KEGG   ENZYME: 3.1.7.3
Entry
EC 3.1.7.3                  Enzyme                                 
Name
monoterpenyl-diphosphatase;
bornyl pyrophosphate hydrolase;
monoterpenyl-pyrophosphatase
Class
Hydrolases;
Acting on ester bonds;
Diphosphoric-monoester hydrolases
Sysname
monoterpenyl-diphosphate diphosphohydrolase
Reaction(IUBMB)
a monoterpenyl diphosphate + H2O = a monoterpenol + diphosphate [RN:R03016]
Reaction(KEGG)
R03016 > R08396 R08529
Substrate
monoterpenyl diphosphate [CPD:C03517];
H2O [CPD:C00001]
Product
monoterpenol [CPD:C00863];
diphosphate [CPD:C00013]
Comment
A group of enzymes with varying specificity for the monoterpenol moiety. One has the highest activity on sterically hindered compounds such as (+)-bornyl diphosphate; another has highest activity on the diphosphates of primary allylic alcohols such as geraniol.
History
EC 3.1.7.3 created 1984
Pathway
ec00902  Monoterpenoid biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Reference
1  [PMID:42357]
  Authors
Croteau R, Karp F.
  Title
Biosynthesis of monoterpenes: hydrolysis of bornyl pyrophosphate, an essential step in camphor biosynthesis, and hydrolysis of geranyl pyrophosphate, the acyclic precursor of camphor, by enzymes from sage (Salvia officinalis).
  Journal
Arch Biochem Biophys 198:523-32 (1979)
DOI:10.1016/0003-9861(79)90527-7
Other DBs
ExplorEnz - The Enzyme Database: 3.1.7.3
IUBMB Enzyme Nomenclature: 3.1.7.3
ExPASy - ENZYME nomenclature database: 3.1.7.3
BRENDA, the Enzyme Database: 3.1.7.3
LinkDB

KEGG   REACTION: R08396
Entry
R08396                      Reaction                               
Name
geranyl-diphosphate diphosphohydrolase
Definition
Geranyl diphosphate + H2O <=> Geraniol + Diphosphate
Equation
Reaction class
RC00017  C00341_C01500
Enzyme
3.1.7.3         3.1.7.11
Pathway
rn00902  Monoterpenoid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 3. Hydrolase reactions
  3.1  Acting on ester bonds
   3.1.7  Diphosphoric-monoester hydrolases
    3.1.7.3
     R08396  Geranyl diphosphate + H2O <=> Geraniol + Diphosphate
    3.1.7.11
     R08396  Geranyl diphosphate + H2O <=> Geraniol + Diphosphate
IUBMB reaction hierarchy [BR:br08202]
 3. Hydrolase reactions
  3.1.7.3
   R03016  Monoterpenyl diphosphate <=> Monoterpenol
    R08396  Geranyl diphosphate <=> Geraniol
Orthology
K20979  geranyl diphosphate diphosphatase [EC:3.1.7.11]
Other DBs
RHEA: 32682
LinkDB

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