Entry
Name
baicalin-beta-D-glucuronidase;
baicalinase
Class
Hydrolases;
Glycosylases;
Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
BRITE hierarchy
Sysname
5,6,7-trihydroxyflavone-7-O-beta-D-glucupyranosiduronate glucuronosylhydrolase
Reaction(IUBMB)
baicalin + H2O = baicalein + D-glucuronate [RN:
R09533 ]
Reaction(KEGG)
Substrate
Product
Comment
The enzyme also hydrolyses wogonin 7-O-beta-D-glucuronide and oroxylin 7-O-beta-D-glucuronide with lower efficiency [4]. Neglegible activity with p-nitrophenyl-beta-D-glucuronide [2].
History
EC 3.2.1.167 created 2011
Orthology
K20833 baicalin-beta-D-glucuronidase
Reference
Authors
Ikegami F, Matsunae K, Hisamitsu M, Kurihara T, Yamamoto T, Murakoshi I
Title
Purification and properties of a plant beta-D-glucuronidase form Scutellaria root.
Journal
Sequence
Reference
2
Authors
Zhang C, Zhang Y, Chen J, Liang X.
Title
Purification and characterization of baicalin-beta-D-glucuronidase hydrolyzing baicalin to baicalein from fresh roots of Scutellaria viscidula Bge.
Journal
Proc Biochem 40:1911-1915 (2005)
Reference
Authors
Sasaki K, Taura F, Shoyama Y, Morimoto S
Title
Molecular characterization of a novel beta-glucuronidase from Scutellaria baicalensis georgi.
Journal
Sequence
Reference
4
Authors
Morimoto S, Harioka T, Shoyama Y.
Title
Purification and characterization of flavone-specific beta-glucuronidase from callus cultures of Scutellaria baicalensis Georgi.
Journal
Planta 195:535-540 (1995)
Other DBs
ExPASy - ENZYME nomenclature database: 3.2.1.167
LinkDB
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