Entry |
|
Name |
Cidofovir (USAN/INN); Cidofovir dihydrate; Vistide (TN) |
Product |
|
Generic |
|
Formula |
C8H14N3O6P. 2H2O
|
Exact mass |
315.0832
|
Mol weight |
315.22
|
Structure |

|
Simcomp |
|
Class |
Antiviral
DG01937 Anti-cytomegalovirus agent
|
Remark |
Product (DG00648): | D00273<US> |
|
Efficacy |
Antiviral, DNA polymerase inhibitor |
Disease |
Cytomegalovirus retinitis [DS: H00368] |
Target |
HCMV DNA polymerase [KO: K18964] |
Pathway |
|
Interaction |
|
Structure map |
|
Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J05 ANTIVIRALS FOR SYSTEMIC USE
J05A DIRECT ACTING ANTIVIRALS
J05AB Nucleosides and nucleotides excl. reverse transcriptase inhibitors
J05AB12 Cidofovir
D00273 Cidofovir (USAN/INN) <US>
USP drug classification [BR:br08302]
Antivirals
Anti-cytomegalovirus (CMV) Agents
Cidofovir
D00273 Cidofovir (USAN/INN)
Drug groups [BR:br08330]
Antiviral
DG01937 Anti-cytomegalovirus agent
DG00648 Cidofovir
D00273 Cidofovir
Drug classes [BR:br08332]
Antiviral
DG01937 Anti-cytomegalovirus agent
D00273 Cidofovir
Antimicrobials [BR:br08307]
Antivirals
Genome replication inhibitor
Herpesvirus DNA polymerase inhibitor
D00273 Cidofovir (USAN/INN) <US>
Drug groups [BR:br08330]
Antiviral
DG01937 Anti-cytomegalovirus agent
DG00648 Cidofovir
Antimicrobials abbreviations [BR:br08327]
Antivirals
Genome replication inhibitor
Herpesvirus DNA polymerase inhibitor
DG00648 Cidofovir
|
Other DBs |
|
LinkDB |
|
KCF data |
ATOM 20
1 N4y N 18.4099 -16.1647
2 C1b C 18.4230 -17.5148
3 C8y C 19.6284 -15.4528
4 C8x C 17.1970 -15.4556
5 C1c C 17.2044 -18.2266
6 N5x N 19.6154 -14.1027
7 O5x O 20.7714 -16.1619
8 C8x C 17.2539 -14.1055
9 O2a O 15.9915 -17.5175
10 C1b C 17.2529 -19.5161
11 C8y C 18.4025 -13.3936
12 C1b C 14.8784 -18.1688
13 N1a N 18.4239 -12.1042
14 P1b P 13.6655 -17.4597
15 O1c O 12.8854 -18.7939
16 O1c O 12.2706 -16.6442
17 O1c O 14.5164 -16.0041
18 O1a O 18.3810 -20.1967
19 O0 O 23.8384 -18.7532
20 O0 O 23.8384 -18.7532
BOND 18
1 1 2 1
2 1 3 1
3 1 4 1
4 2 5 1
5 3 6 1
6 3 7 2
7 4 8 2
8 5 9 1 #Up
9 5 10 1
10 6 11 2
11 9 12 1
12 11 13 1
13 12 14 1
14 14 15 1
15 14 16 1
16 14 17 2
17 8 11 1
18 10 18 1
BRACKET 1 21.8400 -19.6000 21.8400 -17.5700
1 24.2900 -17.5700 24.2900 -19.6000
1 2
ORIGINAL 1 19
REPEAT 1 20
|