KEGG   ENZYME: 3.5.1.63
Entry
EC 3.5.1.63                 Enzyme                                 
Name
4-acetamidobutyrate deacetylase
Class
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amides
Sysname
4-acetamidobutanoate amidohydrolase
Reaction(IUBMB)
4-acetamidobutanoate + H2O = acetate + 4-aminobutanoate [RN:R01987]
Reaction(KEGG)
R01987;
(other) R02276
Substrate
4-acetamidobutanoate [CPD:C02946];
H2O [CPD:C00001]
Product
acetate [CPD:C00033];
4-aminobutanoate [CPD:C00334]
Comment
Also acts on N-acetyl-beta-alanine and 5-acetamidopentanoate.
History
EC 3.5.1.63 created 1989
Pathway
ec00310  Lysine degradation
ec00330  Arginine and proline metabolism
ec01100  Metabolic pathways
Reference
1
  Authors
Haywood GW, Large PJ.
  Title
4-Acetamidobutyrate deacetylase in the yeast Candida boidinii grown on putrescine or spermidine as sole nitrogen source and its probable role in polyamine catabolism.
  Journal
J Gen Microbiol 132:7-14 (1986)
Other DBs
ExplorEnz - The Enzyme Database: 3.5.1.63
IUBMB Enzyme Nomenclature: 3.5.1.63
ExPASy - ENZYME nomenclature database: 3.5.1.63
BRENDA, the Enzyme Database: 3.5.1.63
CAS: 102347-82-0
LinkDB

KEGG   REACTION: R01987
Entry
R01987                      Reaction                               
Name
4-acetamidobutanoate amidohydrolase
Definition
4-Aminobutanoate + Acetate <=> 4-Acetamidobutanoate + H2O
Equation
C00334 + C00033 <=> C02946 + C00001
Reaction class
RC00096  C00334_C02946
RC00300  C00033_C02946
Enzyme
3.5.1.63
Pathway
rn00330  Arginine and proline metabolism
rn01100  Metabolic pathways
Module
M00135  GABA biosynthesis, eukaryotes, putrescine => GABA
Brite
Enzymatic reactions [BR:br08201]
 3. Hydrolase reactions
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.63
     R01987  4-Aminobutanoate + Acetate <=> 4-Acetamidobutanoate + H2O
Other DBs
RHEA: 15900 18904
LinkDB

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