KEGG   ENZYME: 3.1.3.93
Entry
EC 3.1.3.93                 Enzyme                                 
Name
L-galactose 1-phosphate phosphatase;
VTC4 (gene name) (ambiguous);
IMPL2 (gene name) (ambiguous)
Class
Hydrolases;
Acting on ester bonds;
Phosphoric-monoester hydrolases
Sysname
beta-L-galactose-1-phosphate phosphohydrolase
Reaction(IUBMB)
beta-L-galactose 1-phosphate + H2O = L-galactose + phosphate [RN:R07674]
Reaction(KEGG)
R07674
Substrate
beta-L-galactose 1-phosphate [CPD:C15926];
H2O [CPD:C00001]
Product
L-galactose [CPD:C01825];
phosphate [CPD:C00009]
Comment
The enzyme from plants also has the activity of EC 3.1.3.25, inositol-phosphate phosphatase. The enzymes have very low activity with D-galactose 1-phosphate (cf. EC 3.1.3.94, D-galactose 1-phosphate phosphatase).
History
EC 3.1.3.93 created 2014
Pathway
ec00053  Ascorbate and aldarate metabolism
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K10047  inositol-phosphate phosphatase / L-galactose 1-phosphate phosphatase
K18649  inositol-phosphate phosphatase / L-galactose 1-phosphate phosphatase / histidinol-phosphatase
Genes
LCQ: 111679830
NMEA: 116425303
OSN: 115231278 118761388
ATH: AT3G02870(VTC4) AT4G39120(IMPL2)
ALY: 9304959 9320409
CRB: 17879544 17892437
CSAT: 104716190 104720823 104729217 104744369 104756767 104763907 104779537
EUS: EUTSA_v10021317mg EUTSA_v10025644mg
BRP: 103835143 103870884
BNA: 106353357 106361489 106406767 106443867 106447599 106453198 106453206
BOE: 106293897 106332503 106336071
RSZ: 108819822 108834826 108835903 108858996 108860365 108863576
THJ: 104807751 104812780 104815485
CPAP: 110810458 110812677
CIT: 102617016 102624075
CIC: CICLE_v10017102mg CICLE_v10028779mg
PVY: 116110131 116115806
MINC: 123213625 123219581
TCC: 18597288 18607733
GRA: 105769546 105776961 105795327
GHI: 107905686 107908803 107925171 107927829 107930396
GAB: 108453651 108460500 108474730
DZI: 111274054 111278317 111297018
EGR: 104445626 104453354
GMX: 100527811 100790820 100799849 100817591
GSJ: 114367021 114388732 114408443 114414466 114420225
PVU: PHAVU_003G084500g PHAVU_006G1424001 PHAVU_009G005100g
VRA: 106762079 106766982 106774484
VAR: 108330818 108332122 108341122
VUN: 114163228 114176501 114186922
CCAJ: 109788874 109804004 109808510
APRC: 113846571 113864744 113872664
MTR: MTR_2g026060 MTR_3g117220
CAM: 101496687 101502853
LJA: Lj1g3v3381210.1(Lj1g3v3381210.1) Lj1g3v3381210.2(Lj1g3v3381210.2) Lj4g3v0119960.1(Lj4g3v0119960.1) Lj6g3v1753250.1(Lj6g3v1753250.1)
ADU: 107459071 107459873 107466189 107482925
AIP: 107609158 107613726 107636682 107638701
AHF: 112703118 112703639 112706277 112722831 112741308 112765607 112771437 112796012
LANG: 109327793 109334908 109362898
FVE: 101290997 101293560
RCN: 112167446 112172659 112173712
PPER: 18768639 18779066
PMUM: 103326976 103335696
PAVI: 110768479 110771639
PDUL: 117624102 117637438
MDM: 103410485 103412081 103422491 103434428
PXB: 103936818 103939855 103943393 103962046 103963758
ZJU: 107426610 107434858 107435207
MNT: 21384156 21387774
CSV: 101205614 101206261 101217972
CMO: 103484661 103499699 103501724
BHJ: 120073866 120084238 120087575
MCHA: 111005250 111012748 111015418
CMAX: 111466554 111478849 111484263 111495495
CMOS: 111432599 111434392 111448992 111453628
CPEP: 111777092 111782853 111785922 111785977 111801415 111803740
RCU: 8284328 8285763
JCU: 105630124
HBR: 110657808 110664496 110667092
MESC: 110607532 110613017 110621875
POP: 112323239 18106030 7455821 7458515 7464008
PEU: 105114198 105120157 105136524 105142070
PALZ: 118030947 118044535 118049589 118049590 118052868 118058937
JRE: 108986922 109004560 109004567 109013338
QSU: 111986426 112020757
QLO: 115969608 115992494
TWL: 119988414 119990867 119997809 119998841 119998857 119999079 119999080 120005194 120005195 120006753
VVI: 100241840 100260677
VRI: 117909421 117923349
SLY: 101254644 544013(IMP3) 544014(IMP2) 544280(IMP1)
SPEN: 107002996 107004365 107014064 107016217 107025374
SOT: 102589172 102594242 102601018 102601710 107060700
CANN: 107840437 107851391 107870111
NTA: 107765195 107767520 107779235 107791846 107795668 107797228 107801850 107815806 107831188
NSY: 104216633 104225424 104241226 104244592
NTO: 104085856 104085994 104099465 104101224 104110594 104119600
NAU: 109207069 109209275 109213673 109214303 109242737
INI: 109162162 109165281
ITR: 116015736 116032181
SIND: 105168029 105169672 105175262
OEU: 111370675 111379676 111394577 111408057 111412108
EGT: 105957671 105962202 105973481
SSPL: 121749700 121753114 121773348 121777073 121788306 121789369 121804509
HAN: 110918067 110923354 110923355 110929164
ECAD: 122582030 122587288 122599474
LSV: 111875888 111918256
CCAV: 112501301 112522603
DCR: 108200932 108210045 108227607
CSIN: 114267151 114295583 114309059
BVG: 104900878 104904312 104907756
SOE: 110776252 110792578
CQI: 110687456 110698430 110705128 110731241
NNU: 104594191 104595613 104602512 104606566
MING: 122072599 122091979 122093141
TSS: 122639821 122643662 122657434 122661423
PSOM: 113288098 113302809 113308035
NCOL: 116246642 116259296
OSA: 4333347 4342620
DOSA: Os03t0587000-01(Os03g0587000) Os07t0191000-01(Os07g0191000)
OBR: 102705514 102719163
BDI: 100838580 100844148
ATS: 109738639 109768500
TDC: 119267870 119275762 119285949 119295985
TAES: 100415843 123060988 123069600 123078087 123086122 123097129
TUA: 125543533 125551778
SBI: 8063002 8085818
ZMA: 100280816 100283131
SITA: 101782298 101785092
SVS: 117836191 117854542
PVIR: 120650449 120691757 120706421
PHAI: 112874556 112894336
PDA: 103697686 103711558
EGU: 105036034 105058778
MUS: 103986548 103994951
DCT: 110107577 110108213
PEQ: 110031830 110032631 110032633
AOF: 109820443 109820444 109828921 109834403 109844836
ATR: 18426768 18446646
SMO: SELMODRAFT_232297 SELMODRAFT_234860 SELMODRAFT_270021 SELMODRAFT_81253
PPP: 112274227 112275224 112285229 112288452 112291813 112295845
CRE: CHLRE_06g278202v5 CHLRE_17g723550v5
VCN: VOLCADRAFT_109540 VOLCADRAFT_78931
MNG: MNEG_14064 MNEG_15624
CSL: COCSUDRAFT_17466 COCSUDRAFT_47143
CVR: CHLNCDRAFT_34254 CHLNCDRAFT_58575
APRO: F751_5675
OLU: OSTLU_31726 OSTLU_38679
OTA: OT_ostta05g02610 OT_ostta05g04730
BPG: Bathy03g03320 Bathy03g05420
MIS: MICPUN_108257 MICPUN_79551
MPP: MICPUCDRAFT_14899 MICPUCDRAFT_15690
CME: CYME_CMH095C
GSL: Gasu_46960
CCP: CHC_T00007726001
SRE: PTSG_02105
DDI: DDB_G0281239(impa1)
DFA: DFA_07272(impa1)
ACAN: ACA1_065900 ACA1_149190
TPS: THAPSDRAFT_31846 THAPS_17443
NGD: NGA_0525100(IMPA)
AAF: AURANDRAFT_4399
EHX: EMIHUDRAFT_66633 EMIHUDRAFT_73492
GTT: GUITHDRAFT_118366
SFO: Z042_05565
EAM: EAMY_0371(cbbF)
EAY: EAM_3049
PSX: DR96_1548
PVC: G3341_02225
PFQ: QQ39_16035
PFUW: KF707C_6590
POJ: PtoMrB4_08570
PTW: TUM18999_09060
MBS: MRBBS_3410
MPQ: ABA45_16125
HSI: BOX17_08770
HAA: A5892_19205
ORB: IPMB12_01120(hisN)
NBA: CUN60_10265
IOD: EJO50_05305
IFL: C1H71_01010
JEU: BJP62_03295
DEE: HQN60_00930(hisN)
CHIZ: HQ393_02540(hisN)
CFON: HZU75_13295(hisN)
BGD: bgla_2g07740
BGO: BM43_4393(hisN)
BPX: BUPH_02537
PTRO: G5S35_16370(hisN)
PPK: U875_16645
PPNO: DA70_08540
PPNM: LV28_22100
PRB: X636_17825
PPUL: RO07_16500
PSPU: NA29_20675
PAPI: SG18_15335
PVE: UC34_07700
POX: MB84_12075
PTX: ABW99_02530
PFG: AB870_18405
PNR: AT302_26305
PAND: DRB87_07005(hisN)
PFIB: PI93_020130(hisN)
CARI: FNU76_18085
AXY: AXYL_06485(hisN)
AXO: NH44784_022471
AXN: AX27061_6040
AXX: ERS451415_06174(hisN)
ADT: APT56_00085
AIS: BUW96_25570
ACHR: C2U31_04600(hisN)
ADY: HLG70_21855(hisN)
PACR: FXN63_17400(hisN)
VAP: Vapar_0980
VPE: Varpa_1044
VPD: VAPA_1c10340
VAA: AX767_06295
VBO: CKY39_02195 CKY39_04935(hisN)
VAM: C4F17_14250(hisN)
JAB: VN23_03845
NMU: Nmul_A2147
AZO: azo3824(imp)
AOA: dqs_3976
AZR: CJ010_22170(hisN)
SCL: sce9228
SCU: SCE1572_52125
MRM: A7982_07537
AAK: AA2016_2670
EAD: OV14_b0273
EAH: FA04_29105
ARA: Arad_9808
ATA: AWN88_01670 AWN88_11220
AGR: AGROH133_15232
ATF: Ach5_50450
SHZ: shn_16820 shn_32325
KAI: K32_09740
BRS: S23_45720
BEL: BE61_37680
LNE: FZC33_15620
APRA: G3A50_08120(hisN)
MEA: Mex_1p4121
MDI: METDI4713
MEX: Mext_3749
MCH: Mchl_4044
MPO: Mpop_4004
MZA: B2G69_00560
MOR: MOC_5479
META: Y590_18620
MPHY: MCBMB27_04239
METD: C0214_20870
METX: A3862_07900
BBAR: RHAL1_02536
NTD: EGO55_08040
AUA: M673_21010
AALA: IGS74_09015(hisN)
AALM: LUX29_09895(hisN)
RBM: TEF_04735
LAP: ACP90_07605
LABT: FIU93_13260(hisN2)
LAGG: B0E33_19665
RUA: D1823_19445
RUT: FIU92_18920(hisN2)
LEJ: ETW24_20920
CID: P73_2855
YAN: AYJ57_18910
SULI: C1J05_07730
SPSE: SULPSESMR1_04425(hisN)
AHT: ANTHELSMS3_01360
SAGU: CDO87_22070(hisN)
HAT: RC74_13375
PLIA: E4191_17145
RSU: NHU_03960
RHM: B5V46_00820
SEDI: EBB79_05315
PSEB: EOK75_08845
PAED: G5B38_03235
PAMO: BAR1_04870
THAS: C6Y53_04525
ZMN: Za10_1684
ZMM: Zmob_1605
ZMB: ZZ6_1576
ZMI: ZCP4_1631
ZMC: A265_01629(hisN)
ZMR: A254_01629(hisN)
ZMP: Zymop_1579
NAR: Saro_0975
NPP: PP1Y_AT35844
NPN: JI59_10445
NRE: BES08_15375
NOV: TQ38_016175
NOT: C7W88_01230
NOR: FA702_09935
NGF: FRF71_06925
NOG: GKE62_10185
NDR: HT578_15540(hisN)
SAL: Sala_2941
SPHK: SKP52_21100
SPHP: LH20_21470
SMAG: AN936_20840
SMAZ: LH19_17825 LH19_24260
STER: AOA14_07720
SGI: SGRAN_0337(hisN)
SPHQ: BWQ93_16275
SPHO: C3E99_18145(hisN)
SPHX: E5675_19705(hisN)
SPHU: SPPYR_3826
SWI: Swit_2434
SPHD: HY78_13345
RDI: CMV14_00015(hisN)
SPHM: G432_10615
STAX: MC45_17495
SPHI: TS85_21090
SSAN: NX02_23200
SNJ: A7E77_08285
SMY: BJP26_04135
SPAN: AWL63_02930
SKR: BRX40_02950
SPLM: BXU08_13275
SPLK: AV944_01995
SPKC: KC8_12960
SPHC: CVN68_13845(hisN)
SPHF: DM480_07485
SPHA: D3Y57_12550(hisN)
SPAU: DRN02_013135
SLAN: GV829_04165(hisN)
SPAP: H3Z74_21290(hisN)
SPAI: FPZ24_16030(hisN)
SARI: H5J25_18365(hisN)
SSUA: FPZ54_14155(hisN)
SJP: SJA_C1-03250
SINB: SIDU_14490
SCH: Sphch_2336
SSY: SLG_00610
SYB: TZ53_10185
SBD: ATN00_02855
SPMI: K663_00550
SPHB: EP837_01351
SPHR: BSY17_1667(hisN)
SPHT: K426_17945
SHYD: CJD35_03705
SYA: A6768_19830
SCLO: SCLO_1020980
SPYG: YGS_C1P2491
SUFL: FIL70_16225(hisN)
SBAR: H5V43_13180(hisN)
SAMI: SAMIE_1028210
SPPH: KFK14_01230(hisN)
CIJ: WG74_02340
SPHG: AZE99_15405
SFLA: SPHFLASMR4Y_02407(hisN)
SPHY: CHN51_05710(hisN)
SPHL: LPB140_02320
BLAS: BSY18_2785(hisN)
BFW: B5J99_04890
SPZR: G5C33_02600(hisN)
HGN: E6W36_03970
PALG: HFP57_11620
PARJ: J4G78_11245(hisN)
PHAO: HF685_10880(hisN)
SMIC: SmB9_02970
SAND: H3309_03155(hisN)
AEP: AMC99_02691
ALB: AEB_P0699
ALH: G6N82_09685(hisN)
AAY: WYH_02419(hisN)
AMX: AM2010_2096
ANH: A6F65_00299(hisN)
ADO: A6F68_00585(hisN)
TFV: IDJ81_04015(hisN)
CNA: AB433_14170
CMAN: A9D14_00350
ERY: CP97_02750
EGN: BMF35_a0798
EFV: CHH26_01670
QCI: NCF85_14140(hisN)
ELI: ELI_13805
ELQ: Ga0102493_111164
ERK: CD351_01355(hisN)
ERR: DVR09_03295(hisN)
ERF: FIU90_01350(hisN)
EMV: HQR01_06300(hisN)
PNS: A9D12_03840
PORL: BG023_11202
PHZ: CHX26_03545(hisN)
POT: E2E27_04485(hisN)
GSP: IGS75_00330
GBE: GbCGDNIH1_1991
GBH: GbCGDNIH2_1991
GBS: GbCGDNIH4_1991
ACR: Acry_0645
AMV: ACMV_12240
GXY: GLX_05430
GXL: H845_1656
KNA: B0W47_02250
KEU: S101446_00924
KRE: GWK63_08360
APT: APA01_11900
APW: APA42C_11900
APF: APA03_11900
APU: APA07_11900
APG: APA12_11900
APQ: APA22_11900
APX: APA26_11900
APZ: APA32_11900
APK: APA386B_2711(suhB)
AASC: A4S02_03895
AOY: EOV40_005500
ABG: Asbog_01130
KBA: A0U89_07785
RGI: RGI145_01480
RMUC: FOB66_18895
NCH: A0U93_03135
COQ: D9V35_04740
COMM: GN303_04540
NEH: E3E11_07715
SWF: E3E12_06980
EBLA: JGUZn3_15230(hisN)
LCK: HN018_04795
KHA: IFJ82_07960
SHUM: STHU_52210
SVC: STVA_52110
STEL: STAQ_47320
AZL: AZL_004300
ALI: AZOLI_0288
ABS: AZOBR_40268
ABQ: ABAZ39_01950
ABF: AMK58_11900
ATI: AL072_06150
AHU: A6A40_01145
AZT: TSH58p_13495(hisN)
AZM: DM194_00730(hisN)
AZZ: DEW08_15625(hisN)
AOZ: HUE56_21630(hisN)
NAO: Y958_01815(hisN)
NCB: C0V82_16950
SKT: IGS68_01755(hisN)
SMUC: JL100_024920(hisN)
SROE: JL101_023720(hisN)
RRF: F11_16215
RCE: RC1_3403(suhB)
RPM: RSPPHO_01506
MAG: amb4169
MGY: MGMSRv2__3872
MGRY: MSR1_25420(hisN)
MAGX: XM1_0424
MAGN: WV31_04510
TMO: TMO_3189
THAL: A1OE_348
EFK: P856_212(suhB)
FER: FNB15_03335(hisN)
HTQ: FRZ44_04410
HADH: FRZ61_04660 FRZ61_31510
DEX: HWD60_10860(hisN)
DVN: HQ394_03025(hisN)
TXI: TH3_18585
THAC: CSC3H3_17800(hisN)
TII: DY252_02965 DY252_02970(hisN)
MAGQ: MGMAQ_0109
APC: HIMB59_00008360
APB: SAR116_1485
MPH: MLP_02270
CYA: CYA_2769
CYB: CYB_2462
MAR: MAE_61680
MPK: VL20_2239
MIQ: B5D77_11725
MVZ: myaer102_33820
CYT: cce_3293(suhB)
CWA: CwatDRAFT_2135
CYP: PCC8801_1470
CYH: Cyan8802_1497
CYC: PCC7424_0430
CYJ: Cyan7822_5575
PLP: Ple7327_4576
CEO: ETSB_0389(suhB)
CER: RGRSB_0344(suhB)
 » show all
Reference
1  [PMID:15550539]
  Authors
Laing WA, Bulley S, Wright M, Cooney J, Jensen D, Barraclough D, MacRae E
  Title
A highly specific L-galactose-1-phosphate phosphatase on the path to ascorbate biosynthesis.
  Journal
Proc Natl Acad Sci U S A 101:16976-81 (2004)
DOI:10.1073/pnas.0407453101
  Sequence
[ag:AAV49506]
Reference
2  [PMID:19339506]
  Authors
Torabinejad J, Donahue JL, Gunesekera BN, Allen-Daniels MJ, Gillaspy GE
  Title
VTC4 is a bifunctional enzyme that affects myoinositol and ascorbate biosynthesis in plants.
  Journal
Plant Physiol 150:951-61 (2009)
DOI:10.1104/pp.108.135129
  Sequence
[ath:AT3G02870 AT4G39120]
Reference
3  [PMID:20023146]
  Authors
Petersen LN, Marineo S, Mandala S, Davids F, Sewell BT, Ingle RA
  Title
The missing link in plant histidine biosynthesis: Arabidopsis myoinositol monophosphatase-like2 encodes a functional histidinol-phosphate phosphatase.
  Journal
Plant Physiol 152:1186-96 (2010)
DOI:10.1104/pp.109.150805
  Sequence
[ath:AT4G39120]
Other DBs
ExplorEnz - The Enzyme Database: 3.1.3.93
IUBMB Enzyme Nomenclature: 3.1.3.93
ExPASy - ENZYME nomenclature database: 3.1.3.93
BRENDA, the Enzyme Database: 3.1.3.93
LinkDB

DBGET integrated database retrieval system