ENZYME: 4.2.3.213
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Entry
EC 4.2.3.213 Enzyme
Name
colleterpenol synthase;
CgCS
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
BRITE hierarchy
Sysname
pentaprenyl-diphosphate diphosphate-lyase [cyclizing, colleterpenol-forming]
Reaction(IUBMB)
all-trans-hexaprenyl diphosphate + H2O = colleterpenol + diphosphate [RN:
R13228
]
Reaction(KEGG)
R13228
Reaction
Substrate
all-trans-hexaprenyl diphosphate [CPD:
C01230
];
H2O [CPD:
C00001
]
Product
colleterpenol [CPD:
C22838
];
diphosphate [CPD:
C00013
]
Comment
Isolated from Colletotrichum gloeosporioides, a pathogenic fungus that causes bitter rot in variety of crops.
History
EC 4.2.3.213 created 2023
Reference
1 [PMID:
35650436
]
Authors
Tao H, Lauterbach L, Bian G, Chen R, Hou A, Mori T, Cheng S, Hu B, Lu L, Mu X, Li M, Adachi N, Kawasaki M, Moriya T, Senda T, Wang X, Deng Z, Abe I, Dickschat JS, Liu T.
Title
Discovery of non-squalene triterpenes.
Journal
Nature 606:414-419 (2022)
DOI:
10.1038/s41586-022-04773-3
Other DBs
ExplorEnz - The Enzyme Database:
4.2.3.213
IUBMB Enzyme Nomenclature:
4.2.3.213
ExPASy - ENZYME nomenclature database:
4.2.3.213
BRENDA, the Enzyme Database:
4.2.3.213
LinkDB
All DBs
DBGET
integrated database retrieval system
