KEGG   DRUG: MitomycinHelp
Entry
D00208                      Drug                                   

Name
Mitomycin (USP/INN);
Mitomycin C (JP17);
MMC;
Mitomycin (TN);
Muamycin (TN)
Product
  Generic
Formula
C15H18N4O5
Exact mass
334.1277
Mol weight
334.3272
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Source
Streptomyces caespitosus [TAX:53502]
Remark
Same as: C06681
Therapeutic category: 4231
ATC code: L01DC03
Product: D00208<JP/US>
Efficacy
Antineoplastic
  Disease
Glaucoma [DS:H00612]
Adenocarcinoma of the stomach or pancreas [DS:H00018 H00019]
Comment
DNA synthesis inhibitor
Target
DNA
Interaction
Drug interaction
Structure map
map07040  Antineoplastics - alkylating agents
map07042  Antineoplastics - agents from natural products
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L01 ANTINEOPLASTIC AGENTS
   L01D CYTOTOXIC ANTIBIOTICS AND RELATED SUBSTANCES
    L01DC Other cytotoxic antibiotics
     L01DC03 Mitomycin
      D00208  Mitomycin (USP/INN) <JP/US>
Therapeutic category of drugs in Japan [BR:br08301]
 4  Agents affecting cellular function
  42  Antineoplastics
   423  Antibiotics
    4231  Mytomycin C
     D00208  Mitomycin (USP/INN); Mitomycin C (JP17)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00208  Mitomycin C
  D00208  Mitomycin C for injection
Antineoplastics [br08340.html]
 D00208
BRITE hierarchy
Other DBs
CAS: 50-07-7
PubChem: 7847275
ChEBI: 27504
ChEMBL: CHEMBL105
DrugBank: DB00305
LigandBox: D00208
NIKKAJI: J64.512E
LinkDB All DBs
KCF data Show

ATOM        24
            1   C1z C    26.7153  -18.5085
            2   N1y N    25.8935  -19.6917
            3   C1y C    28.0734  -18.9398
            4   C1y C    25.8935  -17.3777
            5   C2y C    24.5646  -19.2603
            6   C1x C    26.7445  -20.7467
            7   C1y C    28.0967  -20.3444
            8   N1x N    29.3090  -19.6509
            9   C2y C    24.5646  -17.8557
            10  C1b C    26.3074  -16.0547
            11  C5x C    23.3581  -19.9714
            12  C5x C    23.3581  -17.1213
            13  O7a O    25.3573  -15.0289
            14  C2y C    22.1049  -19.2953
            15  O5x O    23.3581  -21.3645
            16  C2y C    22.0875  -17.8674
            17  O5x O    23.3990  -15.7574
            18  C7a C    25.7537  -13.6360
            19  C1a C    20.8694  -20.0006
            20  N1a N    20.8694  -17.1796
            21  N1a N    27.1700  -13.3270
            22  O6a O    24.8443  -12.5926
            23  O2a O    27.4153  -17.2960
            24  C1a C    28.8400  -16.6662
BOND        27
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 1
            7     3   8 1
            8     4   9 1
            9     4  10 1 #Up
            10    5  11 1
            11    9  12 1
            12   10  13 1
            13   11  14 1
            14   11  15 2
            15   12  16 1
            16   12  17 2
            17   13  18 1
            18   14  19 1
            19   16  20 1
            20   18  21 1
            21   18  22 2
            22    5   9 2
            23    6   7 1
            24    7   8 1
            25   14  16 2
            26    1  23 1 #Down
            27   23  24 1

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