KEGG   ENZYME: 4.2.3.147
Entry
EC 4.2.3.147                Enzyme                                 
Name
pimaradiene synthase;
PbmPIM1;
PcmPIM1
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
Sysname
(+)-copalyl diphosphate-lyase (pimara-8(14),15-diene-forming)
Reaction(IUBMB)
(+)-copalyl diphosphate = pimara-8(14),15-diene + diphosphate [RN:R06299]
Reaction(KEGG)
R06299
Substrate
(+)-copalyl diphosphate [CPD:C11901]
Product
pimara-8(14),15-diene [CPD:C06086];
diphosphate [CPD:C00013]
Comment
Isolated from the plants Pinus banksiana (jack pine) and Pinus contorta (lodgepole pine).
History
EC 4.2.3.147 created 2014
Pathway
ec00904  Diterpenoid biosynthesis
ec01110  Biosynthesis of secondary metabolites
Orthology
K20515  pimaradiene synthase
Reference
1  [PMID:23370714]
  Authors
Hall DE, Zerbe P, Jancsik S, Quesada AL, Dullat H, Madilao LL, Yuen M, Bohlmann J
  Title
Evolution of conifer diterpene synthases: diterpene resin acid biosynthesis in lodgepole pine and jack pine involves monofunctional and bifunctional diterpene synthases.
  Journal
Plant Physiol 161:600-16 (2013)
DOI:10.1104/pp.112.208546
  Sequence
[ag:AFU73867 AFU73868]
Other DBs
ExplorEnz - The Enzyme Database: 4.2.3.147
IUBMB Enzyme Nomenclature: 4.2.3.147
ExPASy - ENZYME nomenclature database: 4.2.3.147
BRENDA, the Enzyme Database: 4.2.3.147
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