| Entry |
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| Name |
carboxy-cis,cis-muconate cyclase;
3-carboxymuconate cyclase;
3-carboxy-2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing)
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| Class |
Isomerases;
Intramolecular lyases;
Intramolecular lyases (only sub-subclass identified to date)
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| Sysname |
3-carboxy-2,5-dihydro-5-oxofuran-2-acetate lyase (ring-opening)
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| Reaction(IUBMB) |
3-carboxy-2,5-dihydro-5-oxofuran-2-acetate = 3-carboxy-cis,cis-muconate [RN: R03308]
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| Reaction(KEGG) |
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| Substrate |
3-carboxy-2,5-dihydro-5-oxofuran-2-acetate [CPD: C04553]
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| Product |
3-carboxy-cis,cis-muconate [CPD: C01163]
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| History |
EC 5.5.1.5 created 1972
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| Pathway |
| ec01120 | Microbial metabolism in diverse environments |
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| Orthology |
| K14334 | carboxy-cis,cis-muconate cyclase |
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| Genes |
| NTE: | NEUTE1DRAFT69050(NEUTE1DRAFT_69050) |
| SMP: | 10807819(SMAC4_00654) |
| RTHE: | 98128581(VTJ83DRAFT_7147) |
| FGR: | FGSG_01797 FGSG_09485 |
| FPU: | FPSE_10485 FPSE_11356 |
| FVN: | FVRRES_02139 FVRRES_03929 FVRRES_13258 |
| FVR: | FVEG_13026 FVEG_13891 FVEG_15389 |
| FOX: | FOXG_13515 FOXG_17141 FOXG_17757 |
| NHE: | NECHADRAFT_34285 NECHADRAFT_95122 |
| FFC: | NCS54_00293300 NCS54_00748200 NCS54_00963800 |
| FKR: | NCS57_00288700 NCS57_00486400 NCS57_00789200 |
| FMU: | J7337_004040 J7337_013788 |
| TATV: | 25785626(TrAtP1_000940) |
| TASP: | 36617911(TrAFT101_001491) |
| MAW: | 19246987(J3458_000516) 19247980(J3458_005083) |
| MAJ: | MAA_02127 MAA_02523 MAA_07740 |
| MBRN: | 26239697(CMLE) 26241982(G6M90_00g071080) 26242539(G6M90_00g051000) |
| PCHM: | VFPPC_05325 VFPPC_13112 |
| UVI: | 66066409(UV8b_05632) |
| PLJ: | 28886093(PLICBS_007595) |
| CFJ: | CFIO01_06351 CFIO01_08166 CFIO01_13719 |
| CLUP: | CLUP02_00342 CLUP02_15378 CLUP02_15569 |
| CHIG: | CH63R_05008 CH63R_08134 |
| CDET: | 87942076(CDEST_05573) 87945369(CDEST_08866) |
| ELA: | UCREL1_3619 UCREL1_4578 UCREL1_8893 UCREL1_9455 |
| PFY: | PFICI_05544 PFICI_10416 PFICI_11298 PFICI_11300 PFICI_14718 |
| PSCO: | LY89DRAFT_576208 LY89DRAFT_579583 LY89DRAFT_743822 |
| GLZ: | GLAREA_06984 GLAREA_09387 |
| AOR: | AO090005000349 AO090023000419 |
| AFV: | AFLA_003133 AFLA_006766 |
| PPSF: | 300793466(PFLUO_LOCUS7312) |
| PTRR: | 6339549(PtrM4_028410) |
| BZE: | COCCADRAFT_25253 COCCADRAFT_6173 |
| BSC: | COCSADRAFT_165269 COCSADRAFT_35109 |
| BOR: | COCMIDRAFT_270 COCMIDRAFT_79696 |
| AALT: | CC77DRAFT_1023877 CC77DRAFT_1025708 |
| ZTR: | MYCGRDRAFT_74026 MYCGRDRAFT_99485(MLE) |
| PFJ: | MYCFIDRAFT_210932 MYCFIDRAFT_80983 |
| CBET: | CB0940_06705 CB0940_08522 CB0940_11575 |
| BCOM: | BAUCODRAFT_389389 BAUCODRAFT_80070 |
| NPA: | UCRNP2_3006 UCRNP2_5709 |
| SHS: | STEHIDRAFT_116697 STEHIDRAFT_161496 |
| PSTR: | Pst134EA_022889 Pst134EA_022901 Pst134EA_022933 |
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| Reference |
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| Authors |
GROSS SR, GAFFORD RD, TATUM EL. |
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| Title |
The metabolism of protocatechuic acid by Neurospora. |
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| Journal |
J Biol Chem 219:781-96 (1956) |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 5.5.1.5 |
| ExPASy - ENZYME nomenclature database: | 5.5.1.5 |
| BRENDA, the Enzyme Database: | 5.5.1.5 |
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| LinkDB |
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