KEGG ENZYME: 4.2.3.46

ENZYME: 4.2.3.46

Entry

EC 4.2.3.46                 Enzyme

Name

alpha-farnesene synthase;
(E,E)-alpha-farnesene synthase;
AFS1;
MdAFS1

Class

Lyases;
Carbon-oxygen lyases;
Acting on phosphates

Sysname

(2E,6E)-farnesyl-diphosphate lyase [(3E,6E)-alpha-farnesene-forming]

Reaction(IUBMB)

(2E,6E)-farnesyl diphosphate = (3E,6E)-alpha-farnesene + diphosphate [RN:R08696]

Reaction(KEGG)

R08696

Substrate

(2E,6E)-farnesyl diphosphate [CPD:C00448]

Product

(3E,6E)-alpha-farnesene [CPD:C09665];
diphosphate [CPD:C00013]

History

EC 4.2.3.46 created 2010

Pathway

ec00909

Sesquiterpenoid and triterpenoid biosynthesis

ec01110

Biosynthesis of secondary metabolites

Orthology

K14173

alpha-farnesene synthase

Genes

CPAP:

110812202

CIT:	102618658 102625123

CIC:	CICLE_v10014790mg CICLE_v10018045mg

PVY:	116105216 116107515

MINC:

123218733 123218734

TCC:

18597031

GRA:

105775103

GHI:	107925033 107941108

GAB:

108451362

HSYR:

120174784 120191020

DZI:	111275141 111278493 111278668 111318785

EGR:	104429922 104441154 104441155 104442740 104442741 104442742 104442748 104442750 120292434 120292508 120292515 120292516

RARG:

115739701 115739702 115739772 115739773

GMX:	100805428(TPS27) 100812119(TPS21)

GSJ:

114374943

PVU:

137823689

VRA:

106778111

VAR:

108339494

VUN:

114170633

VUM:

124843652

CCAJ:

109798516 109816863

APRC:

113865769

MTR:

11422412

TPRA:

123924643

CAM:

101497499

PSAT:

127106806

VVO:

131606613

LJA:

130747880

LANG:

109353649

PCIN:

129315248

QSA:	O6P43_032258 O6P43_032264 O6P43_032265 O6P43_032375

FVE:

101301453

AANS:

126789204

RCN:	112202294 112203530

PPER:

18779527 18780802 18781109

PMUM:

103324592 103325568 103325630 103325632

PAVI:

110746466 110760301 110760313 110768757

PDUL:

117624979 117625783 117625956

MDM:

103446592

MSYL:

126586068

PCOX:

137729943

ZJU:

107421480

MNT:

21397955

CSAV:

115707439

RCU:

8267421

MEAN:

126679453

JCU:

105650120

HBR:

110646158

POP:

7495294

PEU:

105107359

PALZ:

118031650 118031653

PNZ:	133702698 133703982

JRE:	109006431 109006432 109006436 109006437 109011554

CILL:

122278293 122278773 122279849

CAVE:

132171894 132171897

AGLU:

133868846

QSU:	111988842 111988873 111989179 111989188

QLO:	115974000 115992038 115992039

TWL:

120005010

VVI:

100240859

VRI:

117923379

SLY:	101253272 101258440 101260508

SPEN:

107010686 107010846 107013096

SOT:	102600675 102604608

SSTN:

125846823 125848662 125848698

SDUL:

129872308 129872311 129875112 129895341

CANN:

107857095 107858222 107859528 107866137

LBB:	132611312 132612326 132622302 132624614 132625094

NTA:	107765628 107779472 107800233 107814194

NSY:	104242876 138886306

NTO:	104107440 104113853 104116491

INI:

109167313

ITR:

116030598

SIND:

105175393

OEU:	111368535 111368536

EGT:

105968665

SSPL:

121746043

SMIL:

130985658 130985718

SHIS:

125190876

LSV:

111897134

DCR:	108198720 108199225

CSIN:

114257853 114266406 114288844

BVG:

104883054

CQI:	110687266 110693457

ATRI:

130815790

MOF:

131153290

MING:

122059084 122060221 122067625 122084919

TSS:	122643319 122672262

» show all

Reference

1 [PMID:14740213]

Authors

Pechous SW, Whitaker BD

Title

Cloning and functional expression of an ( E, E)-alpha-farnesene synthase cDNA from peel tissue of apple fruit.

Journal

Planta 219:84-94 (2004)
DOI:10.1007/s00425-003-1191-4

Sequence

[mdm:103446592]

Reference

2 [PMID:19181671]

Authors

Green S, Squire CJ, Nieuwenhuizen NJ, Baker EN, Laing W

Title

Defining the potassium binding region in an apple terpene synthase.

Journal

J Biol Chem 284:8661-9 (2009)
DOI:10.1074/jbc.M807140200

Sequence

[mdm:103446592]

Reference

3 [PMID:19516075]

Authors

Nieuwenhuizen NJ, Wang MY, Matich AJ, Green SA, Chen X, Yauk YK, Beuning LL, Nagegowda DA, Dudareva N, Atkinson RG

Title

Two terpene synthases are responsible for the major sesquiterpenes emitted from the flowers of kiwifruit (Actinidia deliciosa).

Journal

J Exp Bot 60:3203-19 (2009)
DOI:10.1093/jxb/erp162

Other DBs

ExplorEnz - The Enzyme Database:

4.2.3.46

IUBMB Enzyme Nomenclature:

4.2.3.46

ExPASy - ENZYME nomenclature database:

4.2.3.46

BRENDA, the Enzyme Database:

4.2.3.46

LinkDB

DBGET integrated database retrieval system