KEGG   ENZYME: 4.1.1.40
Entry
EC 4.1.1.40                 Enzyme                                 
Name
hydroxypyruvate decarboxylase;
hydroxypyruvate carboxy-lyase
Class
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
Sysname
hydroxypyruvate carboxy-lyase (glycolaldehyde-forming)
Reaction(IUBMB)
hydroxypyruvate = glycolaldehyde + CO2 [RN:R01393]
Reaction(KEGG)
R01393
Substrate
hydroxypyruvate [CPD:C00168]
Product
glycolaldehyde [CPD:C00266];
CO2 [CPD:C00011]
History
EC 4.1.1.40 created 1972
Pathway
ec00630  Glyoxylate and dicarboxylate metabolism
ec01100  Metabolic pathways
Reference
1  [PMID:14186730]
  Authors
HEDRICK JL, SALLACH HJ.
  Title
THE NONOXIDATIVE DECARBOXYLATION OF HYDROXYPYRUVATE IN MAMMALIAN SYSTEMS.
  Journal
Arch Biochem Biophys 105:261-9 (1964)
DOI:10.1016/0003-9861(64)90007-4
Other DBs
ExplorEnz - The Enzyme Database: 4.1.1.40
IUBMB Enzyme Nomenclature: 4.1.1.40
ExPASy - ENZYME nomenclature database: 4.1.1.40
BRENDA, the Enzyme Database: 4.1.1.40
CAS: 37289-43-3
LinkDB

KEGG   REACTION: R01393
Entry
R01393                      Reaction                               
Name
hydroxypyruvate carboxy-lyase (glycolaldehyde-forming)
Definition
Hydroxypyruvate <=> Glycolaldehyde + CO2
Equation
C00168 <=> C00266 + C00011
Reaction class
RC00506  C00168_C00266
Enzyme
4.1.1.40
Pathway
rn00630  Glyoxylate and dicarboxylate metabolism
rn01100  Metabolic pathways
Brite
Enzymatic reactions [BR:br08201]
 4. Lyase reactions
  4.1  Carbon-carbon lyases
   4.1.1  Carboxy-lyases
    4.1.1.40
     R01393  Hydroxypyruvate <=> Glycolaldehyde + CO2
Other DBs
RHEA: 20564
LinkDB

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