KEGG   ENZYME: 4.2.1.43
Entry
EC 4.2.1.43                 Enzyme                                 
Name
2-dehydro-3-deoxy-L-arabinonate dehydratase;
2-keto-3-deoxy-L-arabinonate dehydratase;
2-dehydro-3-deoxy-L-arabinonate hydro-lyase
Class
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
Sysname
2-dehydro-3-deoxy-L-arabinonate hydro-lyase (2,5-dioxopentanoate-forming)
Reaction(IUBMB)
2-dehydro-3-deoxy-L-arabinonate = 2,5-dioxopentanoate + H2O [RN:R02278]
Reaction(KEGG)
R02278
Substrate
2-dehydro-3-deoxy-L-arabinonate [CPD:C00684]
Product
2,5-dioxopentanoate [CPD:C00433];
H2O [CPD:C00001]
History
EC 4.2.1.43 created 1972
Pathway
ec00053  Ascorbate and aldarate metabolism
ec01100  Metabolic pathways
Orthology
K13876  2-keto-3-deoxy-L-arabinonate dehydratase
Genes
CTU: CTU_06570
KMI: VW41_03260
CAF: AL524_22380
EBT: EBL_c33280
KCO: BWI95_18060
BUF: D8682_18995
BAGE: BADSM9389_06400
BFT: MNO13_03305
SUPE: P0H77_05650
EBB: F652_2947
SPE: Spro_0707
SLQ: M495_02890
SQU: E4343_13080
ROX: BV494_01165
RVC: J9880_24230
SOD: Sant_0675
EPE: CI789_02275
PMAK: PMPD1_3742
HAV: AT03_19840
HPAR: AL518_06710
OPO: DSM2777_05585
LPV: HYN51_09415
PRAG: EKN56_20130
RFO: REIFOR_01233
LLP: GH975_02685
RPI: Rpic_3006
RPF: Rpic12D_2596
RPJ: N234_21925
RMN: TK49_06590
RWE: KOL96_20620
REH: H16_B0213(dapA2)
CNC: CNE_2c01980(dapA1)
CUH: BJN34_21090
CTI: RALTA_B0220
CBW: RR42_s0473
CGD: CR3_3974(araD)
CCUP: BKK81_02470
CPAU: EHF44_25915
COX: E0W60_07020
CCAX: KZ686_23220
CUK: KB879_18770
CNAN: A2G96_21660
BTE: BTH_II1630
BTQ: BTQ_4919(araD)
BTJ: BTJ_3543(araD)
BTZ: BTL_4392(araD)
BTD: BTI_5591(araD)
BTV: BTHA_3565(araD)
BTHE: BTN_4043(araD)
BTHM: BTRA_4050(araD)
BTHA: DR62_4079
BTHL: BG87_4375(AraD)
BHG: I6G56_24130
BUD: AQ610_26805
BVI: Bcep1808_3834
BVE: AK36_4877(araD)
BUR: Bcep18194_B0042 Bcep18194_B3057
BCM: Bcenmc03_4375 Bcenmc03_4586 Bcenmc03_6235
BCH: Bcen2424_5643 Bcen2424_5804 Bcen2424_6637
BCJ: BCAM0104 BCAM2800
BCEN: DM39_5046(araD) DM39_6177(araD)
BCEW: DM40_3367(araD)
BCEO: I35_6679
BAM: Bamb_3398 Bamb_4923 Bamb_5070
BAC: BamMC406_3210 BamMC406_5478
BMJ: BMULJ_05321(dapA)
BMU: Bmul_3204
BMK: DM80_4584(araD)
BMUL: NP80_3349(araD)
BCT: GEM_3979 GEM_5481 GEM_5607
BCED: DM42_5188(araD)
BCEP: APZ15_24595
BDL: AK34_5007(araD)
BPYR: ABD05_20735 ABD05_21635 ABD05_31625
BCON: NL30_17845 NL30_24965
BUB: BW23_3987(araD) BW23_4351(araD)
BDF: WI26_15735 WI26_26560
BLAT: WK25_29415
BTEI: WS51_10640
BSEM: WJ12_16065 WJ12_33860
BPSL: WS57_00265 WS57_05740
BMEC: WJ16_20380 WJ16_32370
BSTG: WT74_22175 WT74_32755
BSTL: BBJ41_21670
BANN: JFN94_18020 JFN94_18890 JFN94_26305
BARI: NLX30_22220 NLX30_23130
BAEN: L3V59_22125
BSER: R0290_20450 R0290_21250
BGL: bglu_1g17850
BGU: KS03_2640(araD)
BUG: BC1001_4105
BGF: BC1003_5311
BGD: bgla_2g13470
BGO: BM43_5015(araD)
BYI: BYI23_B013290 BYI23_D004040 BYI23_D009640
BUK: MYA_3489
BUE: BRPE67_BCDS00220 BRPE67_DCDS05750 BRPE67_DCDS11690
BUL: BW21_5279(araD)
BUQ: AC233_29080
BGP: BGL_1c19710
BPLA: bpln_1g18020
BUM: AXG89_11870 AXG89_22230
BUI: AX768_05665 AX768_24750
BURK: DM992_25760 DM992_26925 DM992_37145
BPH: Bphy_6711
BGE: BC1002_4374
BPX: BUPH_00687
BPY: Bphyt_4575
BFN: OI25_5423 OI25_6642
BCAI: K788_0005071 K788_0008592
PSPW: BJG93_24260
PARA: BTO02_21210
PARB: CJU94_24595 CJU94_26045
PHS: C2L64_22580 C2L64_36150 C2L64_52290
PTER: C2L65_25020 C2L65_31360
PGP: CUJ91_27135
PCJ: CUJ87_17870
PTS: CUJ90_19400
PCAF: DSC91_000932 DSC91_002982
PMEG: FNZ07_06590
PTRO: G5S35_23715 G5S35_32515 G5S35_33960
PGIS: I6I06_18090 I6I06_25055
PACP: FAZ97_24140 FAZ97_34310
PACS: FAZ98_28815
PEW: KZJ38_22555
PBRY: NDK50_12435 NDK50_25490
PSAA: QEN71_12585 QEN71_31040
PKF: RW095_10970
PBON: QS306_09900
PPAI: E1956_35875
PHUN: U0042_09665 U0042_26625
PLAD: PPGU16_14980 PPGU16_41480 PPGU16_74260
CABA: SBC2_14340(dapA_3) SBC2_66650(araD)
BUO: BRPE64_BCDS00230 BRPE64_CCDS05510 BRPE64_DCDS07830
CABK: NK8_42780 NK8_45750 NK8_66410
TVL: FAZ95_24110
TCAR: U0034_21535
BHO: D560_1639
BHM: D558_1627
BBRO: BAU06_17390
BFZ: BAU07_05105
BPDZ: BBN53_13505
AXY: AXYL_04351
AXO: NH44784_063331
AXN: AX27061_4574
AXX: ERS451415_04605(yagE_2)
ADT: APT56_21015
AIS: BUW96_10930
ASW: CVS48_23105
ACHR: C2U31_09970 C2U31_16375
ACHB: DVB37_17495
ADY: HLG70_02415
APES: FOC84_24125
AAEG: RA224_11345
POLL: OEG81_15295
CDN: BN940_14416
ODI: ODI_R4258
PARK: LSG25_17845
RFR: Rfer_0453 Rfer_1026
RSB: RS694_18415
RHY: RD110_12005
RHOB: HTY51_17305
RMK: RAN89_02985
POL: Bpro_2837
PVAC: HC248_02301(araD)
ACK: C380_10450
ACIO: EAG14_03785
ARAD: KI609_13600
ACIQ: ACDW_09720
ACIV: EXV95_02870
AAV: Aave_2247
AAA: Acav_2893 Acav_4648
AMON: H9L24_15665
VEI: Veis_2707 Veis_3541
DAC: Daci_4983
DEL: DelCs14_1862
DTS: BI380_30715
DHK: BO996_22910
DLA: I6G47_31125
VAP: Vapar_1052
VPE: Varpa_1121
VPD: VAPA_1c11050 VAPA_2c00550(dapA)
VAA: AX767_04455
VBO: CKY39_05220
VAM: C4F17_13930
VAZ: H7F35_17605
VAV: IG196_03600
CTT: CtCNB1_3908
CTES: O987_23535
AANT: HUK68_00055
HPSE: HPF_09020(araD)
HGR: DW355_08820
RDP: RD2015_2629
ROI: N4261_12725
ATER: MW290_14215 MW290_26310
HSE: Hsero_1368(dapA)
HSZ: ACP92_06865
HHT: F506_04770
HRB: Hrubri_1189(dapA)
HEE: hmeg3_00985
HHF: E2K99_06845
HFR: G5S34_07085
HEW: HBDW_12620
GLC: JQN73_14925
XYK: GT347_21915
URU: DSM104443_00662(araD_1)
MES: Meso_3971
AAK: AA2016_4939
AMIH: CO731_04159(yagE_2)
RPOD: E0E05_09145
ORM: HTY61_17225
SMX: SM11_pC1295
SMER: DU99_23820
SIX: BSY16_5632
EAD: OV14_a1105(dapA)
RHR: CKA34_25505
SHZ: shn_14790
BJA: bll7953(bll7953)
BJU: BJ6T_12720
BJP: RN69_06220
BRA: BRADO1813
BBT: BBta_2133
BRS: S23_65840
AOL: S58_57230
BRC: BCCGELA001_04085 BCCGELA001_29135
BRAD: BF49_3436
BIC: LMTR13_30020
BRO: BRAD285_5472(araD)
BRK: CWS35_02785
BOT: CIT37_03940 CIT37_08040
BRQ: CIT40_29215
BGQ: X265_04835
BGZ: XH91_05125
BSYM: CIT39_28240
BBET: F8237_12250
BARH: WN72_04140 WN72_09275
BVZ: BRAD3257_8478(araD)
BEL: BE61_14750(dapA)
BDG: LPJ38_08405 LPJ38_36410
BSEP: HAP48_0019235
BQB: J4P68_0022725
BBAN: J4G43_004605
BCAN: BcanWSM471_34955
BAUT: QA635_38820
BBRA: QA636_40230
BGK: IC762_07845
BCOU: IC761_04360
BPAH: QA639_39190
BXN: I3J27_36690
BROS: QUH67_27315
BRAZ: LRP30_02625
BOY: LQG66_14955
BRAY: ML401_31735
RHOR: ONR75_14845
BVV: BHK69_13550 BHK69_23230
BVES: QO058_07785 QO058_24285
BOP: AXW83_15040
BOS: BSY19_2309 BSY19_4559
BOI: BLM15_13485 BLM15_28230
BOF: FQV39_01140 FQV39_05845 FQV39_14530
BOW: NWE53_24210
BOSE: RMR04_20735
BAPA: BBC0178_012570
XAU: Xaut_1021
STAR: G3545_22980
SNO: Snov_0118
APRA: G3A50_11630
APOL: K9D25_15455
MRD: Mrad2831_4925
MOR: MOC_5613
MAQU: Maq22A_c05765(dapA)
MPHY: MCBMB27_04363
MEE: DA075_26795
METX: A3862_07295
MMES: MMSR116_28745
MTEA: DK419_06420
MIND: mvi_28100
MTAD: M6G65_22580
MOC: BB934_07055
MIV: C4E04_02010
MTEZ: HPT29_020335
MLD: U0023_03140
BID: Bind_3080
CHEL: AL346_04990
DEA: FPZ08_12195
DRP: PSQ90_04410
MMYR: MXMO3_02356
HDI: HDIA_0216(araD)
AALA: IGS74_14615
AALM: LUX29_16530
AUZ: Sa4125_16180
JIE: OH818_12675
NOH: G5V57_05530
LAP: ACP90_11030
LABT: FIU93_14080(araD1) FIU93_16605(araD2)
LAGG: B0E33_22965
PHR: C6569_02935
PSTG: E8M01_07905
PAQT: E8L99_18140
LIZ: LGH83_06415
ACUT: MRB58_07415
SIL: SPOA0244
DSH: Dshi_2446
OAR: OA238_c12510
CBAK: DA792_17235
MALG: MALG_03895 MALG_04381 MALG_04456
YPAC: CEW88_03665
YAN: AYJ57_10815
SULZ: C1J03_13130
SULD: B5M07_05330
SINL: DSM14862_02690(araD)
RID: RIdsm_01841(araD)
AHT: ANTHELSMS3_03458
SAGU: CDO87_19365
THAA: CFI11_20005
OCD: FHY55_19120
MALU: KU6B_19310
PALX: GQA70_14560
TRY: QF118_16770
PDE: Pden_4666
PAMI: JCM7686_3316
PYE: A6J80_10095
PCON: B0A89_02490
PZH: CX676_00745
PARO: CUV01_13830
PMUT: DPM13_08295
PSAN: HGN31_05465
PALS: PAF20_17050
PTP: RCA23_c06720 RCA23_c06790(dapA3) RCA23_c23430
RHC: RGUI_3959
RMB: K529_014365 K529_016090
RBZ: B9057_15760
LVS: LOKVESSMR4R_03077(araD)
SALO: EF888_19155
LIT: FPZ52_15850
PALW: PSAL_020910(araD)
PSHQ: F3W81_19105
PPAF: I8N54_02195
FAP: GR316_11125
PBAE: P8S53_17450
NOV: TQ38_023065
SPHI: TS85_03755
ACR: Acry_2738
AMV: ACMV_30670
RGI: RGI145_17600
ROS: CTJ15_16450
RMUC: FOB66_22025
RMT: IAI58_08570
RCV: PFY06_19765
RAP: RHOA_2195
ACIM: GT370_05260
AZL: AZL_e03630(dapA)
ALI: AZOLI_p50377(araD)
ABS: AZOBR_p440160
ABQ: ABAZ39_31595
ABF: AMK58_27385
ATI: AL072_31000
AHU: A6A40_14230
AZT: TSH58p_21360
AZM: DM194_26435
AZZ: DEW08_22000
AOZ: HUE56_23205 HUE56_26165
AARE: D3093_27765 D3093_30990
AZS: E6C72_28390
SKT: IGS68_08980 IGS68_30525
SMUC: JL100_018400 JL100_031430
SROE: JL101_017100 JL101_031855
HTQ: FRZ44_40650
NACI: NUH88_17205
THAR: T8K17_07875
PAUN: MJA45_14130
COHL: J4772_31980
NTR: B0W44_15610
SRN: A4G23_03540(dapA_3)
MOY: CVS54_01202(araD)
HEA: HL652_17435 HL652_17800
PDEL: JCQ34_14735
PSFE: NG819_07990
SATK: SA2016_0951
BCV: Bcav_3940
MICG: GJV80_08325
NOA: BKM31_21025
NAK: EH165_10140
AAB: A4R43_04445
AMYY: YIM_17550(araD)
AACD: LWP59_14525
PAUT: Pdca_64040
ACTI: UA75_20040
ACAD: UA74_19550
PMAD: BAY61_16470
PVS: A1sIA79_05270
NHI: B1s21160_02175
LMAJ: GKN94_10155
MTAR: DF168_00716(araD_1) DF168_00971(araD_2)
RUL: UC8_01250(araD)
ROL: CA51_31580(dapA_3)
RUV: EC9_20450(dapA_1)
LCRE: Pla8534_61970(araD)
AAGG: ETAA8_26400(araD)
PBS: Plabr_4261
PLS: VT03_23390(dapA_3)
FMR: Fuma_05619(araD)
GMR: GmarT_22610(araD)
GIM: F1728_03120
GPN: Pan110_21890(araD)
GFM: Enr17x_23730(araD)
SDYN: Mal52_40300(araD_1) Mal52_45600(araD_2)
PLON: Pla110_17110(araD_1) Pla110_46420(araD_2)
TPLA: ElP_72180(dapA)
PFER: IRI77_21920 IRI77_22525
ABAC: LuPra_02639(araD_1)
FLA: SY85_11775
FLC: KJS93_18565
CMR: Cycma_0043
SLI: Slin_0609
SRD: SD10_11625
SPIK: EXU85_24685
SFOL: H3H32_14580
DPF: ON006_20665
RUN: DR864_11930 DR864_18420
RUP: DTQ70_25045
FAC: FACI_IFERC01G0501
 » show all
Reference
1  [PMID:5954356]
  Authors
Stoolmiller AC, Abeles RH.
  Title
Formation of alpha-ketoglutaric semialdehyde from L-2-keto-3-deoxyarabonic acid and isolation of L-2-keto-3-deoxyarabonate dehydratase from Pseudomonas saccharophila.
  Journal
J Biol Chem 241:5764-71 (1966)
Other DBs
ExplorEnz - The Enzyme Database: 4.2.1.43
IUBMB Enzyme Nomenclature: 4.2.1.43
ExPASy - ENZYME nomenclature database: 4.2.1.43
BRENDA, the Enzyme Database: 4.2.1.43
CAS: 37263-10-8
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