KEGG   ENZYME: 2.7.1.179
Entry
EC 2.7.1.179                Enzyme                                 
Name
kanosamine kinase;
rifN (gene name)
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
Sysname
ATP:kanosamine 6-phosphotransferase
Reaction(IUBMB)
ATP + kanosamine = ADP + kanosamine 6-phosphate [RN:R06588]
Reaction(KEGG)
R06588
Substrate
ATP [CPD:C00002];
kanosamine [CPD:C12212]
Product
ADP [CPD:C00008];
kanosamine 6-phosphate [CPD:C12213]
Comment
The enzyme from the bacterium Amycolatopsis mediterranei is specific for kanosamine.
History
EC 2.7.1.179 created 2013
Pathway
ec01051  Biosynthesis of ansamycins
ec01110  Biosynthesis of secondary metabolites
Orthology
K16018  kanosamine 6-kinase
Genes
SVLStrvi_5366
SMALSMALA_0448 SMALA_1353
SSOII1A49_05760 I1A49_10265
SRWTUE45_00083(rifN) TUE45_pSRc_0216(rifN)
SLEcxmN(cxmN)
SPAVSpa2297_32600
SAUOBV401_06000 BV401_10580
SVUB1H20_29915
SPUNBFF78_27090
SPHVF9278_17910
SSPBCP982_35340
SCYGS1361_01065(rifN1) S1361_34030(rifN2)
SCALI6J39_29720
SDDD9753_04160
YIALO772_07405
FRAFrancci3_0432
FREFranean1_1662
FALFRAAL0917
SENSACE_2869(rifN)
AMDAMED_0630(rifN)
AMNRAM_03220
AMMAMES_0628(rifN)
AMZB737_0629(rifN)
AABA4R43_38520
AMYYYIM_39455(rifN)
AORISD37_11005
PSEEFRP1_29595
PECQAD017_32800
APRECNX65_16255
AMIAmir_3285
ACTAC1701_25890
SAQSare_1275
MAUMicau_2445
MILML5_5917
MICBMicB006_3071
MCABHXZ27_10290
MSAGGCM10017556_49820(rifN)
ACTNL083_2901 L083_5701
PLABC6361_34550
PLATC6W10_21650
PRYPrubr_62850(rifN)
 » show all
Reference
1  [PMID:12207505]
  Authors
Arakawa K, Muller R, Mahmud T, Yu TW, Floss HG
  Title
Characterization of the early stage aminoshikimate pathway in the formation of 3-amino-5-hydroxybenzoic acid: the RifN protein specifically converts kanosamine into kanosamine 6-phosphate.
  Journal
J Am Chem Soc 124:10644-5 (2002)
DOI:10.1021/ja0206339
  Sequence
[amn:RAM_03220]
Other DBs
ExplorEnz - The Enzyme Database: 2.7.1.179
IUBMB Enzyme Nomenclature: 2.7.1.179
ExPASy - ENZYME nomenclature database: 2.7.1.179
BRENDA, the Enzyme Database: 2.7.1.179
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