| Entry |
|
| Name |
ent-atiserene synthase;
IrKSL4;
AcKSL1;
ApKSL1;
AtKSL1;
AsKSL1
|
| Class |
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
|
| Sysname |
ent-copalyl-diphosphate diphosphate-lyase (cyclizing, ent-atiserine-forming)
|
| Reaction(IUBMB) |
ent-copalyl diphosphate = ent-atiserene + diphosphate [RN: R11850]
|
| Reaction(KEGG) |
|
| Substrate |
ent-copalyl diphosphate [CPD: C06089]
|
| Product |
|
| Comment |
Isolated from the plant Isodon rubescens and several species of Aconitum as well as species of Streptomyces.
|
| History |
EC 4.2.3.185 created 2017
|
| Reference |
|
| Authors |
Smanski MJ, Yu Z, Casper J, Lin S, Peterson RM, Chen Y, Wendt-Pienkowski E, Rajski SR, Shen B. |
| Title |
Dedicated ent-kaurene and ent-atiserene synthases for platensimycin and platencin biosynthesis. |
| Journal |
|
| Reference |
|
| Authors |
Jin B, Cui G, Guo J, Tang J, Duan L, Lin H, Shen Y, Chen T, Zhang H, Huang L |
| Title |
Functional Diversification of Kaurene Synthase-Like Genes in Isodon rubescens. |
| Journal |
|
| Sequence |
|
| Reference |
|
| Authors |
Tian M, Jin B, Chen L, Ma R, Ma Q, Li X, Chen T, Guo J, Ge H, Zhao X, Lai C, Tang J, Cui G, Huang L. |
| Title |
Functional diversity of diterpene synthases in Aconitum plants. |
| Journal |
|
| Other DBs |
| ExPASy - ENZYME nomenclature database: | 4.2.3.185 |
|
| LinkDB |
|