KEGG   ENZYME: 5.1.3.10
Entry
EC 5.1.3.10                 Enzyme                                 
Name
CDP-paratose 2-epimerase;
CDP-paratose epimerase;
cytidine diphosphoabequose epimerase;
cytidine diphosphodideoxyglucose epimerase;
cytidine diphosphoparatose epimerase;
cytidine diphosphate paratose-2-epimerase;
CDP-abequose epimerase (incorrect);
CDP-D-abequose 2-epimerase (incorrect);
CDP-tyvelose 2-epimerase,
Class
Isomerases;
Racemases and epimerases;
Acting on carbohydrates and derivatives
Sysname
CDP-3,6-dideoxy-D-glucose 2-epimerase
Reaction(IUBMB)
CDP-alpha-D-paratose = CDP-alpha-D-tyvelose [RN:R04266]
Reaction(KEGG)
R04266
Substrate
CDP-alpha-D-paratose [CPD:C03598]
Product
CDP-alpha-D-tyvelose [CPD:C03599]
Comment
Requires NAD+.
History
EC 5.1.3.10 created 1972, modified 2005
Pathway
ec00520  Amino sugar and nucleotide sugar metabolism
ec00541  O-Antigen nucleotide sugar biosynthesis
ec01100  Metabolic pathways
Orthology
K12454  CDP-paratose 2-epimerase
Genes
STYSTY2298(rfbE)
STTt0784(rfbE)
SEXSTBHUCCB_8360
SENTTY21A_03975
SPTSPA0778(rfbE)
SEKSSPA0732(rfbE)
SEDSeD_A2428
SEGSG2119
SELSPUL_0809(rfbE)
SEGASPUCDC_0809(rfbE)
SETSEN2085C(rfbE)
SENAAU38_10535
SENOAU37_10545
SENVAU39_10545
SENQAU40_11800
SENLIY59_10830
SENJCFSAN001992_00985
SEEPI137_03635
YMOHRD69_10875
FSMCCS41_13935
XBUHGO23_18935
LSOLGOY17_06235
TCNH9L16_11300
SDKKHX94_02795
APELCA267_007245
PINPing_0777
LCDclem_00985(rfbE)
LJRNCTC11533_02025(rmlB_2)
MMAIsS8_4814
AFRIE3E15_05595
TIGTHII_1699
BLEPAL038_14615
NWRE3U44_15405
BSTGWT74_16865
VPEVarpa_3055
RTARta_16030
MIUABE85_08525
GCAGalf_2844
SULCCVO_08540
CCOCCCON33237_0123
HYONNO_0327
GEMGM21_2537
GEFFO488_01050
GURGura_3786
GEOGeob_2128(tyv) Geob_3241
GBMGbem_0859(tyv) Gbem_1684
GBNGEOBRER4_24780
GERKP004_11765
GSUBKP001_03400
DMADMR_38130 DMR_38140
DCBC3Y92_03590 C3Y92_03595
DAFDesaf_1146 Desaf_1351
DEJAWY79_10410
DOLDole_0520
DALKDSCA_06670
ADEAdeh_1061 Adeh_4298
ACPA2cp1_1189
AFWAnae109_3217
ANKAnaeK_1120
MXAMXAN_1639(rfbE)
CCXCOCOR_01687(rfbE)
MFULILAB_00525
MMASMYMAC_001762
AVMJQX13_06785 JQX13_36685 JQX13_36690
MBDMEBOL_002337
CFUSCYFUS_003878 CYFUS_003879 CYFUS_009178
SCLsce6772 sce8935(galE6)
SCUSCE1572_39725 SCE1572_51015
PAUUE8A73_002600
SAMYDB32_001205
MRMA7982_02004 A7982_05838
DTIDesti_4499
PCAYFRD00_19535
GAGGGromo_00455
MCIMesci_5445
MOPMesop_6535
MAMMesau_05466
MESWA9K65_029705
MESMeso_2779
SMESM_b20244(tyv_OR_Smb20244)
SMKSinme_3929
SMQSinmeB_4426
SMXSM11_pD1367(tyv)
SMIBN406_06422(tyv)
SMEGC770_GR4pD1353
SMELSM2011_b20244(tyv)
SMERDU99_32150
SMDSmed_3888
SFDUSDA257_c51200(rfbE)
SAMESAMCFNEI73_Ch3083(rfbE)
SINOSS05631_c31260
ESJSJ05684_b50780
EAKEKH55_5090
EMXFKV68_26800
RETRHE_PB00053
RECRHECIAT_PC0000295
RELREMIM1_PA00060
REPIE4803_PD00366
REIIE4771_PE00381
RLGRleg_5580
RLBRLEG3_32965
RIRBN877_II1875
RGARGR602_CH03301
RHNAMJ98_PE00169
RPHAAMC79_PD00317
RHXAMK02_PA00054
RHVBA939_16960
RHKKim5_PD00342
REZAMJ99_PD00170
RHRCKA34_26800
RADCO657_35595
RHIDFFM81_026115
RLNJ0663_04755
RBANJ2J98_29640
NEOCYG48_05775
RHTNT26_1836
RFVRFYW14_01915
PDESFE840_004970
BRABRADO2068
BRCBCCGELA001_15165
BRADBF49_5295
BROBRAD285_5204(rfbE)
BGQX265_08410
BVZBRAD3257_5348(rfbE)
MEAMex_1p0147
MDIMETDI0135
MEXMext_0250 Mext_0510
MCHMchl_0196
MPOMpop_1270
MRDMrad2831_1321
METM446_2077
MNOMnod_0433
MEEDA075_12925
METDC0214_05555
METIDK427_15050
MMESMMSR116_02500
MTEADK419_19920
MOGMMB17_00070
MICOGDR74_16155
BBARRHAL1_03203(rfbE)
CHELAL346_19520
FILBN1229_v1_1399(rfbE)
FIYBN1229_v1_1398(rfbE)
MSCBN69_3019
PLEOOHA_1_01494(rfbE)
MLUTJET14_08455
AUBLXB15_13680
LABPFJ695_11020
LIZLGH83_12840
PZUPHZ_c2088
BRDJL11_07055
CIDP73_4351
CONTQ29_02260
RSPRSP_0519
RSHRsph17029_2171 Rsph17029_3699
RSQRsph17025_2430
RSKRSKD131_1853 RSKD131_4168
CAZTLV780_11085
PYEA6J80_20395
PCONB0A89_13525
PARUCYR75_13150
PLIAE4191_16710
SPANAWL63_22120
SPIIG7077_06375
SARIH5J25_14620
SJPSJA_C1-11160(rfbB)
SINBSIDU_08660
SYBTZ53_21575
SPMIK663_04900
SUFLFIL70_10755
SBARH5V43_08490
SPHJBSL82_06095
SPHSETR14_09865
ALBAEB_P1943
ROSCTJ15_01330
RMTIAI58_17285
LCKHN018_16770
SHUMSTHU_14620 STHU_14630
SVCSTVA_38620 STVA_38630
STELSTAQ_11090 STAQ_11100
ALIAZOLI_p50348(rfbE)
ABSAZOBR_p210161 AZOBR_p210164 AZOBR_p60050 AZOBR_p60051
ABQABAZ39_23815 ABAZ39_23830
ABFAMK58_22015 AMK58_22030 AMK58_29225 AMK58_29230
AZTTSH58p_02840 TSH58p_02855 TSH58p_18140 TSH58p_18145
AZMDM194_24705
AZZDEW08_18670
AOZHUE56_00345
SKTIGS68_07555 IGS68_17820 IGS68_17830
SMUCJL100_008180 JL100_008190 JL100_020065
SROEJL101_008065 JL101_008075 JL101_018810
RCERC1_0527(rfbE)
MAGamb3785 amb3786
MAGXXM1_1573 XM1_1574
MAGNWV31_15880 WV31_15885
TMOTMO_a0325(rfbE)
MGMMmc1_2871 Mmc1_2872
APCHIMB59_00014910
BMXBMS_0380(rfbE)
PBKBack11_31800
PALOE6C60_1121
COHEAV92_06975
CCECcel_0969
DGIDesgi_4708
MCOOMCOO_26540(rfbE)
APRECNX65_14865
AMIAmir_2951
SSYIEKG83_14875 EKG83_31880
STPStrop_0041
SAQSare_0046
MAUMicau_0093
MILML5_0076
MICBMicB006_0084
MTUACSH63_25580
MICHFJK98_00360
MTEMGCE86_25930
MCABHXZ27_00290
MSAGGCM10017556_26630
VMAVAB18032_04800
MCRAID554_14110
ASEACPL_6844
AMSAMIS_65950
ACTNL083_0049
AFSAFR_00260
ACTSACWT_6714
AIHAiant_26720
PLKCIK06_00430
PLABC6361_17250
PLATC6W10_34340
VERHUT12_00325
ATLAthai_57920
ASERAsera_17100
PRYPrubr_24400
CATICS0771_12420
DVCDvina_00260
NHYJQS43_25535
SNASnas_0259
BSOLFSW04_00720
AYMYM304_22180
ATQGH723_12350
IAMHC251_08360
SYJD082_21370
SYNESyn6312_0747
CGCCyagr_1211 Cyagr_2189
CYICBM981_2621(rfbE)
PMMPMM1201
AMRAM1_G0129
LBOLBWT_55510
LSKJ5X98_02940 J5X98_02950
HHGXM38_013790
PSEUPse7367_3618 Pse7367_3619
GENGM3709_1319 GM3709_1323
CHONNIES4102_32980 NIES4102_38220
MARMAE_46390 MAE_46430
MPKVL20_5994 VL20_5997
MIQB5D77_24475 B5D77_24485
MVZmyaer102_20070 myaer102_20100
CWACwatDRAFT_3477
CYJCyan7822_3234 Cyan7822_3235
CYNCyan7425_0420 Cyan7425_0423 Cyan7425_1267
ARPNIES39_A00610
OXYHCG48_13540
MVAGD0A34_13385 D0A34_22230
MICMic7113_2162
ONIOsc7112_0103 Osc7112_4264
PHORJWS08_07235 JWS08_07245
GVIglr1179
GLJGKIL_1591(rfbE) GKIL_4274
GMLISF26_01285
AVAAva_3352 Ava_3353
ANBANA_C13063
AWAAA650_04425
ANNEH233_06480 EH233_06485
CALOCal7507_0376
NSPBMF81_04458(rfbE) BMF81_04459(rfbE_2)
DOUBMF77_03076(rfbE_1) BMF77_03080(rfbE_2)
CCURIAR63_02080 IAR63_16530 IAR63_17095
AFLOHEQ12_06735
TOQHCG51_15615 HCG51_15620 HCG51_15705 HCG51_15720
NCNBZZ01_04690 BZZ01_26920
CTHEChro_1106 Chro_1109 Chro_2364 Chro_4810
SCSSta7437_1461
STANSTA3757_40270
CAUCaur_1745
CHLChy400_1889
CAGCagg_1989 Cagg_2762
PSUBPelsub_P1573
ABAOBEQ56_06695
CAPCLDAP_10430 CLDAP_10460(galE)
PBFCFX0092_A1594(rfbE)
THUGKNN16_14140
DGEDgeo_2646
TTSThthe16_0979
CCZCCALI_02423
FGIOP10G_3322
OTEOter_3986 Oter_3990
OBGVerru16b_02012(rfbE_1) Verru16b_02015(rfbE_2)
OLEK0B96_03860 K0B96_04545
RUFIK0V07_03675
ROOG5S37_01135 G5S37_26580
VBAIMCC26134_03185 IMCC26134_08260 IMCC26134_11905
RBARB7482(rfbE) RB8904(tyv)
RULUC8_39750(rfbE)
RMLFF011L_41660(rfbE)
MFFMFFC18_31990(rfbE)
ROLCA51_25980(rfbE)
RLCK227x_00290(rfbE_1) K227x_06680(rfbE_2)
LPAVPLANPX_2619
AMUCPan181_22850(rfbE)
AMOBHG15A2_22890(rfbE)
FMRFuma_05606(rfbE_1) Fuma_05609(rfbE_2)
GMRGmarT_46430(rfbE_1) GmarT_46450(rfbE_2)
IPAIsop_1615 Isop_3763
SACISinac_3894
BROCIPI25_09915 IPI25_09920
PHMPSMK_00110
VAIBU251_04330
LBJLBJ_0629
LBLLBL_2450
LBILEPBI_II0120
LBFLBF_4117
LSTLSS_06934
LAJA0128_02855
LMAYDPV73_08855
LKMEFP84_13685
LWLFHG68_03500
LKBLPTSP3_g20880 LPTSP3_g20890 LPTSP3_g37840
TPXTurpa_0300 Turpa_0302
ABAAcid345_3495
TSAAciPR4_1873
TRSTerro_1884
ABASACPOL_5365
SUSAcid_0286 Acid_0287 Acid_3011
PFERIRI77_14595 IRI77_14600
CTMCabther_A1238 Cabther_B0600 Cabther_B0601
CVLJ8C06_14820 J8C06_14825
CHLOJ8C02_06010 J8C02_11605 J8C02_11610
ABACLuPra_04958(rfbE_1) LuPra_04961(rfbE_2)
EPOEpro_0330(rfbE)
BFSBF9343_2519(rfbE)
BFGBF638R_3482
BFBVU15_06465 VU15_11510 VU15_16410
BEGINE88_03490(rfbE)
PPNPalpr_0967
DRCG0Q07_02770
RMRRmar_1136
RMGRhom172_1666
FLSGLV81_17870
LACSH4075_02055 H4075_02060
PEJFYC62_06320
MUPA0256_22850
MGIKGO620_005205
SLISlin_2975 Slin_5183 Slin_6291 Slin_6411
SRDSD10_15860 SD10_21310 SD10_26090
SMONAWR27_00255 AWR27_21185
SPIRCWM47_14810 CWM47_25525
SPIKEXU85_09755 EXU85_33055
SPIBG8759_02995 G8759_17885
STAEHNV11_04440 HNV11_22280
SRHOHH216_09195 HH216_18240 HH216_20235
PSEZHME7025_00129(rfbB) HME7025_00130(rfbE)
RHOZGXP67_10895
DFEDfer_3530 Dfer_4399 Dfer_4599
DSNHWI92_04920 HWI92_15785 HWI92_18725
RSIRunsl_1529 Runsl_2293
RUNDR864_16535 DR864_19785
RUPDTQ70_20665 DTQ70_25350
EOLEmtol_1550 Emtol_2529
FAEFAES_0743 FAES_1099
FIBA6C57_10135 A6C57_10505
ALSDJ013_05925 DJ013_07450
HNVDDQ68_04535 DDQ68_04540
HYJFHG12_18385
PKOPKOR_00265
PACTCA264_12140
RTIDC20_03940
ADDHUW48_14705
FBTD770_00415
FPALHYN49_06960
FMGHYN48_06610
COCCoch_0704
CAPNCBG49_03905
MARXINR76_03925 INR76_03930
FTEFluta_0213
BBAUAEM51_03690
SAFSULAZ_1208
PMXPERMA_1997
OCYOSSY52_03590(rfbE)
TYETHEYE_A0473 THEYE_A0474
NDENIDE2875(rfbE)
MAEMaeo_0389
MBNMboo_1767 Mboo_1768
HDLHALDL1_10980
HBOHbor_17010
HRMK6T25_01940
HRUHalru_1015
SALIL593_04980
SACDHS1genome_1891
PSYTDSAG12_01820
AGWQT03_C0001G0544
 » show all
Reference
1  [PMID:5924649]
  Authors
Matsuhashi S.
  Title
Enzymatic synthesis of cytidine diphosphate 3,6-dideoxyhexoses. II. Reversible 2-epimerization of cytidine diphosphate paratose.
  Journal
J Biol Chem 241:4275-82 (1966)
Reference
2  [PMID:7826006]
  Authors
Liu HW, Thorson JS.
  Title
Pathways and mechanisms in the biogenesis of novel deoxysugars by bacteria.
  Journal
Annu Rev Microbiol 48:223-56 (1994)
DOI:10.1146/annurev.mi.48.100194.001255
Reference
3  [PMID:12642575]
  Authors
Koropatkin NM, Liu HW, Holden HM
  Title
High resolution x-ray structure of tyvelose epimerase from Salmonella typhi.
  Journal
J Biol Chem 278:20874-81 (2003)
DOI:10.1074/jbc.M301948200
  Sequence
[sty:STY2298]
Other DBs
ExplorEnz - The Enzyme Database: 5.1.3.10
IUBMB Enzyme Nomenclature: 5.1.3.10
ExPASy - ENZYME nomenclature database: 5.1.3.10
BRENDA, the Enzyme Database: 5.1.3.10
CAS: 37318-36-8
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