| Entry |
|
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| Name |
Betamethasone (JP18/USP/INN);
Celestone (TN);
Rinderon (TN) |
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| Formula |
C22H29FO5
|
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| Exact mass |
392.1999
|
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| Mol weight |
392.46
|
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| Structure |
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| Simcomp |
|
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| Class |
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
Dermatological agent
DG03243 Atopic dermatitis agent
|
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| Remark |
| Therapeutic category: | 2454 |
| Product (DG00095): | D00244<JP> D00972<JP> D01357<JP/US> D01637<JP/US> D02032<JP> |
| Product (mixture): | D04447<JP> D10300<US> |
|
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| Efficacy |
Anti-inflammatory, Antirheumatic, Glucocorticoid receptor agonist |
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| Target |
|
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
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| Interaction |
|
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| Structure map |
| map07225 | Glucocorticoid and mineralocorticoid receptor agonists/antagonists |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
A07E INTESTINAL ANTIINFLAMMATORY AGENTS
A07EA Corticosteroids acting locally
A07EA04 Betamethasone
D00244 Betamethasone (JP18/USP/INN) <JP>
C CARDIOVASCULAR SYSTEM
C05 VASOPROTECTIVES
C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
C05AA Corticosteroids
C05AA05 Betamethasone
D00244 Betamethasone (JP18/USP/INN) <JP>
D DERMATOLOGICALS
D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
D07A CORTICOSTEROIDS, PLAIN
D07AC Corticosteroids, potent (group III)
D07AC01 Betamethasone
D00244 Betamethasone (JP18/USP/INN) <JP>
D07X CORTICOSTEROIDS, OTHER COMBINATIONS
D07XC Corticosteroids, potent, other combinations
D07XC01 Betamethasone
D00244 Betamethasone (JP18/USP/INN) <JP>
H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
H02 CORTICOSTEROIDS FOR SYSTEMIC USE
H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
H02AB Glucocorticoids
H02AB01 Betamethasone
D00244 Betamethasone (JP18/USP/INN) <JP>
R RESPIRATORY SYSTEM
R01 NASAL PREPARATIONS
R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
R01AD Corticosteroids
R01AD06 Betamethasone
D00244 Betamethasone (JP18/USP/INN) <JP>
R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
R03B OTHER DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES, INHALANTS
R03BA Glucocorticoids
R03BA04 Betamethasone
D00244 Betamethasone (JP18/USP/INN) <JP>
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01B ANTIINFLAMMATORY AGENTS
S01BA Corticosteroids, plain
S01BA06 Betamethasone
D00244 Betamethasone (JP18/USP/INN) <JP>
S01C ANTIINFLAMMATORY AGENTS AND ANTIINFECTIVES IN COMBINATION
S01CB Corticosteroids/antiinfectives/mydriatics in combination
S01CB04 Betamethasone
D00244 Betamethasone (JP18/USP/INN) <JP>
S02 OTOLOGICALS
S02B CORTICOSTEROIDS
S02BA Corticosteroids
S02BA07 Betamethasone
D00244 Betamethasone (JP18/USP/INN) <JP>
S03 OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS
S03B CORTICOSTEROIDS
S03BA Corticosteroids
S03BA03 Betamethasone
D00244 Betamethasone (JP18/USP/INN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
24 Hormones
245 Adrenal hormone preparations
2454 Fluorinated adrenocorticotropic hormones
D00244 Betamethasone (JP18/USP/INN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
DG00095 Betamethasone
D00244 Betamethasone
Dermatological agent
DG03243 Atopic dermatitis agent
D00244 Betamethasone
Drug classes [BR:br08332]
Anti-inflammatory
DG01955 Corticosteroid
D00244 Betamethasone
Dermatological agent
DG03243 Atopic dermatitis agent
D00244 Betamethasone
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C1 (GR)
D00244 Betamethasone (JP18/USP/INN) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D00244 Betamethasone
D00244 Betamethasone tablets
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
DG00095 Betamethasone
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 28
1 C2x C 6.7900 -14.9100
2 C5x C 6.7900 -16.3100
3 C2x C 8.0024 -17.0100
4 C2y C 9.2149 -16.3100
5 C1z C 9.2149 -14.9100
6 C2x C 8.0024 -14.2100
7 C1x C 10.4273 -17.0100
8 C1x C 11.6397 -16.3100
9 C1y C 11.6397 -14.9100
10 C1z C 10.4273 -14.2100
11 C1y C 12.8522 -14.2100
12 C1z C 12.8522 -12.8100
13 C1x C 11.6397 -12.1100
14 C1y C 10.4273 -12.8100
15 C1x C 15.2770 -14.2100
16 C1y C 15.2770 -12.8100
17 C1z C 14.0646 -12.1100
18 C1a C 9.2149 -13.5100
19 O1a O 9.2169 -12.1112
20 C1a C 12.8522 -11.4100
21 C1a C 16.4766 -12.1173
22 C5a C 14.0646 -10.3600
23 X F 10.4273 -15.6100
24 O1a O 15.2770 -11.4100
25 O5x O 5.5776 -17.0100
26 O5a O 15.2811 -9.6577
27 C1b C 12.8562 -9.6623
28 O1a O 11.6627 -10.3516
BOND 31
1 1 2 1
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 1
6 1 6 2
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 5 10 1
12 9 11 1
13 11 12 1
14 12 13 1
15 13 14 1
16 10 14 1
17 11 15 1
18 15 16 1
19 16 17 1
20 12 17 1
21 5 18 1 #Up
22 14 19 1 #Up
23 12 20 1 #Up
24 16 21 1 #Up
25 17 22 1 #Up
26 10 23 1 #Down
27 17 24 1 #Down
28 2 25 2
29 22 26 2
30 22 27 1
31 27 28 1
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