KEGG   ENZYME: 4.3.1.2
Entry
EC 4.3.1.2                  Enzyme                                 
Name
methylaspartate ammonia-lyase;
beta-methylaspartase;
3-methylaspartase;
L-threo-3-methylaspartate ammonia-lyase
Class
Lyases;
Carbon-nitrogen lyases;
Ammonia-lyases
Sysname
L-threo-3-methylaspartate ammonia-lyase (mesaconate-forming)
Reaction(IUBMB)
L-threo-3-methylaspartate = mesaconate + NH3 [RN:R03696]
Reaction(KEGG)
R03696
Substrate
L-threo-3-methylaspartate [CPD:C03618]
Product
mesaconate [CPD:C01732];
NH3 [CPD:C00014]
Comment
A cobalamin protein.
History
EC 4.3.1.2 created 1961
Pathway
ec00630  Glyoxylate and dicarboxylate metabolism
ec00660  C5-Branched dibasic acid metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K04835  methylaspartate ammonia-lyase
Genes
AFMAFUA_3G00790
NFINFIA_001410
AORAO090010000710
AFVAFLA_014211
ACHEACHE_70014S
PDPPDIP_33520
ECEZ0892
ECSECs_0761
ECFECH74115_0829
ETWECSP_0779
ELXCDCO157_0741
ECOOECRM13514_0750
ECOHECRM13516_0697
EOKG2583_0892
ELRECO55CA74_04340
ECMEcSMS35_0749
EUMECUMN_0814
ECTECIAI39_0701
EOCCE10_0730
ELOEC042_0753
EFEEFER_2378
EMAC1192_08695
ESZFEM44_18110
SESSARI_02201
SDYSDY_0673
SDZAsd1617_00848
ESHC1N69_07900
KOXKOX_14665
KOEA225_1756
KOYJ415_22870
KOMHR38_13440
KOKKONIH1_08640
KOCAB185_27495
KLLBJF97_09010
KLWDA718_19620
KGRJJJ10_19550
CKOCKO_02419
CFDCFNIH1_13770
CBRAA6J81_09350
CWECO701_15165
CYOCD187_16565
CPOTFOB25_04015
CFQC2U38_07700
CSEDJY391_14750
CAMAF384_03285
CAFAL524_19000
CIFAL515_08250
CFARCI104_08015
CIRC2U53_17235
CIEAN232_22705
CPARCUC49_03400
CTELGBC03_21985
CITZE4Z61_09960
CARSE1B03_08815
ESCEntcl_1732
KLEAO703_13285
BUFD8682_20785
BFTMNO13_05010
YREHEC60_20895
YENYE4043
YEPYE105_C3763
YEYY11_31521
YELLC20_00182
YEWCH47_3688
YETCH48_1495
YEFFORC2_0151
YEEYE5303_38771
YALAT01_1098
YINCH53_313
YROCH64_1340
YHID5F51_21360
YCAF0T03_21045
MMKMU9_1023
HAVAT03_08650
OPODSM2777_13860
PPULRO07_15990
BPEBP0806 BP3177
BPCBPTD_0804 BPTD_3139
BPERBN118_0709
BPETB1917_0643 B1917_2973
BPEUQ425_31590 Q425_7420
BPARBN117_3385 BN117_3938
BPABPP3422 BPP3864
BBHBN112_4085 BN112_4543
BBRBB3872 BB4337
BBMBN115_3544 BN115_4013
BBXBBS798_3652 BBS798_4114
BFZBAU07_20575
BOHAKI39_19475
BGMCAL15_20690
XYKGT347_12540
MLOmlr6095
MLNA9174_31760
MCIMesci_5690
MOPMesop_6269
MAMMesau_05741
MAMOA6B35_31635 A6B35_31710
MESWA9K65_030880
MESMEJ066_12585
MJREB229_32430
MERDEB233_30065
BICLMTR13_26000
PPANESD82_15275
GFUKM031_18930
ALHG6N82_05195
ELQGa0102493_112996
CTCCTC_02563
CTETBN906_02814
CLJCLJU_c40610
CAHCAETHG_1904
CSQCSCA_4328
CACECACET_c34410
CCKCcar_17555 Ccar_19615
CEUA7L45_08020
CFMBJL90_02575
CARGRSJ17_03855
CDRKB9W14_23400
CCOHSAMEA4530647_2259
CLOSDMR38_20135
CCAAKQH81_15280
AMTAmet_3414
HHWNCTC503_02397
CALEFDN13_04640
BYLA4V09_10270
BHANCGC63_11295
BPROPMF13cell1_03217
EACEAL2_808p05890
TEMJW646_17970
TGCL0P85_10055
PBQC3V37_01025
DSYDSY3233
DHDDhaf_4400
DDHDesde_3779
DMTDESME_13810
DORDesor_5275
DAIDesaci_4373
DMIDesmer_4259
DCADesca_0604
DRMDred_2689
DRUDesru_0927
DFGB0537_13815
FWADCMF_09590
AACXDEACI_0128
VGUHYG85_02135
VPYHZI73_09950
ACAEHYG86_02375
CTHMCFE_0619
FMSM1R53_04075
EUUADJ67_05945
CHYCHY_0484 CHY_0582
TPZTph_c20250
TEPTepRe1_0115
TAETepiRe1_0120
HORHore_15430
HPKHprae_1850
HALSD7D81_15595
IFNGM661_12735
AARAcear_0480
HHLHalha_1649
AFTBBF96_08380
ECOUM1R54_02150
PUFUFO1_3073
PFTJBW_01516
MANAMAMMFC1_00632
STEDSPTER_10690
MANRMPAN_001680
MBJKQ51_00879
XCLG4Z02_00740
TBMBK010_00845
TBZBK011_00735
TBKHF295_06620
MSEDE3O41_00265
FRPAX769_17710
NMESH9L09_01760
MMARMODMU_4014
KALKALB_5717
MTUACSH63_31865
BSOLFSW04_00285
ABAOBEQ56_05600
TDETDE_2235
TPITREPR_1304
TPEDTPE_1176
TPKJO40_01075
SCDSpica_1659
FVAFV113G1_25160
FULC4N20_01145
FMOC4N19_13190
IPOIlyop_0556
CSOMMKD34_06450
CPORBED41_14050
PAHPoras_1170
PCRENCTC12858_01580
PSOECE91St14_10350
PETPEIBARAKI_4288
PROJKDN43_05785
TOHBCB71_00035
PITPIN17_0467
PNIJ5A59_01360
DTHDICTH_1229
DTUDtur_1344
HALVNG_2289G(mal)
HSLOE_4207F(mal)
HAGSJT689_10590
HABOJRZ79_08965
HANRLJ422_09240
HALXM0R89_18080
SALIL593_04670
HMArrnAC0687(mal)
HHIHAH_1339(mal)
HHNHISP_06855
HABSG26_14700
HTABVU17_06525
HALJG9465_08575
HSINKDQ40_06775
HMUHmuk_2982
HALZE5139_02185
HALLLC1Hm_2319(mal)
HAZPGBQ70_02185
HRRHZS55_19995
HPELHZS54_23495
HGIABY42_16395
HTUHtur_1592
HDABB347_04020
HSALJMJ58_00675
HLOJ0X27_02305
HAKZJ0X25_14770
NMGNmag_3336(mal)
HXAHalxa_3157
NATNJ7G_3291
NPENatpe_2592
NVRFEJ81_11890
NPLFGF80_10930
NAYHYG81_14700
HALYHYG82_17320
HJTDVR14_02945
NGENatgr_2182 Natgr_3386
HRUHalru_1550
NOUNatoc_1511
HLRHALLA_00800 HALLA_10845
HLCCHINAEXTREME16085
NAJB1756_12015
NAGAArcMg_1647
NANAArc1_1992
NBGDV706_12990
NASGCU68_13735
SAWLNGM29_08780
 » show all
Reference
1  [PMID:13618029]
  Authors
BARKER HA, SMYTH RD, WAWSZKIEWICZ EJ, LEE MN, WILSON RM.
  Title
Enzymic preparation and characterization of an alpha-L-beta-methylaspartic acid.
  Journal
Arch Biochem Biophys 78:468-76 (1958)
DOI:10.1016/0003-9861(58)90371-0
Reference
2
  Authors
Bright, H.J. and Ingraham, L.L.
  Title
The preparation of crystalline beta-methylaspartase.
  Journal
Biochim Biophys Acta 44:586-588 (1960)
Other DBs
ExplorEnz - The Enzyme Database: 4.3.1.2
IUBMB Enzyme Nomenclature: 4.3.1.2
ExPASy - ENZYME nomenclature database: 4.3.1.2
BRENDA, the Enzyme Database: 4.3.1.2
CAS: 9033-26-5
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