KEGG   ENZYME: 6.3.1.11
Entry
EC 6.3.1.11                 Enzyme                                 
Name
glutamate---putrescine ligase;
gamma-glutamylputrescine synthetase;
YcjK
Class
Ligases;
Forming carbon-nitrogen bonds;
Acid-D-ammonia (or amine) ligases (amide synthases)
Sysname
L-glutamate:putrescine ligase (ADP-forming)
Reaction(IUBMB)
ATP + L-glutamate + putrescine = ADP + phosphate + gamma-L-glutamylputrescine [RN:R07414]
Reaction(KEGG)
R07414
Substrate
ATP [CPD:C00002];
L-glutamate [CPD:C00025];
putrescine [CPD:C00134]
Product
ADP [CPD:C00008];
phosphate [CPD:C00009];
gamma-L-glutamylputrescine [CPD:C15699]
Comment
Forms part of a novel bacterial putrescine utilization pathway in Escherichia coli.
History
EC 6.3.1.11 created 2005
Pathway
ec00330  Arginine and proline metabolism
ec01100  Metabolic pathways
Orthology
K09470  gamma-glutamylputrescine synthase
Genes
ECO: b1297(puuA)
ECJ: JW5201(puuA)
ECD: ECDH10B_1414(puuA)
EBW: BWG_1129(puuA)
ECOK: ECMDS42_1095(puuA)
ECOC: C3026_07615
ECE: Z2491
ECS: ECs_1874(puuA)
ECF: ECH74115_1939(puuA)
ETW: ECSP_1822(puuA)
ELX: CDCO157_1794
EOI: ECO111_1680(puuA)
EOJ: ECO26_1864(puuA)
EOH: ECO103_1461(puuA)
ECOO: ECRM13514_1722
ECOH: ECRM13516_1688
ESL: O3K_13845
ESO: O3O_11785
ESM: O3M_13820
ECK: EC55989_1459(puuA)
EOK: G2583_1644(puuA)
ELR: ECO55CA74_08005
ELH: ETEC_1401
ECW: EcE24377A_1506(puuA)
EUN: UMNK88_1630
ECOA: APECO78_10360
ECX: EcHS_A1412(puuA)
ECM: EcSMS35_1825(puuA)
ECY: ECSE_1349
ECR: ECIAI1_1322(puuA)
EUM: ECUMN_1603(puuA)
ECT: ECIAI39_1648(puuA)
EOC: CE10_1545(puuA)
EBR: ECB_01274(ycjK)
ECOB: C3029_10935
EBL: ECD_01274(puuA)
EBE: B21_01285(puuA)
EBD: ECBD_2320
ELO: EC042_1425(puuA)
ECL: EcolC_2328
EKF: KO11_16325(puuA)
EDH: EcDH1_2349
EDJ: ECDH1ME8569_1239(puuA)
ELW: ECW_m1393(puuA)
ELL: WFL_06790(puuA)
ELP: P12B_c1797(puuA)
ECOL: LY180_06605
EAL: EAKF1_ch0121(puuA)
ESZ: FEM44_21585
SFL: SF1302
SFX: S1384
SFV: SFV_1311
SFE: SFxv_1475(puuA)
SFN: SFy_1870
SFS: SFyv_1927
SFT: NCTC1_01377(puuA)
SSN: SSON_1843
SBO: SBO_1765
SBC: SbBS512_E1533(puuA)
SDY: SDY_1947
SDZ: Asd1617_02624
SHQ: A0259_10610
SHIG: LXH19_12170(puuA)
ENC: ECL_02225
ENL: A3UG_10020 A3UG_15575
ECLG: EC036_19410
ECLN: ECNIH4_07635 ECNIH4_12700
EAU: DI57_04170 DI57_08920
EKB: BFV64_10370
ENO: ECENHK_09945 ECENHK_15025
EEC: EcWSU1_03061(puuA)
ELG: BH714_11365
ECAN: CWI88_14355
ERN: BFV67_09515 BFV67_14610
ECLS: LI67_011095 LI67_016160
ECHG: FY206_11410 FY206_16665
ESH: C1N69_15385
EAS: Entas_2914
ENR: H650_07825
ENX: NI40_015070
ENF: AKI40_4007
LNI: CWR52_20020
EBG: FAI37_14080 FAI37_19210
END: A4308_14660 A4308_19690
ENZ: G0034_09785 G0034_15640
EMOR: L6Y89_14715
ENB: ELK40_10335 ELK40_15315
EQU: OM418_09775 OM418_14765
EPU: QVH39_10225 QVH39_15665
EDY: F0320_14595
EAX: AAHF05_14885
ESA: ESA_02078 ESA_04256
CSK: ES15_0194 ES15_2235(puuA)
CSZ: CSSP291_09880 CSSP291_19610
CSJ: CSK29544_01154 CSK29544_03371
CCON: AFK62_18985
CDM: AFK67_08765 AFK67_19615
CSI: P262_00299 P262_03228
CMJ: AFK66_001035 AFK66_010915
CUI: AFK65_08625 AFK65_18695
CMW: AFK63_09865 AFK63_19645
CTU: CTU_18860(puuA) CTU_40070(puuA)
KPN: KPN_01021
KPU: KP1_2006
KPM: KPHS_18960
KPP: A79E_3212
KPH: KPNIH24_19030
KPZ: KPNIH27_08955
KPV: KPNIH29_09485
KPW: KPNIH30_10000
KPY: KPNIH31_09375
KPG: KPNIH32_09840
KPC: KPNIH10_09495
KPQ: KPR0928_09665
KPT: VK055_1456(puuA)
KPO: KPN2242_08165
KPR: KPR_3501(puuA)
KPJ: N559_3266
KPI: D364_05310
KPA: KPNJ1_03507
KPS: KPNJ2_03496
KPX: PMK1_03361(puuA)
KPB: FH42_00960
KPNE: KU54_016660
KPNU: LI86_16970
KPNK: BN49_2109(puuA)
KVA: Kvar_3358
KPE: KPK_3539(puuA)
KPK: A593_19605
KVD: KR75_17275
KVQ: SP68_23655
KQU: AVR78_13935
KQV: B8P98_18165
KOX: KOX_16935
KOE: A225_2235
KOY: J415_20600
KOM: HR38_15455
KMI: VW41_06405 VW41_14385
KOK: KONIH1_10935
KOC: AB185_25200
EAE: EAE_15935
EAR: CCG30720
KLL: BJF97_11210
KLW: DA718_17640
KAR: LGL98_16120
KGR: JJJ10_17590(puuA)
KPAS: LUW96_17555(puuA)
KLC: K7H21_17305(puuA)
KLM: BWI76_10710
KLP: GUC22_16565
ROR: RORB6_09555
RON: TE10_11025
RAO: DSD31_16190
RTG: NCTC13098_04765(puuA_1)
CRO: ROD_03561(puuA)
CFD: CFNIH1_11625
CBRA: A6J81_11665
CYO: CD187_18785
CPOT: FOB25_06240
CFQ: C2U38_05165
CIE: AN232_24810
CITZ: E4Z61_12070
CARS: E1B03_06255
CIX: M4I31_18385
CIB: HF677_018360
CITR: GUC46_18320
CNT: JT31_05805 JT31_20735
CEM: LH23_12125 LH23_20340
CEN: LH86_11535 LH86_18975
CLAP: NCTC11466_03162(puuA)
PGE: LG71_13300
ESC: Entcl_1590 Entcl_1710
KLE: AO703_13440 AO703_14000
KSA: C813_22630
KRD: A3780_16470
KPSE: IP581_16080
KOO: O9K67_19745
KOU: C0557_17990
LAZ: A8A57_07995
LEF: LJPFL01_2811
BSEL: RHD99_09175
YRE: HEC60_09600
SGOE: A8O29_008305
KIN: AB182_12295
IZH: FEM41_12205
PSGC: G163CM_17510(puuA)
SCOL: KFZ77_08015
TOE: QMG90_13640
FPUL: ACBV55_11075 ACBV55_13000
EBF: D782_2781
EBU: CUC76_06180
EBB: F652_551
PSTS: E05_49370
SMAR: SM39_1531(puuA) SM39_2780 SM39_4908
SMAC: SMDB11_1341(puuA) SMDB11_2544 SMDB11_4654
SMW: SMWW4_v1c05240 SMWW4_v1c20870 SMWW4_v1c33120
SPE: Spro_0584 Spro_2068 Spro_3216
SRR: SerAS9_0522 SerAS9_2005 SerAS9_3356
SRL: SOD_c04620(puuA1) SOD_c18800(puuA2) SOD_c31290(puuA)
SRY: M621_02375 M621_10370 M621_17055
SPLY: Q5A_002500(puuA_1) Q5A_010400(puuA_2) Q5A_017000(puuA_3)
SRS: SerAS12_0522 SerAS12_2005 SerAS12_3357
SRA: SerAS13_0522 SerAS13_2006 SerAS13_3359
SMAF: D781_0539 D781_1892
SLQ: M495_02295 M495_10025 M495_16450
SERF: L085_01440 L085_12115 L085_18330
SERS: SERRSCBI_02540 SERRSCBI_09780 SERRSCBI_15985
SFW: WN53_19620 WN53_24965
SFG: AV650_14995 AV650_20605
SRZ: AXX16_3237 AXX16_4570
SERM: CLM71_02615 CLM71_09395
SQU: E4343_05875 E4343_13730 E4343_24710
SFJ: SAMEA4384070_0608(puuA_1) SAMEA4384070_2125(puuA_2) SAMEA4384070_3327(puuA_3)
SOF: NCTC11214_03509(puuA_2) NCTC11214_04758(puuA_3)
SSUR: ATE40_006930 ATE40_013075 ATE40_023330
SURI: J0X03_07455 J0X03_13565 J0X03_21300
SRHZ: FO014_00155 FO014_07205
SENP: KHA73_02355 KHA73_10460 KHA73_16090
SNEM: NLX84_02545 NLX84_10520 NLX84_16530
SNEV: OI978_03880 OI978_15990 OI978_22825
SGRI: SGBXF1_00526(puuA_1) SGBXF1_02084(puuA_2) SGBXF1_03255(puuA_3)
SSAR: SSARUM_000501 SSARUM_001994 SSARUM_003177
SERB: QEP77_05990 QEP77_20325
SFO: Z042_02945 Z042_23800
RAH: Rahaq_1578
RACE: JHW33_02140
RAQ: Rahaq2_1642
RAA: Q7S_07630
ROX: BV494_03025 BV494_18795
RVC: J9880_15630
RBON: QNM34_08145 QNM34_10980
RIU: I2123_16125
EAME: GXP68_07190
RBAD: H2866_00975
RCB: O1V66_02920
CARU: P0E69_06635
NIG: C1N62_05490
CED: LH89_04065
DFN: CVE23_08755
DAQ: DAQ1742_00071(puuA)
DLC: O1Q98_11295
SOD: Sant_1485(puuA)
SLIG: GTU79_18195
EBI: EbC_29010
EPE: CI789_04205
ERWI: GN242_07305
ERP: LJN55_15055
EPI: Q3V30_07540
ERWE: GKQ23_09215
ETO: RIN69_14695
EGE: EM595_2349(puuA)
PAM: PANA_2462(puuA)
PLF: PANA5342_1624(ycjK)
PAJ: PAJ_1759(puuA)
PAQ: PAGR_g1567
PVA: Pvag_1945(ycjK)
PAGG: AL522_16620
PAO: Pat9b_2554
KLN: LH22_09820
PANT: PSNIH1_15795
PANP: PSNIH2_05250
PAGC: BEE12_00315
PSTW: DSJ_15835
PALH: B1H58_14675
PANS: FCN45_12310
PEY: EE896_06985
PDIS: D8B20_10930
PER: LAC65_09780
PJI: KTJ90_06755
PANO: OJ965_09210
KPIE: N5580_06305
PALF: K6R05_06845
PPHO: CTZ24_15825
PDIP: KFZ74_07645
PANE: P6287_12210
PAMT: IAI47_07125
PANZ: NR302_12090
PGZ: C2E15_13340
PCD: C2E16_13550
MINT: C7M51_01856(puuA)
MTHI: C7M52_00954(puuA)
MHAN: K6958_13025
PMAK: PMPD1_2813
HAV: AT03_07550
HPAR: AL518_18040
OPO: DSM2777_12835
VPA: VP1781
VPB: VPBB_1637
VPK: M636_13180
VPF: M634_10405
VPH: VPUCM_1860
VAG: N646_0402
VNA: PN96_04975
VEJ: VEJY3_08300
VFU: vfu_A02176
VFL: AL536_14615
VBR: A6E01_13670
VSH: BSZ05_19070
VNL: D3H41_06780
VKA: BTD91_16580
VPG: LZI70_19120
VIB: VspSTUT11_17090
VCK: PG915_18030
PGH: FH974_08430
PHOT: L4174_019295
ACB: A1S_2136
ABM: ABSDF1602
ABY: ABAYE1425
ABC: ACICU_02336
ABN: AB57_2469
ABB: ABBFA_01311(puuA)
ABX: ABK1_1353
ABZ: ABZJ_02488
ABR: ABTJ_01407
ABD: ABTW07_2528
ABH: M3Q_2584
ABAD: ABD1_21350
ABJ: BJAB07104_02492
ABAB: BJAB0715_02519
ABAJ: BJAB0868_02375
ABAZ: P795_6275
ABK: LX00_11555
ABAU: IX87_06670
ABAA: IX88_13220
ABW: BL01_17250
ABAL: ABLAC_13710
ACC: BDGL_001623(puuA)
ANO: RR32_07165
ALC: OTEC02_06675
ACAL: BUM88_12160
ASEI: I8T81_07055
ACD: AOLE_06470
AJO: RZ95_14110
ACW: A0J50_06445
ASOL: BEN76_01595
ARJ: DOM24_09745
ACUM: C9E88_001415
AGU: AS4_00340(puuA)
AUG: URS_2283
ADS: FPL17_18450
ABER: BSR55_21030
ACHI: CDG60_17815
AGYL: FPL18_11030
ATZ: M5E07_06380
APRL: PY247_01255
ACOI: NQU59_07325
ACIE: KIP84_06630
HAA: A5892_00915
EMP: EZMO1_3512(puuA)
ASR: WL1483_2278(puuA)
ASIM: FE240_03990
OCE: GU3_14525
OPE: PU634_02240
ZDF: AN401_15160
GAW: V144x_10440(glnA_1)
MSG: MSMEI_3737
MSB: LJ00_19010
MSN: LI99_19015
MSH: LI98_19020
SBAE: DSM104329_04933
KOV: K9N68_06075
NLK: NIES25_13660
HAXZ: M0R88_09125
HHI: HAH_4293(glnA2)
HHN: HISP_16680
HAB: SG26_00890
HAAD: MW046_08100
HME: HFX_1688(glnA)
HLS: KU306_18515
HBO: Hbor_38380
HRA: EI982_01260
SRUB: C2R22_13375
HALG: HUG10_07595
HLR: HALLA_03560
 » show all
Reference
1  [PMID:15590624]
  Authors
Kurihara S, Oda S, Kato K, Kim HG, Koyanagi T, Kumagai H, Suzuki H.
  Title
A novel putrescine utilization pathway involves gamma-glutamylated intermediates of Escherichia coli K-12.
  Journal
J Biol Chem 280:4602-8 (2005)
DOI:10.1074/jbc.M411114200
  Sequence
[eco:b1297]
Other DBs
ExplorEnz - The Enzyme Database: 6.3.1.11
IUBMB Enzyme Nomenclature: 6.3.1.11
ExPASy - ENZYME nomenclature database: 6.3.1.11
BRENDA, the Enzyme Database: 6.3.1.11
CAS: 914090-78-1
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