5707(Bma-cerk-1)
LOALOAG_11245
NAINECAME_14257
LGILOTGIDRAFT_161209 LOTGIDRAFT_168829
PCAN112572538 112573424 112573727
BGT106054994 106058521 106060093
GAE121367290 121375678 121375705
HRF124112005 124112007 124116993 124118774 124127860 124135615 124146248 124146250
HRJ124254841 124254852 124255069 124269656 124269657 124269658 124272807 124272808 124277348 124277365
CRG105321802 105322453 105334232 105343295 105343296 105344779 109619194 117689200
MYI110443540 110443548 110443726 110443789 110443793 110452554 110457812
PMAX117318763 117325148 117325150 117331678 117337830 117338314
MMER123524703 123525124 123525744 123528840
OBI106879156 106884171
OSN115211130 115214233 115226571
LAK106178654
SMMSmp_130110
OVIT265_11452
NVE5516349 5520348
EPA110236735 110237461
ATEN116288028 116304891
ADF107351535 107351555
AMIL114959157 114965386
PDAM113684080 113687016
SPIS111338904 111342301
DGT114521793
XEN124439492
HMG101241227
AQU105314130
ATHAT5G51290(ACD5)
ALY9300181
CRB17875383
CSAT104725638 104725930 104761129
EUSEUTSA_v10012981mg
BRP103857191
BNA106345877 106387924
BOE106336521
RSZ108847128
THJ104808276
CPAP110820388
CIT102620773
CICCICLE_v10004561mg
PVY116139697 116140453
MINC123197764 123226461
TCC18605306
GRA105764875
GHI107933494 107955111
GAB108479319
DZI111290010 111290446
EGR104424318
GMX100816467 100818087
GSJ114409389 114417412
PVUPHAVU_005G009000g
VRA106762464
VAR108347829
VUN114184672
CCAJ109819074
APRC113846911
MTRMTR_3g008260
CAM101493210
LJALj3g3v3430170.1(Lj3g3v3430170.1) Lj3g3v3430170.2(Lj3g3v3430170.2)
ADU107471838
AIP107622214
AHF112716892 112783083
LANG109338293 109346008
FVE101302509
RCN112194739
PPER18785244
PMUM103333455
PAVI110764704
PDUL117620064
MDM103424248
PXB103952751
ZJU107404404 107414146
MNT21385742
CSV101222000
CMO103482566
BHJ120069444
MCHA111024188
CMAX111490676
CMOS111459291
CPEP111795976
RCU8289641
JCU105648640
HBR110669606
MESC110616788
POP18098404
PEU105128473
PALZ118050109
JRE109002484
QSU112017209
QLO115960087
TWL119986330
VVI100257819
VRI117933054 117933831
SLY101267524
SPEN107018695
SOT102583597
CANN107848076
NTA107791052 107817825
NSY104234828
NTO104096400
NAU109221169
INI109146463
ITR115999690
SIND105160643
EGT105977907
SSPL121782865
HAN110905020 110915812
ECAD122588664 122604957
LSV111889935
CCAV112509879 112518699
DCR108193416 108219473
CSIN114314898
BVG104906643
SOE110782347
CQI110689306 110717570
NNU104598444 104610459
MING122084379
TSS122664365
PSOM113297183 113302500
NCOL116253086
OSA4330198
DOSAOs02t0656200-01(Os02g0656200)
OBR102707007
BDI100845296
ATS109740630
TDC119317324 119324293
TAES123127902 123137729 123144994
SBI8073961
ZMA100281194
SITA101782592
SVS117865227
PVIR120656685 120711509
PHAI112890352
PDA103711671
EGU105053969
MUS103970407
DCT110107797
PEQ110021917
AOF109839357
ATR18428228
SMOSELMODRAFT_443859 SELMODRAFT_93560
PPP112278893 112291468
CRECHLRE_09g393691v5
VCNVOLCADRAFT_118104(kdg4)
CSLCOCSUDRAFT_56197 COCSUDRAFT_66245
CVRCHLNCDRAFT_54812
APROF751_3214
MBRMONBRDRAFT_11991
SREPTSG_08413
GTTGUITHDRAFT_140864
 » show all
Reference
1  [PMID:2547795]
  Authors
Bajjalieh SM, Martin TF, Floor E.
  Title
Synaptic vesicle ceramide kinase. A calcium-stimulated lipid kinase that co-purifies with brain synaptic vesicles.
  Journal
J Biol Chem 264:14354-60 (1989)
Other DBs
ExplorEnz - The Enzyme Database: 2.7.1.138
IUBMB Enzyme Nomenclature: 2.7.1.138
ExPASy - ENZYME nomenclature database: 2.7.1.138
BRENDA, the Enzyme Database: 2.7.1.138
CAS: 123175-68-8
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