KEGG   COMPOUND: C22539
Entry
C22539                      Compound                               
Name
Complement C3(H2O);
Hydrated C3;
C3(H2O)
Sequence
(A chain)
SVQLTEKRMD KVGKYPKELR KCCEDGMREN PMRFSCQRRT RFISLGEACK KVFLDCCNYI
TELRRQHARA SHLGLARSNL DEDIIAEENI VSRSEFPESW LWNVEDLKEP PKNGISTKLM
NIFLKDSITT WEILAVSMSD KKGICVADPF EVTVMQDFFI DLRLPYSVVR NEQVEIRAVL
YNYRQNQELK VRVELLHNPA FCSLATTKRR HQQTVTIPPK SSLSVPYVIV PLKTGLQEVE
VKAAVYHHFI SDGVRKSLKV VPEGIRMNKT VAVRTLDPER LGREGVQKED IPPADLSDQV
PDTESETRIL LQGTPVAQMT EDAVDAERLK HLIVTPSGCG EQNMIGMTPT VIAVHYLDET
EQWEKFGLEK RQGALELIKK GYTQQLAFRQ PSSAFAAFVK RAPSTWLTAY VVKVFSLAVN
LIAIDSQVLC GAVKWLILEK QKPDGVFQED APVIHQEMIG GLRNNNEKDM ALTAFVLISL
QEAKDICEEQ VNSLPGSITK AGDFLEANYM NLQRSYTVAI AGYALAQMGR LKGPLLNKFL
TTAKDKNRWE DPGKQLYNVE ATSYALLALL QLKDFDFVPP VVRWLNEQRY YGGGYGSTQA
TFMVFQALAQ YQKDAPDHQE LNLDVSLQLP SRSSKITHRI HWESASLLRS EETKENEGFT
VTAEGKGQGT LSVVTMYHAK AKDQLTCNKF DLKVTIKPAP ETEKRPQDAK NTMILEICTR
YRGDQDATMS ILDISMMTGF APDTDDLKQL ANGVDRYISK YELDKAFSDR NTLIIYLDKV
SHSEDDCLAF KVHQYFNVEL IQPGAVKVYA YYNLEESCTR FYHPEKEDGK LNKLCRDELC
RCAEENCFIQ KSDDKVTLEE RLDKACEPGV DYVYKTRLVK VQLSNDFDEY IMAIEQTIKS
GSDEVQVGQQ RTFISPIKCR EALKLEEKKH YLMWGLSSDF WGEKPNLSYI IGKDTWVEHW
PEEDECQDEE NQKQCQDLGA FTESMVVFGC PN
(Disulfide bridge: 202-842)
(B chain)
SPMYSIITPN ILRLESEETM VLEAHDAQGD VPVTVTVHDF PGKKLVLSSE KTVLTPATNH
MGNVTFTIPA NREFKSEKGR NKFVTVQATF GTQVVEKVVL VSLQSGYLFI QTDKTIYTPG
STVLYRIFTV NHKLLPVGRT VMVNIENPEG IPVKQDSLSS QNQLGVLPLS WDIPELVNMG
QWKIRAYYEN SPQQVFSTEF EVKEYVLPSF EVIVEPTEKF YYIYNEKGLE VTITARFLYG
KKVEGTAFVI FGIQDGEQRI SLPESLKRIP IEDGSGEVVL SRKVLLDGVQ NPRAEDLVGK
SLYVSATVIL HSGSDMVQAE RSGIPIVTSP YQIHFTKTPK YFKPGMPFDL MVFVTNPDGS
PAYRVPVAVQ GEDTVQSLTQ GDGVAKLSIN THPSQKPLSI TVRTKKQELS EAEQATRTMQ
ALPYSTVGNS NNYLHLSVLR TELRPGETLN VNFLLRMDRA HEAKIRYYTY LIMNKGRLLK
AGRQVREPGQ DLVVLPLSIT TDFIPSFRLV AYYTLIGASG QREVVADSVW VDVKDSCVGS
LVVKSGQSED RQPVPGQQMT LKIEGDHGAR VVLVAVDKGV FVLNKKNKLT QSKIWDVVEK
ADIGCTPGSG KDYAGVFSDA GLTFTSSSGQ QTAQRAELQC PQPAA
(Disulfide bridge: A145-B537)
  Organism
Homo sapiens [HSA:718]
  Type
Peptide
Comment
C3 with a hydrolyzed thioester bond
Pathway
map04610  Complement and coagulation cascades
Network
nt06513  Complement cascade
LinkDB

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