Entry |
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Name |
thiazole synthase;
thiG (gene name)
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Class |
Transferases;
Transferring sulfur-containing groups;
Sulfurtransferases
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Sysname |
1-deoxy-D-xylulose 5-phosphate:thiol sulfurtransferase
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Reaction(IUBMB) |
1-deoxy-D-xylulose 5-phosphate + 2-iminoacetate + thiocarboxy-[sulfur-carrier protein ThiS] = 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + [sulfur-carrier protein ThiS] + 2 H2O [RN: R10247]
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Reaction(KEGG) |
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Substrate |
1-deoxy-D-xylulose 5-phosphate [CPD: C11437];
2-iminoacetate [CPD: C15809];
thiocarboxy-[sulfur-carrier protein ThiS] [CPD: C15814]
|
Product |
2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate [CPD: C20246];
[sulfur-carrier protein ThiS] [CPD: C15810];
H2O [CPD: C00001]
|
Comment |
H2S can provide the sulfur in vitro. Part of the pathway for thiamine biosynthesis.
|
History |
EC 2.8.1.10 created 2011, modified 2016
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Pathway |
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Orthology |
|
Genes |
ECOO: | ECRM13514_5111(thiG) |
ECOH: | ECRM13516_4847(thiG) |
ELR: | ECO55CA74_23010(thiG) |
ECW: | EcE24377A_4532(thiG) |
EDJ: | ECDH1ME8569_3850(thiG) |
ECOI: | ECOPMV1_02799(thiG) |
SEM: | STMDT12_C42970(thiG) |
SEEH: | SEEH1578_06980(thiG) |
SENJ: | CFSAN001992_12960(thiG) |
SDZ: | Asd1617_04926 Asd1617_04927 |
REE: | electrica_04815(thiG) |
RTG: | NCTC13098_06936(thiG) |
CLAP: | NCTC11466_04349(thiG) |
KIE: | NCTC12125_03514(thiG) |
METY: | MRY16398_53700(thiG) |
PSHI: | SAMEA2665130_3033(thiG) |
YPG: | YpAngola_A0451(thiG) |
YPI: | YpsIP31758_3856(thiG) |
SMW: | SMWW4_v1c02860(thiG) |
SERS: | SERRSCBI_01290(thiG) |
SFJ: | SAMEA4384070_0269(thiG) |
SOF: | NCTC11214_02088(thiG) |
EHD: | ERCIPSTX3056_678(thiG) |
PLF: | PANA5342_p10314(thiG) |
PVA: | Pvag_pPag30160(thiG) |
TPTY: | NCTC11468_00194(thiG) |
PHEI: | NCTC12003_00400(thiG) |
PRJ: | NCTC6933_00456(thiG) |
LRI: | NCTC12151_00407(thiG) |
APJ: | APJL_0525(thiG1) APJL_0526(thiG2) |
ALIG: | NCTC10568_01006(thiG) |
XFU: | XFF4834R_chr13380(thiG) |
XPH: | XppCFBP6546_17720(XppCFBP6546P_17720) |
XHD: | LMG31886_10780(thiG) |
LLZ: | LYB30171_00708(thiG) |
DJI: | CH75_00345 CH75_23430 |
VAU: | VANGNB10_cI2685c(thiG) |
VPL: | SA104470976_02676(thiG) |
VIB: | VspSTUT11_00260(thiG) |
VIS: | VspSTUT16_00290(thiG) |
PAEB: | NCGM1900_0386(thiG) |
PVD: | CFBP1590__4885(thiG) |
PPRC: | PFLCHA0_c58040(thiG) |
PMUD: | NCTC8068_05071(thiG) |
PFW: | PF1751_v1c51920(thiG) |
PPUU: | PputUW4_05127(thiG) |
PMAO: | PMYSY11_0433(thiG) PMYSY11_0932(thiG) |
PTW: | TUM18999_05210(thiG) |
PTAE: | NCTC10697_00286(thiG) |
PLAU: | I0D68_04675 I0D68_10855 |
PBB: | AKN87_07745 AKN87_08970 |
MSHE: | MAALD49_34850(thiG) |
PSYC: | DABAL43B_0296(thiG) |
ABK: | LX00_09270 LX00_12270 |
ABAU: | IX87_07445 IX87_19965 |
AVZ: | HWI77_09020 HWI77_10675 HWI77_17140 |
MCAT: | MC25239_01358(thiG) |
MCUN: | NCTC10297_01901(thiG) |
SCAA: | TUM17387_19040(thiG) |
CATE: | C2869_02305 C2869_04665 |
SALH: | HMF8227_02266(thiG) |
CBS: | COXBURSA331_A0440(thiG) |
LLG: | 44548918_01834(thiG) |
LCJ: | NCTC11976_01720(thiG) |
LSS: | NCTC12082_00537(thiG) |
MISZ: | MishRS11D_03870(thiG) |
TIB: | THMIRHAM_10940(thiG) |
TSE: | THMIRHAS_12220(thiG) |
TFRI: | Thiofri_03995(thiG) |
TNI: | TVNIR_3657(thiG_[H]) |
GAI: | IMCC3135_19900(thiG) |
THIC: | TspCOW1_21850(thiG) |
HBE: | BEI_0101(thiG1) BEI_2568(thiG2) |
HAAH: | HALA3H3_400021(thiG) |
HAXH: | J4377_02380 J4377_18035 |
HAXI: | HAALTHF_11810n(thiG) |
ALCA: | ASALC70_02140(thiG) |
MARS: | A8C75_00420 A8C75_19775 |
MRZ: | KDW95_15655 KDW95_19200 |
NJP: | NEJAP_0210 NEJAP_1515 |
AEL: | NCTC12917_00356(thiG) |
NMQ: | NMBM04240196_2013(thiG) |
NMZ: | NMBNZ0533_2004(thiG) |
NMX: | NMA510612_0383(thiG) |
NWE: | SAMEA3174300_1651(thiG) |
NZO: | SAMEA4504057_0038(thiG) |
NCI: | NCTC10296_00401(thiG) |
NCZ: | NCTC10294_01395(thiG) |
NANI: | NCTC12227_01937(thiG) |
CCAH: | DWG20_00065 DWG20_02325 |
PSE: | NH8B_0249 NH8B_1621 NH8B_3473(thiG) |
BMV: | BMASAVP1_A3226(thiG) |
BML: | BMA10229_A1775(thiG) |
BPM: | BURPS1710b_3707(thiG) |
BPL: | BURPS1106A_3737(thiG) |
BUE: | BRPE67_ACDS24660(thiG) |
PLG: | NCTC10937_00358(thiG) |
LMIR: | NCTC12852_02515(thiG) |
BUO: | BRPE64_ACDS25210(thiG) |
VTR: | MYVALT_E_00400(thiG) |
BTRM: | SAMEA390648700818(thiG) |
AXX: | ERS451415_00506(thiG) |
AFA: | UZ73_00920 UZ73_13300 |
AAQU: | D3M96_11505 D3M96_17310 |
PHN: | PAEH1_09835 PAEH1_10215 |
HAR: | HEAR0263(thiG1) HEAR0339(thiG2) |
MMS: | mma_0317(thiG1) mma_0386(thiG2) |
JAZ: | YQ44_17865 YQ44_23090 |
JAL: | BZG29_05080 BZG29_10055 |
JSV: | CNX70_05150 CNX70_10670 |
JAS: | FJQ89_22150 FJQ89_27150 |
JLV: | G3257_05235 G3257_10405 |
JAH: | JAB4_010750(thiG_1) JAB4_021530(thiG_2) |
JRI: | P9875_05140 P9875_10745 |
GLC: | JQN73_01180 JQN73_11920 |
METR: | BSY238_1328 BSY238_1402 |
URU: | DSM104443_00083(thiG) |
UPL: | DSM104440_00082(thiG) |
APET: | ToN1_13610(thiG1) ToN1_23620(thiG2) |
AZA: | AZKH_3152(thiG) AZKH_3810(thiG) AZKH_4454(thiG) |
AZI: | AzCIB_3468 AzCIB_3854 AzCIB_4394 |
AZD: | CDA09_18545 CDA09_21350 |
THU: | AC731_014880 AC731_016205 |
THAG: | CKCBHOJB_03553(thiG) |
AZQ: | G3580_01605 G3580_04400 |
ACOM: | CEW83_03205 CEW83_13920 |
FPHO: | SHINM1_019750(thiG) |
ERW: | ERWE_CDS_08040(thiG) |
ERG: | ERGA_CDS_07950(thiG) |
MESJ: | MJ8_15070 MJ8_40590 |
AMIS: | Amn_09940 Amn_46750 |
RBS: | RHODOSMS8_00742(thiG) |
SMEL: | SM2011_b20617(thiG) |
SFD: | USDA257_c22910(thiG) |
SAME: | SAMCFNEI73_pC1981(thiG) |
AGR: | AGROH133_08709(thiG) |
AVV: | RvVAT039_42160(thiG_2) |
AVF: | RvVAR031_34650(thiG_2) |
REC: | RHECIAT_PC0000247(thiG) |
REL: | REMIM1_PA00088(thiG) |
REP: | IE4803_PD00415(thiG) |
REI: | IE4771_PE00432(thiG) |
RTR: | RTCIAT899_PC03440(thiG) |
RGA: | RGR602_PC01289(thiG) |
RPHA: | AMC79_PD00260(thiG) |
RJG: | CCGE525_27690 CCGE525_34940 |
RAD: | CO657_22725 CO657_33115 |
RHID: | FFM81_028095 FFM81_031425 |
RBQ: | J2J99_29635 J2J99_33770 |
RBAN: | J2J98_27520 J2J98_29865 |
RRG: | J3P73_36325 J3P73_37180 |
RAW: | NE851_02205 NE851_08320 |
BIO: | BR141012304_10331(thiG) |
VGO: | GJW-30_1_02855(thiG) |
BHS: | BM1374165_00467(thiG) |
BBK: | BARBAKC583_0443(thiG) |
BTX: | BM1374166_00706(thiG) |
BEZ: | NCTC12898_00424(thiG) |
MAQU: | Maq22A_c24815(thiG) |
MTUN: | MTUNDRAET4_2160(thiG) |
FIL: | BN1229_v1_2302(thiG) |
FIY: | BN1229_v1_2301(thiG) |
BVY: | NCTC9239_01178(thiG) |
TSV: | DSM104635_01688(thiG) |
RLI: | RLO149_c039670(thiG) |
PHP: | PhaeoP97_00872(thiG) |
PPIC: | PhaeoP14_00827(thiG) |
OAR: | OA238_c18420(thiG1) OA238_c39770(thiG2) |
SINL: | DSM14862_01941(thiG) |
SPSE: | SULPSESMR1_04970(thiG) |
RMM: | ROSMUCSMR3_01915(thiG) |
AHT: | ANTHELSMS3_03946(thiG) |
MALU: | KU6B_49150(thiG_1) KU6B_56900(thiG_2) |
LVS: | LOKVESSMR4R_00070(thiG) LOKVESSMR4R_02493(thiG) |
SBIN: | SBA_ch1_36400(thiG) |
SSY: | SLG_16300(thiS_thiG) |
SPHB: | EP837_00898(thiG) EP837_03764 |
SPAG: | sphantq_02656(thiG) |
SFLA: | SPHFLASMR4Y_02644(thiG) |
HSH: | NHP194022_03280(thiG) |
HPUL: | NCTC13154_01350(thiG) |
CJV: | MTVDSCj20_1047(thiG) |
CFV: | CFVI03293_0075(thiG) |
CAMP: | CFT03427_0080(thiG) |
CCOC: | CCON33237_0910(thiG) |
CLR: | UPTC16701_1121(thiG) |
CLM: | UPTC16712_1152(thiG) |
CHV: | CHELV3228_1192(thiG) |
CAMZ: | CVIC12175_0607(thiG) |
PACO: | AACT_0304(thiG1) AACT_1258(thiG2) |
SMAB: | LN246_02740 LN246_13355 |
GBN: | GEOBRER4_06600(thiG) |
PCA: | Pcar_0339(thiG-1) Pcar_0609(thiG-2) |
PACE: | A6070_01745 A6070_12670 |
PPOR: | JCM14722_06410(thiG) |
BAZ: | BAMTA208_11755(thiG) |
BAE: | BATR1942_03490(thiG) |
BSON: | S101395_03586(thiG) |
BTHR: | YBT1520_04295(thiG) |
BTHU: | YBT1518_04675(thiG) |
BFD: | NCTC4823_00322(thiG) |
BSHI: | LGQ02_16080 LGQ02_16115 |
BACI: | B1NLA3E_07780(thiG) |
BGI: | BGM20_00070 BGM20_21150 |
CSPG: | LS684_02720 LS684_22805 |
PARG: | PspKH34_31130(thiG) |
HSHI: | MUO14_13760 MUO14_15275 |
BLEN: | NCTC4824_01716(thiG) |
ALKL: | MM271_07810 MM271_09110 |
SDP: | NCTC12225_02298(thiG) |
SPIC: | SAMEA4384060_0469(thiG) |
BAYD: | BSPP4475_10050(thiG) |
PPQ: | PPSQR21_027000(thiG) |
ACUR: | JZ785_03325 JZ785_17815 |
ACG: | AWM71_00510 AWM71_06640 |
CGEL: | psyc5s11_15140(thiG) |
CLO: | HMPREF0868_0737(thiG) |
BPRO: | PMF13cell1_01242(thiG) |
CSCI: | HDCHBGLK_02707(thiG) |
CHYL: | CE91St63_07320(thiG) |
ETM: | CE91St48_39540(thiG) |
PDF: | CD630DERM_17040(thiG) |
THYR: | P4S50_07435 P4S50_14155 |
CDIA: | CaldiYA01_20720(thiG) |
PIV: | NCTC13079_01344(thiG) |
MANA: | MAMMFC1_03515(thiG) |
PFAC: | PFJ30894_00305(thiG) |
MMAE: | MMARE11_06690(thiG) |
MBAI: | MB901379_00607(thiG) |
MHEK: | JMUB5695_04280(thiG) |
MKY: | IWGMT90018_07240(thiG) |
MPHL: | MPHLCCUG_04634(thiG) |
MTHN: | 4412656_00493(thiG) |
MAUU: | NCTC10437_00550(thiG) |
MFLV: | NCTC10271_04593(thiG) |
MSAL: | DSM43276_04097(thiG) |
MTER: | 4434518_00386(thiG) |
CDIP: | ERS451417_00038(thiG) |
CUN: | Cul210932_1501(thiG) |
CUQ: | Cul210931_1388(thiG) |
CUJ: | CUL131002_1422(thiG) |
CMIN: | NCTC10288_00904(thiG) |
CRL: | NCTC7448_00657(thiG) |
CAPP: | CAPP_02850(thiG1) CAPP_03225(thiG2) |
NFR: | ERS450000_04534(thiG) |
NAD: | NCTC11293_00322(thiG) |
NWL: | NWFMUON74_67510(thiG) |
NSPU: | IFM12276_59800(thiG) |
RHA: | RHA1_ro02188(thiG) RHA1_ro03594 |
ROP: | ROP_19030(thiG) ROP_33900(thiG) |
ROA: | Pd630_LPD06370 Pd630_LPD07981 |
RPY: | Y013_10120(thiG) Y013_14240(thiG) |
RCR: | NCTC10994_03429(thiG) |
RKO: | JWS14_11430 JWS14_19095 |
ROZ: | CBI38_07210(thiG) CBI38_30260(thiG) |
RPSK: | JWS13_25690 JWS13_34450 |
RHOJ: | JVH1_18660 JVH1_26345 |
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