KEGG   ENZYME: 4.2.1.129
Entry
EC 4.2.1.129                Enzyme                                 
Name
squalene---hopanol cyclase;
squalene---hopene cyclase (ambiguous)
Class
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
Sysname
hopan-22-ol hydro-lyase
Reaction(IUBMB)
hopan-22-ol = squalene + H2O [RN:R07323]
Reaction(KEGG)
R07323
Substrate
hopan-22-ol [CPD:C06309]
Product
squalene [CPD:C00751];
H2O [CPD:C00001]
Comment
The enzyme produces the cyclization products hopene (cf. EC 5.4.99.17) and hopanol from squalene at a constant ratio of 5:1.
History
EC 4.2.1.129 created 2011
Pathway
ec00909  Sesquiterpenoid and triterpenoid biosynthesis
ec01110  Biosynthesis of secondary metabolites
Orthology
K06045  squalene-hopene/tetraprenyl-beta-curcumene cyclase
Genes
MGR: MGG_00792
PPEI: PpBr36_08342
PGRI: PgNI_08500 PgNI_09483
FOX: FOXG_17453
PLJ: 28892859(PLICBS_009024)
PTKZ: JDV02_008633
CHIG: CH63R_11561
CDET: 87942346(CDEST_05843) 87946309(CDEST_09807)
PFY: PFICI_08232
PSCO: LY89DRAFT_588691
AFM: AFUA_5G00110 AFUA_7G00260 AFUA_7G00300
ACT: ACLA_024280
NFI: NFIA_112770 NFIA_112850
AOR: AO090038000098
ANG: An01g01290
AFV: AFLA_012369
ALUC: AKAW2_30529A
ACHE: ACHE_80355A
PCS: N7525_003977
AJE: HCAG_06936
ADL: AURDEDRAFT_54410
FAU: Fraau_0755 Fraau_3212
DJA: HY57_12650
DYE: EO087_12870(shc)
DCS: ISN74_17650(shc)
DTL: H8F01_19305(shc)
DTA: DYST_00503
PFUV: NLK61_04510
AVN: Avin_20760
AVL: AvCA_20760
AVD: AvCA6_20760
TTU: TERTU_3240(shc)
ASIP: AQUSIP_21910(shc)
LFA: LFA_3651(shc)
MCA: MCA0812(sqhC)
METU: GNH96_04640(shc)
MMEO: OOT43_06745(shc)
MEEF: JWZ97_02685(shc) JWZ97_06755(shc) JWZ97_18265(shc)
MMT: Metme_2461 Metme_3474
MDN: JT25_015465 JT25_019085
MDH: AYM39_06140
MKO: MKLM6_1250 MKLM6_1920
METL: U737_05050(shc)
MPAD: KEF85_15850(shc)
MELL: IVG45_06140(shc) IVG45_22120(shc)
MRP: NM686_004035(shc)
MMOT: QZJ86_06480(shc) QZJ86_09080(shc)
MEEP: JWZ98_04660(shc)
MEEC: PL263_09030(shc)
MEUP: QC632_07170(shc) QC632_10780(shc)
MAH: MEALZ_2523(shc) MEALZ_3097(shc)
MBUR: EQU24_14525(shc) EQU24_15370(shc)
MPSY: CEK71_04645(shc) CEK71_11190(shc)
MMAI: sS8_2362
MSZE: MSZNOR_4074(shc)
MMOB: F6R98_20825(shc)
MEIN: methR_P0253
MOZ: MoryE10_13350(shc)
MISZ: MishRS11D_16130(shc)
MESL: KKZ03_12960(shc)
MECH: Q9L42_016190(shc)
MLAU: ACEPPP_03405(shc) ACEPPP_03880(shc)
MEIY: MIN45_P1532
MCAU: MIT9_P1119
NOC: Noc_1320
NHL: Nhal_1309
NWA: Nwat_1202
NWR: E3U44_16810(shc)
NTT: TAO_1298
NTG: NSCAC_0561(shc)
AFY: BW247_04720
ACII: C4901_05415(shc)
ATY: A9R16_011075(shc)
SALN: SALB1_2148
RPJ: N234_32520
REH: H16_B2207(sqhC)
CNC: CNE_2c21850(shc)
CUH: BJN34_33525
REU: Reut_B4954
RME: Rmet_4148(sqhC) Rmet_4403(shc)
CTI: RALTA_B1983(shc)
CBW: RR42_s1630 RR42_s2399
CGD: CR3_3463(shc)
CCUP: BKK81_10785 BKK81_26340
CUP: BKK80_11040 BKK80_29975
CUU: BKK79_01795 BKK79_20625
CPAU: EHF44_18565(shc) EHF44_19255(shc)
COX: E0W60_04545(shc)
CCAM: M5D45_21255(shc)
CCAX: KZ686_17095(shc)
CUK: KB879_16310(shc)
CNAN: A2G96_29215
CUPR: IC580_17990(shc)
CUPE: KLP38_19720(shc)
CUPP: CTP10_R56040(shc)
BMA: BMAA2100(shc)
BMV: BMASAVP1_1129(shc)
BML: BMA10229_1408(shc)
BMN: BMA10247_A2394(shc)
BMAZ: BM44_3673(shc)
BMAL: DM55_3714(shc)
BMAE: DM78_4588(shc)
BMAQ: DM76_4409(shc)
BMAI: DM57_14635
BMAF: DM51_3764(shc)
BMAB: BM45_4450(shc)
BPS: BPSS2339(shc)
BPM: BURPS1710b_A1490(shc)
BPL: BURPS1106A_A3161(shc)
BPD: BURPS668_A3275(shc)
BPSE: BDL_5818(shc)
BPSM: BBQ_3760(shc)
BPSU: BBN_5840(shc)
BPSD: BBX_4987(shc)
BPZ: BP1026B_II2520(shc)
BPQ: BPC006_II3107
BPK: BBK_5125(shc)
BPSH: DR55_5386(shc)
BPSA: BBU_3646(shc)
BPSO: X996_5156(shc)
BUT: X994_4705(shc)
BTE: BTH_II2359(shc)
BTQ: BTQ_3274(shc)
BTJ: BTJ_4306(shc)
BTZ: BTL_5108(shc)
BTD: BTI_4772(shc)
BTV: BTHA_5108(shc)
BTHE: BTN_4769(shc)
BTHM: BTRA_5036(shc)
BTHA: DR62_4873
BTHL: BG87_5103(shc)
BOK: DM82_3978(shc)
BOC: BG90_4049(shc)
BUU: WS70_28725
BSAV: WS86_18650
BHG: I6G56_29175(shc)
BUD: AQ610_31635
BVI: Bcep1808_3808
BVE: AK36_4901(shc)
BUR: Bcep18194_B0019 Bcep18194_C7519
BCM: Bcenmc03_4556 Bcenmc03_6546
BCH: Bcen2424_5679 Bcen2424_6062
BCJ: BCAM2831(shc) BCAS0167(shc)
BCEN: DM39_5013(shc) DM39_6527(shc)
BCEW: DM40_3396(shc)
BCEO: I35_6711(shc) I35_7176(shc)
BAM: Bamb_4951 Bamb_6104
BAC: BamMC406_5504 BamMC406_5865
BMJ: BMULJ_05349(shc) BMULJ_05535(sqhC)
BMU: Bmul_3175 Bmul_5992
BMK: DM80_4553(shc) DM80_6441(shc)
BMUL: NP80_3379(shc)
BCT: GEM_5581
BCED: DM42_5157(shc) DM42_6654(shc)
BCEP: APZ15_24775 APZ15_33895
BDL: AK34_4974(shc)
BPYR: ABD05_21485 ABD05_34000
BCON: NL30_18005 NL30_34350
BUB: BW23_4001(shc) BW23_5528(shc)
BDF: WI26_26715 WI26_29610
BLAT: WK25_29560
BTEI: WS51_10745 WS51_29420
BSEM: WJ12_19620 WJ12_34020
BPSL: WS57_00085 WS57_17555
BMEC: WJ16_19345 WJ16_32495
BSTG: WT74_28725 WT74_32860
BSTL: BBJ41_27930 BBJ41_33625
BANN: JFN94_18175(shc)
BARI: NLX30_22955(shc) NLX30_35610(shc)
BAEN: L3V59_29250(shc) L3V59_39335(shc)
BSER: R0290_20615(shc) R0290_30685(shc)
BGL: bglu_2g02870 bglu_2g22720
BGU: KS03_3364(shc) KS03_3646(shc)
BUG: BC1001_4759
BGF: BC1003_4523
BGD: bgla_2g03260 bgla_2g29870
BGO: BM43_6721(shc) BM43_7081(shc)
BYI: BYI23_B013720
BUK: MYA_3465
BUL: BW21_4301(shc)
BUQ: AC233_26250
BGP: BGL_2c02630 BGL_2c29490
BPLA: bpln_2g03050 bpln_2g29530
BUM: AXG89_19290
BUI: AX768_29055
BURK: DM992_25920(shc) DM992_34725(shc)
BURT: BTHE68_39720(shc)
BURM: GJG85_25390(shc) GJG85_31190(shc)
BXE: Bxe_B0012
BXB: DR64_5376(shc)
BPH: Bphy_4137
BGE: BC1002_5086
BPX: BUPH_01324
BPY: Bphyt_7029
BUZ: AYM40_35475
BFN: OI25_5474(shc)
BCAI: K788_0000709
PSPW: BJG93_21555(shc)
PARA: BTO02_22395
PARB: CJU94_28535(shc)
PHS: C2L64_18375(shc)
PTER: C2L65_16210(shc)
PGP: CUJ91_29990(shc)
PCJ: CUJ87_28080(shc)
PTS: CUJ90_23645(shc)
PCAF: DSC91_003033
PMEG: FNZ07_04850(shc)
PTRO: G5S35_20780(shc) G5S35_32265(shc)
PGIS: I6I06_28030(shc)
PACP: FAZ97_21335(shc) FAZ97_23545(shc)
PACS: FAZ98_17480(shc) FAZ98_18980(shc)
PEW: KZJ38_24040(shc)
PDIO: PDMSB3_3365.1(shc)
PBRY: NDK50_21370(shc)
PSAA: QEN71_16430(shc)
PKF: RW095_15080(shc)
PBON: QS306_13715(shc)
PPAI: E1956_24900(shc) E1956_40200(shc)
PHUN: U0042_03530(shc)
PLAD: PPGU16_48740(shc)
PAZZ: PBP221_33220(shc)
BRH: RBRH_03441
PPNO: DA70_09090
PPNM: LV28_21715
PRB: X636_17400
PPUL: RO07_16105
PSPU: NA29_21045
PAPI: SG18_24805
PVE: UC34_07360
POX: MB84_11695
PTX: ABW99_02790
PFG: AB870_18055
PNR: AT302_26700
PAND: DRB87_06625(shc)
PFIB: PI93_020480(shc)
PCOM: NTU39_08370(shc)
PANN: PanNE5_00610(shc)
PANX: OYT13_06625(shc)
CABA: SBC2_70700(shc)
BUO: BRPE64_BCDS00810
CABK: NK8_42280(shc)
BUE: BRPE67_BCDS00680
VCV: GJV44_p00024
TVL: FAZ95_23935(shc)
TCAR: U0034_25740(shc)
MFY: HH212_18840(shc)
MLIR: LPB04_14425(shc)
TMJ: P0M04_22840(shc)
BBAG: E1O_05330
NEU: NE1168
NET: Neut_1507
NIT: NAL212_0906
NII: Nit79A3_1066
NCO: AAW31_03760
NUR: ATY38_01960
NST: Nstercoris_01634
NMU: Nmul_A2556
NLC: EBAPG3_003585(shc)
NIZ: NNRS527_00243
PMOB: HG718_04905(shc)
KMN: HW532_17945(shc)
PECT: BN1012_Phect101
RHI: NGR_a00460(shc)
SINO: SS05631_a45190
ESJ: SJ05684_a40290
EAW: ACEP9W_28675(shc)
BJA: blr3004(shc)
BJU: BJ6T_67630
BJP: RN69_32800
BRA: BRADO6252(shc)
BBT: BBta_1355(shc)
BRS: S23_49930(shc)
AOL: S58_64230
BRC: BCCGELA001_13475
BRAD: BF49_1688
BIC: LMTR13_28330
BRO: BRAD285_6198(shc)
BRK: CWS35_18225(shc)
BOT: CIT37_38575(shc)
BRQ: CIT40_09520(shc)
BGQ: X265_25980(shc)
BGZ: XH91_24120(shc)
BSYM: CIT39_08640(shc)
BBET: F8237_05025(shc)
BARH: WN72_16450(shc)
BVZ: BRAD3257_5706(shc)
BEL: BE61_70440(shc)
BDG: LPJ38_18020(shc)
BSEP: HAP48_0030900(shc)
BQB: J4P68_0032160(shc)
BSEI: KMZ68_09720(shc)
BBAN: J4G43_017135(shc)
BCAN: BcanWSM471_14295(shc)
BAUT: QA635_28520(shc)
BBRA: QA636_30410(shc)
BGK: IC762_11730(shc)
BCOU: IC761_24415(shc)
BPAH: QA639_15470(shc)
BXN: I3J27_11375(shc)
BROS: QUH67_11930(shc)
BRAZ: LRP30_12840(shc)
BOY: LQG66_29845(shc)
BRAY: ML401_10330(shc)
RPA: TX73_019370(shc)
RPB: RPB_1726
RPC: RPC_1720
RPD: RPD_3573
RPE: RPE_4468
RPT: Rpal_4261
RPX: Rpdx1_1605
RBK: E0H22_09840(shc)
RHOR: ONR75_22870(shc)
RHOL: RBJ75_00980(shc)
NWI: Nwi_2269
NHA: Nham_2682
OCA: OCAR_6671(shc)
OCG: OCA5_c13970(shc)
OCO: OCA4_c13970(shc)
PCAX: AFIC_002153(shc)
VGO: GJW-30_1_02142(shc)
TRB: HB776_13755(shc)
TALZ: RPMA_20050(shc)
TARD: RSO67_07450(shc)
STAR: G3545_15480(shc)
PTAW: DW352_21885(shc)
MEA: Mex_1p1818(shc)
MDI: METDI2705(shc)
MEX: Mext_1944
MCH: Mchl_2220 Mchl_5491
MPO: Mpop_1835
MZA: B2G69_17180
METQ: MSPGM_19230(shc)
MRD: Mrad2831_5426
MET: M446_6347
MNO: Mnod_7146
MOR: MOC_3575(shc) MOC_6001
META: Y590_09040
MAQU: Maq22A_c25255(sqhC)
MPHY: MCBMB27_04727 MCBMB27_05561
MEE: DA075_06145(shc)
METD: C0214_10795(shc)
METX: A3862_03545 A3862_04290
METS: DK389_19255(shc)
METI: DK427_24635(shc)
MMES: MMSR116_24425(shc)
MTEA: DK419_24980(shc)
MIND: mvi_34500(shc_1) mvi_55610(shc_2)
MOG: MMB17_13750(shc)
MTAD: M6G65_20525(shc)
MECL: CLZ_08600(shc) CLZ_16165(shc)
MFUJ: ABC766_12290(shc)
MENI: GU700_08600(shc) GU700_16170(shc)
MENS: LOK46_28395(shc)
BID: Bind_3156
MSL: Msil_3243
MTUN: MTUNDRAET4_2106
MLG: CWB41_01845(shc)
MEDK: QEV83_07965(shc)
BBAR: RHAL1_00135(shc)
BBAI: CU048_11335(shc)
HDN: Hden_0477
HDT: HYPDE_24888
HMC: HYPMC_3771(shc)
RVA: Rvan_3017
RLAC: QMO75_10895(shc)
RHZ: RHPLAN_23310
MSC: BN69_1707
MROS: EHO51_00730(shc)
MHEY: H2LOC_015870(shc)
MPAR: F7D14_11010(shc)
MIWA: SS37A_09770(shc)
MESZ: LNB28_07245(shc)
MTW: CQW49_17110(shc)
MECQ: MSC49_00950(shc)
PSIN: CAK95_04485
TSO: IZ6_27190(shc)
RBM: TEF_04810
LIZ: LGH83_05690(shc) LGH83_16590(shc)
CAUL: KCG34_08815(shc)
ZMO: ZMO0872 ZMO1548
ZMN: Za10_0420 Za10_1658
ZMM: Zmob_0425 Zmob_1582
ZMB: ZZ6_0423 ZZ6_1551
ZMI: ZCP4_0439 ZCP4_1608
ZMC: A265_00434 A265_01607
ZMR: A254_00434 A254_01607
ZMP: Zymop_0393
NOR: FA702_05035(shc)
NHUM: PQ457_14470(shc)
SPHM: G432_09180
SPAN: AWL63_21320
SPHA: D3Y57_13895(shc)
SMOR: LHA26_10020(shc)
SNOS: K8P63_14010(shc)
SABI: PBT88_02345(shc)
SAAP: E2E30_11400(shc)
POQ: KZX46_17575(shc)
PMEA: KTC28_15765(shc)
GOX: GOX2260
GOH: B932_1860 B932_2742
GOY: GLS_c24030
GAL: A0U94_06170
GTI: FXF46_02260(shc) FXF46_13825(shc)
GSP: IGS75_12765(shc)
GFA: MKW11_02670(shc) MKW11_14255(shc)
GBE: GbCGDNIH1_2107
GBH: GbCGDNIH2_2107
GBC: GbCGDNIH3_2107
GBS: GbCGDNIH4_2107
GDI: GDI1620
GDJ: Gdia_1825
GXY: GLX_03980
GXL: H845_2357
KNA: B0W47_03475
KEU: S101446_01652 S101446_02249
KSC: CD178_01159(shc)
KRE: GWK63_07055(shc)
KOI: LV478_02470(shc) LV478_05305(shc)
APT: APA01_01950 APA01_13100
APW: APA42C_01950 APA42C_13100
APF: APA03_01950 APA03_13100
APU: APA07_01950 APA07_13100
APG: APA12_01950 APA12_13100
APQ: APA22_01950 APA22_13100
APX: APA26_01950 APA26_13100
APZ: APA32_01950 APA32_13100
APK: APA386B_146(shc) APA386B_1683(shc)
ASZ: ASN_2208(shc)
ASV: WG31_01015 WG31_07060
AACE: A0U92_11670
APER: A0U91_06975
APOM: CPF11_00890(shc) CPF11_06325(shc)
ATO: CIW82_01590(shc)
AASC: A4S02_04580 A4S02_11565
ACET: DS739_01115(shc) DS739_06780(shc)
AOT: AcetOri_orf02407
AOY: EOV40_001040(shc) EOV40_006100(shc)
ACEK: FLP30_07000(shc)
ABG: Asbog_02594
KBA: A0U89_01840
NCH: A0U93_11945
COQ: D9V35_08220(shc)
COMM: GN303_08020(shc)
NTN: D5366_10600(shc)
NEH: E3E11_07665(shc)
SSAM: E3D00_09665(shc)
SWF: E3E12_06930(shc)
BOB: GN304_03820(shc)
BOMB: GT348_03345(shc)
EBLA: JGUZn3_04090(shc)
LCK: HN018_00140(shc)
KHA: IFJ82_01385(shc) IFJ82_02850(shc)
PARZ: DTQ13_08075(shc)
RAP: RHOA_2339(shc)
KDP: N5W20_09470(shc)
NGU: QN315_11435(shc)
ACR: Acry_1685
AMV: ACMV_17290(shc)
RGI: RGI145_09730
ROS: CTJ15_07690(shc)
RMUC: FOB66_09715(shc)
RMT: IAI58_18595(shc)
SRF: LHU95_12750(shc)
SHUM: STHU_32380(shc)
SVC: STVA_26800(shc)
ABS: AZOBR_p150003(shc)
ABQ: ABAZ39_20220
ABF: AMK58_14585
AZT: TSH58p_24395(shc)
AARE: D3093_22270(shc)
AZP: E6C67_16100(shc)
NAO: Y958_22670(shc)
SKT: IGS68_20550(shc)
SMUC: JL100_005555(shc)
SROE: JL101_005465(shc)
RRU: Rru_A0062
RRF: F11_00315
RPM: RSPPHO_00431
MAGX: XM1_1990(shc)
MAGN: WV31_17685
DEX: HWD60_12235(shc)
DVN: HQ394_07730(shc)
AALU: ABWI00_08800(shc)
MAG: amb1367
HTQ: FRZ44_04170
HADH: FRZ61_04440
MAGQ: MGMAQ_1494(shc)
HFL: PUV54_16320(shc)
HFO: ABFZ83_06020(shc)
AFR: AFE_2124(shc)
AFE: Lferr_1783
ACU: Atc_2240
ACZ: Acaty_c2080
AFI: Acife_1270
AFJ: AFERRID_02580
ATX: GCD22_00868(shc)
AFP: K1Y48_00780(shc)
ACIY: MQE22_03705(shc)
GSU: GSU0688(shc-1) GSU3061(shc-2)
GSK: KN400_0662(shc-1) KN400_3000(shc-2)
GME: Gmet_0419(shc-2) Gmet_2820(shc-1)
GPI: GPICK_04085
GAO: A2G06_14395
GBZ: JZM60_01925(shc) JZM60_07780(shc)
GEM: GM21_0885 GM21_2435
GEB: GM18_3439
GEF: FO488_03610(shc)
GEV: GSVR_11110(shc-2) GSVR_16500(shc-1)
GEC: GEO60473_01410(shc_1) GEO60473_24790(shc_2)
GUR: Gura_1020
GEO: Geob_3234(shc-2) Geob_3662(shc-1)
GLO: Glov_2233
TAMM: GEAMG1_0845(shc) GEAMG1_2732(shc)
GBM: Gbem_1815 Gbem_3360(shc)
GBN: GEOBRER4_08490(shc-1)
GER: KP004_03725(shc)
GSUB: KP001_11685(shc)
GNT: KP003_03545(shc)
GPL: M1B72_17015(shc)
PCA: Pcar_0355(shc-1) Pcar_0441(shc-2)
PACE: A6070_01815
PPD: Ppro_0765 Ppro_1189
DSA: Desal_1353
DHY: DESAM_22870(shc)
DAF: Desaf_0189
DAL: Dalk_0344
DAO: Desac_0410
SFU: Sfum_1989 Sfum_2736
AFW: Anae109_4079
AORY: AMOR_12190(shc)
APAU: AMPC_20760(shc)
AGE: AA314_01781 AA314_05090 AA314_06818
CFUS: CYFUS_004654
CCRO: CMC5_070180
PAUU: E8A73_035210
MRM: A7982_05934 A7982_06057
STI: Sthe_2007
RUFI: K0V07_00965(shc)
PUO: RZN69_15260(shc)
MTAR: DF168_00501(shc)
AMU: Amuc_0525
ROO: G5S37_27275
VEG: SAMN05444156_1461
FPES: NXS98_09905(shc)
MIN: Minf_0399(sqhC)
MKC: kam1_559
MFH: MFUM_0665(sqhC)
MCAO: IT6_08020(shc)
MEAP: MTHMO_0319(sqhC)
RBA: RB2901 RB2998 RB5934(shc)
RHOI: PSR62_11920
PSL: Psta_0174 Psta_0945 Psta_1738
PIR: VN12_10680
RUL: UC8_30240 UC8_37370 UC8_42670(sqhC)
RML: FF011L_18080(sqhC) FF011L_23770 FF011L_27960
MFF: MFFC18_41350(sqhC) MFFC18_46730
ROL: CA51_14560 CA51_39620 CA51_52070(shc)
RUV: EC9_51680(shc)
RCF: Poly24_51710(shc)
AHEL: Q31a_22040(shc_1) Q31a_45820 Q31a_46410(shc_2)
LCRE: Pla8534_14350 Pla8534_20930(sqhC) Pla8534_22350(shc)
AAGG: ETAA8_10120 ETAA8_62290(shc_1) ETAA8_62430(shc_2)
BVO: Pan97_09230(shc_1) Pan97_09420(shc_2)
BREM: PSR63_06100 PSR63_06195
RLC: K227x_13510 K227x_22910(shc) K227x_40600
SMAM: Mal15_09590(shc)
SNEP: Enr13x_63140(shc)
SMAE: TBK1r_65880(shc)
TTF: THTE_1935 THTE_2306 THTE_3916
AMUC: Pan181_46940
PND: Pla175_18410(shc)
AMOB: HG15A2_00430 HG15A2_44900(shc)
BGOK: Pr1d_23410(shc)
PLM: Plim_0903 Plim_1904 Plim_4048
PEH: Spb1_06060 Spb1_15260(shc_1) Spb1_27280(shc_2)
PBS: Plabr_0011 Plabr_2149 Plabr_2180
PLS: VT03_01505 VT03_09805 VT03_26490(shc_2) VT03_32785(shc_3)
PLH: VT85_07400 VT85_20580(shc)
FMR: Fuma_03128(shc) Fuma_03348 Fuma_03645
GMR: GmarT_24340(shc_1) GmarT_47090(shc_2) GmarT_54430
GIM: F1728_02355 F1728_17190 F1728_21675
GPN: Pan110_23630(shc_1) Pan110_45560(shc_2)
GFM: Enr17x_25490(shc_2) Enr17x_47510(shc_3)
GAZ: Pan241w_24790(shc_2) Pan241w_46480(shc_3)
GAW: V144x_15110(shc_1) V144x_34540(shc_2)
GAX: Pan161_10520(shc_1) Pan161_47550(shc_2)
MRI: Mal4_31980(shc) Mal4_50450(sqhC)
SDYN: Mal52_02110 Mal52_19580(shc) Mal52_49180(sqhC)
PLON: Pla110_32440(shc_1) Pla110_36000(shc_2)
ACAF: CA12_21620(shc_1) CA12_23420(shc_2)
SVP: Pan189_23750(shc)
TPOL: Mal48_30440(sqhC) Mal48_49250(shc)
CHYA: V22_12590(shc_1) V22_22080(shc_2)
CCOS: Pan44_30420(shc_1) Pan44_41330(shc_2)
PVAR: SH412_001918 SH412_002047
CCOP: Mal65_29790(sqhC)
SCHL: QJS52_19910 QJS52_23945
GES: VT84_13505(shc_1) VT84_20280(shc_2) VT84_26700 VT84_29250 VT84_38410
GOG: C1280_00600 C1280_05755 C1280_11220 C1280_15490 C1280_24955
GMS: SOIL9_23180 SOIL9_23870
TIM: GMBLW1_02660 GMBLW1_14470 GMBLW1_45200
LRS: PX52LOC_02174(shc) PX52LOC_03438
FTJ: FTUN_0199 FTUN_6577 FTUN_6629
ULI: ETAA1_06450(sqhC) ETAA1_31320(shc)
TSPH: KIH39_00860
IPA: Isop_2195 Isop_2285
SACI: Sinac_2971 Sinac_7098 Sinac_7166
PBOR: BSF38_01778 BSF38_02668 BSF38_04488(shc)
AGV: OJF2_06420 OJF2_33050 OJF2_48380(shc)
TPLA: ElP_21670(shc)
KST: KSMBR1_2174
BROC: IPI25_11045(shc)
BPIT: BPIT_03260
JET: L3J17_11495(shc)
PHM: PSMK_10120
PCOR: KS4_02460(shc)
MCAD: Pan265_12120(shc)
HBS: IPV69_04890(shc) IPV69_19905
UAM: UABAM_04164 UABAM_06659
UHL: UABHE_002932(shc)
ABA: Acid345_1740
ACA: ACP_3329(shc)
ACM: AciX9_1592
GMA: AciX8_1346
GRW: FTO74_09370(shc)
GRB: GOB94_00715(shc)
TSA: AciPR4_1994
TRS: Terro_1976 Terro_2342
TALB: FTW19_15285(shc) FTW19_25255(shc)
ABAS: ACPOL_1272
EDA: GWR55_04250(shc)
EDG: H7846_10385(shc) H7846_17710(shc)
EPL: P4G45_07365(shc)
ADIN: H7849_03035(shc) H7849_09985
ORP: MOP44_14955(shc)
TGI: RBB81_16055(shc)
TEMP: RBB75_17625(shc)
TPSC: RBB77_13660(shc)
CTM: Cabther_B0033
CVL: J8C06_11290(shc)
CHLO: J8C02_11955(shc)
SUS: Acid_1186 Acid_1260 Acid_3957
PFER: IRI77_14385(shc) IRI77_19010(shc) IRI77_21610
ABAC: LuPra_04105
SCOR: J3U87_05010 J3U87_08330
GBA: J421_6268
ANF: AQPE_3419
MBAS: ALGA_3836
FSD: LXD69_15565
MARE: EJ994_14175
NDE: NIDE0861(shc)
NMV: NITMOv2_0719(shc)
NIO: NITINOP_1569(shc)
NJA: NSJP_1836(shc)
NKF: Nkreftii_003246
NIF: W02_30620(shc)
NTI: DNFV4_01141
NALL: PP769_06180(shc) PP769_12205(shc)
NNEO: PQG83_03055(shc) PQG83_17410(shc)
LFC: LFE_1762
LFI: LFML04_0857
LFP: Y981_03765
LEG: ABH19_09330
NLI: G3M70_08320(shc)
NWT: NSPWAT_2830(shc)
NVA: G3M78_00185(shc)
BBAE: FRD01_14570
AAC: Aaci_2443
AAD: TC41_2733(shc)
AACO: K1I37_18755(shc)
AFAS: NZD89_04670(shc)
RHER: EHE19_016535
EUU: ADJ67_00305
NNO: NONO_c55610
NTP: CRH09_14130 CRH09_23905(shc) CRH09_26605
NAH: F5544_21420
NWL: NWFMUON74_15100
NHU: H0264_16265
SCO: SCO6764(SC6A5.13)
SALB: XNR_0267
SMA: SAVERM_1650(hopA)
SGR: SGR_962(hopA)
SGB: WQO_30780
SFI: SFUL_6533
SANL: KZO11_32870(shc)
SGRF: SGFS_026660
SCYE: R2B67_03315(shc)
SCB: SCAB_12951(hopA)
SSX: SACTE_5926
SVL: Strvi_2867 Strvi_5132
SHY: SHJG_7654
SHO: SHJGH_7415
SRC: M271_11170
SMAL: SMALA_0221 SMALA_6345
SSOI: I1A49_35575(shc)
SFA: Sfla_0644
SBH: SBI_00220 SBI_02586(hopA)
SVE: SVEN_6451
SDV: BN159_1597(shc)
SALS: SLNWT_6814
STRP: F750_6225
SCI: B446_30850
SLV: SLIV_04695(shc)
SGU: SGLAU_28290
SVT: SVTN_31635
STRE: GZL_01982
SCW: TU94_29090
SLD: T261_1203
SLC: SL103_23610
SXI: SXIM_51340
STRM: M444_28180
STRC: AA958_32215
SAMB: SAM23877_6414(shc)
SPRI: SPRI_0982
SCZ: ABE83_03660 ABE83_33310
SCX: AS200_08990 AS200_35430
SRW: TUE45_00448 TUE45_07304(shc)
STRF: ASR50_30475
SLE: sle_10520(sle_10520)
SRN: A4G23_05042(shc)
SPAV: Spa2297_28170
STRT: A8713_27345 A8713_30300
SCLF: BB341_00560 BB341_02805
SGS: AVL59_15150
STSI: A4E84_34770
SKY: D0C37_02860(shc)
SALW: CP975_31255(shc)
SGM: GCM10017557_11400
SCAD: DN051_08510(shc)
SPHW: NFX46_12680(shc)
SGRS: V9K83_04595(shc) V9K83_32575
SLS: SLINC_6334 SLINC_7200
SNR: SNOUR_08855
SALU: DC74_6782 DC74_7525
SALL: SAZ_35230 SAZ_38855
SPLU: LK06_028610
STRD: NI25_04620
SNW: BBN63_05555
SAUO: BV401_04845 BV401_35705
SSIA: A7J05_05110
SVU: B1H20_31600
SPUN: BFF78_06420
SGV: B1H19_34415 B1H19_35795
SLAU: SLA_6410
SALF: SMD44_07318(shc)
SALJ: SMD11_1098(shc)
SLX: SLAV_07390(shc)
STRO: STRMOE7_31880
SFK: KY5_7137
SNZ: DC008_29665(shc)
SGE: DWG14_01401(shc)
SRJ: SRO_1200
SLK: SLUN_34175(shc)
SDX: C4B68_04810(shc)
SGD: ELQ87_05325(shc)
SQZ: FQU76_00220 FQU76_29310(shc) FQU76_33520
SCYA: EJ357_40565(shc)
SAST: CD934_03265(shc)
SNQ: CP978_28955(shc)
STIR: DDW44_27260(shc)
SKA: CP970_04385(shc)
SGZ: C0216_10745(shc)
SVN: CP980_05860(shc)
SNK: CP967_02225(shc)
SRK: FGW37_27085(shc) FGW37_31230 FGW37_32255
SFIC: EIZ62_04350(shc)
SGAL: CP966_00565 CP966_31125(shc)
SSPO: DDQ41_28530(shc)
SVR: CP971_05135(shc)
SPAD: DVK44_19855 DVK44_30855(shc)
SFY: GFH48_08095(shc)
SAQU: EJC51_39490(shc)
SGF: HEP81_01168(shc)
SCAV: CVT27_30035(shc)
SSEO: D0Z67_24820(shc)
SBY: H7H31_30105(shc)
SRIM: CP984_05710(shc) CP984_38180(shc)
SSUB: CP968_06340(shc)
SPHV: F9278_40805(shc)
SCIN: CP977_10960 CP977_28910(shc)
SFUG: CNQ36_31010(shc)
SPAC: B1H29_05430
STSU: B7R87_29445
SCHA: CP983_06415(shc)
SGX: H4W23_32745(shc)
SCOE: CP976_37120(shc)
SBAT: G4Z16_03480(shc)
SSPB: CP982_34195(shc)
SNF: JYK04_06893(shc)
SPLA: CP981_01965 CP981_32445(shc)
SBRO: GQF42_07575 GQF42_37630(shc)
STUI: GCM10017668_61190
SATA: C5746_35860(shc)
SCHF: IPT68_31720(shc)
SHUN: DWB77_01404(shc)
SHAR: HUT13_25935
SCYG: S1361_33295(shc)
SFEU: IM697_28460(shc)
SLIA: HA039_04290(shc)
SDW: K7C20_01965 K7C20_30995(shc)
SVD: CP969_32315(shc)
SCAL: I6J39_31405(shc)
SAUH: SU9_029415(shc)
SFB: CP974_26940(shc)
SMOB: J7W19_27235(shc) J7W19_27655
SPEU: CGZ69_31900(shc)
SROI: IAG44_38275
SXN: IAG42_05315(shc)
SGJ: IAG43_28430(shc)
SHK: J2N69_32850(shc)
SANU: K7396_06215(shc)
STRY: EQG64_31380(shc)
SACT: DMT42_32475(shc)
SMAO: CAG99_06465 CAG99_26915
SGOB: test1122_24235(shc)
SINE: KI385_36760(shc)
SLF: JEQ17_08695(shc)
SDEC: L3078_39030(shc)
SAOV: G3H79_04595(shc)
SDUR: M4V62_07610(shc)
SYAN: NRK68_28735(shc)
SRUG: F0345_25815(shc)
SAKB: K1J60_05310(shc)
STAA: LDH80_07695(shc) LDH80_27015
SNIG: HEK616_45640
SVIO: HWN34_02290(shc)
SCAE: IHE65_05700(shc)
STUB: MMF93_28865(shc)
SSPN: LXH13_33345(shc)
SCIR: STRCI_006886(shc)
SXT: KPP03845_106143(shc)
SLON: LGI35_35510(shc)
SDRZ: NEH16_03340(shc)
STUD: STRTU_001022(shc)
STEE: F3L20_15030(shc)
SENG: OJ254_27400(shc)
SGK: PET44_26710(shc)
SANT: QR300_09450(shc) QR300_39875
SYUN: MOV08_08750(shc)
SARG: HKX69_04515(shc)
SJN: RI060_05745(shc)
SCYN: N8I84_34265(shc)
SOV: QZH56_04775(shc)
SFIY: F0344_02690(shc)
SHAU: K9S39_07915(shc)
SKG: KJK29_04185(shc)
SCOA: QU709_04620(shc)
SLAI: P8A22_04075(shc)
SROC: RGF97_03575(shc)
SFP: QUY26_05730(shc)
SCHG: NRO40_25440(shc)
STTN: BSL84_28465
SINN: ABB07_04935
STRZ: OYE22_29485(shc)
SCAY: PYS65_03840(shc)
KBU: Q4V64_00240 Q4V64_47120(shc)
SARM: DVA86_08025(shc)
SLUO: PS467_33050(shc)
STPB: QR97_14680 QR97_33695
SRPA: HEP86_03260 HEP86_33755(shc)
SMIB: SMIR_00885(shc)
SCAJ: O1G22_06935(shc)
STRW: QHG49_06010(shc)
STRL: HEP84_43725(shc) HEP84_46950
SRPZ: HEP85_33390(shc)
SCHE: QRN89_31175(shc)
SGLY: P8A20_03390(shc)
SCAT: P8A18_30535(shc)
STII: DRB96_19725(shc) DRB96_23485(shc)
STIC: DRB89_19815(shc) DRB89_23315(shc)
SABD: N8I86_31420(shc)
STRV: EZV63_32085(shc)
SPIH: ABXR15_01960(shc) ABXR15_24530
SMOD: POD33_33625(shc)
SPOF: P8A21_35360(shc)
SCT: SCAT_4943(shc) SCAT_5607
SCY: SCATT_49380 SCATT_56060
KSK: KSE_17590
KAB: B7C62_21470 B7C62_32710
KAU: B6264_00545
KIT: CFP65_0190 CFP65_6584
KIS: HUT16_07505(shc)
KCH: O1G21_07955(shc)
YIA: LO772_08835(shc) LO772_31665
STRH: GXP74_14415(shc)
ABRY: NYE86_23665(shc)
AGLA: OIE69_08875(shc)
AREV: RVR_8546 RVR_8688
ALX: LVQ62_17075(shc)
KSL: OG809_35695(shc)
ACTW: F7P10_06045(shc)
AGRA: AGRA3207_001324(shc)
AMAZ: LUW76_34310(shc)
ACIR: OG979_25100(shc) OG979_31070(shc)
SPIQ: OHA34_11220(shc)
ACTQ: OG417_26130(shc)
NOW: GBF35_34755(shc)
NCX: Nocox_41615(shc)
MHAI: OHB01_28800(shc)
FRA: Francci3_0823
FAL: FRAAL1432(shc1) FRAAL2491(shc2)
FRE: Franean1_4758 Franean1_5713
FSY: FsymDg_1170
FRI: FraEuI1c_2682 FraEuI1c_5917
ACE: Acel_1697
BSD: BLASA_0211(shc)
SEN: SACE_4327(shc1) SACE_4648
SACG: FDZ84_19500 FDZ84_33290(shc) FDZ84_37270
SVI: Svir_23080
SACC: EYD13_11020(shc1) EYD13_12855(shc2)
AMQ: AMETH_4077(shc1)
AMYC: CU254_13920(shc)
AMYY: YIM_15135(shc)
AACD: LWP59_21025(shc)
ATHM: L1857_23265(shc)
ARHD: VSH64_06060(shc)
ACYN: ORV05_18535(shc)
ACAB: QRX50_40395(shc)
AMYD: K1T34_36170(shc)
ABAR: AMYBAR_004220(shc)
AMYS: CVV72_08060
PDX: Psed_3680
PSEH: XF36_18915
PHH: AFB00_04195 AFB00_16765
APRE: CNX65_21970
AMI: Amir_4385
SSYI: EKG83_15250 EKG83_31035
KAL: KALB_4044
KUT: JJ691_03820(shc_1) JJ691_30070(shc_2)
KBR: Q4V65_08940(shc)
ACTI: UA75_12830
ACAD: UA74_12750
AHG: AHOG_12025(shc)
ALO: CRK61965
PMAD: BAY61_14060
ACTU: Actkin_02998(shc)
CROS: N8J89_18605 N8J89_23875
UME: RM788_02130
MAU: Micau_3713
MIL: ML5_4686
MICB: MicB006_2812
MICH: FJK98_09315
MCHL: PVK74_08985
MFEU: H1D33_24625
PLAB: C6361_04775(shc)
PLAT: C6W10_01300(shc)
PFLA: Pflav_027740
PSUU: Psuf_090700
ATL: Athai_51160
ASER: Asera_23680
PRY: Prubr_63970
DFU: Dfulv_13510(shc)
DROS: Drose_12545(shc)
DACT: KZZ52_26515(shc)
CAI: Caci_6664
AEY: CDG81_09445(shc)
JCY: M6B22_00940(shc)
RXY: Rxyl_2756
BSOL: FSW04_24315(shc)
SBAE: DSM104329_05202(shc)
SYN: slr2089(shc)
SYZ: MYO_114140(shc)
SYY: SYNGTS_1402(shc)
SYT: SYNGTI_1402(shc)
SYS: SYNPCCN_1401(shc)
SYQ: SYNPCCP_1401(shc)
SYJ: D082_00070(shc)
SYO: C7I86_07260(shc)
SYNH: HTZ78_11340(shc)
SYNS: OLK001_32350
SYNE: Syn6312_1461
SYNP: Syn7502_03476
WNA: KA717_14815(shc)
CYN: Cyan7425_3575
TVN: NIES2134_122340(shc)
SLW: BRW62_00510
TEL: tlr2309(shc)
THN: NK55_08140(sqhC)
THEC: FFX45_04995(shc)
THEY: JW907_09020(shc)
TSQ: D3A95_07990(shc)
AMR: AM1_4845(shc)
ACAM: HRE53_19835(shc)
LEN: LEP3755_00050
LBO: LBWT_51590
KOV: K9N68_23475(shc)
LSC: KIK02_09045(shc)
LSK: J5X98_02115(shc)
SFRI: RBJ76_14945(shc)
HHG: XM38_041670(shc)
GEN: GM3709_1659
GEE: GM3708_231
CAN: Cyan10605_1649
MAR: MAE_44950(shc)
MPK: VL20_2504
MIQ: B5D77_03340
MVZ: myaer102_18990(shc)
CYU: UCYN_09140
CYT: cce_4510(shc)
CWA: CwatDRAFT_6219
CYP: PCC8801_2842
CYH: Cyan8802_3254
CYC: PCC7424_3320
CYJ: Cyan7822_0123
TER: Tery_0727
PAGH: NIES204_29660
PPSU: NO713_00417(DCD)
PRUN: PCC7821_03029(DCD)
PHOR: JWS08_00180(shc)
PYH: NEA10_10000(shc)
MIC: Mic7113_5949
MPRO: BJP34_24710
GVI: glr4057(shc)
GLJ: GKIL_2413(shc)
GML: ISF26_20930(shc)
ANA: all0775
NPU: Npun_R6245
NOS: Nos7107_0414
NOP: Nos7524_3073 Nos7524_5159
NON: NOS3756_03280
NFL: COO91_07277
NOE: CLI64_14195(shc)
NSH: GXM_01577
NED: HUN01_06045(shc)
NPZ: ACX27_19850
NLK: NIES25_18010
NCW: NIES2107_11860
NCF: ANSO36C_39840(shc)
NOST: GJB62_09335(shc)
NOSU: JYQ62_00060(shc)
NOSQ: PQG02_07370(shc)
AVA: Ava_4671
ANB: ANA_C12765
ACY: Anacy_5203
AWA: AA650_12920
ANN: EH233_26715(shc)
CSG: Cylst_2445
RSIN: B6N60_02202
HBQ: QI031_29190(shc)
CALO: Cal7507_0308
CALT: Cal6303_3753
CALN: NIES2098_01140
MDP: NIES3275_25380
FIS: FIS3754_26860
DOU: BMF77_04608(shc)
DFS: HGD76_07565(shc)
DHT: NG743_09555(shc)
DCM: NIES806_23010
DOT: EZY12_07090(shc)
DOZ: HEP80_08890(shc)
DOC: HEQ26_22500(shc)
CCUR: IAR63_14650(shc)
CRK: L3I90_15740(shc)
AFLO: HEQ12_11025(shc)
STOQ: K2F26_04130(shc)
SKV: NIES73_13790
RCS: NIES932_04490
TOQ: HCG51_07545(shc)
TTQ: NIES37_46900
ALAX: NIES50_39650
SCYT: SAMD_37110 SAMD_47790
SCYS: NIES4073_48250
BSEN: DP114_15255(shc)
BOX: DP113_15195(shc)
NCN: BZZ01_14710
PLP: Ple7327_2716
SCS: Sta7437_3936
STAN: STA3757_10830
GLT: GlitD10_2049(sqhC)
GCY: LQF76_07430(shc)
CEO: ETSB_1175(shc)
CER: RGRSB_1837(shc)
CEEC: P3F56_05900(shc)
KBS: EPA93_16020(shc) EPA93_17550 EPA93_17590
KBB: ccbrp13_17780
CCZ: CCALI_00139 CCALI_01615
VAB: WPS_25140(shc)
BANA: BARAN1_1143(shc)
BIH: BIP78_1402
MOX: DAMO_0045(shc)
HALJ: G9465_03285
IHO: Igni_0441
 » show all
Reference
1  [PMID:15136801]
  Authors
Hoshino T, Nakano S, Kondo T, Sato T, Miyoshi A
  Title
Squalene-hopene cyclase: final deprotonation reaction, conformational analysis for the cyclization of (3R,S)-2,3-oxidosqualene and further evidence for the requirement of an isopropylidene moiety both for initiation of the polycyclization cascade and for the formation of the 5-membered E-ring.
  Journal
Org Biomol Chem 2:1456-70 (2004)
DOI:10.1039/b401172d
Reference
2  [PMID:15056909]
  Authors
Sato T, Kouda M, Hoshino T
  Title
Site-directed mutagenesis experiments on the putative deprotonation site of squalene-hopene cyclase from Alicyclobacillus acidocaldarius.
  Journal
Biosci Biotechnol Biochem 68:728-38 (2004)
DOI:10.1271/bbb.68.728
Other DBs
ExplorEnz - The Enzyme Database: 4.2.1.129
IUBMB Enzyme Nomenclature: 4.2.1.129
ExPASy - ENZYME nomenclature database: 4.2.1.129
BRENDA, the Enzyme Database: 4.2.1.129
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