KEGG   ENZYME: 5.3.3.3
Entry
EC 5.3.3.3                  Enzyme                                 
Name
vinylacetyl-CoA Delta-isomerase;
vinylacetyl coenzyme A Delta-isomerase;
vinylacetyl coenzyme A isomerase;
Delta3-cis-Delta2-trans-enoyl-CoA isomerase
Class
Isomerases;
Intramolecular oxidoreductases;
Transposing C=C bonds
Sysname
vinylacetyl-CoA Delta3-Delta2-isomerase
Reaction(IUBMB)
vinylacetyl-CoA = (E)-but-2-enoyl-CoA [RN:R03031]
Reaction(KEGG)
R03031
Substrate
vinylacetyl-CoA [CPD:C02331]
Product
(E)-but-2-enoyl-CoA [CPD:C00877]
Comment
Also acts on 3-methyl-vinylacetyl-CoA.
History
EC 5.3.3.3 created 1961, modified 2011
Pathway
ec00650  Butanoate metabolism
ec01100  Metabolic pathways
Orthology
K14534  4-hydroxybutyryl-CoA dehydratase / vinylacetyl-CoA-Delta-isomerase
Genes
BGJAWC36_04165
BIZHC231_14560
AFUSEYZ66_08275
NAXHC341_03525
KAKKalk_18475
MGEOCFI10_04675
PNUPnuc_0370
ACHRC2U31_22605
RHFEUB48_11505
POSDT070_18255
POOF7R28_12325
VPEVarpa_3723
VPDVAPA_1c23470
VAAAX767_00840
VBOCKY39_20160
VAMC4F17_02945
COFFOZ74_14275
RTARta_18760
HYBQ5W_11860
DIHG7047_12160
DRGH9K76_11775
SIMPC6571_16860
MELAC6568_04615
MPTMpe_A2516
METPC1M51_16160
GLCJQN73_05375
LCHLcho_2993
METRBSY238_78
APPCAP2UW1_1984
GMEGmet_2215
DEUDBW_0157(abfD)
DOLDole_2592
DALDalk_0576 Dalk_1215 Dalk_2536 Dalk_2731 Dalk_3391
DTOTOL2_C28460(hpaB)
DWDDSCW_05650(abfD_1) DSCW_20400 DSCW_31010(abfD_2) DSCW_33530 DSCW_58950 DSCW_59050
DALKDSCA_29960(abfD)
DMMdnm_056620
DEKDSLASN_12450(abfD)
SAMYDB32_005276
SATSYN_02445
DTIDesti_0809 Desti_1603 Desti_2004 Desti_3009 Desti_3036
SFUSfum_3141 Sfum_3932
DBRDeba_0626 Deba_1051
DAVDESACE_06790
BRKCWS35_16070 CWS35_35405
BELBE61_32540
BSEPHAP48_0025570
BQBJ4P68_0010490
OCAOCAR_6245
OCGOCA5_c17860(hbaB)
OCOOCA4_c17860(hbaB)
VGOGJW-30_1_00655(abfD)
BOIBLM15_19040
RHZRHPLAN_22730
RBMTEF_19955
PSTGE8M01_28340
RIDRIdsm_00769(abfD)
NOGGKE62_06270
SMAGAN936_12040
SMAZLH19_13280
SPHQBWQ93_08330
RDICMV14_07515
SPHAD3Y57_03405
SJPSJA_C2-03820
SINBSIDU_11465
SPHJBSL82_04790
SRFLHU95_19065
DEXHWD60_00500
DVNHQ394_03595
BACOOXB_3219
EFFskT53_09470
CBECbei_2100
CBZCbs_2100
CBEILF65_02412
CKLCKL_3020(abfD)
CKRCKR_2668
CLSCXIVA_14640
CPASClopa_4009
CSQCSCA_3616 CSCA_3622
CCKCcar_01580
CTYKCTK_C07640(abfD)
CEUA7L45_11985
CDRKB9W14_01580
CDYF3K33_10480
CFERD4Z93_08285 D4Z93_11490
CCAAKQH81_12640
CRSFQB35_09340
CPRFK7H06_04670 K7H06_04690
FPLAA4U99_00480
CAPREQM14_06625 EQM14_09375 EQM14_10020
OVAOBV_01110(abfD) OBV_03760(abfD) OBV_28840(abfD) OBV_33370(abfD) OBV_35330(abfD) OBV_40730(abfD)
OBJEIO64_09505
VFAMM35RIKEN_12830(abfD)
BPROPMF13cell1_01502(abfD)
LACYA4V08_31375
ARFAR1Y2_2847 AR1Y2_3067
ACACEYQ97_04915
WHJH9Q79_06930 H9Q79_08895 H9Q79_10120
CDFCD630_23410(abfD)
PDCCDIF630_02580(abfD)
CDCCD196_2184(abfD)
CDLCDR20291_2230(abfD)
PDFCD630DERM_23410(abfD)
SLPSlip_0662
DSYDSY4732
DDHDesde_1768
DMTDESME_04405
DORDesor_0848 Desor_0856 Desor_0867 Desor_2541 Desor_3713
DAIDesaci_1066 Desaci_1680
DMIDesmer_0870 Desmer_3350
PTHPTH_1222 PTH_1770
TFRBR63_00565 BR63_09495 BR63_10065 BR63_10755 BR63_16155 BR63_17815 BR63_17890
FWADCMF_17520 DCMF_19260 DCMF_24550 DCMF_27885
AACXDEACI_0207 DEACI_1870
ELMELI_0281
EMTCPZ25_012290
ELIMB2M23_04455
CMIUB1H56_01400 B1H56_13815
IBUIB211_00283 IB211_01887c
AMIJEQM06_00080 EQM06_05020
ABUTAmi103574_00850
ETMCE91St48_13840(abfD_1) CE91St48_25600(abfD_2) CE91St48_30890 CE91St48_33910(abfD_3)
CHYCHY_1314(abfD) CHY_1730
PEDING2D1G_1210(abfD)
SPOAEQM13_05475
MEDMELS_0342
MHWACT01_02930 ACT01_03000 ACT01_03330 ACT01_05095 ACT01_09475
MEGDKB62_02945 DKB62_07650
STEDSPTER_02600(abfD)
AINAcin_2034
MIDMIP_03610
MCHIAN480_13630
MMALCKJ54_11700
MDXBTO20_21570
ROAPd630_LPD17032
RGOKYT97_22845
GPOGPOL_c49520
GTABCM27_04235
GAMGII34_07415
SLEsle_61260(sle_61260)
SFEUIM697_23390
NANOG5V58_14050
TCUTcur_0955
MCRAID554_30515
VERHUT12_14055
DVCDvina_12895
ERZER308_02395
TRMJO41_12025
TRZGWP43_07785
TMEDDWB79_09475
FNCHMPREF0946_00150
FNTHMPREF0405_01111
FVAFV113G1_21520
FULC4N20_16050
FNFBSQ88_08665
FCII6I83_08420
PGIPG_0692(abfD)
PGNPGN_0727
PGTPGTDC60_1817(abfD)
PAHPoras_0448
PCRENCTC12858_01801(abfD)
PCAGNCTC12856_01249(abfD)
PENDLA319_00265
PSOECE91St14_12610(abfD)
TFOBFO_1484(abfD)
OSPOdosp_2062
BUYD8S85_11120
BVIRI6J59_04675
RSIRunsl_1400
RUNDR864_15875
SHYRLA303_00675
TTKTST_0398(abfD)
AFUAF_0333 AF_1027
AFGAFULGI_00003320 AFULGI_00011230
ASTAsulf_01733
FPLFerp_0911
GACGACE_0594 GACE_1499
GAHGAH_01688
FACFACI_IFERC01G0375
FAIFAD_1294
IHOIgni_0595
IISEYM_00450
PFMPyrfu_1275
STOSTK_00630 STK_16590
SOHD1869_09350 D1869_14735
SSOSSO2503(abfD-1) SSO2738(abfD-2)
SOLSsol_0312 Ssol_0550
SSOASULA_0305 SULA_0541
SSOLSULB_0307 SULB_0543
SSOFSULC_0305 SULC_0541
SSHIJ5U23_00761 J5U23_01288
SCASSACC_14040 SACC_17730 SACC_24830
SAISaci_1103 Saci_2143(abfD)
SACNSacN8_05365 SacN8_10430
SACRSacRon12I_05355 SacRon12I_10685
SACSSUSAZ_05145 SUSAZ_09780
SISLS215_0322 LS215_2744
SIAM1425_0293 M1425_2585
SIMM1627_0293 M1627_2638
SIDM164_0311 M164_2569
SIYYG5714_0299 YG5714_2751
SINYN1551_0139 YN1551_2902
SIILD85_0299 LD85_2896
SIHSiH_0300 SiH_2522
SIRSiRe_0298 SiRe_2362
SICSiL_0284 SiL_2419
SULABFU36_06625 BFU36_11260
SULEGFS03_00420 GFS03_03030
SULOGFS33_05550 GFS33_08205
SULLEWF20_01055 EWF20_10955
MSEMsed_1220 Msed_1321
MCNMcup_0888
MHKDFR87_12060
MPRUDFR88_00405 DFR88_11715
MTENGWK48_00525 GWK48_10830
MJNMjAS7_2228 MjAS7_2390
AHOAhos_2036
AMANB6F84_01555 B6F84_05320
ABRIDFR85_01140 DFR85_12315
ASULDFR86_01545
AAMBD1866_05205
ACIHHS5_08570
SAZOD1868_09500
CSTYKN1_05100
STEPIC006_0828
PAIPAE2693
PISPisl_0248
PCLPcal_1396
PYRP186_0718
POGPogu_1298
TNETneu_0422
PYWPYWP30_00440
TTNTTX_1102
TUZTUZN_0949
VDIVdis_2214
VMOVMUT_0681 VMUT_2253
CLGCalag_0024
NMRNmar_0207
NIRNSED_00835
NKRNKOR_00855
NIDNPIRD3C_0596(abfD)
NINNADRNF5_2050(abfD)
NIWNisw_03935
NCLC5F47_01015
NOXC5F49_01000
NUEC5F50_01330
NIPNsoK4_07890
NCTNMSP_1505
NICDSQ20_01275
CSYCENSYa_0022
NGANgar_c34390
NVNNVIE_017160
NEVNTE_00645
TAANMY3_03315(abfD)
NFNNFRAN_0724(hcd)
NCVNCAV_0126 NCAV_0127
NBVT478_1248(abfD)
TAHSU86_007675
NIUDSQ19_09180
NDVNDEV_0181(hcd)
BARCAOA65_2031 AOA65_2222
LOKILokiarch_00630(abfD_1) Lokiarch_26350(abfD_2)
 » show all
Reference
1
  Authors
Lynen, F., Knappe, J., Lorch, E., Jutting, G. and Ringelmann, E.
  Title
Die biochemische Funktion des Biotins.
  Journal
Angew Chem 71:481-486 (1959)
Reference
2  [PMID:13741692]
  Authors
RILLING HC, COON MJ.
  Title
The enzymatic isomerization of alpha-methylvinylacetyl coenzyme A and the specificity of a bacterial alpha-methylcrotonyl coenzyme A carboxylase.
  Journal
J Biol Chem 235:3087-92 (1960)
Other DBs
ExplorEnz - The Enzyme Database: 5.3.3.3
IUBMB Enzyme Nomenclature: 5.3.3.3
ExPASy - ENZYME nomenclature database: 5.3.3.3
BRENDA, the Enzyme Database: 5.3.3.3
CAS: 9023-73-8
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