KEGG ENZYME: 6.3.2.32

ENZYME: 6.3.2.32

Entry

EC 6.3.2.32                 Enzyme

Name

coenzyme gamma-F420-2:alpha-L-glutamate ligase;
MJ1001;
CofF protein;
gamma-F420-2:alpha-L-glutamate ligase

Class

Ligases;
Forming carbon-nitrogen bonds;
Acid-D-amino-acid ligases (peptide synthases)

Sysname

L-glutamate:coenzyme gamma-F420-2 (ADP-forming)

Reaction(IUBMB)

ATP + coenzyme gamma-F420-2 + L-glutamate = ADP + phosphate + coenzyme alpha-F420-3 [RN:R09401]

Reaction(KEGG)

R09401

Substrate

ATP [CPD:C00002];
coenzyme gamma-F420-2 [CPD:C00876];
L-glutamate [CPD:C00025]

Product

ADP [CPD:C00008];
phosphate [CPD:C00009];
coenzyme alpha-F420-3 [CPD:C19151]

Comment

The enzyme caps the gamma-glutamyl tail of the hydride carrier coenzyme F420 [1].

History

EC 6.3.2.32 created 2010

Pathway

ec00680

Methane metabolism

ec01100

Metabolic pathways

ec01120

Microbial metabolism in diverse environments

Orthology

K14940

gamma-F420-2:alpha-L-glutamate ligase

Genes

SON:	SO_2200(rimK)

SAZ:

Sama_1999

SBL:

Sbal_1848

SBM:	Shew185_1834

SBN:	Sbal195_1882

SBP:	Sbal223_2443

SBT:	Sbal678_1921

SBS:	Sbal117_1966

SBB:	Sbal175_2505

SPC:	Sputcn32_1744

SHP:	Sput200_1771

SHE:	Shewmr4_2195

SHM:	Shewmr7_2272

SHN:	Shewana3_2405

SHW:	Sputw3181_2281

SHF:	CEQ32_03360

SBJ:	CF168_08980

SHEW:

CKQ84_21855

SALG:

BS332_16795

SKH:	STH12_01689(rimK_4)

SLIT:

JQC75_10225

SCAA:

TUM17387_22460(rimK)

SCYP:

JYB88_07550

SSEM:

JYB85_07750

SXM:	MKD32_11265

SHEJ:

MZ182_08680

SSEH:

N7V09_11325

SCHK:

GII14_12750

SACH:

K0H61_07370

SDEO:

D0436_12785

SZH:	K0H63_11225

SMAY:

K0H60_11805

SOG:	RA178_13195

SHEL:

JM642_09100

SHEP:

AYJ58_11870

TVD:	SG34_028010

PSEO:

OM33_05960

PRR:	AT705_00405

PPIS:

B1L02_10160

PSPO:

PSPO_a0609(cofF)

PTU:	PTUN_a3869(cofF)

PSEN:

PNC201_06600(rimK1)

PDJ:	D0907_18800

PXI:	J5O05_16465

PVB:	J5X90_12805

PFLI:

CTT31_06700

PMAZ:

R5H13_07255

PSHO:

KQ246_19540

PSJS:

GZH31_19665

PSRR:

ELR70_17335

PSMB:

H3302_17280

PSCF:

L3Q70_20300

FBL:	Fbal_1405 Fbal_3320

LHA:

LHA_0303

LCD:	clem_13645(rimK_3)

LGT:	E4T54_06750

LCAD:

PXX05_12255

MGEO:

CFI10_11795

MSEC:

LN244_09405

BNU:	N3Z17_05510

TSV:	DSM104635_01004(lysX)

THAA:

CFI11_16260

CBOT:

ATE48_15055

NRE:	BES08_00495

NOV:	TQ38_005500

NOVB:

ACFFDA_27235

SPHM:

G432_12675

SSAN:

NX02_01805 NX02_02790

SMAZ:

LH19_12250

SPUS:

KEC45_05845

SPJJ:

V6U71_07335

SUFL:

FIL70_03915

CMAN:

A9D14_02485

DVE:	DESUT3_08310

TAV:	G4V39_06485

MAI:

MICA_511

MAN:

A11S_494

BMX:

BMS_2472

WCH:	wcw_1112(rimK)

SNG:	SNE_A10260(rimK)

SFC:	Spiaf_0383

SPER:

EW093_12210

PSTY:

BFS30_01295

FSD:	LXD69_15515

PROC:

Ptc2401_00937(lysX_1)

BSHI:

LGQ02_14785

BCO:	Bcell_3109 Bcell_3110

BHK:	B4U37_16110

OIH:

OB2060

OKM:	ACN6MR_10345 ACN6MR_10350

TAP:	GZ22_09970

TAID:

KS242_11130

VIR:	X953_09135

VHL:	BME96_08025

VIG:	BKP57_01650

VIL:	CFK37_13350 CFK37_13355

VNE:	CFK40_08770

VPN:	A21D_03084(lysX) A21D_03085(rimK)

VSS:	PD280_14505

LAO:	AOX59_06080

PFRI:

L8956_18255

AQT:	FN924_11475

GRC:	GI584_04560

GCS:	MUN88_01790 MUN88_01795

GSM:	MUN87_17845 MUN87_17850

POF:	GS400_14495

SEDD:

ERJ70_12135

CTHU:

HUR95_15415

BBEV:

BBEV_0975(rimK-2)

GAJ:	MY490_21310

ACHP:

QR721_08535

BBAM:

RJD24_15965

FEC:	QNH15_16975

EMEX:

ACNOIU_09905

PMAE:

LMZ02_24295

ANEU:

PP175_22560

OCW:	OW730_09790 OW730_14795

AWO:	Awo_c26080 Awo_c26090

AWI:	CHL1_000930 CHL1_000931

AMAJ:

ACIUZZ_04900 ACIUZZ_04905

HSC:	HVS_08555(rimK2)

ANR:	Ana3638_16390

ACEL:

acsn021_27150

ACHT:

bsdcttw_29060

SSUN:

H9Q77_00155

CBAR:

PATL70BA_1083

CSPO:

QNI18_05295

TEB:	T8CH_0003(rimK)

THYR:

P4S50_17695

CDAN:

SOJ16_001452

CGV:	CGLAU_09760(rimK)

CLIZ:

G7Y31_08915

CLUJ:

IAU68_08985

CCOY:

CCOY_09345(rimK)

CHAD:

CHAD_09510(rimK)

CGOI:

CGOTT_09160(rimK)

STGO:

KBP30_38570

STCZ:

JHY03_72660(gshB_1) JHY03_72860(gshB_2)

STHU:

M1P56_21680

ACIT:

HPK19_17060 HPK19_17065

BFK:	QN062_02910

AFO:

Afer_0709

PMET:

G4Y79_21850

CDES:

C0J27_04220

MJA:

MJ_1001

MFE:	Mefer_1229

MVU:	Metvu_1301

MFS:	MFS40622_1616

MIF:	Metin_0765

MJH:	JH146_0956

MESG:

MLAUSG7_0153(cofF)

MESA:

MLASG1_1332(cofF)

MIG:	Metig_0022

MMP:	MMP0170(cofF)

MMQ:	MmarC5_1505

MMX:	MmarC6_0780

MMZ:	MmarC7_1170

MMD:

GYY_00870

MMAK:

MMKA1_01750(cofF)

MMAO:

MMOS7_02010(cofF)

MMAD:

MMJJ_09140(rimK_2)

MAE:

Maeo_1379

MVN:	Mevan_1175

MVO:	Mvol_1166 Mvol_1455

MOK:	Metok_0654

METF:

CFE53_01290(cofF)

FPL:

Ferp_2172

MAC:	MA_1361(rimK)

MMA:

MM_2347

MMAZ:

MmTuc01_2397

MMJ:	MSMAS_2353

MMAC:

MSMAC_2094

MLS:	MSLAZ_0946

MEF:	MSWH1_2290

MEQ:	MSWHS_2785

MHOR:

MSHOH_2976

MHAB:

RSJ42_02735

MMET:

MCMEM_1893

MELO:

J7W08_08415

MZH:	Mzhil_0669

MPY:	Mpsy_2134(rimK)

MMAV:

RE476_03540

MSEB:

RE474_13245

MOU:	OU421_11895

» show all

Reference

1 [PMID:12909715]

Authors

Li H, Xu H, Graham DE, White RH

Title

Glutathione synthetase homologs encode alpha-L-glutamate ligases for methanogenic coenzyme F420 and tetrahydrosarcinapterin biosyntheses.

Journal

Proc Natl Acad Sci U S A 100:9785-90 (2003)
DOI:10.1073/pnas.1733391100

Sequence

[mja:MJ_1001]

Other DBs

ExplorEnz - The Enzyme Database:

6.3.2.32

IUBMB Enzyme Nomenclature:

6.3.2.32

ExPASy - ENZYME nomenclature database:

6.3.2.32

BRENDA, the Enzyme Database:

6.3.2.32

LinkDB

DBGET integrated database retrieval system