KEGG   ENZYME: 5.5.1.18
Entry
EC 5.5.1.18                 Enzyme                                 
Name
lycopene epsilon-cyclase;
CrtL-e;
LCYe;
carotenoid psi-end group lyase (decyclizing)
Class
Isomerases;
Intramolecular lyases;
Intramolecular lyases (only sub-subclass identified to date)
Sysname
carotenoid psi-end group lyase (ring-opening)
Reaction(IUBMB)
carotenoid psi-end group = carotenoid epsilon-end group
Reaction(KEGG)
(other) R06960 R06963 R07840
Substrate
carotenoid psi-end group
Product
carotenoid epsilon-end group
Comment
The carotenoid lycopene has the psi-end group at both ends. When acting on one end, this enzyme forms delta-carotene. When acting on both ends, it forms epsilon-carotene.
History
EC 5.5.1.18 created 2011
Pathway
ec00906  Carotenoid biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K06444  lycopene epsilon-cyclase
Genes
ATHAT5G57030(LUT2)
ALY9300569
CRB17874924
CSAT104733913 104761775 109124564
EUSEUTSA_v10013234mg
BRP103845139 103856778
BNA106371493 106387316 106418464 106436514
BOE106313003 106328183
RSZ108828178 108844261 130505650 130509272
THJ104811752
CPAP110817683
CIT102578059
CICCICLE_v10008410mg
PVY116113694
MINC123194826
TCC18588358
GRA105769989 105793131
GHI107907128 107932206 107937734 107944259
GAB108472621 108484196
HSYR120131995 120166545 120209704
DZI111300372
EGR104438073
GMX100788180 100790686
GSJ114367952 114388698
PVUPHAVU_009G2303000
VRA106761979
VAR108331502
VUN114164722
VUM124839291
CCAJ109803443
APRC113853293
MTR11438775
TPRA123882911
CAM101509804
PSAT127136406
VVO131632518 131640758
LJALj6g3v1211980.1(Lj6g3v1211980.1)
ADU107479054
AIP107630506
AHF112738293 112790470
LANG109328578
PCIN129309864
FVE101304999
RCN112188431
PPER18771479
PMUM103340735 107880066
PAVI110749277
PDUL117634176
MDM103450601
MSYL126606018
PXB103951887
ZJU107424069
MNT21409938
CSAV115702236
CSV101213753
CMO103498607
BHJ120080543
MCHA111021848
CMAX111465770 111493821
CMOS111444042 111450793
CPEP111799301 111805864
RCU8272573
JCU105637892
HBR110633595
MESC110603501
POP18100367
PEU105110117
PALZ118047969
JRE109009968
CILL122307924
CAVE132165384
QSU112002217
QLO115976084
TWL119995954
VVI100259482(LECY1)
VRI117905657 117907400 117925618
SLY544129(CrtL-e-1)
SPEN107007293
SOT102577922(LCYe)
SSTN125862427
SDUL129870770
CANN107840923
LBB132636893
NTA107789691(LYCe) 107830918
NSY104228679
NTO104113690
NAU109220074
INI109148024
ITR115998223
SIND105161879
OEU111366340
EGT105968091
SSPL121748905 121752194 121806356
SMIL130988432
APAN127264138
HAN110928451 110939526
ECAD122599521
LSV111905476
CCAV112501264
DCR108197060
CSIN114276622
RVL131320055
AEW130782790 130784221
BVG104909057
SOE110791410
CQI110683040 110712885
ATRI130814943
MOF131158118
NNU104600661
MING122063297
TSS122667138
PSOM113294804 113318755
OSA4324196
DOSAOs01t0581300-01(Os01g0581300)
OBR102717564
OGL127782304
BDI100821922
ATS109738556
TDC119276154
TAES123069994
TUA125543989
LPER127342743
LRD124659009
SBI8078213
ZMA100280448
SITA101764899
SVS117859306
PVIR120673640 120707193
PHAI112895026
PDA103723715
EGU105057721
MUS103988322
ZOF122002751 122007002
DCT110115201
PEQ110030128
AOF109835611
MSIN131232602
NCOL116246083
ATR18444744
SMOSELMODRAFT_101391 SELMODRAFT_132340
PPP112284858 112288918
CRECHLRE_06g267600v5
VCNVOLCADRAFT_54924
MNGMNEG_1848
CSLCOCSUDRAFT_41900
CVRCHLNCDRAFT_19656(LCYE)
APROF751_6574
 » show all
Reference
1  [PMID:11226339]
  Authors
Cunningham FX Jr, Gantt E
  Title
One ring or two? Determination of ring number in carotenoids by lycopene epsilon-cyclases.
  Journal
Proc Natl Acad Sci U S A 98:2905-10 (2001)
DOI:10.1073/pnas.051618398
  Sequence
[ath:AT5G57030]
Reference
2  [PMID:12712234]
  Authors
Stickforth P, Steiger S, Hess WR, Sandmann G.
  Title
A novel type of lycopene epsilon-cyclase in the marine cyanobacterium Prochlorococcus marinus MED4.
  Journal
Arch Microbiol 179:409-15 (2003)
DOI:10.1007/s00203-003-0545-4
Other DBs
ExplorEnz - The Enzyme Database: 5.5.1.18
IUBMB Enzyme Nomenclature: 5.5.1.18
ExPASy - ENZYME nomenclature database: 5.5.1.18
BRENDA, the Enzyme Database: 5.5.1.18
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