Entry
Name
aminocarboxymuconate-semialdehyde decarboxylase;
picolinic acid carboxylase;
picolinic acid decarboxylase;
alpha-amino-beta-carboxymuconate-epsilon-semialdehade decarboxylase;
alpha-amino-beta-carboxymuconate-epsilon-semialdehyde beta-decarboxylase;
2-amino-3-(3-oxoprop-2-enyl)but-2-enedioate carboxy-lyase;
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate carboxy-lyase
Class
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
BRITE hierarchy
Sysname
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate carboxy-lyase (2-aminomuconate-semialdehyde-forming)
Reaction(IUBMB)
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate = 2-aminomuconate semialdehyde + CO2 [RN:
R04323 ]
Reaction(KEGG)
Substrate
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate [CPD:
C04409 ]
Product
Comment
Product rearranges non-enzymically to picolinate.
History
EC 4.1.1.45 created 1972
Pathway
Orthology
K03392 aminocarboxymuconate-semialdehyde decarboxylase
Genes
ETL : 114057691(ACMSD) 114062074
CTIG : 120301244(ACMSD) 120318707
XLA : 108701279(acmsd.L) 733325(acmsd.S)
LPIC : 129274194 129275140
BCOO : 119081911 119085272
PPOI : 119098660 119098678
CEL : CELE_Y71D11A.3(acsd-1)
AOR : AO090005000682 AO090102000067
AFV : AFLA_003494 AFLA_011521
APUU : APUU_30013S APUU_51624S
PPL : POSPLDRAFT_101700 POSPLDRAFT_90129
SCM : SCHCO_02620801(SCHCODRAFT_02620801) SCHCO_02623068(SCHCODRAFT_02623068)
DYG : DYGSA30_21410 DYGSA30_46230
PCQ : PcP3B5_23540 PcP3B5_42190
PTAE : NCTC10697_02305(ditL2)
PHF : NLY38_02355 NLY38_11495
CNC : CNE_2c02880 CNE_2c03490(acmD)
BFN : OI25_251(nbaD) OI25_3889
PHS : C2L64_08155 C2L64_23500
PPAI : E1956_27330 E1956_29310 E1956_31125 E1956_33290 E1956_44120
POLY : PSHI2_03720 PSHI2_10580 PSHI2_13290
POLN : PSHI8_03720 PSHI8_10580 PSHI8_13290
PSPU : NA29_10875 NA29_11835
PNR : AT302_11670 AT302_15060
PFIB : PI93_010940 PI93_021395
PCOM : NTU39_17960 NTU39_18755
PANN : PanNE5_07990 PanNE5_28100
PANX : OYT13_02825 OYT13_16990
BBRO : BAU06_18910 BAU06_20215
BFZ : BAU07_03365 BAU07_04275
BOH : AKI39_05640 AKI39_12270 AKI39_19440
BGV : CAL12_05890 CAL12_13290
PIG : EGT29_10805 EGT29_21385
RHOB : HTY51_01180 HTY51_04200
ABAW : D5400_06990 D5400_20390
BRK : CWS35_25050 CWS35_32125
BGK : IC762_14170 IC762_25295
TRB : HB776_15330 HB776_19340 HB776_21400
XDI : EZH22_15560 EZH22_19725 EZH22_20065
STAR : G3545_04930 G3545_13380 G3545_24895 G3545_26765
AQI : J5J86_15510 J5J86_21635
RHZ : RHPLAN_11170 RHPLAN_14010 RHPLAN_15100 RHPLAN_23120 RHPLAN_36520 RHPLAN_47250 RHPLAN_49490 RHPLAN_49880 RHPLAN_53790 RHPLAN_56290 RHPLAN_60440
JAV : OXU80_15910 OXU80_25015 OXU80_25050
PSIN : CAK95_00835 CAK95_07230 CAK95_10085 CAK95_10615 CAK95_14235 CAK95_28840
TSO : IZ6_03610 IZ6_06830 IZ6_06860
PSTG : E8M01_27225 E8M01_32785
NPN : JI59_12145 JI59_21590
SWI : Swit_1683 Swit_1753 Swit_2308 Swit_2313 Swit_3524
SPHD : HY78_06660 HY78_13960 HY78_13985 HY78_16820 HY78_17170
RDI : CMV14_03935 CMV14_14705 CMV14_18665 CMV14_19440
SPAN : AWL63_14455 AWL63_19795
SPHJ : BSL82_17330 BSL82_17420
SVC : STVA_09570 STVA_12240
AZS : E6C72_20310 E6C72_20385
PAQI : KW060_10600 KW060_10605 KW060_12510
AVM : JQX13_18960 JQX13_43505
MICA : P0L94_00290 P0L94_12715
RUE : DT065_13765 DT065_15160
NDT : L1999_10050 L1999_11880 L1999_17805
ALIC : GI364_08905 GI364_17525
MADI : A7U43_04250 A7U43_14980
MNE : D174_15990 D174_16945
MYN : MyAD_15710 MyAD_16610
MCHT : MCHIJ_22530 MCHIJ_22560
MAUU : NCTC10437_01642 NCTC10437_05531
MTY : MTOK_02140 MTOK_02170 MTOK_02590 MTOK_23910
MANY : MANY_01970 MANY_16640
MMAT : MMAGJ_45550 MMAGJ_48920
MGO : AFA91_00015 AFA91_04735 AFA91_17670
MAUS : JN090_07450 JN090_26225
CEE : CENDO_03475 CENDO_11020
RGO : KYT97_21995 KYT97_24830
SGRF : SGFS_001760 SGFS_030950
SCB : SCAB_15151 SCAB_90581
SHY : SHJG_1753 SHJG_8358 SHJG_8578
SHO : SHJGH_1518 SHJGH_8119 SHJGH_8338
SCX : AS200_01790 AS200_04410
SLE : sle_17510(sle_17510)
SCYA : EJ357_06020 EJ357_36970
SNK : CP967_06845 CP967_29840
SANT : QR300_10305 QR300_41825
SARG : HKX69_01570 HKX69_31290
SCYN : N8I84_00585 N8I84_40205
SLUO : PS467_00395 PS467_38085
SMIB : SMIR_36005 SMIR_36365
SCAJ : O1G22_10660 O1G22_41315
SCAT : P8A18_30315 P8A18_30955
MCAW : F6J84_01050 F6J84_03155
MLZ : F6J85_01805 F6J85_08930
AGY : ATC03_02565 ATC03_10730
ASOI : MTP13_00095 MTP13_01935
LALL : MUN78_00485 MUN78_00880
RAIN : Rai3103_04020 Rai3103_09200
SGRG : L0C25_00105 L0C25_23805
KQI : F1D05_11660 F1D05_36255
KSL : OG809_02115 OG809_28815
KRI : OX958_09390 OX958_20300
ACTW : F7P10_09245 F7P10_16085 F7P10_40045
AGRA : AGRA3207_000776 AGRA3207_002378 AGRA3207_003571
AMAZ : LUW76_05095 LUW76_22710 LUW76_45680 LUW76_47900
ACIR : OG979_20815 OG979_35015 OG979_41940
ACTQ : OG417_15285 OG417_37240
NOA : BKM31_11510 BKM31_47355
NGN : LCN96_28060 LCN96_33585
MHAI : OHB01_02335 OHB01_10085
NML : Namu_1289 Namu_4102 Namu_4901
NAKA : H7F38_10055 H7F38_21925
AMQ : AMETH_1190 AMETH_3754 AMETH_3992
AACD : LWP59_09900 LWP59_19650 LWP59_25355
ARHD : VSH64_04225 VSH64_14645 VSH64_17525 VSH64_30290 VSH64_35335
ACAB : QRX50_14505 QRX50_20880 QRX50_30820
ANW : QP939_33635 QP939_45645
PDX : Psed_1482 Psed_4288 Psed_4983 Psed_5052
PBRO : HOP40_04350 HOP40_21990 HOP40_26725 HOP40_30835
PPEL : H6H00_20670 H6H00_24715
PSDS : K1T35_21530 K1T35_23165
KUT : JJ691_102170 JJ691_14980 JJ691_37160
PMAD : BAY61_11515 BAY61_16770 BAY61_20645
MICH : FJK98_12760 FJK98_12775
MCAY : PVK37_22810 PVK37_22825
PLK : CIK06_17560 CIK06_22390
PFLA : Pflav_004170 Pflav_027490
PSUU : Psuf_003060 Psuf_003680 Psuf_057780 Psuf_082350 Psuf_091820
DACT : KZZ52_26455 KZZ52_45175
NHY : JQS43_06635 JQS43_08615
JTL : M6D93_01810 M6D93_02980
HALG : HUG10_16170 HUG10_18735
» show all
Taxonomy
Reference
Authors
ICHIYAMA A, NAKAMURA S, KAWAI H, HONJO T, NISHIZUKA Y, HAYAISHI O, SENOH S.
Title
STUDIES ON THE METABOLISM OF THE BENZENE RING OF TRYPTOPHAN IN MAMMALIAN TISSUES. II. ENZYMIC FORMATION OF ALPHA-AMINOMUCONIC ACID FROM 3-HYDROXYANTHRANILIC ACID.
Journal
J Biol Chem 240:740-9 (1965)
Other DBs
ExplorEnz - The Enzyme Database: 4.1.1.45
ExPASy - ENZYME nomenclature database: 4.1.1.45
LinkDB
All DBs