Entry
Name
decaprenylphosphoryl-5-phosphoribose phosphatase;
Rv3807c (gene name)
Class
Hydrolases;
Acting on ester bonds;
Phosphoric-monoester hydrolases
BRITE hierarchy
Sysname
trans,octacis-decaprenylphospho-beta-D-ribofuranose 5-phosphate phosphohydrolase
Reaction(IUBMB)
trans,octacis-decaprenylphospho-beta-D-ribofuranose 5-phosphate + H2O = trans,octacis-decaprenylphospho-beta-D-ribofuranose + phosphate [RN:
R13371 ]
Reaction(KEGG)
Substrate
trans,octacis-decaprenylphospho-beta-D-ribofuranose 5-phosphate [CPD:
C20352 ];
H2O [CPD:
C00001 ]
Product
trans,octacis-decaprenylphospho-beta-D-ribofuranose [CPD:
C20368 ];
phosphate [CPD:
C00009 ]
Comment
The enzyme, studied from mycobacteria, in involved in the biosynthesis of trans,octacis-decaprenylphospho-beta-D-arabinofuranose, which serves in those organisms as the arabinofuranose donor for the biosynthesis of the cell wall polymers arabinogalactan and lipoarabinomannan.
History
EC 3.1.3.111 created 2024
Orthology
K27842 decaprenylphosphoryl-5-phosphoribose phosphatase
Genes
SLE : sle_28310(sle_28310)
» show all
Taxonomy
Reference
Authors
Wolucka BA.
Title
Biosynthesis of D-arabinose in mycobacteria - a novel bacterial pathway with implications for antimycobacterial therapy.
Journal
Sequence
Reference
Authors
Jiang T, Cai L, Zhao X, He L, Ma Y, Zang S, Zhang C, Li X, Xin Y.
Title
Functional identification of MSMEG_6402 protein from Mycobacterium smegmatis in decaprenylphosphoryl-D-arabinose biosynthesis.
Journal
Sequence
Other DBs
ExPASy - ENZYME nomenclature database: 3.1.3.111
LinkDB
All DBs