ENZYME: 3.5.1.39
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Entry
EC 3.5.1.39 Enzyme
Name
alkylamidase
Class
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amides
BRITE hierarchy
Sysname
N-methylhexanamide amidohydrolase
Reaction(IUBMB)
N-methylhexanamide + H2O = hexanoate + methylamine [RN:
R03620
]
Reaction(KEGG)
R03620
Reaction
Substrate
N-methylhexanamide [CPD:
C02722
];
H2O [CPD:
C00001
]
Product
hexanoate [CPD:
C01585
];
methylamine [CPD:
C00218
]
Comment
The enzyme hydrolyses N-monosubstituted and N,N-disubstituted amides, and there is some activity towards primary amides. It has little or no activity towards short-chain substrates.
History
EC 3.5.1.39 created 1976
Reference
1 [PMID:
5141674
]
Authors
Chen PR, Dauterman WC.
Title
Alkylamidase of sheep liver.
Journal
Biochim Biophys Acta 250:216-23 (1971)
DOI:
10.1016/0005-2744(71)90137-9
Other DBs
ExplorEnz - The Enzyme Database:
3.5.1.39
IUBMB Enzyme Nomenclature:
3.5.1.39
ExPASy - ENZYME nomenclature database:
3.5.1.39
BRENDA, the Enzyme Database:
3.5.1.39
CAS:
62213-19-8
LinkDB
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DBGET
integrated database retrieval system
