Entry
Name
ABC-type thiamine transporter;
thiamin transporting ATPase;
thiamine ABC transporter;
thiamin ABC transporter;
thiamine transporting ATPase;
thiBPQ (gene names)
Class
Translocases;
Catalysing the translocation of other compounds;
Linked to the hydrolysis of a nucleoside triphosphate
BRITE hierarchy
Sysname
ATP phosphohydrolase (ABC-type, thiamine-importing)
Reaction(IUBMB)
ATP + H2O + thiamine-[thiamine-binding protein][side 1] = ADP + phosphate + thiamine[side 2] + [thiamine-binding protein][side 1]
Substrate
ATP [CPD:
C00002 ];
H2O [CPD:
C00001 ];
thiamine-[thiamine-binding protein][side 1]
Product
ADP [CPD:
C00008 ];
phosphate [CPD:
C00009 ];
thiamine[side 2];
[thiamine-binding protein][side 1]
Comment
ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins. The enzyme, characterized from the bacterium Salmonella typhimurium, is a heterodimeric complex that interacts with an extracytoplasmic substrate binding protein and functions to import thiamine, thiamine monophosphate and thiamine diphosphate.
History
EC 7.6.2.15 created 2019
Orthology
K02062 thiamine transport system ATP-binding protein
Genes
ECOO : ECRM13514_0068(thiQ)
ECOH : ECRM13516_0070(thiQ)
ELR : ECO55CA74_00335(thiQ)
ECW : EcE24377A_0068(thiQ)
ECOA : APECO78_03780(thiQ)
EDJ : ECDH1ME8569_0065(thiQ)
ECOI : ECOPMV1_00069(thiQ)
SEM : STMDT12_C01060(thiQ)
SENH : CFSAN002069_08705(thiQ)
SEEH : SEEH1578_09555(thiQ)
SENJ : CFSAN001992_10480(thiQ)
SEEC : CFSAN002050_06975(thiQ)
SENC : SEET0819_07410(thiQ)
REE : electrica_04270(thiQ)
RTG : NCTC13098_06235(thiQ_2)
CLAP : NCTC11466_03859(thiQ)
KIE : NCTC12125_02972(thiQ)
AHN : NCTC12129_04193(thiQ)
METY : MRY16398_47570(thiQ)
PTF : PROFFT_A_05190(thiQ)
PSHI : SAMEA2665130_2667(thiQ)
MPHG : MPHASIOC01_004539(thiQ)
YPG : YpAngola_A2945(thiQ)
YPI : YpsIP31758_3416(thiQ)
SMW : SMWW4_v1c07210(thiQ)
SERS : SERRSCBI_03300(thiQ)
SFJ : SAMEA4384070_0757(thiQ)
SOF : NCTC11214_00799(thiQ)
SSAR : SSARUM_000664(thiQ)
SERA : Ser39006_006040(thiQ)
PAQU : DMB82_0017310(thiQ)
PARL : PEC302110_05760(thiQ)
DIC : Dpoa569_0000599(thiQ)
TPTY : NCTC11468_03117(thiQ)
PRG : RB151_035900(thiQ_2)
PHEI : NCTC12003_03100(thiQ)
PRJ : NCTC6933_03200(thiQ)
LRI : NCTC12151_02638(thiQ)
HIC : NTHIC486_01758(thiQ)
HPIT : NCTC13334_01316(thiQ)
HHZ : NCTC10839_00735(thiQ)
HAEG : NCTC8502_02051(thiQ)
PDAG : 4362423_00513(thiQ)
ADP : NCTC12871_00133(thiQ_1)
ALIG : NCTC10568_01634(thiQ)
ASEG : NCTC10977_01731(thiQ)
AVT : NCTC3438_01185(thiQ)
RPNE : NCTC8284_03043(thiQ_1)
PAET : NCTC13378_01167(thiQ)
VPL : SA104470976_00288(thiQ)
VIB : VspSTUT11_26470(thiQ)
VIS : VspSTUT16_27650(thiQ)
GAI : IMCC3135_32200(thiQ)
AEL : NCTC12917_03482(thiQ_2)
CHJ : NCTC10426_00344(thiQ)
CDIZ : CEDIAZO_02976(thiQ)
NMX : NMA510612_0418(potA-2)
NWE : SAMEA3174300_1824(potA_2)
NZO : SAMEA4504057_0127(fbpC_1)
NCZ : NCTC10294_01363(potA_2)
NANI : NCTC12227_01788(cysA_2)
LIH : L63ED372_01211(phnT)
MESU : LHFGNBLO_001488(thiQ)
SMEL : SM2011_c03871(thiQ)
SFD : USDA257_c57210(thiQ)
SAME : SAMCFNEI73_Ch3635(thiQ)
AGR : AGROH133_09063(thiQ)
AVV : RvVAT039_15590(thiQ)
AVF : RvVAR031_02660(thiQ)
RTR : RTCIAT899_CH17955(thiQ)
RGA : RGR602_CH03934(thiQ)
NGL : RG1141_CH37240(thiQ)
NEN : NCHU2750_35270(thiQ)
LAS : CLIBASIA_02230(thiQ)
BSG : IY72_08415 IY72_14055
RLI : RLO149_c040470(thiQ)
PHP : PhaeoP97_03303(thiQ)
PPIC : PhaeoP14_03209(thiQ)
SINL : DSM14862_00199(thiQ)
SPSE : SULPSESMR1_03016(thiQ)
LALG : LentiSH36_02618(thiQ)
LVS : LOKVESSMR4R_03633(thiQ)
PALW : PSAL_026210(thiQ_1)
SAMB : SAM23877_5377(fbpC)
SLE : sle_20310(sle_20310)
SGM : GCM10017557_22300(fbpC)
STUI : GCM10017668_51360(fbpC)
SHUN : DWB77_02243(potA_2)
SXT : KPP03845_105363(potA_2)
NANO : G5V58_02745 G5V58_24685
NAQU : ENKNEFLB_00560(cysA_1)
NPC : KUV85_00370 KUV85_15490
TBW : NCTC13354_01255(fbpC2)
AHW : NCTC11636_01524(fbpC2)
AIR : AIF0345_0220(btuD_24)
ASLA : NCTC11923_00799(fbpC)
AVC : NCTC10951_02418(fbpC2)
PARQ : DSM112329_03821(cysA_2)
IAM : HC251_21710 HC251_24295
DRB : N0D28_03845 N0D28_04940
» show all
Taxonomy
Reference
Authors
Webb E, Claas K, Downs D
Title
thiBPQ encodes an ABC transporter required for transport of thiamine and thiamine pyrophosphate in Salmonella typhimurium.
Journal
Sequence
Other DBs
ExplorEnz - The Enzyme Database: 7.6.2.15
ExPASy - ENZYME nomenclature database: 7.6.2.15
LinkDB
All DBs