KEGG   ENZYME: 4.2.3.219
Entry
EC 4.2.3.219                Enzyme                                 
Name
(2E)-alpha-cericerene synthase;
EvSS
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
Sysname
geranylfarneyl-diphosphate diphosphate-lyase (cyclizing, (2E)-alpha-cericerene-forming)
Reaction(IUBMB)
geranylfarnesyl diphosphate = (2E)-alpha-cericerene + diphosphate [RN:R13235]
Reaction(KEGG)
R13235
Substrate
geranylfarnesyl diphosphate [CPD:C04217]
Product
(2E)-alpha-cericerene [CPD:C22845];
diphosphate [CPD:C00013]
Comment
A sesterterpenoid synthase enzyme isolated from the fungus Aspergillus stellatus.
History
EC 4.2.3.219 created 2023
Reference
1  [PMID:26546087]
  Authors
Qin B, Matsuda Y, Mori T, Okada M, Quan Z, Mitsuhashi T, Wakimoto T, Abe I.
  Title
An Unusual Chimeric Diterpene Synthase from Emericella variecolor and Its Functional Conversion into a Sesterterpene Synthase by Domain Swapping.
  Journal
Angew Chem Int Ed Engl 55:1658-61 (2016)
DOI:10.1002/anie.201509263
Other DBs
ExplorEnz - The Enzyme Database: 4.2.3.219
IUBMB Enzyme Nomenclature: 4.2.3.219
ExPASy - ENZYME nomenclature database: 4.2.3.219
BRENDA, the Enzyme Database: 4.2.3.219
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