KEGG ENZYME: 5.4.2.13

ENZYME: 5.4.2.13

Entry

EC 5.4.2.13                 Enzyme

Name

phosphogalactosamine mutase;
ST0242 (locus name)

Class

Isomerases;
Intramolecular transferases;
Phosphotransferases (phosphomutases)

Sysname

alpha-D-galactosamine 1,6-phosphomutase

Reaction(IUBMB)

D-galactosamine 6-phosphate = alpha-D-galactosamine-1-phosphate [RN:R12221]

Reaction(KEGG)

R12221

Substrate

D-galactosamine 6-phosphate [CPD:C06377]

Product

alpha-D-galactosamine-1-phosphate [CPD:C22029]

Comment

The enzyme, characterized from the archaeon Sulfolobus tokodaii, is also active toward D-glucosamine 6-phosphate (cf. EC 5.4.2.10, phosphoglucosamine mutase).

History

EC 5.4.2.13 created 2018

Pathway

ec00520

Amino sugar and nucleotide sugar metabolism

ec01100

Metabolic pathways

Orthology

K28126

phosphogalactosamine/phosphoglucosamine mutase

Genes

TCS:	IMZ38_06595(glmM)

STO:

STK_02420

SOH:	D1869_00715(glmM)

SJV:	SJAV_12100(glmM)

SSO:	SSO0207(pmM)

SOL:

Ssol_1188

SSOA:

SULA_1224(glmM)

SSOL:

SULB_1225(glmM)

SSOF:

SULC_1223(glmM)

SSHI:

J5U23_00050

SCAS:

SACC_01230

SIS:	LS215_2090

SIA:	M1425_1927

SIM:	M1627_2005

SID:

M164_1935

SIY:	YG5714_2049

SIN:	YN1551_0869

SII:

LD85_2187

SIH:

SiH_1872

SIR:

SiRe_1800

SIC:

SiL_1781

SULA:

BFU36_04880

SULE:

GFS03_10580(glmM)

SAI:

Saci_0806

SACN:

SacN8_03910

SACR:

SacRon12I_03900

SACS:

SUSAZ_03645

SULO:

GFS33_02395(glmM)

SULL:

EWF20_02150(glmM)

MSE:

Msed_0223

MEMJ:

MJ1HA_0308

MCN:

Mcup_1849

MHK:	DFR87_05590(glmM)

MPRU:

DFR88_05505(glmM)

MTEN:

GWK48_05925(glmM)

MJN:	MjAS7_0809

AHO:

Ahos_0595

AMAN:

B6F84_07955

ABRI:

DFR85_06850(glmM)

ASUL:

DFR86_06990(glmM)

AAMB:

D1866_10715(glmM)

ACIH:

HS5_20050

SACD:

HS1genome_0888

SAZO:

D1868_00990(glmM)

CSTY:

KN1_17050

STEP:

IC006_1848

SMET:

RQ359_002370(glmM)

SAHS:

HS7_16760

» show all

Reference

1 [PMID:29507091]

Authors

Dadashipour M, Iwamoto M, Hossain MM, Akutsu JI, Zhang Z, Kawarabayasi Y

Title

Identification of a Direct Biosynthetic Pathway for UDP-N-Acetylgalactosamine from Glucosamine-6-Phosphate in Thermophilic Crenarchaeon Sulfolobus tokodaii.

Journal

J Bacteriol 200:e00048-18 (2018)
DOI:10.1128/JB.00048-18

Sequence

[sto:STK_02420]

Other DBs

ExplorEnz - The Enzyme Database:

5.4.2.13

IUBMB Enzyme Nomenclature:

5.4.2.13

ExPASy - ENZYME nomenclature database:

5.4.2.13

BRENDA, the Enzyme Database:

5.4.2.13

LinkDB

REACTION: R12221

Entry

R12221                      Reaction

Name

alpha-D-galactosamine 1,6-phosphomutase

Definition

D-Galactosamine 6-phosphate <=> alpha-D-Galactosamine 1-phosphate

Equation

C06377 <=> C22029

Reaction class

RC00408

C06377_C22029

Enzyme

5.4.2.13

Pathway

rn00520

Amino sugar and nucleotide sugar metabolism

rn01100

Metabolic pathways

rn01250

Biosynthesis of nucleotide sugars

Module

M01002

UDP-GalNAc biosynthesis, Fru-6P => UDP-GalNAc

Brite

Enzymatic reactions [BR:br08201]
5. Isomerase reactions
  5.4  Intramolecular transferases
   5.4.2  Phosphotransferases (phosphomutases)
    5.4.2.13
     R12221  D-Galactosamine 6-phosphate <=> alpha-D-Galactosamine 1-phosphate

Orthology

K28126

phosphogalactosamine/phosphoglucosamine mutase [EC:5.4.2.13 5.4.2.10]

LinkDB

DBGET integrated database retrieval system