KEGG   ENZYME: 3.6.1.6
Entry
EC 3.6.1.6                  Enzyme                                 
Name
nucleoside diphosphate phosphatase;
nucleoside-diphosphatase;
thiaminpyrophosphatase;
UDPase;
inosine diphosphatase;
adenosine diphosphatase;
IDPase;
ADPase;
adenosinepyrophosphatase;
guanosine diphosphatase;
guanosine 5'-diphosphatase;
inosine 5'-diphosphatase;
uridine diphosphatase;
uridine 5'-diphosphatase;
type B nucleoside diphosphatase;
GDPase;
CDPase;
nucleoside 5'-diphosphatase;
type L nucleoside diphosphatase;
NDPase;
nucleoside diphosphate phosphohydrolase
Class
Hydrolases;
Acting on acid anhydrides;
In phosphorus-containing anhydrides
Sysname
nucleoside-diphosphate phosphohydrolase
Reaction(IUBMB)
a nucleoside diphosphate + H2O = a nucleoside phosphate + phosphate [RN:R00329]
Reaction(KEGG)
Substrate
nucleoside diphosphate [CPD:C00454];
H2O [CPD:C00001]
Product
nucleoside phosphate [CPD:C01329];
phosphate [CPD:C00009]
Comment
The enzyme, which appears to be limited to metazoa, acts on multiple nucleoside diphosphates as well as on D-ribose 5-diphosphate. Specificity depends on species and isoform.
History
EC 3.6.1.6 created 1961
Pathway
ec00230  Purine metabolism
ec00240  Pyrimidine metabolism
ec01100  Metabolic pathways
Orthology
K01511  ectonucleoside triphosphate diphosphohydrolase 5/6
K12304  soluble calcium-activated nucleotidase 1
K12305  ectonucleoside triphosphate diphosphohydrolase 4
Genes
HSA124583(CANT1) 955(ENTPD6) 957(ENTPD5) 9583(ENTPD4)
PTR453027(ENTPD5) 458146(ENTPD6) 464056(ENTPD4) 468345(CANT1)
PPS100969324(ENTPD4) 100974659(CANT1) 100975707(ENTPD5) 100985458(ENTPD6)
GGO101126430(ENTPD6) 101142724(ENTPD5) 101148704(ENTPD4) 115934947(CANT1)
PON100433776(ENTPD4) 100449249(ENTPD6) 100454763(CANT1) 103892385(ENTPD5)
NLE100601352(CANT1) 100603393(ENTPD6) 100604246(ENTPD4) 100604959(ENTPD5)
MCC698503(ENTPD5) 705663(ENTPD6) 710935(CANT1) 717197(ENTPD4)
MCF102118635(ENTPD5) 102127579(CANT1) 102133506(ENTPD6) 102139183(ENTPD4)
MTHB126929297 126939220 126959522 126961249
CSAB103215479(ENTPD4) 103229320(ENTPD5) 103243671(CANT1) 103247059(ENTPD6)
CATY105577637(CANT1) 105579208(ENTPD4) 105581961(ENTPD6) 105590839(ENTPD5)
PANU100997844(ENTPD6) 101006558(ENTPD4) 101007099(ENTPD5) 101011745(CANT1)
TGE112609605(CANT1) 112628796(ENTPD5) 112629739(ENTPD4) 112633166(ENTPD6)
RRO104657284(ENTPD4) 104661029(ENTPD6) 104677031(CANT1) 104677558(ENTPD5)
RBB108522410(ENTPD6) 108534172(CANT1) 108534899(ENTPD5) 108537903(ENTPD4)
TFN117066783(CANT1) 117068345(ENTPD6) 117069350(ENTPD5) 117093471(ENTPD4)
PTEH111520725(ENTPD5) 111527249(ENTPD6) 111534949(CANT1) 111545705(ENTPD4)
CJC100394992(ENTPD5) 100395619(ENTPD4) 100402589(CANT1) 100412828(ENTPD6)
SBQ101035743(ENTPD5) 101044293(CANT1) 101048728(ENTPD6) 101049938(ENTPD4)
CSYR103249698(CANT1) 103253960(ENTPD5) 103265918(ENTPD4) 103271158(ENTPD6)
MMUR105857169(ENTPD4) 105858515(ENTPD5) 105860649(ENTPD6) 105866699(CANT1)
LCAT123621214(CANT1) 123622453(ENTPD6) 123626496(ENTPD4) 123646876(ENTPD5)
OGA100947642(ENTPD5) 100956343(ENTPD6) 100959410(CANT1) 100965530(ENTPD4)
MMU100862375(Entpd4b) 12497(Entpd6) 12499(Entpd5) 67464(Entpd4) 76025(Cant1)
MCAL110305208(Cant1) 110306789(Entpd5) 110309119 110309260 110312620(Entpd6)
MPAH110318176(Entpd6) 110324875(Entpd5) 110325109(Entpd4) 110331475(Cant1)
RNO246272(Cant1) 314312(Entpd5) 361063(Entpd4) 85260(Entpd6)
MCOC116078228(Cant1) 116079569(Entpd5) 116084518(Entpd4) 116091132(Entpd6)
MUN110546974(Entpd5) 110550202(Cant1) 110554941(Entpd4) 110565692(Entpd6)
CGE100751454(Entpd5) 100765414(Entpd6) 100767250(Cant1) 100771637(Entpd4)
MAUA101823100(Entpd4) 101825732(Cant1) 101832979(Entpd6) 101836947(Entpd5)
PLEU114698256(Entpd5) 114702693(Entpd4) 114708956(Cant1) 114709545(Entpd6)
MORG121436207(Cant1) 121452123(Entpd5) 121460296(Entpd6) 121461457(Entpd4)
MFOT126488394 126494637 126500432 126515129
AAMP119800288(Entpd4) 119812504(Cant1) 119815521(Entpd6) 119820018(Entpd5)
NGI103747295(Cant1) 103747371(Entpd5) 103748013(Entpd4) 103748530(Entpd6)
HGL101700645(Entpd4) 101703881(Entpd5) 101708374(Cant1) 101717001(Entpd6)
CPOC100379248(Entpd6) 100721163(Entpd5) 100725891(Cant1) 100730248(Entpd4)
CCAN109682707(Cant1) 109688404(Entpd5) 109689699 109689706 109699832(Entpd6)
DORD105980115(Cant1) 105983604(Entpd5) 105993696(Entpd6) 105999436(Entpd4)
DSP122096133(Entpd6) 122096592(Cant1) 122106476 122118655(Entpd5) 122121801 122123491(Entpd4)
NCAR124976689 124977193 124980279 124981011 124982278
OCU100341814(ENTPD5) 100342665(ENTPD6) 100345399(ENTPD4) 100352568(CANT1)
OPI101516743(ENTPD5) 101520524(CANT1) 101531158(ENTPD4) 101531995(ENTPD6)
TUP102473435(ENTPD5) 102477259(ENTPD6) 102482611(CANT1) 102499936(ENTPD4)
CFA480384(ENTPD5) 485564(ENTPD6) 486117(ENTPD4)
CLUD112657004(ENTPD5) 112668852(ENTPD6) 112669740(ENTPD4)
VVP112926807(ENTPD4) 112927264(ENTPD5) 112933230(ENTPD6)
VLG121478911(ENTPD6) 121493073(ENTPD5) 121497306(ENTPD4)
AML100470325(ENTPD5) 100475785(ENTPD4) 109488325(CANT1)
UMR103671253(ENTPD5) 103681915(ENTPD6)
UAH113248357(ENTPD6) 113269982(ENTPD4) 113270347(ENTPD5)
UAR123777399(ENTPD4) 123798995(ENTPD5) 123800938(ENTPD6)
ELK111148573 111156630 111156836 111160259
LLV125092875 125105686 125108428
MPUF101671753(ENTPD6) 101672836(ENTPD5) 101692474(ENTPD4) 106003413(CANT1)
ORO101363791(ENTPD6) 101363814(ENTPD4) 101374973(ENTPD5)
EJU114216321(CANT1) 114217473(ENTPD4) 114224517(ENTPD6)
ZCA113925043(ENTPD4) 113937882(ENTPD6)
MLX118002657(ENTPD5) 118011165(ENTPD6) 118022092(ENTPD4)
NSU110571435(ENTPD5) 110588459(ENTPD4) 110589983(ENTPD6)
FCA101085117(ENTPD4) 101090270(ENTPD5) 101090852(ENTPD6)
PYU121012582(ENTPD6) 121032035(ENTPD5) 121039856(ENTPD4)
PBG122469312(ENTPD5) 122472209(ENTPD4) 122497550(ENTPD6)
LRUF124503648 124512043 124520490
PTG102952970(ENTPD4) 102958703(ENTPD5) 102966424(ENTPD6) 102968784(CANT1)
PPAD109253818(ENTPD5) 109259576(ENTPD6) 109276834(CANT1) 109277329(ENTPD4)
AJU106974434(ENTPD5) 106980293(ENTPD6) 106981113(ENTPD4)
HHV120226244(ENTPD6) 120228156(CANT1) 120231963(ENTPD5) 120239466(ENTPD4)
BTA508097(ENTPD6) 518086(CANT1) 531411(ENTPD4) 533096(ENTPD5)
BOM102264690(ENTPD6) 102272160(CANT1) 102278224(ENTPD5) 102283172(ENTPD4)
BIU109563130(ENTPD4) 109565341(ENTPD5) 109568065(ENTPD6) 109574131(CANT1)
BBUB102398753(ENTPD4) 102401428(CANT1) 102404661(ENTPD6) 102407508(ENTPD5)
CHX102174488(ENTPD6) 102177094(CANT1) 102177626(ENTPD4) 102187956(ENTPD5)
OAS101104845(ENTPD6) 101105824(ENTPD5) 101120555(ENTPD4) 101122609(CANT1)
ODA120852734(ENTPD5) 120865731(ENTPD4) 120866816(CANT1) 120869490(ENTPD6)
CCAD122432073(ENTPD4) 122437863(CANT1) 122443848(ENTPD5) 122448376(ENTPD6)
SSC100154506(ENTPD5) 100155254(ENTPD4) 100620107(CANT1) 100626131(ENTPD6)
CFR102506563(ENTPD4) 102507072(CANT1) 102513093(ENTPD6) 102524265(ENTPD5)
CBAI105065590(CANT1) 105068963(ENTPD4) 105074958(ENTPD5) 105083187(ENTPD6)
CDK105086117(ENTPD5) 105099848(ENTPD6) 105102460(ENTPD4) 105105800(CANT1)
VPC102526884(ENTPD5) 102534071(ENTPD6) 102540135(ENTPD4) 102545255(CANT1)
BACU103001237(ENTPD4) 103008563(ENTPD5) 103016453(CANT1) 103017331(ENTPD6)
LVE103069753(CANT1) 103072735(ENTPD6) 103076010(ENTPD5) 103090675(ENTPD4)
OOR101274835(ENTPD4) 101279340(ENTPD5) 101285084(ENTPD6) 101286631(CANT1)
DLE111176268(ENTPD5) 111182745(CANT1) 111185033(ENTPD6) 111185430(ENTPD4)
PCAD102981075(ENTPD4) 102982949(ENTPD6) 102989446(CANT1) 102990767(ENTPD5)
PSIU116740561(ENTPD6) 116745867(CANT1) 116748373(ENTPD5) 116755291(ENTPD4)
ECB100053982(ENTPD4) 100056466(ENTPD5) 100057043(ENTPD6) 100057405(CANT1)
EPZ103544225(ENTPD6) 103550751(ENTPD4) 103551442(CANT1) 103560626(ENTPD5)
EAI106827399(ENTPD6) 106827629(ENTPD4) 106827678(ENTPD5) 106845398(CANT1)
MYB102243929(ENTPD6) 102251396(CANT1) 102251399(ENTPD4) 102262670(ENTPD5)
MYD102756459(ENTPD5) 102761731(ENTPD6) 102767239(ENTPD4) 102768384(CANT1)
MMYO118657787(ENTPD4) 118657949(ENTPD5) 118663518(ENTPD6) 118671990(CANT1)
MLF102419532(ENTPD5) 102425478(ENTPD4) 102432978(ENTPD6)
MNA107532051(CANT1) 107533484(ENTPD5) 107536083(ENTPD4) 107541889(ENTPD6)
PKL118704521(CANT1) 118707957(ENTPD6) 118715423(ENTPD5) 118725820(ENTPD4)
HAI109372329(ENTPD4) 109378612(ENTPD6) 109381563(ENTPD5) 109383715(CANT1)
DRO112298696(CANT1) 112305070(ENTPD4) 112311427(ENTPD5)
SHON118975001(ENTPD4) 118976764(ENTPD5) 118993045(ENTPD6) 118999559(CANT1)
AJM119036263(ENTPD5) 119054679(ENTPD4) 119058625(CANT1)
PDIC114493302(ENTPD5) 114502629(ENTPD4) 114504004(CANT1) 114504111 114506037(ENTPD6)
PHAS123807966(ENTPD5) 123814716(ENTPD6) 123816742(CANT1) 123828225(ENTPD4)
MMF118615174(ENTPD4) 118618731(ENTPD6) 118629033(ENTPD5) 118634515(CANT1)
RFQ117015815(ENTPD6) 117023799(ENTPD5) 117037794(ENTPD4)
PALE102879280(ENTPD6) 102879747(ENTPD4) 102885970(ENTPD5) 102886824(CANT1)
PGIG120586969(ENTPD6) 120600315(CANT1) 120606651(ENTPD4)
PVP105299241 105304071(ENTPD6) 105304713(ENTPD4)
RAY107499915(ENTPD6) 107507623(ENTPD5) 107509207(ENTPD4) 107510071(CANT1)
MJV108388639(ENTPD6) 108393181(ENTPD4) 108409337(ENTPD5)
TOD119231856(ENTPD6) 119232277(CANT1) 119233606(ENTPD4) 119239375(ENTPD5)
SARA101538536(ENTPD4) 101538587(ENTPD6) 101545499(ENTPD5) 101556034(CANT1)
LAV100662574(ENTPD4) 100670458(CANT1) 100670899(ENTPD6) 100671455(ENTPD5)
TMU101341093 101344215 101346902 101351128
DNM101413456(ENTPD5) 101424961 101433129(ENTPD6) 101447553(CANT1)
MDO100021277(ENTPD4) 100024118(ENTPD5) 100026552(CANT1) 100033226(ENTPD6)
GAS123234792(ENTPD6) 123235847(ENTPD5) 123236656(ENTPD4) 123244128(CANT1)
SHR100914260(ENTPD4) 100934101(CANT1) 100934821(ENTPD5) 100935093(ENTPD6)
PCW110193938(CANT1) 110208339(ENTPD5) 110209096(ENTPD6) 110218362(ENTPD4)
OAA100075558(ENTPD4) 100088014(CANT1) 100088379(ENTPD6)
GGA416708(ENTPD6) 419531(ENTPD4) 423343(ENTPD5) 430103(CANT1)
PCOC116229389(ENTPD5) 116231490(ENTPD6) 116232535(CANT1) 116238379(ENTPD4)
MGP100539042(ENTPD5) 100541241(ENTPD6) 100546671(CANT1) 100550411(ENTPD4)
CJO107310965(ENTPD6) 107315087(ENTPD5) 107322204(CANT1) 107323626(ENTPD4)
NMEL110387090(ENTPD4) 110395638(ENTPD6) 110400927(ENTPD5) 110407357(CANT1)
APLA101794207(ENTPD5) 101798772(ENTPD6)
ACYG106038827(ENTPD5) 106044765(ENTPD6) 106046784(CANT1) 106049706(ENTPD4)
AFUL116487878(ENTPD6) 116489667(ENTPD5) 116496521(CANT1) 116499462(ENTPD4)
TGU100219260(CANT1) 100220000(ENTPD5) 100224923(ENTPD6) 100227643(ENTPD4)
LSR110472436(CANT1) 110472809(ENTPD6) 110477215(ENTPD5) 110483778(ENTPD4)
SCAN103819741(CANT1) 103821292(ENTPD6) 103824429(ENTPD4) 103826533(ENTPD5)
PMOA120497165(ENTPD4) 120500391(ENTPD5) 120500910(ENTPD6) 120505513(CANT1)
OTC121331928(ENTPD5) 121338236(CANT1) 121346386(ENTPD6) 121346763(ENTPD4)
PRUF121353926(ENTPD6) 121356044(ENTPD5) 121363444(CANT1) 121365990(ENTPD4)
GFR102033650(ENTPD5) 102035287(ENTPD6) 102035478(CANT1) 102044536(ENTPD4)
FAB101811604(CANT1) 101814014(ENTPD6) 101814697(ENTPD4) 101820141(ENTPD5)
PHI102101855(ENTPD4) 102106545(ENTPD5) 102108288(CANT1) 102109632(ENTPD6)
PMAJ107202034(ENTPD6) 107205897(ENTPD5) 107212434(CANT1) 107213958(ENTPD4)
CCAE111937476(CANT1) 111938755(ENTPD4) 111942216(ENTPD6) 111945531(ENTPD5)
CCW104685058(ENTPD5) 104694876(ENTPD4) 104696652(ENTPD6) 104698209(CANT1)
CBRC103613237(CANT1) 103614902(ENTPD4) 103617474(ENTPD6) 103620865(ENTPD5)
ETL114055983(ENTPD5) 114060374(CANT1) 114066757(ENTPD6) 114068765(ENTPD4)
ZAB102070148 102071276(ENTPD5) 102074278(ENTPD6) 106629946
ACHL103804913(ENTPD6) 103805615(ENTPD5) 103811143(CANT1) 103812205(ENTPD4)
FPG101910519(ENTPD4) 101911075(ENTPD5) 101912651(CANT1) 101920667(ENTPD6)
FCH102047237(ENTPD6) 102056974(ENTPD5) 102057968(CANT1) 102058083(ENTPD4)
CLV102084705(ENTPD5) 102084729(CANT1) 102092438(ENTPD4) 102095170(ENTPD6)
EGZ104123518(ENTPD4) 104128771(ENTPD6) 104133292(ENTPD5) 104133521(CANT1)
NNI104015047(CANT1) 104015795(ENTPD6) 104019528(ENTPD4) 104020984(ENTPD5)
PLET104614449(ENTPD6) 104617919(ENTPD5) 104620695(CANT1) 104622740(ENTPD4)
PCRI104024189(ENTPD6) 104024933(CANT1) 104025351(ENTPD5) 104025895(ENTPD4)
ACUN113478395(ENTPD6) 113480570(ENTPD5) 113488116(ENTPD4)
TALA104355939(ENTPD6) 104363503(CANT1) 104363903(ENTPD4) 104367742(ENTPD5)
PADL103912956(ENTPD5) 103913096(ENTPD4) 103917408(CANT1) 103923101(ENTPD6)
AFOR103893478(ENTPD6) 103893808(ENTPD4) 103896887(CANT1) 103900106(ENTPD5)
ACHC115341001(CANT1) 115350137(ENTPD4) 115350434(ENTPD6) 115352770(ENTPD5)
HALD104311922(ENTPD5) 104318163(ENTPD6) 104318668(ENTPD4) 104325989(CANT1)
CCRI104156151(CANT1) 104157258(ENTPD4) 104157643(ENTPD6) 104159497(ENTPD5)
CSTI104557862(CANT1) 104558847(ENTPD4) 104562728(ENTPD6)
EHS104513227(ENTPD6) 104513918(ENTPD4) 104514504(ENTPD5)
CMAC104473532(CANT1) 104473859(ENTPD6) 104474367(ENTPD5) 104479976(ENTPD4)
MUI104534565(ENTPD6) 104535093(ENTPD4) 104544094(ENTPD5)
FGA104070189(ENTPD6) 104073609(CANT1) 104078629(ENTPD4) 104081902(ENTPD5)
GSTE104256218(CANT1) 104257257(ENTPD6) 104257899(ENTPD5) 104262784(ENTPD4)
LDI104341023(ENTPD6) 104343356(ENTPD4) 104344060(ENTPD5) 104347108(CANT1)
MNB103770318(ENTPD4) 103772375(ENTPD6) 103780390(ENTPD5)
OHA104333604(ENTPD5) 104339561(ENTPD4)
NNT104399885(ENTPD6) 104400337(ENTPD5) 104405253(ENTPD4) 104407241(CANT1)
DPUB104297802(ENTPD4) 104297876(CANT1) 104300902(ENTPD6) 104308201(ENTPD5)
PGUU104457549(ENTPD5) 104459881(ENTPD4) 104466985(CANT1) 104468869(ENTPD6)
ACAR104518804(ENTPD5) 104518928(ENTPD6) 104522830(CANT1) 104530981(ENTPD4)
AVIT104268058(ENTPD6) 104271843(ENTPD5) 104275528(CANT1) 104279974(ENTPD4)
CVF104285650(ENTPD4) 104288197(ENTPD5) 104290142(CANT1) 104295131(ENTPD6)
AAM106482860(ENTPD5) 106485706(ENTPD4) 106487146(CANT1) 106494176(ENTPD6)
AROW112973568(ENTPD6) 112973692(ENTPD4) 112974778(CANT1) 112977900(ENTPD5)
NPD112945326(CANT1) 112949328(ENTPD6) 112950930(ENTPD4) 112957951(ENTPD5)
TGT104579807(ENTPD5) 104580100(ENTPD4)
DNE112985530(ENTPD6) 112991620(CANT1) 112995428(ENTPD5) 112996732(ENTPD4)
SCAM104138183(ENTPD4) 104141549(ENTPD5) 104142939(ENTPD6) 104150340(CANT1)
ASN102377226(ENTPD5) 102382407(ENTPD4) 102384786(ENTPD6) 102387737(CANT1)
AMJ102558177(ENTPD5) 102558389(ENTPD4) 102558883(CANT1) 102561141(ENTPD6)
CPOO109314889(CANT1) 109319446(ENTPD6) 109321207(ENTPD5) 109324563(ENTPD4)
GGN109288590(ENTPD4) 109296168(CANT1) 109296673(ENTPD6) 109298639(ENTPD5)
PSS102446197(ENTPD5) 102448778(ENTPD6) 102457836(ENTPD4) 102457946(CANT1)
CMY102933100(ENTPD6) 102944019(ENTPD4) 102944229(ENTPD5) 102947400(CANT1)
CPIC101936718(CANT1) 101938561(ENTPD6) 101947170(ENTPD4) 101951614(ENTPD5)
TST117872955(ENTPD4) 117874112(ENTPD6) 117876409(ENTPD5) 117887638(CANT1)
CABI116819108(ENTPD6) 116826015(ENTPD4) 116835884(CANT1) 116837504(ENTPD5)
MRV120383780(CANT1) 120398378(ENTPD4) 120400964(ENTPD6) 120403093(ENTPD5)
ACS100555642(entpd5) 100561218(entpd6) 100562980(entpd4) 100563392(cant1)
PVT110072190(ENTPD4) 110079567(ENTPD6) 110086369(ENTPD5) 110090286(CANT1)
SUND121919229(ENTPD5) 121921217 121922789(CANT1) 121935050(ENTPD4) 121935147
PBI103048410(ENTPD6) 103051878(CANT1) 103054355(ENTPD5) 103056945(ENTPD4)
PMUR107284111(ENTPD6) 107290491(ENTPD5) 107292203(CANT1) 107293144(ENTPD4)
CTIG120297812(ENTPD6) 120308779(CANT1) 120311793(ENTPD5) 120312901(ENTPD4)
TSR106539303(ENTPD5) 106543734(CANT1) 106551417(ENTPD6)
PGUT117663014(CANT1) 117665813(ENTPD5) 117671543(ENTPD6) 117676977(ENTPD4)
VKO123018093(CANT1) 123022825(ENTPD6) 123026859(ENTPD5) 123027108(ENTPD4)
PMUA114585218(ENTPD4) 114589083(CANT1) 114592126(ENTPD5) 114594838(ENTPD6)
ZVI118079715(CANT1) 118082003(ENTPD5) 118083042(ENTPD6) 118097012(ENTPD4)
GJA107107286(ENTPD4) 107111965(ENTPD6) 107115314(CANT1) 107123169(ENTPD5)
STOW125426518(ENTPD5) 125429636(CANT1) 125441916(ENTPD4) 125446053(ENTPD6)
XLA108712719(entpd4.S) 379060(cant1.L) 495422(entpd4.L) 734187(entpd6.L) 734189(entpd5.L)
XTR394537(cant1) 677731(entpd4) 677734(entpd5) 677735(entpd6)
NPR108792480(ENTPD4) 108796391(CANT1) 108801077(ENTPD6) 108802467(ENTPD5)
RTEM120918883(CANT1) 120921007(ENTPD5) 120933083(ENTPD4) 120937636(ENTPD6)
BBUF120982290(ENTPD5) 120986157(ENTPD4) 120998808(ENTPD6) 121003821(CANT1)
BGAR122921549(ENTPD5) 122927398(ENTPD4) 122934982 122940305(CANT1)
DRE406558(cant1a) 436692(entpd4) 445201(cant1b) 550560(entpd6) 556849(entpd5a)
SRX107710847 107717107 107717471 107732154(cant1) 107732262 107733529 107739256 107747713 107756050
SANH107662622 107663308 107664449 107671134 107671255 107678413 107698120 107700370 107702024 107703876 107704388
SGH107552124 107553047 107553130 107559455(entpd4) 107559893 107564575 107567625 107571310 107576405 107583517 107586906
CCAR109045504 109047172 109085724 109089248 109089258 109095040 109097183 109107877(entpd6) 109108470 109108506 109108632 109109047
CAUA113039676 113047564 113053115 113055551 113055558 113060525 113077291 113094116 113094553 113107450(entpd4) 113111285 113117077 113117199
PPRM120476052(entpd5a) 120476221 120476222 120478357(entpd6) 120481308(entpd4) 120491972(cant1b)
MAMB125243242(cant1a) 125256135(cant1b) 125268798(entpd6) 125269015(entpd5a) 125280412(entpd4)
IPU108257529(entpd5b) 108265395(entpd4) 108269455(entpd5a) 108270072(entpd6) 108270889(cant1b)
PHYP113533379(entpd4) 113536555(cant1) 113538697(entpd5) 113545023(entpd6) 113545268
SMEO124390084(entpd5a) 124390518(entpd6) 124391247(cant1b) 124400133(entpd4)
TFD113640547(entpd6) 113644529(entpd5b) 113646478(entpd4) 113653445(cant1b) 113659348(entpd5a)
AMEX103031064(entpd6) 103034776 103035312 103035579(entpd4) 103043327(entpd5)
EEE113575230 113578168(entpd4) 113582176(entpd6) 113587035(entpd5) 113589693 113590766
TRU101061741 101063748 101065382(entpd6) 101070342(entpd5) 101076188
TNGGSTEN00018574G001 GSTEN00020303G001 GSTEN00020435G001 GSTEN00025012G001 GSTEN00026236G001 GSTEN00032296G001
LCO104919812 104921415(entpd5) 104922273 104925070(cant1) 104934622(entpd4) 104936920(entpd6)
NCC104950180 104960639 104960923(entpd5) 104967224
CGOB115003481 115010325 115012382 115013384(entpd4) 115027257(entpd5)
ELY117248339(entpd6) 117252930(entpd4) 117255351(cant1b) 117266991(entpd5a) 117267787(cant1a) 117270818
EFO125879806(cant1a) 125885651(cant1b) 125890566(entpd4) 125897286 125900686(entpd5a) 125903439(entpd6)
PLEP121941847(cant1b) 121944757(entpd4) 121954000(entpd5a) 121955604 121956498(cant1a)
SLUC116034472 116035579(entpd5a) 116042598(cant1b) 116052845 116053884(entpd4) 116057924 116059696(cant1a)
ECRA117936194(entpd5a) 117936661(cant1b) 117944243(entpd4) 117958652(cant1a) 117961343
ESP116669691(entpd5) 116690193(entpd4) 116702564 116704974 116706769 116706978
PFLV114546974(entpd5) 114555913(entpd4) 114569538(cant1) 114570446 114572072(entpd6) 114572703
GAT120807988 120821090(entpd6) 120825244 120827966(cant1a) 120830489(entpd4) 120833328(entpd5a)
PPUG119194567 119214159(entpd6) 119218259(cant1b) 119220836(cant1a) 119224560(entpd4) 119227182(entpd5a)
MSAM119884213 119890217(cant1a) 119891821(entpd4) 119899551(cant1b) 119909282 119910218(entpd5a) 119911360
CUD121508371(cant1b) 121509997(entpd4) 121511139(entpd6) 121521224 121526285(entpd5a) 121529488(cant1a)
ALAT119005047(entpd5a) 119012096(entpd5b) 119013931(cant1a) 119019736(entpd4) 119021648(cant1b) 119033489(entpd6)
MZE101466916(cant1) 101470512(entpd6) 101474178 101480607 101481315 101483235(entpd5) 112430046
ONL100695989 100701747(cant1) 100704298(entpd6) 100704637 100707381(entpd4) 102078803
OAU116310234(entpd4) 116312797(entpd6) 116325233(cant1a) 116330955(cant1b) 116332227 116335865(entpd5a)
OLA101158069 101165115(entpd5) 101171168(cant1) 101172088(entpd4) 101172636 101173329(entpd6)
OML112137424(cant1b) 112145443(entpd5a) 112146028(cant1a) 112148744(entpd4) 112158000(entpd5b) 112161370(entpd6)
XMA102222595(entpd5) 102222865(cant1) 102222913(entpd6) 102226763 102226786 102236347(entpd4)
XCO114134105 114138047(entpd6) 114144359 114155002(entpd4) 114158335 114159986(cant1)
XHE116708839 116712920(entpd6) 116719745 116730184(entpd4) 116734420 116734887(cant1)
PRET103457894 103459024(entpd5) 103465407 103468847(cant1) 103470498(entpd4) 103477400(entpd6)
PFOR103131327 103136188 103140961(cant1) 103145661(entpd4) 103150496 103152661
PLAI106936696(cant1) 106941346 106951258 106954549 106961553 106963216(entpd4)
PMEI106908879 106917535 106920084(cant1) 106922130 106927908(entpd4) 106932879
GAF122821810(cant1a) 122824988(entpd5b) 122827974(entpd4) 122829587(cant1b) 122842840(entpd6) 122846388(entpd5a)
CVG107083186(cant1) 107086537(entpd6) 107090774 107090868 107092407(entpd5) 107093855(entpd4)
CTUL119778279(cant1a) 119783280(cant1b) 119783993(entpd4) 119784169 119787560(entpd5a) 119794265(entpd6)
GMU124859437(entpd6) 124863431 124863998 124867953(cant1b) 124877232(entpd4) 124882119(entpd5b) 124884948(entpd5a)
NFU107372628 107374543 107377059 107378096 107392375(entpd5) 107392387 107393774(entpd4)
KMR108231867 108232039 108236422(cant1b) 108236441(entpd4) 108241365(cant1a) 108250727(entpd6)
ALIM106518670 106520453(entpd4) 106520746(entpd5) 106521437 106528449(entpd6) 106535213
NWH119413614(entpd4) 119413629(entpd6) 119418091 119421658(cant1a) 119422832 119427758(entpd5a)
AOCE111564630 111578657(entpd4) 111578737 111579424 111581964 111583163 111585858
MCEP124997248 124998976 125003798(cant1b) 125012672(entpd4) 125018508(entpd6) 125023425(entpd5a)
CSEM103381017 103387028(entpd6) 103392811(cant1) 103397390(entpd5) 103398226(entpd4)
POV109627738 109632571 109633878(entpd4) 109638727(cant1) 109644144 109644676
SSEN122760626 122763161(entpd6) 122763162 122769976(entpd4) 122771485(cant1b) 122782671(entpd5a) 122784056 122785187(cant1a)
HHIP117755947(entpd5a) 117758345(entpd5b) 117765688(cant1a) 117766134(cant1b) 117768451(entpd4) 117775183(entpd6)
HSP118099456 118114926(entpd4) 118116410(entpd5a) 118118865(entpd6) 118119853(cant1b) 118123085(cant1a)
LCF108873841 108878709 108891815 108892557(entpd5a) 108896911(entpd5b) 108902724(cant1a)
SDU111224199(entpd6) 111225967(entpd5) 111227038(cant1) 111227880 111229434 111238571
SLAL111646221(entpd6) 111657780(cant1) 111663168(entpd5) 111663935(entpd4) 111666685 111672659
XGL120784520(cant1a) 120789428 120795813(entpd5a) 120796401(entpd6) 120800241(cant1b) 120805129(entpd4)
HCQ109513178(entpd5) 109517726(cant1) 109525218 109527423
BPEC110155498(entpd5) 110165198 110166507 110168045 110168259 110168394 110169856(entpd4)
MALB109955156(entpd5) 109957004(entpd4) 109957848 109962192 109972252(cant1) 109972990(entpd6)
BSPL114841997(entpd6) 114848243(entpd5a) 114849339 114860518(cant1a) 114861937(entpd4) 114865619(cant1b)
SASA100195480(cant1) 100196687(enp6) 106564354 106571572 106576718(entpd6) 106579862 106585564 106591143 106592000 106592979(entpd5) 106606400 106606402 106608092 106611031
STRU115147544 115153114 115162308 115164549 115171117 115171815 115172595 115174500 115184177 115193883(entpd6) 115207194
OTW112217833 112239798(cant1a) 112242090(cant1b) 112248456(entpd4) 112250557 112253607(entpd6) 112256711(entpd5a) 112261764 121838604
OMY110485510 110485511 110487066 110487067 110497901 110502374(entpd6) 110505564(entpd5a) 110522461 110525636 110529861 110532586 110536003(entpd4)
OGO123990984 123995296 124002295 124020825 124026058 124034342 124034915 124038192 124045270(entpd5a)
ONE115107985 115111574 115113296 115128175 115138523 115139205 115146211
SALP111951883 111957398 111963027 111968714 111972739 111974196 111978275 112072024 112079760
SNH120017590 120018138 120019357 120023289(entpd5a) 120024063 120041437 120041641 120041691 120046523 120059995 120063216 120066754
CCLU121530871 121534283(cant1b) 121538810 121544362 121548679 121551214 121552727 121553746 121568711 121569636 121584817
ELS105012018 105013048(cant1) 105014029(entpd4) 105017536 105025521(entpd6) 105026440(entpd5)
SFM108918097(entpd6) 108922499 108929552(entpd4) 108930275 108930744 108941444(entpd5)
PKI111839609(cant1) 111844472 111846605 111849011(entpd6) 111852445(entpd5) 111857528(entpd4)
AANG118206477(entpd5a) 118206879(entpd4) 118216839(cant1a) 118217617 118218325 118221485 118230418
LOC102683882(entpd6) 102689065(cant1) 102691606(entpd5) 102691919(entpd4)
PSPA121295646(cant1b) 121296255 121302434 121307574 121315772 121316873 121324947 121329816
ARUT117397948 117403244 117410722 117412059 117422041 117423361 117424519(cant1a) 117962499
LCM102345277(CANT1) 102354256(ENTPD6) 102364599(ENTPD4) 102364924(ENTPD5)
CMK103175547(cant1a) 103179204(entpd6) 103186794(entpd5a) 103188915 103191300(entpd4)
RTP109918689 109923459(entpd4) 109923666 109927023 109931464(cant1)
BFO118413090 118425776 118428743
BBEL109471006 109482888 109485251
CIN100181442 100181727
SCLV120335897 120335901 120336934 120344495
SPU115918638 576801 580175 587808
APLC110976233 110979908 110981511
SKO100369288 100374157 100378249
DMEDmel_CG3059(NTPase) Dmel_CG5276(CG5276)
DER6541376 6553859
DSE6606824 6613174
DSIDsimw501_GD18755(Dsim_GD18755) Dsimw501_GD22791(Dsim_GD22791)
DYADyak_GE14979 Dyak_GE26097
DAN6497724 6499659
DSR110185987 110186657
DPO4802814 4816633
DPE6594544 6596417
DMN108155497 108163588
DWI6646760 6646894
DGR6562799 6568465
DMODmoj_GI10286 Dmoj_GI17567
DAZ108609199 108610979
DNV108659708 115562618
DHE111602209 111604562 115482801
DVI6632365 6634237
CCAT101453750 101459816
BOD106616043 106618121
RZE108355026 108372677 108377396
MDE101895011 101895369
SCAC106085959 106092068
LCQ111678516 111687285
LSQ119602324 119607981
HIS119650880 119658760
AGAAgaP_AGAP001217 AgaP_AGAP009265
ACOZ120952836 120955698
AARA120896114 120901418
ASTE118507950 118514631
AAG110677770 5566799 5568212
AALB109402110 109422742 115254978
CQUCpipJ_CPIJ005468 CpipJ_CPIJ006723
CPII120412972 120418609
CNS116336607 116336611 116337150 116340399 116342853 116345895 116346146 116348817 116352510
BCOO119066308 119076687
AME550987 551373 726444
ACER108001951 108002375
ALAB122713579 122714476
BIM100743904 100748276
BBIF117214671 117216936
BVK117231539 117240647
BVAN117153154 117163065
BTER100645603 100647321
BPYO122573263 122576794
CCAL108626285 108629338
OBB114875748 114879743
MGEN117220987 117222407
NMEA116425319 116430711
CGIG122397171 122401861
SOC105193921 105201971
MPHA105833777 105838267
AEC105149168 105150421
ACEP105623966 105627089
PBAR105424644 105427742
VEM105561611 105567792
HST105186558 105186857
DQU106745202 106747546
CFO105258280 105258683
FEX115233539 115242777
LHU105671908 105678914
PGC109852671 109853124
OBO105278155 105285209
PCF106783710 106788039
PFUC122522596 122524802
VPS122631287 122638150
NVI100120729 100678150
CSOL105361226 105368179
TPRE106654454 106658784 106660046
MDL103572261 103576337
CGLO123262754 123268843
FAS105263795 105266367
DAM107036816 107048721
AGIF122858221 122860835
LHT122500210 122501023 122501040 122501042
CCIN107264185 107265609
TCA658576 662718
DPA109538940 109547015
SOY115881107 115886086 115886105
ATD109601047 109603184
CSET123309610 123316334
AGB108905369 108912716
LDC111504595 111510985
NVL108559357 108569757
APLN108739562 108745101
PPYR116168815 116171313 116178387 116179673
OTU111418128 111426614
BMOR101739670 101746124
BMAN114240420 114240653
MSEX115443613 115446836 115452212
DPLKGM_205738
BANY112042806 112053376
NIQ126770586
PMAC106713040 106717491
PPOT106107309
PXU106117535 106119034
PRAP110996233 110999403
ZCE119832552 119836148
HAW110371757 110376954
HZE124632998 124639330
TNL113494755 113503203
SLIU111359969 111363441
OFU114365331 114365373
PXY105386376 105395579 105398481
CFEL113372271 113389424 113389526 113389533 113389540
API100162387 100166504 103308894
DNX107169359 107170676 107171755
AGS114125033 114125927 114131092 114131093
RMD113551123 113554506 113556152 113556652 113561078
BTAB109033477 109037793
DCI103509559 103516223 103516319 103522838
CLEC106669807 106669828
HHAL106688646
NLU111064320
PHUPhum_PHUM421050 Phum_PHUM604210
FOC113203849 113209190
TPAL117646607 117653844
ZNE110826916 110839117
CSEC111863790 111864873
FCD110842722 110849692 110853370
DPXDAPPUDRAFT_188560 DAPPUDRAFT_307947
DMK116927425 123474573
PVM113803114 113812035
PJA122255343 122259192
PCHN125042928 125043799 125046929
HAME121861064
PCLA123767745 123773869
PTRU123509895 123512633
HAZT108664585 108673061
EAF111701448 111712960 111715885
LSM121122701 121122824 121122825 121125845 121126596
PPOI119103077 119113731 119114124
ISCIscW_ISCW018254
DSV119453293
RSAN119400189
RMP119180151
VDE111245407 111246290 111247973
VJA111259705 111265153 111269707
TUT107367568
DPTE113788983 113794534 113796790 113797804 113797960
DFR124490474 124494111
CSCU111620477 111623391 111631433
PTEP107438620 107438621 107438622 107438623 107448313
SDM118193348 118202524
CELCELE_F08C6.6(apy-1) CELE_K08H10.4(uda-1) CELE_R07E4.4(mig-23) CELE_ZK563.7(ZK563.7)
CBRCBG_11542(Cbr-uda-1) CBG_14198 CBG_14784(Cbr-mig-23) CBG_16731
BMYBM_BM3194(Bma-apy-1)
LOALOAG_01305
NAINECAME_04539 NECAME_04976 NECAME_04977 NECAME_05333 NECAME_05334 NECAME_15316 NECAME_18038 NECAME_18602
TSPTsp_09215 Tsp_09582
HROHELRODRAFT_133471 HELRODRAFT_69675 HELRODRAFT_77501
LGILOTGIDRAFT_123541
PCAN112556813 112565036 112570778
BGT106056870 106057153
GAE121366368 121378913
HRF124117433 124144565 124145971
HRJ124260872 124281942 124282124
CRG105341080 105347053
MYI110449883 110460693 110461877
PMAX117329991
MMER123530042 123543601 123543837 123565075
OBI106870165 106874302 106877907
OSN115211659 115217554 115218930
LAK106152698 106173320 106176350
SMMSmp_081450 Smp_166520
OVIT265_02300 T265_05129
EGLEGR_01099
NVE116603438 116604452 5502159 5514401
EPA110231528 110232499 110238136 110241172
ATEN116295465 116299038 116302627 116307456
ADF107332038 107347450
AMIL114957168 114961104 114969551
PDAM113668073 113671460 113682144
SPIS111319244 111327728 111336904 111337240 111337781
DGT114515884 114529099 114531619
XEN124444705 124448475 124452774
HMG100202807 100204155
TADTRIADDRAFT_21256 TRIADDRAFT_32564 TRIADDRAFT_61888
AQU100640578
CSAT104698809
QSU112014063
CMECYME_CMQ456C
GSLGasu_48820
CCPCHC_T00001236001 CHC_T00003677001
EINEint_071220
MBRMONBRDRAFT_28836
SREPTSG_08624
EHIEHI_053610(59.t00033) EHI_103690(348.t00005) EHI_104590(415.t00008) EHI_112890(17.t00006)
EDIEDI_058390 EDI_125320 EDI_305410 EDI_330850
EIVEIN_023510 EIN_097870 EIN_313030 EIN_419280
ACANACA1_277780 ACA1_330420 ACA1_330550
CPVcgd6_1570
CHOChro.60194
TGOTGME49_310810
SMINv1.2.014804.t1(symbB.v1.2.014804.t1) v1.2.033374.t1(symbB.v1.2.033374.t1)
PTIPHATRDRAFT_14301
FCYFRACYDRAFT_177693
TPSTHAPSDRAFT_31247
AAFAURANDRAFT_31875
PIFPITG_20792
PSOJPHYSODRAFT_354969
SPARSPRG_05815 SPRG_15841
EHXEMIHUDRAFT_235054
GTTGUITHDRAFT_161457
TBRTb927.7.1930
TBGTbgDal_VII1920
LMALMJF_15_0030
LIFLINJ_15_0030
LDOLDBPK_150030
LMILMXM_15_0030
LBZLBRM_15_0030
LPANLPMP_150030
NGRNAEGRDRAFT_70056 NAEGRDRAFT_79292
PSTTCH92_09400
IDTC5610_00330
HMIsoil367_13810
ABAWD5400_09450
 » show all
Reference
1  [PMID:14389272]
  Authors
GIBSON DM, AYENGAR P, SANADI DR.
  Title
A phosphatase specific for nucleoside diphosphates.
  Journal
Biochim Biophys Acta 16:536-8 (1955)
DOI:10.1016/0006-3002(55)90275-4
Reference
2
  Authors
Horecker, B.L., Hurwitz, J. and Heppel, L.A.
  Title
The synthesis of ribose 5-pyrophosphate and ribose 5-triphosphate.
  Journal
J Am Chem Soc 79:701-702 (1957)
Reference
3  [PMID:11041856]
  Authors
Yeung G, Mulero JJ, McGowan DW, Bajwa SS, Ford JE
  Title
CD39L2, a gene encoding a human nucleoside diphosphatase, predominantly expressed in the heart.
  Journal
Biochemistry 39:12916-23 (2000)
DOI:10.1021/bi000959z
  Sequence
[hsa:955]
Reference
4  [PMID:12167635]
  Authors
Failer BU, Braun N, Zimmermann H
  Title
Cloning, expression, and functional characterization of a Ca(2+)-dependent endoplasmic reticulum nucleoside diphosphatase.
  Journal
J Biol Chem 277:36978-86 (2002)
DOI:10.1074/jbc.M201656200
  Sequence
[hsa:124583] [rno:246272]
Reference
5  [PMID:15102851]
  Authors
Uccelletti D, O'Callaghan C, Berninsone P, Zemtseva I, Abeijon C, Hirschberg CB
  Title
ire-1-dependent transcriptional up-regulation of a lumenal uridine diphosphatase  from Caenorhabditis elegans.
  Journal
J Biol Chem 279:27390-8 (2004)
DOI:10.1074/jbc.M402624200
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 3.6.1.6
IUBMB Enzyme Nomenclature: 3.6.1.6
ExPASy - ENZYME nomenclature database: 3.6.1.6
BRENDA, the Enzyme Database: 3.6.1.6
CAS: 9027-69-4
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