KEGG ENZYME: 6.3.2.52

ENZYME: 6.3.2.52

Entry

EC 6.3.2.52                 Enzyme

Name

jasmonoyl---L-amino acid ligase;
JAR1 (gene name);
JAR4 (gene name);
JAR6 (gene name);
jasmonoyl---L-amino acid synthetase

Class

Ligases;
Forming carbon-nitrogen bonds;
Acid-D-amino-acid ligases (peptide synthases)

Sysname

jasmonate:L-amino acid ligase

Reaction(IUBMB)

ATP + jasmonate + an L-amino acid = AMP + diphosphate + a jasmonoyl-L-amino acid [RN:R11950]

Reaction(KEGG)

R11950

Substrate

ATP [CPD:C00002];
jasmonate [CPD:C08491];
L-amino acid [CPD:C00151]

Product

AMP [CPD:C00020];
diphosphate [CPD:C00013];
jasmonoyl-L-amino acid [CPD:C21509]

Comment

Two jasmonoyl-L-amino acid synthetases have been described from Nicotiana attenuata [3] and one from Arabidopsis thaliana [1]. The N. attenuata enzymes generate jasmonoyl-L-isoleucine, jasmonoyl-L-leucine, and jasmonoyl-L-valine. The enzyme from A. thaliana could catalyse the addition of many different amino acids to jasmonate in vitro [1,4,5]. While the abundant form of jasmonate in plants is (-)-jasmonate, the active form of jasmonoyl-L-isoleucine is (+)-7-iso-jasmonoyl-L-isoleucine.

History

EC 6.3.2.52 created 2018, modified 2019

Orthology

K14506

jasmonic acid-amino synthetase

Genes

ATH:	AT2G46370(JAR1)

ALY:

9316303

CRB:

17887579

CSAT:

104783209 104784678 104793611

EUS:	EUTSA_v10001373mg

BRP:	103858212 103866275 103866475

BNA:	106392009 106415372 106438277 106441911 106446159 106453225

BOE:	106327971 106337574 106342461

RSZ:	108813817 108844535 108844539 108853684

THJ:	104802061 104817340

CPAP:

110810413

CIT:	102611440 127898602

CIC:	CICLE_v10019459mg

PVY:

116121118

MINC:

123216584 123216586 123223803 123224207

TCC:

18614015

GRA:	105791543 105796195 105802782 105802783

GHI:	107900937 107909787 107909788 107923052 107923326 107933526 107952940 107954506

GAB:	108460785 108467411 108472614 108472695

HSYR:

120165361 120188923 120204509

DZI:	111304817 111313931

EGR:	104442158 104443381

GMX:	100777944 100794598 100806209 100813492

GSJ:	114390517 114400143 114407792 114418331

PVU:	PHAVU_006G110900g PHAVU_010G111400g

VRA:	106754140 106773156

VAR:	108318909 108346002

VUN:	114166370 114166795 114188102

VUM:	124835328 124836775

CCAJ:

109797239 109808861

APRC:

113849948 113861096

MTR:	11431770 25500734 25500738 25500739

TPRA:

123884325 123889590

CAM:	101500743 101504683 101506624 101506959

PSAT:

127076053 127076055 127076057 127132140

VVO:	131598105 131599975 131610730 131618284 131618293 131618297 131618299 131618300 131618301 131618303 131618305 131618307

LJA:	130731376 130746233

ADU:	107472946 107491964

AIP:	107623354 107645717

AHF:	112695332 112726459 112733726 112758416

LANG:

109333135 109357385 109357386 109359450 109359672

PCIN:

129288680 129291174 129291598 129301529

QSA:	O6P43_017742 O6P43_027345

FVE:

101296802

RCN:

112181918

PPER:

18784809

PMUM:

103332267

PAVI:

110751778

PDUL:

117618563

MDM:	103413018 103439296

MSYL:

126621257 126627789

PXB:

103965897

ZJU:	107424151 107429109

MNT:

21386318

CSAV:

115705838

CSV:

101212037

CMO:

103483208

BHJ:

120085218

MCHA:

111016355 111025068

CMAX:

111473333 111475727 111479304 111479305

CMOS:

111432047 111432219 111446696

CPEP:

111790647 111790648 111800387

RCU:

8263567

MEAN:

126687289

JCU:

105642878

HBR:	110645079 110670437

MESC:

110614736 110615559

POP:	7494139 7497237

PEU:	105124788 105134892

PALZ:

118041545 118057695

JRE:	108985239 108996457

CILL:

122299570 122310967

CAVE:

132186572

QSU:

111985652

QLO:

115986524

TWL:	119982545 119983271

VVI:

100251627

SLY:	101250455 101251682 101262053 101262357 101262663 101268624 101268670

SPEN:

107001869 107002523 107002524 107007864 107020374 107022768

SOT:	102578750 102600861 102603612

SSTN:

125850397 125864555 125867065

SDUL:

129877389 129880718 129886480

CANN:

107839284 107845604

LBB:	132632427 132632441 132640670 132645479

NTA:	107761031 107769747 107772988 107774940 107798053 107798060 107806520 107811464

NSY:	104209986 104236492 104248247

NTO:	104084467 104090951 104096608 104110129 104110130

NAU:	109207440 109211394 109219431

INI:	109180806(JAR)

ITR:

116029416

SIND:

105173100 105173433

OEU:

111377782

EGT:	105956350 105963883

SSPL:

121761580 121775029 121777678 121804684 121806418

SMIL:

130998915 131020786

SHIS:

125189969 125194255 125201669

APAN:

127261193 127263319

HAN:	110864821 110917855 110922359 110937608

ECAD:

122590706 122596687 122597751 122598238

LSV:	111876787 111894588

CCAV:

112522684 112526954 112529803

DCR:	108196757 108209455

CSIN:

114259899 114260773 114283086 114296732 114323877

RVL:

131334587

AEW:	130753923 130783948

BVG:

104886569

SOE:	110775233 110775235 110790433

CQI:	110714357 110714358 110714527 110725039 110725063 110725177

ATRI:

130810360

MOF:

131165953

NNU:	104600319 104603960 109115461

MING:

122081186 122082359 122092725

TSS:	122639755 122645437 122664782

PSOM:

113323681 113340287

OSA:	4339756(GH3.5)

OBR:

102716971

OGL:

127773653

BDI:

100821807

ATS:

109785424

TDC:	119294130 119349753

TAES:

123069945 123148866 123183299

TUA:

125531522

LPER:

127327812 127327815

LRD:	124649283 124649290 124706963

SBI:	8065295 8084842

ZMA:	100280367 100381512

MFLO:

136450170 136512779 136514881

SITA:

101771047 101779619 101781042

SVS:	117833908 117848434 117857665

PVIR:

120664477 120697698 120707450

PHAI:

112886030 112893299 112903383

PDA:	103708344 103708705 103716872

EGU:	105036519 105047558 105048226

MUS:	103980034 103980944 103981532 103992744 103996308

ZOF:	121981933 121985773 122010259 122014146 122026917 122031793 122033694

DCT:	110100668 110104139

PEQ:	110019693 110038389

AOF:	109828888 109847377 109847394

MSIN:

131217330 131241302 131245063

NCOL:

116260089

ATR:

18426859

SMO:

SELMODRAFT_124989(JAR1L8-1) SELMODRAFT_125145(JAR1L7-1) SELMODRAFT_125443(JAR1L1-2) SELMODRAFT_128888(JAR1L7-2) SELMODRAFT_21596(JAR1L6-2) SELMODRAFT_234778(JAR1L1-1) SELMODRAFT_235186(JAR1L2-2) SELMODRAFT_31681(JAR1L3-1) SELMODRAFT_31683(JAR1L3-2) SELMODRAFT_416246(JAR1L2-1) SELMODRAFT_427552(JAR1L8-2) SELMODRAFT_437924(JAR1L5-1) SELMODRAFT_441348(JAR1L5-2)

PPP:

112287761

» show all

Reference

1 [PMID:15258265]

Authors

Staswick PE, Tiryaki I

Title

The oxylipin signal jasmonic acid is activated by an enzyme that conjugates it to isoleucine in Arabidopsis.

Journal

Plant Cell 16:2117-27 (2004)
DOI:10.1105/tpc.104.023549

Sequence