Entry |
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Name |
pseudaminic acid cytidylyltransferase;
PseF
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Class |
Transferases;
Transferring phosphorus-containing groups;
Nucleotidyltransferases
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Sysname |
CTP:5,7-diacetamido-3,5,7,9-tetradeoxy-L-glycero-alpha-L-manno-nonulosonic acid cytidylyltransferase
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Reaction(IUBMB) |
CTP + 5,7-diacetamido-3,5,7,9-tetradeoxy-L-glycero-alpha-L-manno-2-nonulopyranosonic acid = diphosphate + CMP-5,7-diacetamido-3,5,7,9-tetradeoxy-L-glycero-alpha-L-manno-2-nonulopyranosonic acid [RN: R09843]
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Reaction(KEGG) |
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Substrate |
CTP [CPD: C00063];
5,7-diacetamido-3,5,7,9-tetradeoxy-L-glycero-alpha-L-manno-2-nonulopyranosonic acid
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Product |
diphosphate [CPD: C00013];
CMP-5,7-diacetamido-3,5,7,9-tetradeoxy-L-glycero-alpha-L-manno-2-nonulopyranosonic acid
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Comment |
Mg2+ is required for activity.
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History |
EC 2.7.7.81 created 2012
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Pathway |
ec00520 | Amino sugar and nucleotide sugar metabolism |
ec00541 | O-Antigen nucleotide sugar biosynthesis |
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Orthology |
K15899 | pseudaminic acid cytidylyltransferase |
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Genes |
PSHI: | SAMEA2665130_0847(neuA) |
VPL: | SA104470976_02487(pseF) |
GHO: | AL542_04205(pseF) AL542_05060(pseF) |
SALY: | E8E00_03885(pseF) E8E00_04310(pseF) |
PBC: | CD58_08190 CD58_08725 |
PPUU: | PputUW4_03893(pseF) |
PCAS: | LOY40_20460(pseF) LOY40_20975(pseF) |
PTW: | TUM18999_39450(rkpN) |
SSEM: | JYB85_12325(pseF) JYB85_12330(pseF) |
SZH: | K0H63_12975(pseF) K0H63_12980(pseF) |
AGAR: | OAG1_15530(rkpN) OAG1_16260 |
TIB: | THMIRHAM_04780(rkpN) |
PAUR: | FGL86_11220(pseF) FGL86_13920(pseF) |
CDIZ: | CEDIAZO_00255(neuA) |
ECOR: | SAMEA4412678_0511(neuA) |
BTRM: | SAMEA390648700508(neuA) |
HPO: | HMPREF4655_20568(pseF) |
HPX: | HMPREF0462_0383(pseF) |
HAC: | Hac_0995(neuA_fragment_1) |
HCL: | NCTC13205_00366(neuA) |
HPUL: | NCTC13154_00178(neuA) |
CJV: | MTVDSCj20_1306(pseF) |
CFV: | CFVI03293_1576(pseF) |
CAMP: | CFT03427_1508(pseF) |
CLR: | UPTC16701_1290(pseF) |
CLM: | UPTC16712_1312(pseF) |
CCOO: | ATE51_00942(legF_3) |
CAMR: | CAQ16704_1322(pseF) |
CHV: | CHELV3228_1547(pseF) |
CPIN: | CPIN18020_0092(pseF) |
CAMZ: | CVIC12175_0330(pseF) |
GBN: | GEOBRER4_36330(rkpN) |
DCB: | C3Y92_09205(pseF) C3Y92_20345(pseF) |
DSA: | Desal_0579 Desal_3632 |
DHY: | DESAM_20943 DESAM_21309 |
PPOR: | JCM14722_05430(rkpN) |
ABAM: | B1s21122_06190(pseF) |
» show all
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Reference |
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Authors |
Schoenhofen IC, McNally DJ, Brisson JR, Logan SM |
Title |
Elucidation of the CMP-pseudaminic acid pathway in Helicobacter pylori: synthesis from UDP-N-acetylglucosamine by a single enzymatic reaction. |
Journal |
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Sequence |
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Other DBs |
ExplorEnz - The Enzyme Database: | 2.7.7.81 |
ExPASy - ENZYME nomenclature database: | 2.7.7.81 |
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LinkDB |
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