| Entry |
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| Name |
gluconate dehydratase;
D-gluconate dehydratase;
D-gluconate hydro-lyase
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| Class |
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
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| Sysname |
D-gluconate hydro-lyase (2-dehydro-3-deoxy-D-gluconate-forming)
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| Reaction(IUBMB) |
D-gluconate = 2-dehydro-3-deoxy-D-gluconate + H2O [RN: R01538]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
2-dehydro-3-deoxy-D-gluconate [CPD: C00204];
H2O [CPD: C00001]
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| Comment |
The enzyme shows no activity with D-galactonate [2]. cf. EC 4.2.1.140, gluconate/galactonate dehydratase.
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| History |
EC 4.2.1.39 created 1972
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| Pathway |
| ec01120 | Microbial metabolism in diverse environments |
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| Reference |
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| Authors |
Andreesen JR, Gottschalk G. |
|---|
| Title |
The occurrence of a modified Entner-doudoroff pathway in Clostridium aceticum. |
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| Journal |
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| Reference |
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| Authors |
Bender R, Gottschalk G |
|---|
| Title |
Purification and properties of D-gluconate dehydratase from Clostridium pasteurianum. |
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| Journal |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 4.2.1.39 |
| ExPASy - ENZYME nomenclature database: | 4.2.1.39 |
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| LinkDB |
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