KEGG   COMPOUND: C03378
Entry
C03378                      Compound                               
Name
Coagulation factor VIIa
Sequence
(Light chain)
ANAFLEELRP GSLERECKEE QCSFEEAREI FKDAERTKLF WISYSDGDQC ASSPCQNGGS
CKDQLQSYIC FCLPAFEGRN CETHKDDQLI CVNENGGCEQ YCSDHTGTKR SCRCHEGYSL
LADGVSCTPT VEYPCGKIPI LEKRNASKPQ GR
(Heavy chain)
IVGGKVCPKG ECPWQVLLLV NGAQLCGGTL INTIWVVSAA HCFDKIKNWR NLIAVLGEHD
LSEHDGDEQS RRVAQVIIPS TYVPGTTNHD IALLRLHQPV VLTDHVVPLC LPERTFSERT
LAFVRFSLVS GWGQLLDRGA TALELMVLNV PRLMTQDCLQ QSRKVGDSPN ITEYMFCAGY
SDGSKDSCKG DSGGPHATHY RGTWYLTGIV SWGQGCATVG HFGVYTRVSQ YIEWLQKLMR
SEPRPGVLLR APFP
(Disulfide bridge: L135-H110)
  Organism
Homo sapiens [HSA:2155]
  Type
Peptide
Remark
Same as: D00172
Pathway
map04610  Complement and coagulation cascades
Network
nt06514  Coagulation cascade
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 B BLOOD AND BLOOD FORMING ORGANS
  B02 ANTIHEMORRHAGICS
   B02B VITAMIN K AND OTHER HEMOSTATICS
    B02BD Blood coagulation factors
     B02BD05 Coagulation factor VII
      D00172  Eptacog alfa (INN) <JP/US>
     B02BD08 Coagulation factor VIIa
      D00172  Eptacog alfa (INN) <JP/US>
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  63  Biological preparations
   634  Human blood preparations
    6343  Plasma preparations
     D00172  Eptacog alfa (INN); Eptacog alfa (activated) (genetical recombination) (JAN)
Drug groups [BR:br08330]
 Blood modifier agent
  DG02016  Hemostatics
   DG02014  Blood coagulation accelerant
    DG02013  Blood coagulation factor
     DG00172  Blood coagulation factor VII
      D00172  Eptacog alfa
New drug approvals in the USA [br08319.html]
 Cellular and gene therapy products
  D00172
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D00172
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D00172
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D00172
Other DBs
ChEBI: 3777
LinkDB

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