Entry |
|
Name |
histidine decarboxylase;
L-histidine decarboxylase;
L-histidine carboxy-lyase
|
Class |
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
|
Sysname |
L-histidine carboxy-lyase (histamine-forming)
|
Reaction(IUBMB) |
L-histidine = histamine + CO2 [RN: R01167]
|
Reaction(KEGG) |
|
Substrate |
|
Product |
|
Comment |
The enzyme from animal tissues contains a pyridoxal 5'-phosphate cofactor. The bacterial enzyme contains a tightly-bound pyruvoyl cofactor.
|
History |
EC 4.1.1.22 created 1961
|
Pathway |
ec01110 | Biosynthesis of secondary metabolites |
|
Orthology |
K01590 | histidine decarboxylase |
|
Genes |
PANU: | 101023980 116268502 |
CCAD: | 122443619 122443620 |
MASI: | 127417433 127456382 |
PDAB: | 135739881 135773941 |
HSP: | 118115221 118116306(hdc) |
SSCV: | 125966980 125967121(hdc) |
SASA: | 106587893 106595316 |
OCLA: | 139412274 139412471 139412473 |
PSPA: | 121294326 121298899 |
ARUT: | 117428518 117429746 |
PMRN: | 116939959 116939967 116939973 116941860 116941876 |
LRJ: | 133346349 133346655 133346664 133346669 133346670 |
DSI: | Dsimw501_GD10721(Dsim_GD10721) |
AALB: | 109417567 109417775 |
PPYR: | 116170947 116171023 |
CFEL: | 113376288 113376294 |
BROR: | 134531227 134539649 |
PPOI: | 119089735 119090419 119114033 119114035 |
DPOL: | 127867297 127867298 |
MAEA: | 128221562 128221585 |
REE: | electrica_00039(hdc) |
PSHI: | SAMEA2665130_1235(hdc_1) SAMEA2665130_2542(hdc_2) |
HAEG: | NCTC8502_00552(hdc) |
VNI: | VIBNI_A2877(hdc) VIBNI_A3076 |
VAU: | VANGNB10_67p044(angH) |
VAQ: | FIV01_05665(hdc1) FIV01_17635(hdc2) |
VIB: | VspSTUT11_31370(hdc) |
PIJ: | QEJ31_05820 QEJ31_10230 QEJ31_14785 |
PEP: | AQ505_02510 AQ505_10545 |
PCM: | AY601_1282 AY601_2413 |
PGJ: | QG516_05015 QG516_12775 |
PEDO: | AB3G38_05750 AB3G38_25110 |
SCN: | Solca_2061 Solca_2352 |
SLAS: | L2B55_09735 L2B55_13000 |
OLI: | FKG96_00105 FKG96_21605 |
TOV: | PG911_04825 PG911_12090 |
TPAC: | PG913_03375 PG913_04600 |
TSIG: | D6T69_01230 D6T69_07220 |
FBU: | UJ101_01321(hdc|HDC) |
CGN: | OK18_03110 OK18_08355 |
SSIA: | A7J05_00490 A7J05_36245 |
AGLA: | OIE69_43335 OIE69_44515 |
ASIC: | Q0Z83_012420 Q0Z83_053490 Q0Z83_110290 |
CCAZ: | COUCH_14260 COUCH_14570 |
NLK: | NIES25_38800 NIES25_47400 |
» show all
|
Reference |
|
Authors |
Epps HM |
Title |
Studies on bacterial amino-acid decarboxylases: 4. l(-)-histidine decarboxylase from Cl. welchii Type A. |
Journal |
|
Reference |
|
Authors |
Riley WD, Snell EE. |
Title |
Histidine decarboxylase of Lactobacillus 30a. IV. The presence of covalently bound pyruvate as the prosthetic group. |
Journal |
|
Reference |
|
Authors |
Rosenthaler J, Guirard BM, Chang GW, Snell EE. |
Title |
Purification and properties of histidine decarboxylase from Lactobacillus 30a. |
Journal |
|
Other DBs |
ExplorEnz - The Enzyme Database: | 4.1.1.22 |
ExPASy - ENZYME nomenclature database: | 4.1.1.22 |
|
LinkDB |
|