KEGG   COMPOUND: C07022Help
Entry
C07022                      Compound                               

Name
Glyburide;
Glibenclamide
Formula
C23H28ClN3O5S
Exact mass
493.1438
Mol weight
494.0035
Structure
Mol fileKCF fileDB search
Remark
Same as: D00336
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A10 DRUGS USED IN DIABETES
   A10B BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
    A10BB Sulfonylureas
     A10BB01 Glibenclamide
      D00336  Glyburide (USP) <JP/US>
USP drug classification [BR:br08302]
 Blood Glucose Regulators
  Antidiabetic Agents
   Glyburide
    D00336  Glyburide (USP)
Therapeutic category of drugs in Japan [BR:br08301]
 3  Agents affecting metabolism
  39  Other agents affecting metabolism
   396  Antidiabetic agents
    3961  Sulfonylureas
     D00336  Glyburide (USP); Glibenclamide (JP17/INN)
Target-based classification of drugs [BR:br08310]
 Transporters
  ABC transporters
   ABCC subfamily
    ABCC8(SUR1)/KCNJ11(KIR6.2)
     D00336  Glyburide (USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00336  Glibenclamide
Drug classes of therapeutic agents [br08360.html]
 Antidiabetic agents
  D00336
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D00336
Pharmacogenomic biomarkers [br08341.html]
 Polymorphisms and germline mutations
  D00336
BRITE hierarchy
Other DBs
CAS: 10238-21-8
PubChem: 9234
ChEBI: 5441
ChEMBL: CHEMBL472
PDB-CCD: GBM[PDBj]
NIKKAJI: J3.430D
LinkDB All DBs
KCF data Show

ATOM        33
            1   C8y C    12.0400  -16.9400
            2   C8y C    12.0400  -18.3400
            3   C8x C    10.8500  -16.1700
            4   C5a C    13.2300  -16.2400
            5   C8x C    10.8500  -18.9700
            6   O2a O    13.2300  -19.0400
            7   C8y C     9.5900  -16.8700
            8   N1b N    14.4200  -16.9400
            9   O5a O    13.2300  -14.8400
            10  C8x C     9.5900  -18.2700
            11  C1a C    13.2300  -20.3700
            12  X   Cl    8.4000  -16.1700
            13  C1b C    15.6800  -16.2400
            14  C1b C    16.8700  -16.9400
            15  C8y C    18.0600  -16.2400
            16  C8x C    18.0600  -14.8400
            17  C8x C    19.2500  -16.9400
            18  C8x C    19.2500  -14.1400
            19  C8x C    20.5100  -16.2400
            20  C8y C    20.5100  -14.8400
            21  S4a S    21.7000  -14.1400
            22  N1b N    22.8900  -14.8400
            23  C5a C    24.0800  -14.1400
            24  N1b N    25.3400  -14.8400
            25  O5a O    24.0800  -12.7400
            26  C1y C    26.5300  -14.1400
            27  C1x C    26.5300  -12.7400
            28  C1x C    27.7200  -14.8400
            29  C1x C    27.7200  -12.0400
            30  C1x C    28.9100  -14.1400
            31  C1x C    28.9100  -12.7400
            32  O3c O    22.4000  -12.9276
            33  O3c O    21.0000  -12.9276
BOND        35
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 2
            5     2   6 1
            6     3   7 1
            7     4   8 1
            8     4   9 2
            9     5  10 1
            10    6  11 1
            11    7  12 1
            12    8  13 1
            13   13  14 1
            14   14  15 1
            15   15  16 2
            16   15  17 1
            17   16  18 1
            18   17  19 2
            19   18  20 2
            20   20  21 1
            21   21  22 1
            22   22  23 1
            23   23  24 1
            24   23  25 2
            25   24  26 1
            26   26  27 1
            27   26  28 1
            28   27  29 1
            29   28  30 1
            30   29  31 1
            31    7  10 2
            32   19  20 1
            33   30  31 1
            34   21  32 2
            35   21  33 2

» Japanese version

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