| Entry |
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| Name |
dichloromethane dehalogenase;
dichloromethane chloride-lyase (chloride-hydrolysing)
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| Class |
Lyases;
Carbon-halide lyases;
Carbon-halide lyases (only sub-subclass identified to date)
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| Sysname |
dichloromethane chloride-lyase (adding H2O; chloride-hydrolysing; formaldehyde-forming)
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| Reaction(IUBMB) |
dichloromethane + H2O = formaldehyde + 2 chloride [RN: R00603]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
Requires glutathione.
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| History |
EC 4.5.1.3 created 1989
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| Pathway |
| ec00625 | Chloroalkane and chloroalkene degradation |
| ec01120 | Microbial metabolism in diverse environments |
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| Orthology |
| K17070 | dichloromethane dehalogenase |
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| Genes |
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| Reference |
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| Authors |
Kohler-Staub D, Leisinger T. |
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| Title |
Dichloromethane dehalogenase of Hyphomicrobium sp. strain DM2. |
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| Journal |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 4.5.1.3 |
| ExPASy - ENZYME nomenclature database: | 4.5.1.3 |
| UM-BBD (Biocatalysis/Biodegradation Database): | 4.5.1.3 |
| BRENDA, the Enzyme Database: | 4.5.1.3 |
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| LinkDB |
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