| Entry |
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| Name |
D-erythrulose 4-kinase;
derK (gene name)
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| Class |
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with an alcohol group as acceptor
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| Sysname |
ATP:D-erythrulose 4-phosphotransferase
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| Reaction(IUBMB) |
ATP + D-erythrulose = ADP + D-erythrulose 4-phosphate [RN: R11461]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
The enzyme, characterized from the bacterium Mycobacterium smegmatis, participates in the degradation of erythritol and D-threitol.
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| History |
EC 2.7.1.210 created 2016
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| Orthology |
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| Genes |
| RTG: | NCTC13098_01632(dhaK_3) |
| HAAH: | HALA3H3_700020(dak) |
| SFD: | USDA257_c15770(dhaK1) |
| SAME: | SAMCFNEI73_pC0527(dhaK) |
| RHL: | LPU83_pLPU83c0761(dahK) |
| AALM: | LUX29_03940 LUX29_04675 |
| LCK: | HN018_01295 HN018_05120 |
| MPHL: | MPHLCCUG_02595(dhaK_1) |
| MAUU: | NCTC10437_04726(dhaK_1) |
| MTY: | MTOK_15430(lerK_1) MTOK_45770(derK) |
| MMAT: | MMAGJ_25120(dak) MMAGJ_63080(derK) |
| MYQ: | TUM20985_37800(derK) |
| SMAL: | SMALA_1062 SMALA_4772 |
| SAUO: | BV401_09105 BV401_27720 |
| SLUO: | PS467_25810 PS467_38435 |
| MPAL: | BO218_08360 BO218_09875 |
| MLV: | CVS47_02771(lerK_1) CVS47_02889(lerK_2) |
| MICS: | C1N74_01110 C1N74_02600 |
| MARK: | QUC20_00970 QUC20_02370 |
| MINV: | T9R20_01640 T9R20_02070 |
| MBET: | N8K70_06295 N8K70_13485 |
| MIMZ: | OED01_03100 OED01_13335 |
| RFS: | C1I64_09325 C1I64_14760 C1I64_17115 |
| ROE: | Q0F99_09575 Q0F99_16095 |
| RATH: | GSU68_01430 GSU68_07300 |
| CUM: | NI26_00150 NI26_11815 |
| CUB: | BJK06_01765 BJK06_07760 BJK06_13000 |
| CQF: | GBG65_02055 GBG65_07055 GBG65_13540 |
| CPOI: | OE229_03005 OE229_09045 |
| CPOM: | ACGH48_00330 ACGH48_07290 ACGH48_14205 |
| CPON: | N8D78_02635 N8D78_08750 N8D78_15305 |
| CURB: | QPJ90_04730 QPJ90_16555 |
| AMAU: | DSM26151_02390(lerK) |
| MSPO: | KXZ72_03860 KXZ72_07175 KXZ72_09175 |
| PLAP: | EAO79_00920 EAO79_04805 |
| ARR: | ARUE_c10550 ARUE_c18640 ARUE_c42630 |
| ARW: | MB46_01290 MB46_13980 |
| ARH: | AHiyo8_20760 AHiyo8_30930 AHiyo8_42860 |
| ARQ: | BWQ92_05660 BWQ92_11385 BWQ92_12020 BWQ92_14545 |
| ARN: | CGK93_05735(dhaL) CGK93_09920 |
| ARX: | ARZXY2_2903 ARZXY2_3962 |
| ARTH: | C3B78_01670 C3B78_10715(dhaL) |
| AOD: | Q8Z05_06865 Q8Z05_12395(dhaL) |
| ARTZ: | FCN77_02000 FCN77_04895(dhaL) FCN77_24720 |
| ARTT: | IG195_03055(dhaL) IG195_08120 |
| ARTN: | ABCW42_01320 ABCW42_17570 |
| PNV: | JMY29_05195(dhaL) JMY29_19760 |
| PAYJ: | HMI59_00330 HMI59_16160(dhaL) |
| PAYN: | HMI60_09435(dhaL) HMI60_19845 |
| PHRZ: | QN084_10505 QN084_17070(dhaL) |
| PANY: | ACPFL9_05545(dhaL) ACPFL9_09355 ACPFL9_09585 ACPFL9_10065 ACPFL9_20670 |
| ARZ: | AUT26_04885 AUT26_20025 |
| PSNI: | NIBR502771_00645(dhaL) NIBR502771_03590 |
| PSEY: | GU243_03925 GU243_05120 |
| POK: | SMD14_01875 SMD14_10685(dhaL) |
| PSLS: | KTR40_01830 KTR40_09815(dhaL) |
| PQA: | WHH00_16885 WHH00_17965 |
| PSNB: | NIBR502770_01825(dhaL) NIBR502770_19510 |
| SATK: | SA2016_3408 SA2016_3485 |
| CCYC: | SCMU_34600 SCMU_35420(derK) SCMU_39240 |
| SPUE: | AB5L97_16205 AB5L97_16500 |
| SEVR: | LWF01_14640 LWF01_18485 |
| RAIN: | Rai3103_05085 Rai3103_07410 |
| SEN: | SACE_4765(dak) SACE_5217(dak) |
| AMQ: | AMETH_2242(dak) AMETH_6525(dak) |
| ATHM: | L1857_13970 L1857_34730(dhaL) |
| PSEA: | WY02_03005 WY02_18480 |
| PAUT: | Pdca_04900(derK) Pdca_32710 |
| ACTA: | C1701_04345 C1701_24260 |
| ACAU: | ACOJVX_07025 ACOJVX_13600 |
| PMAD: | BAY61_13425 BAY61_13440 |
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| Reference |
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| Authors |
Huang H, Carter MS, Vetting MW, Al-Obaidi N, Patskovsky Y, Almo SC, Gerlt JA |
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| Title |
A General Strategy for the Discovery of Metabolic Pathways: d-Threitol, l-Threitol, and Erythritol Utilization in Mycobacterium smegmatis. |
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| Journal |
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| Sequence |
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| Other DBs |
| ExPASy - ENZYME nomenclature database: | 2.7.1.210 |
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| LinkDB |
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