Cytomegalovirus (CMV) is a double-stranded DNA virus of the Herpesviridae family acquired by late childhood in the majority of individuals. Primary infection is nonspecific but after that the virus becomes latent in multiple organs and can later be reactivated. CMV is an important and common cause of mortality and morbidity in immunocompromised patients such as those with HIV/AIDS or transplant recipients on immunosuppressive therapy.
Category
Viral infectious disease
Brite
Human diseases in ICD-11 classification [BR:br08403]
01 Certain infectious or parasitic diseases
Certain other viral diseases
1D82 Cytomegaloviral disease
H00368 Cytomegalovirus infection
Pathway-based classification of diseases [BR:br08402]
Signal transduction
nt06518 JAK-STAT signaling
H00368 Cytomegalovirus infection
nt06516 TNF signaling
H00368 Cytomegalovirus infection
nt06522 mTOR signaling
H00368 Cytomegalovirus infection
Cellular process
nt06524 Apoptosis
H00368 Cytomegalovirus infection
Immune system
nt06520 CGAS-STING signaling
H00368 Cytomegalovirus infection
nt06533 Chemokine signaling
H00368 Cytomegalovirus infection
Genome-based classification of infectious diseases [BR:br08401]
Viral infections
Infections caused by dsDNA viruses
H00368 Cytomegalovirus infection
